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(NutraSweet/Equal, etc.) can precipitate Parkinson's

(Michael J. Fox)

 

---

 

 

Dear Oprah,

 

Today, you interviewed Michael Fox, a former Diet Pepsi

spokesman. Informants say he is addicted to it. Indeed, how could

Michael Fox develop Parkinson's at the age of 30, an old man's

disease? But aspartame

(NutraSweet/Equal, etc.) can precipitate Parkinson's and as a

neurotoxic

drug even interacts with L-dopa. And

then there was Millie and Morton Kondracke with Millie also

developing

Parkinson's at an age too young for the disease. In fact, it was

mentioned

that her child has a learning disorder and aspartame is a large

trigger

of

ADD. Did she use it during pregnancy. A recent study in Norway has

shown

 

that aspartame destroys the brain, especially in the areas of

learning. This certainly accounts for the global epidemic of

Attention

Deficit Disease. Denise developed Multiple Sclerosis at age 34, the

last

 

lady you interviewed yesterday. Below is a recent study of someone

who

was told she had MS but note the results when she abstained from

aspartame.

 

What is the common denominator in these folks, and three others who

worked

with Michael Fox and also developed Parkinson's Disease? You're

looking

for a neurotoxin/excitotoxin. An excitotoxin is a product that

literally

 

stimulates the neurons of the brain to death causing brain damage of

varying degrees. It was the famed Dr. John Olney who founded the

field

of

neuroscience called excitotoxicity. He did studies on aspartic acid,

40%

 

of aspartame, and found it caused lesions in the brains of mice. It

is

an

excitotoxin. Neurosurgeon Russell Blaylock, M.D., wrote the book on

it,

Excitotoxins: The Taste That Kills, www.amazon.com He discusses

Parkinson's Disease at length.

 

Dr. Blaylock gives several points on the disease. He

says " Parkinson's

Disease is a disorder whose cause appears from substantial evidence,

to

be

related to excitotoxicity. These toxins destroy the cells in the

brain

central to this disease. Excitotoxins cause these brain cells to

generate

enormous amounts of free radicals. This is true of MSG and aspartic

acid

 

(aspartame).There is substantial circumstantial evidence that

dietary

excitotoxins, including aspartame, can aggravate these destructive

changes

in the Parkinson's brain. The additional toxins - DKP, aspartate,

methanol, formaldehyde and formic acid - add to this injury. Recent

evidence demonstrates that the aspartame product, formaldehyde -

accumulates within cells and damages protein and DNA. "

 

Aspartame is being used by 2/3rds of the population today and 40% of

our

 

children, and is a deadly neurotoxic drug. It interacts with just

about

every drug used to treat the symptoms and diseases it triggers. How

could

the FDA allow this? Here is information from former FDA

Investigator,

Arthur Evangelista on how the FDA is suppose to handle investigation

of

neurotoxins:

 

FDA Toxicolgy Draft on Food Additives

Toxicological Principles For Safety Assessment of Direct Food

Additives

and Color Additives Used in Foods

Redbook II DRAFT 1993

U.S. Food and Drug Administration

Center for Food Safety and Applied Nutrition

 

This document...is intended to provide guidance regarding criteria

used for safety assessment of direct food additives and color

additives

used in food......

Chapter V: pg. 149

A. Introduction

" The Agency (FDA) recognizes that information about metabolism and

pharmacokinetics, neurotoxicity, and immunotoxicity are significant

endpoints in assessing the safety of direct food additives and color

additives used in food.... "

1. Metabolism and Pharmacokinetics

" FDA believes that data from studies on absorption, distribution,

metabolism, and excretion of chemicals can provide insight into

mechanisms

of toxicity and are essential in the design and evaluation of

results

from

other toxicity studies. Such studies should be provided for all

direct

food additives and

color additives used in foods that are assigned to Concern Levels II

or

III.

