Guest guest Posted July 16, 2009 Report Share Posted July 16, 2009 Everyone this is truly the FIND OF THE YEAR. This moves ZEO GOLD to the front pages of any interested person looking for reasons to add Zeolite to whatever treatments they are doing! This fantastically well written review of Zeolite from Sloan Kettering has all of the references fully linked so all you have to do is click on them. Garry F. Gordon MD,DO,MD(H) President, Gordon Research Institute www.gordonresearch.com http://www.mskcc.org/mskcc/html/69424.cfm MECHANISM OF ACTION Zeolites have ion-exchanging and adsorption properties. Zeolite granules, when used externally on wounds, can stop bleeding and promote clotting through the absorption of water (2) (3). Zeolites are thought to adsorb pathogenic microbials, glucose, and alcohol in the stomach and intestine and have been proposed for use in diarrhea (4), diabetes (5), and hangover (8) . Due to their alkaline nature, zeolites have pH buffering effects. They can adsorb nitrosamines in acidic solution (12) leading to claims that they can also be used as anticancer treatment by removing carcinogenic substances in the stomach. However, such effects have not been substantiated in humans. A few in vitro studies indicate that micronized zeolite inhibited protein kinase B; and induced expression of tumor suppressor proteins (9). In animal studies, micronized zeolite product was shown to reduce metastasis and increase the effect of doxorubicin due to its antioxidant property (13). It also increased peritoneal macrophages after intraperitoneal application and stimulate graft-versus-host reaction (14). Precise mechanisms of action remain largely unknown. Micronized zeolite can affect brain serotonergic receptors activities of mammary carcinoma bearing mice (15). However, the clinical implication of this effect in humans is unclear. Zeolite supplementation did not prolong survival in tumor-bearing animals (16). Zeolites may have both immunosuppressing and immunostimulating effects. In animal studies, they caused decline of GM-CFU in the bone marrow (16) but increase graft-versus-host (GvH) reaction (14). Zeolite products have other benefits when used in animal feed: they increase mineral utilization (17), reduce heavy metals induced anemia (18) and reduce aflatoxin toxicity (19). None of these benefits are applicable to humans. PURPORTED USES • Treatment of diarrhea A drug containing zeolite was developed for diarrhea in Cuba • Anticancer therapy In vitro and animal studies suggest anticancer properties, but there is no clinical data to validate use of Zeolites for cancer. • Antioxidant Animal studies showed that Zeolites may have antioxidant properties • Immunoenhancer Data from animal studies demonstrated that zeolites can both stimulate and suppress the immune system REFERENCES [1] Elmore AR. Final report on the safety assessment of aluminum silicate, calcium silicate, magnesium aluminum silicate, magnesium silicate, magnesium trisilicate, sodium magnesium silicate, zirconium silicate, attapulgite, bentonite, Fuller's earth, hectorite, kaolin, lithium magnesium silicate, lithium magnesium sodium silicate, montmorillonite, pyrophyllite, and zeolite. Int J Toxicol 2003; 22 Suppl 1:37-102. [2] Ahuja N, Ostomel TA, Rhee P, et al. Testing of modified zeolite hemostatic dressings in a large animal model of lethal groin injury. The Journal of trauma 2006; 61(6):1312-20. [3] Alam HB, Chen Z, Jaskille A, et al. Application of a zeolite hemostatic agent achieves 100% survival in a lethal model of complex groin injury in Swine. The Journal of trauma 2004; 56(5):974-83. [4] G. Rodriguez-Fuentes MM, A. Iraizoz, I, Perdomo, B. Cedre. Enterex: Anti-diarrheic drug based on purified natural clinoptilolite. Zeolites 1997;19:441-8. [5] Concepcion-Rosebal B, Rodriges-Fluentes, G., Simon-Carballo, R. Development and featuring of the zeolitic active principle FZ: a glucose adsorbent. Zeolites 1997;19(1):47. [6] Young SW, Qing F, Rubin D, et al. Gadolinium zeolite as an oral contrast agent for magnetic resonance imaging. J Magn Reson Imaging 1995; 5(5):499-508. [7] Zeolite Austism Study 2007 http://www.zeoliteautismstudy.com (accessed July 24, 2008) [8] Reuters. A New Cure for Hangover. CBS News 2002. (accessed July 24, 2008) [9] Pavelic K, Hadzija M, Bedrica L, et al. Natural zeolite clinoptilolite: new adjuvant in anticancer therapy. J Mol Med 2001; 78(12):708-20. [10] Sahin AA, Coplu L, Selcuk ZT, et al. Malignant pleural mesothelioma caused by environmental exposure to asbestos or erionite in rural Turkey: CT findings in 84 patients. Am J Roentgenol 1993; 161(3):533-7. [11] Baris YI, Grandjean P. Prospective study of mesothelioma mortality in Turkish villages with exposure to fibrous zeolite. J Natl Cancer Inst 2006; 98(6):414-7. [12] Zhou CF, Zhu JH. Adsorption of nitrosamines in acidic solution by zeolites. Chemosphere 2005 58(1):109-14. [13] Zarkovic N, Zarkovic K, Kralj M, et al. Anticancer and antioxidative effects of micronized zeolite clinoptilolite. Anticancer Res 2003 23(2B):1589-95. [14] Pavelic K, Katic M, Sverko V, et al. Immunostimulatory effect of natural clinoptilolite as a possible mechanism of its antimetastatic ability. Journal of cancer research and clinical oncology 2002;128(1):37-44. [15] Muck-Seler D, Pivac N. The effect of natural clinoptilolite on the serotonergic receptors in the brain of mice with mammary carcinoma. Life sciences 2003 Sep 5;73(16):2059-69. [16] Martin-Kleiner I, Flegar-Mestric Z, et al. The effect of the zeolite clinoptilolite on serum chemistry and hematopoiesis in mice. Food Chem Toxicol 2001; 39(7):717-27. [17] Watkins KL, Southern LL. Effect of dietary sodium zeolite A on zinc utilization by chicks. Poultry science 1993; 72(2):296-305. [18] Pond WG, Yen JT. Protection by clinoptilolite or zeolite NaA against cadmium-induced anemia in growing swine. Proc Soc Exp Biol Med 1983; 173(3):332-7. [19] Kubena LF, Harvey RB, Huff WE, et al. Efficacy of a hydrated sodium calcium aluminosilicate to reduce the toxicity of aflatoxin and diacetoxyscirpenol. Poultry science 1993; 72(1):51-9. [20] Eriksson I. Body Detox of Volcanic Ash Cause Cancer. Medical News Today 2004. (accessed July 24, 2008) [21] Kaufman H, inventor; Lifelink Pharmaceuticals Inc, assignee. Epithelial Cell Cancer Drug. US Patent 6,288,045. September 11, 2001. (accessed July 24, 2008) **************Can love help you live longer? Find out now. (http://personals.aol.com/articles/2009/02/18/longer-lives-through-relationships\ /?ncid=emlweu slove00000001) Quote Link to comment Share on other sites More sharing options...
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