RE: emergen-c and other medicines (Dr. Olney on aspartic acid (aspartate).

[Guest guest]

If it says on the label: " aspartic acid " you shouldn't use it. You

don't even have to consider what I say, this is what Dr. Russell

Blaylock, neurosurgeon, says. " Excitotoxins: The Taste That

Kills " , www.russellblaylockmd.com - an entire book on aspartic acid

and glutamate, both excitotoxins, and a few others like

cysteine. Everyone who cares about health should read it. He also

has an excellent newsletter.

 

You simply can't isolate aspartic acid. This is why Dr. John Olney

fought so hard to stop the approval of aspartame. He did this study

and at that time founded the field of neuroscience called

excitotoxicity. (I'll continue below the study.) Also, the

combination of aspartic acid and glutamate can really damage a baby's

brain. You should read Dr. Olney's 49 page report on www.mpwhi.com,

front page banner. It was written to the Board of Inquiry of the

FDA, who agreed with it. Read on.

 

 

 

Brain Damage in Infant Mice Following Oral Intake of Glutamate,

Aspartate or Cysteine

 

By John W. Olney, MD

 

 

Striking degenerative changes in the infant mouse retina after

subcutaneous treatment with monosodium glutamate (MSG) were reported

by Lucas and Newhouse in l957(1). Other studies (2-4) established

that the process of retinal degeneration induced by MSG treatment is

a remarkably acute and irreversible form of neuronal pathology.

Recently it was found that a similar process of acute neuronal

necrosis occurs in several regions of the infant mouse brain after

subcutaneous treatment with MSG, and that animals treated with high

doses in infancy tend to manifest obesity and neuroendocrine

disturbances as adults (7,8). The arcuate nucleus of the hypothalamus

is an area particularly vulnerable to glutamate induced damage in

infant animals of several spices (mice and rats (7), rabbits and

chicks and the rhesus monkey (3) ), In mice, which have been studied

more extensively for MSG induced disturbances than other species, the

infant animal suffered hypothalamic damage from a relatively low

subcutaneous dose (0.5 g/kg of body weight) (7).

 

Because of the widespread practice of weaning human infants on foods

which are not only rich in natural glutamate content but may contain

substantial quantities of glutamate (MSG) added for flavouring

(10,11), it is important to establish whether damage to the infant

central nervous system could follow from oral as well as from

parenteral administration of glutamate (12). We describe here

experiments which demonstrate hypothalamic damage in infant mice

following relatively low oral doses of glutamate, and also report

that orally administered aspartate and cysteine can induce retinal

and hypothalamic damage.

 

Seventy-five Webster Swiss albino mice, 10 to 12 days old, were given

single oral doses of a 10 per cent aqueous solution of MSG at one of

5 dose levels (0.25, 0.5, 0.75, 1.0 or 2.0 g/kg). Ten control animals

were intubated but given no treatment, and an additional 46 were

given single oral doses of other test compounds, as shown in Table 1.

Accurate dosage control was ensured by use of an improvised flexible

gastric tube inserted gently through the mouth and esophagus into the

stomach. About 5 h after treatment, each animal was anaesthetized

with chloral hydrate and killed by perfusion fixation of the central

nervous system with 1.5 per cent glutaraldehyde and 1 per cent

paraformaldehyde in 0.1 M cacodylate buffer. After 15 min of

perfusion, the retinas and brain areas of interest were further fixed

in osmium tetroxide and processed by a technique described elsewhere'

which permits alternative examination of any specimen by either light

or electron microscopy. To provide a rough 3 g/kg., Aspartate and

cysteine, however, were striking exceptions because each animal

treated with these compounds developed both retinal and hypothalamic

lesions which seemed identical to those which are usually found after

treatment with MSG. The possibility that glutamate and aspartate are

additive in their toxic effect was suggested by the observation that

every one of eight animals treated orally was a mixture of MSG (0.5

g/kg) and sodium aspartate (0.5 g/kg) developed a degree of

hypothalamic damage characteristically seen in animals treated with

either agent as l g/kg (Table 1).

 

Curtis (13) and others have found that glutamate, aspartate and

cysteine comprise a select group of amino acids (the

" neuroexcitatory " amino acids) which can depolarize nerve membranes.

Whether the striking ability of this select group of compounds to

induce neuronal necrosis in the immature central nervous system

relates to their ability to depolarize nerve membranes need further

study. Because glutamate is a naturally occurring constituent of

dietary protein there has been little tendency to question its safety

for human infant consumption. But, in our experiments, both glutamate

and aspartate are toxic to the infant mouse at relatively low levels

of oral intake and, when taken together, these common amino acids

have an additive brain damaging effect. Contrary to conclusions which

others have reached from studies on adult animals (12) these

experiments with tube fed infant animals raise serious questions

concerning the advisability of supplementing the human infant diet with MSG.