 

Recommendation for obtaining data on the metabolism and

pharmacokinetics

 

of these substances are presented in this document. In general,

the agency recommends that this information be obtained before

subchronic

and chronic toxicity tests are begun. "

C. Neurotoxicity Studies

paragraph 3:

" Until recently, neurotoxicity was equated with neuropathy involving

frank

neuropathological lesions or overt neurological dysfunctions, such

as

seizure, paralysis or tremor. " Examples of chemically induced

neuropathy

 

in humans

(for example, from exposure to lead, organic mercury, hexane, carbon

disulfide, and tri-ortho-cresylphosphate) emphasize the need for

assessing

the neurotoxic potential of chemicals to which humans may be

exposed.

Although neuropathy is

appropriately recognized as a manifestation of neurotoxicity, it is

now

clear that there are numerous other signs of nervous system

toxicity.

Motor incoordination, sensory deficits, learning and memory

dysfunctions,

changes in emotion and altered states of arousal are also recognized

as

indices of neurotoxicity. Continued reliance on neuropathy as the

primary

criterion of neurotoxicity is overly simplistic and may

significantly

underestimate the neurotoxic potential of a chemical in adult or

developing organisms. "

 

paragraph 8:

" Because of the impact that nervous system toxicity can have on

human

health, assessing the neurotoxic potential of a chemical proposed

for

use

in food or color additive should be an essential element in that

chemical's toxicological profile.... "

 

Commentary by: Arthur Evangelista,

former FDA Investigator

The written words of this text, serving as a guide to Food and Drug

Regulatory Policies, is noble, and scientifically accurate...with

one

exception. The FDA has disregarded its own rulings, guidelines, and

policies for protecting the public health, and has, instead, become

partners with industry at such a level, which basically renders this

well

written draft, totally useless. Although, FDA is not alone in

disregarding

its policies in favor of politics and corporate influences, is

has, nevertheless, created a corrupted system of public health

regulations

which has served to only exacerbate the complications of chemical

additives in foods, and collaborate with industry for their profits

and

market gains.

 

In fact, Aspartame (aka: Nutrasweet, Equal, Spoonful, Canderal,

Benevia,

 

et al) a neurotoxin by nature, is extremely damaging to the central

nervous system, and subsequent neural-dependent systems like

endocrine

and

liver functions. That the very fact aspartame is in our food supply,

implies an un-regulatory agency

which better serves the industry that it was supposed to be

regulating.

Anyone thinking about how the United States government, and

political

muscle has assisted firms, like G.D. Searle, Monsanto, and other

agri-chemical companies nationally and internationally, has got to

ask,

Why ? Since when do government agencies actively support and promote

private industry on such a high level ?

The reason is due to the political nature of these businesses, and

their

 

very close

association to government agencies and political bodies. In fact,

many

of

these firms are run with former or active members of government, and

vise-versa, when employees " leave " the firm, and join the regulatory

or

political agendas of our government, as federal workers. We have a

cancer

in our society, and this is the cause of the cancer.... " the wolf is

watching the sheep " . And, as in the function of FDA, this does not

work;

nor will it ever work. It is not only impractical, but

ludicrous. Enforcement of industry, can not come from close

association

or

within industry. It is not possible to objectively enforce

regulations

when collaboration exists between government agencies and

corporations.

It

also does not help when corporations can infuse large amounts of

PAC,

soft-money contributions, and other types of graft or bribery for

politicians, who in turn, affect the regulatory policies through

actions

 

in Congress. As a former FDA official, I have personally witnessed

watering down of public-benefit policies, only to render them

ineffective.

I have witnessed reports being altered, statements changed, and lies

told,

regarding investigations and regulation applications. This is a

corrupted

system of public health, and the cancer is in the policy makers and

influences of corporate money flowing to the White House.

Arthur Evangelista (orwi-)

April 4, 2002

" If we are to guard against ignorance and remain free,

it is the responsibility of every American to be informed. "

-- Thomas Jefferson

 

Unfortunately, Oprah, those responsible to solve the problem ARE the

problem!

 

In a conversation with Dr. James Bowen after your show he said: " The

aspartame molecule is a highly synergized combination of

neurotoxins.

The

first of these is wood alcohol or methanol. For over a century this

molecule, in and of itself, has been known to cause virtually all

the

degenerative changes from chronic alcoholism. In addition, any

exposure

to this, even in trace amounts is noted to result in dementia,

insanity,

 

blindness, retinal deterioration, degenerative disease of virtually

every

system of the body and various autoimmune disorders and is often

fatal. Methanol is noted as the number one chemical that causes

autoimmune disorders of the pancreas and myelin sheath.

 

The FDA rules do not allow any methanol to be incorporated into

foods. Moreover, any chemical containing any amount of methanol must

have

a poison label displayed prominently on it with a skull and

crossbones

prominently displayed and the words " warning poisonous, contains

methanol,

methyl alcohol, do not drink, get on skin or inhale

vapors. Warning: Cannot be made non poisonous. " The synergism

between

methanol and the other poisonous elements in NutraSweet end up

producing

 

an alcohol poisoning, about 20,000 times as potent as regular old

sipping

alcohol, ethanol. In the digestive tract aspartame is broken down

into

about ten other poisons, so normally would not be absorbed as the

entire

 

intact molecule from the digestive tract. Not everybody has

efficient

digestion and may get some directly from the digestive tract.

Moreover,

some forms its isomer diketopiperazine both in the can and in the

digestive tract. This diketopiperazine form, which is the most toxic

form

of aspartame, is absorbed intact directly from the digestive tract.

 

Also, in some amount, perhaps 1 milligram or so, aspartame is

absorbed

directly through the mouth while drinking a glass of pop. This is

called

 

buccal absorption. The poisonous potential of the aspartame molecule

is

so great, that even this small amount of aspartame is a significant

poisoning. People who have been sensitized from aspartame poisoning

will

 

often react in a matter of a few seconds when they first start using

some

inadvertently. This demonstrates the potency of the very small

amount

absorbed buccally. The aspartic acid component of the molecule is a

dicarboxylic amino acid excitotoxin. The phenylalanine isolate

poisoning

 

from the molecule renders 3 damages to the brain. One is the PKU

effect,

 

the second is malnutrition of the brain by virtue of competitive

inhibition at the blood brain barrier and third, by direct amino

acid

dynamics at enzymes sites it biochemically suppresses the formation

of

serotonin and dopamine. The summation of these ill effects results

in a

lot of people who get MS and Parkinson Disease directly from

aspartame

exposure. It has been my personal experience that people afflicted

with

neurologic disorders such as MS, Parkinson's disease and Lou Gehrigs

will

markedly deteriorate if they start and use aspartame. Stopping it

almost

 

always results in improvement. However, because of aspartame induced

chemical hypersensitivity disease they are likely to have flares in

response to numerous other chemical exposures that would otherwise

seem

trivial. Please see articles on www.dorway.com I wrote on " sperm

warfare "

and " punditry and Palsies " , and I do have one on chemical

hypersensitivity. Many others get these diseases directly from the

metabolic poisoning and the autoimmune damages inflicted by

aspartame. The fact NutraSweet radically depresses dopamine levels

and

dopamine production in the brain means from that biochemical

prospective

 

alone that its use will nullify the action of anti-Parkinson

medications. James Bowen, M.D. "

 

Three congressional hearings and continued outcry and outrage from

the

public has done nothing to convince the FDA they must be concerned

with

safe food and drugs instead of loyalty to industry and its funds. Ed

Horton of the Lancet said in an article in May that the FDA takes

money

from industry and endangers the lives of the public. So as would be

expected with this neurotoxic drug in an estimated 9000 products and

climbing, we are now faced with what may be one of the largest

plagues

in

world history, already declared by H. J. Roberts, M.D. who in l984

was

selected as the Best Doctor in the US. He has also provided a

medical

text for consumers and physicians titled Aspartame Disease: An

Ignored

Epidemic, www.aspartameispoison.com or www.sunsentpress.com or 1 800

814

-

9800. No one will be able to put this medical text down as you read

about the FDA, legal, corporate and bureaucratic obstacles, confused

health care professionals, flawed research, historical misgivings

about

aspartame, bureaucratic, political and corporate complexities and

the

real

story of how Searle/Monsanto got away with mass poisoning consumers

in

at

least 100 countries of the world. There are so many symptoms and

diseases

in this 1038 page book, 8 1/2 by 11, triggered by aspartame, that a

review by the Journal of Neurosurgery said it was like reading the

PDR

of

adverse reactions.