 

This work was supported by grants from the National Institutes of

Mental Health, U.S. Public Health Service.

 

John W. Olney, M.D., OI-Lan Ho Washington University School of

Medicine, St. Louis, Missouri 63110: Received January 5; revised

April 16, l970.

 

References

 

* Lucas, D.R. and Newhouse, J.P., Amer. Med. Assoc. Arch.

Ophthal, 58, l93 (l957)

* Potts, A.M., Modrell, K. W., and Kingsbury, C., Amer. J.

Ophthal., 50, 900 (l960)

* Freedman, J. K., and Potts, A.M. Invest. Ophthal., 1, 118 (l962)

* Freedman, J. K. and Potts, A.M. Invest. Ophthal., 2, 252 (l963)

* Cohen, A. I. Amer. J. Anat., 120, 319 (l967)

* Olney, J. W., J. Neuropath. Exp. Neurol., 28, 455 (1069).

* Olney, J. W., Science, 164, 719 (l969)

* Redding, T. W., and Schally, A. V., Fed. Proc., 29, 755 (l970).

* Olney, J. W., and Sharpe, L. G., Science, l66, 380 (l969)

* Gerber Products, Inc., Hearings before the Select Committee on

Nutrition and Human Needs of the US Senate, 13A, 4170 (July l969).

* Lowe, C. U., Science, 167,1016 (l970).

* Blood, F. R., Oser, B. L. and White, P. L. Science 165, l028 (l969)

* Curtis, D. R. and Crawford, J. M., Ann. Rev. Pharm., 9, 209 (l969).

 

End of Study

______________________

Dr. Olney and Dr. Madelin Price, a biochemist with impeccable

credentials on her own, who worked with Dr. Olney for 38 years have

done many studies on aspartic acid. I have several.

 

Just like you can't isolate aspartic acid because its an

excitotoxin, neither can you isolate phenylalanine that is in

aspartame. Granted its 50% in aspartame which is why it does so much

damage because you might have 5% in meat or milk or whatever, but

this really floods the brain, lowering the seizure threshold and

depleting serotonin. Isolated in any amount it a neurotoxin. The

reason I'm telling you this is people will argue about the small

amount of phenylalanine in products, and companies will argue with

you, and they will give all sorts of reasons. Of course,

phenylketonurics who can't metabolize phenylalanine could really be

damaged, the reason for the PKU warning on aspartame. Anyway, I've

passed some of these arguments on to Dr. Madelin Price who retired a

couple of years ago after working by Dr. Olney's side for almost four

decades. She always wrote back and said if its phenylalanine you

can't isolate it. The last time I sent her a really big argument I

really had to smile with her answer: " Phenylalanine is phenylalanine

is phenylalanine. It cannot be used in any product! " This is the

same thing as aspartic acid.

The reason aspartame is so deadly is the components are either

neurotoxic or excitoxic. It's an excitoneurotoxic carcinogenic

drug. The molecule breaks down to DKP which is a brain tumor agent.

Put it this way after working all these years with the experts

and reading everything they write, I personally would not use any

product with aspartic acid or phenylalanine. Anyone who does should

do it at their own risk.

All my best, Betty www.mpwhi.com, www.dorway.com, www.wnho.net,

www.holisticmed.com/aspartame

 

 

 

 

At 05:13 PM 8/10/2008, Tony De Angelis wrote:

 

>While free aspartic acid may be a problem ascorbates are

>not. Ascorbate is a primary transporter of minerals into the the

>cell membrane. Emergen-C contains ascorbates.

>

>--- On Sun, 8/10/08, Rebecca Price <raprice49 wrote:

>Rebecca Price <raprice49

>RE: Re: emergen-c and other medicines

>health_and_healing

>Sunday, August 10, 2008, 4:30 PM

>

>I generally agree with the side that says 'go natural', but in the

>case of Emergen-C, I've used it for many years to very good

>effect. Throw it my way. There are times when I just don't have

>time or stomach room for two oranges, 3 apples and a plate of bell

>peppers--life is really good at interfering with our good plans. At

>times of flagging spirits or energy and/or the threat of a

>cold/flu...or even just an overdose of stress--a little packet of

>Emergen-C is a real help. I know too many who believe exactly the

>same to throw out all supplements.

>

>Which leads me to another thought: not all medicines or current

>medical practices are wrong-bad-unsupport able.

>There are times when a good doctor and pharmaceuticals are the only

>thing that will save your b*tt. That's why they got the position of

>power they currently enjoy. IMO, the idea is to not rely too heavily

>on any one source of remedy and not be too extreme in any

>view...there is good and bad in all.

>

>

>----------