 

Dr. Roberts goes in depth about aspartame and Parkinson's Disease.

Under

 

Pathophysiologic Considerations he says the " pacemaker " for

essential

tremor has been localized among serotonin-activated neurons in the

inferior olivary nucleus (Longo l985). The bilaterally increased

glucose

 

metabolism therein, demonstrated by position-emission topographic

(PET)

studies in patients with essential tremor (Boecker l998) probably

renders

these areas more vulnerable to the metabolic effects of aspartame. "

 

He says: " The alteration of serotonin and dopamine concentrations in

the

 

brain by phenylalanine and aspartame are reviewed in Chapter XXIII

but

the

following observations are germane:

 

* The enzyme phenylalanine hydroxylase converts phenylalanine to

tyrosine. Tyrosine is first transformed into dihydroxyphenylalanine

(levodopa), and then to dopamine.

* The two dopamine receptor subtypes (D1 and D2) exert synergistic

effects on the firing rates of basal ganglia neurons (Walter l987).

* The importance of dopaminergic pathways in severe tremor is

further

suggested by the effectiveness of levodopa in treating both

parkinsonism

 

and " restless legs " (von Scheele l986).

* There is a reduction of brain dopamine in the presence of high

concentrations of phenylalanine (Congressional Record-Senate l985b,

p. S

 

10846).

* Chronic exposure to excess phenylalanine and aspartic acid can

decrease

the levels of serotonin and other neurotransmitters within several

regions

of the brain. These changes, presumably compensatory adaptive

mechanisms,

may disturb important diurnal variations associated with feeding and

the

 

light/dark cycle.

* An ad by G. D. Searle & Company in the Journal of the American

Medical

 

Association (Dec 16, l986) implied that excess activity of these

excitatory amino acids could cause nerve cell destruction resembling

the

 

changes in degenerative disorders of the nervous system. "

 

Dr. Roberts also says in this medical text: " Additional information

concerning the prevalence, clinical features and deranged

neurochemistry

 

of parkinsonism suggest other possible adverse effects by aspartame.

They

may involve presynaptic dopamine deficiency, and alteration of the

fine

balance between dopaminergic and cholinergic systems within the

brain. (An overbalance by the cholinergic system exists in

parkinsonism.)

 

* The incidence of parkinsonism among younger persons has increased

in

recent years.

* There is greater awareness that patients with Parkinson's disease

and

dementia may manifest some of the " specific " symptoms (such as

aphasia

and

visuospacial disturbances) present in Alzheimer's disease (Chui

l986,

Roberts l995b).

* Several authorities believe parkinsonism can be caused by

environmental

toxins that damage the substantia nigra, leading to " abiotrophy "

(the

premature and selective destruction) of functionally related neurons

(Calne l986). As a case in point, this disorder has occurred in

young

drug users exposed to illicit neurotoxic drugs, especially

l-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its

metabolic

product l-methyl-4-phenylpyridine (MPP).

* A comparable interrelationship is the amyotropic lateral

sclerosis-parkinsonism complex in Guam caused by ingesting one or

several

alanine-derived amino acids (Spencer l987). Such damage may remain

" subclinical " for several years or decades. "

 

Dr. Roberts goes on to say that other biochemical observations are

relevant.

 

* Aspartame can interfere with dopamine release in the brain.

(Chapter

XXIII).

* Whereas the intraperitoneal administration of phenylalanine to

rats in

 

doses from 200-500 mg/kg increases basal dopamine release, the

administration of 100 mg/kg reduces dopamine release (During l987).

* The methyl alcohol derived from aspartame (Chapter XXI) probably

plays

 

a role. McLean et al (l980) reported parkinsonism and other

neurological

 

abnormalities in two patients with methanol intoxication. Methyl

alcohol

 

appears to cause parkinsonism through postsynaptic dysfunction,

perhaps

by

interfering with dopamine reuptake at nerve terminals.

* Symmetrical necrosis and hemorrhage of the putamen have been found

in

a

number of patients with methanol intoxication. "

 

And so, Oprah, the experts have spoken. I believe if you would check

with

the other two victims you had on your show as well as the three

other

victims of Parkinson's Disease who once were on a show with Michael

Fox,

 

you might just find they are all aspartame users. I believe this to

be

the common denominator. I give you the challenge to find out. Well

call

it Oprah's Epidemiological Study!

 

You will find my original press release on Michael Fox on

www.dorway.com

 

and I discussed the issue on probably 70 international radio

programs. There was great response from people wanting to help

Michael

Fox, and most doctors who called suggested the use of

glyconutrients. I

would be surprised if some pharmaceutical company made a magic pill

as a

 

cure, especially with this neurotoxin still on the market and even

being

 

hidden in such things as artificial and natural flavors.

 

So many would like to help Michael Fox as well as the millions of

other

suffers of neurodegenerative diseases, that could be triggered by

this

deadly neurotoxin. And we are now taking case histories for class

action

 

starting with brain tumors, seizures, eye deterioration and

blindness

triggered by aspartame. An investigation could be the beginning of

help

for millions. And remember, Oprah they are now trying to get

approved

these model emergency bills where they can mandate vaccines, and

aspartame

as a chemical hypersensitization agent interacts with these as well,

and

 

can cause an even greater explosion of neurodegenerative diseases.

And

remember vaccines can trigger autism and aspartame triggers autism.

We

must protect our children.

 

Read below my signature of a recent case of someone diagnosed with

MS

who

got off aspartame. Imagine this happening throughout the world!

 

All my best,

Betty Martini, Founder, Mission Possible International, 9270 River

Club

Parkway, Duluth, Georgia 30097, 770 242-2599 www.dorway.com

 

 

 

 

Carnie1

Mon, 1 Apr 2002 21:18:08 EST

i am so thankful Multiple Sclerosis or Aspartame Disease

bett-

X-Mailer: AOL 7.0 for Windows US sub 121

 

Hello Betty....

Here I am just another victim of the diet soda syndrome.....In

October

of

2001 my sister became very ill...she had joint pain, stomach spasms,

headaches, blurred vision, slurred speech, memory loss etc....she

started

going to the doctors. Because of her stomach spasms, they diagnosed

her

with

crones disease, and she had no symptoms of it, but they felt they

had to

 

label her. She could barely walk, and great depression set in, her

menstral

cycle was way off and she often felt dizzy. She is a correction

officer

in

Cleveland Ohio, and a single mother....it took everything she had in

her

to

keep her job. Barely able to get out of bed, in early March 2002,

she

felt

she was dying, and decided to put her home, life insurance, and

custody

of

her younger children in her older daughters name. She wanted one

last

ho-oray, so she planned a trip down to Florida, (knowing she'd be

going

in a

wheelchair). She was due to arrive in Orlando on March 22, 2002 - on

Friday

March 15,2002 she was scheduled for a biopsy at the hospital in

which

her

daughter took her too. At this time the doctors had her on a

cocktail of

24

different prescription medications, including, steroids, oxycotin,

volume and

so on. So, on Tuesday March 19,2002 I called my sister to see how

things

 

went at the biopsy, she told me they ruled out crones disease, and

said

they

told her she had MS.....then it clicked...my friend had sent me an

email

on

nutra sweet thing, and I asked my sister if she drank diet soda. She

told me

she did drink diet Pepsi....and while I was on the phone with her,

she

was

getting ready to crack one open. I told her to stop drinking the

diet

soda

and any other stuff with aspartame in it....she called me the next

day....32

hours later....she was crying...I thought " OH NO " , what

happened...she

was

crying with joy...she was walking again...her stomach stopped having

spasms....she said she felt much much better...and has not had one

diet

soda

in 32 hours....I thought WOW...this is unreal....she took the email

to

her

doctors that day...he was amazed at her recovery, gave her a big

hug,

and

informed her that he was going to contact all his MS patients to

find

out

their diet. I live in FL, so when my sister got her on March

22,2002, we

 

went dancing....and she didn't need a wheel chair.....

Thank you so much for saving my sisters life.....God Bless all of

you....Marcy Nolan

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