Guest guest Posted October 26, 2008 Report Share Posted October 26, 2008 Tagamet has been around a long time as a cancer treatment. For who have Lewis antigens, it's supposed to double life-expectancy. Here's what LEF.org said about it. " Cimetidine The people writing about MJ mentioned Tagamet. I'm confused about whether cimitidine is a name for tagamet or even if it's the same thing as MJ. Too much buzzing around to track everything down! A Common Heartburn Remedy Complements Conventional Cancer TherapyBy Cynthia Haines, MDCimetidine Inhibits Tumor GrowthIn addition to its effects in boosting immunity, cimetidine may help to slow or halt cancer by inhibiting the growth of several types of tumors.8 For example, in a cell-culture study of four colorectal tumor cell lines and four melanoma cell lines, histamine stimulated cell proliferation in a dose-dependent manner, while cimetidine reversed this effect.8,23 In another study, cimetidine inhibited the growth of human pancreatic cancer cells that had been grafted into immunodeficient mice.24 These findings suggest possible applications for cimetidine in colorectal, skin, and pancreatic cancers. Scientists believe that cimetidine may prolong the survival of patients with various forms of cancer by inhibiting tumor-associated angiogenesis,25,26 the development of new blood vessels that tumors require to fuel their growth. In a 2005 report on cimetidine's effects on angiogenesis and tumor growth, cimetidine markedly reduced the growth (and production of new blood vessels needed to sustain the growth) of a grafted tumor in an animal model of colon cancer. These findings suggest that cimetidine suppresses tumor growth by inhibiting tumor-associated angiogenesis.25 Cimetidine may also fight cancer by promoting apoptosis (programmed cell death) in cancer cells. In a Chinese study from 2006, cimetidine induced apoptosis and halted cell division in human gastric cancer cells, leading the researchers to propose that cimetidine may have applications in treating gastric cancer.26 By shutting down the growth-stimulating effect of histamine, inhibiting angiogenesis, and promoting apoptosis, cimetidine thus appears to work via several mechanisms to arrest the growth of deadly tumors.Cimetidine Inhibits Cancer Cell Metastasis Most cancer deaths are caused not by primary tumors, but instead by metastases, or the secondary tumors that form when cells from the primary tumor spread to another location in the body. Cimetidine may prolong cancer survival by blocking the ability of cancer cells to metastasize to other locales in the body. Adhesion molecules play a crucial role in many biological processes, such as wound healing, immune response, and cancer metastasis. These adhesion molecules are expressed on the surface of endothelial cells that line the blood vessels, which facilitates their adherence to other cells. Adhesion molecules are intimately involved in the spread of cancer cells through the bloodstream to other locations where they will form secondary tumors. For example, when epithelial tumor cells enter blood vessels leading to the liver, they trigger the expression of an adhesion molecule called E-selectin in the liver blood vessel endothelium.27 This helps cancer cells form a secondary tumor in the liver. Several types of cancer cells use Lewis antigens—carbohydrate formations on cell surfaces that can activate an immune response—to bind with E-selectin in blood vessel walls. Cimetidine may help prevent cancer cells from migrating throughout the body and forming distant metastases by blocking the expression of E-selectin. When given to immunosuppressed mice with liver cancer, cimetidine successfully blocked tumor metastasis. Cimetidine appears to be unique in its ability to block cancer metastasis—similar H2-blocking drugs such as famotidine (Pepcid®) and ranitidine (Zantac®) did not produce a similar effect. Thus it appears that cimetidine's ability to block cancer metastasis is independent of its ability to bind the H2 histamine receptor.28Upon discovering cimetidine's ability to block cancer metastasis, researchers re-visited a study in which colorectal cancer patients were treated with cimetidine immediately before and after cancer surgery. They found cimetidine was particularly effective in enhancing survival for colorectal cancer patients with tumors expressing higher levels of two Lewis antigens.3 When the tumors were analyzed for Lewis antigen expression, patients who had tumors expressing Lewis antigens and who received cimetidine had a remarkable 10-year survival rate of 91%, compared to 34% for those not treated with cimetidine. In 2003, Japanese researchers published findings indicating that cimetidine blocked the adhesion of gastric, esophageal, and breast cancer cells (all of which expressed a specific Lewis antigen) to epithelial cells expressing E-selectin. They concluded that cimetidine may be effective in preventing metastasis of these cancers.29 Cimetidine thus holds great promise in protecting against metastasis, the process that paves the way for cancer's often-fatal spread throughout the body.ConclusionCimetidine's beneficial effects in helping to manage various cancers are well documented. For more than 20 years, scientists have accumulated evidence that this low-cost, readily available heartburn remedy fights cancer via several mechanisms of action, including blocking the immunosuppressive action of histamine, modulating the body's immune response, inhibiting angiogenesis, stimulating cancer cell death, and inhibiting cancer metastasis. Cimetidine has not yet been approved by the FDA for use in treating cancer, and it remains unclear how its effects may enhance or synergize with other cancer treatments. However, cimetidine's demonstrated effects suggest that it may markedly suppress the ability of certain cancers—particularly colorectal cancers—to grow and metastasize, even when used as a sole therapy. Further studies are needed to evaluate and document cimetidine's efficacy both alone and in concert with other cancer-fighting regimens. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 26, 2008 Report Share Posted October 26, 2008 Brand name is: Tagamet Generic name: Cimetidine Thanks for posting this article, I wish I knew the dose and how long one should take it? oleander soup , " Rhoda Mead " <hummingbird541 wrote: > > * Tagamet has been around a long time* as a cancer treatment. For who have > Lewis antigens, it's supposed to double life-expectancy. Here's what LEF.org > said about it. " Cimetidine The people writing about MJ mentioned Tagamet. I'm > confused about whether cimitidine is a name for tagamet or even if it's the > same thing as MJ. Too much buzzing around to track everything down! > > A Common Heartburn Remedy Complements Conventional Cancer Therapy > By Cynthia Haines, MD > Cimetidine Inhibits Tumor Growth > > In addition to its effects in boosting immunity, cimetidine may help to slow > or halt cancer by inhibiting the growth of several types of tumors.8 > > For example, in a cell-culture study of four colorectal tumor cell lines and > four melanoma cell lines, histamine stimulated cell proliferation in a > dose-dependent manner, while cimetidine reversed this effect.8,23 In another > study, cimetidine inhibited the growth of human pancreatic cancer cells that > had been grafted into immunodeficient mice.24 These findings suggest > possible applications for cimetidine in colorectal, skin, and pancreatic > cancers. > > Scientists believe that cimetidine may prolong the survival of patients with > various forms of cancer by inhibiting tumor-associated angiogenesis,25,26 > the development of new blood vessels that tumors require to fuel their > growth. In a 2005 report on cimetidine's effects on angiogenesis and tumor > growth, cimetidine markedly reduced the growth (and production of new blood > vessels needed to sustain the growth) of a grafted tumor in an animal model > of colon cancer. These findings suggest that cimetidine suppresses tumor > growth by inhibiting tumor-associated angiogenesis.25 > > Cimetidine may also fight cancer by promoting apoptosis (programmed cell > death) in cancer cells. In a Chinese study from 2006, cimetidine induced > apoptosis and halted cell division in human gastric cancer cells, leading > the researchers to propose that cimetidine may have applications in treating > gastric cancer.26 > > By shutting down the growth-stimulating effect of histamine, inhibiting > angiogenesis, and promoting apoptosis, cimetidine thus appears to work via > several mechanisms to arrest the growth of deadly tumors. > Cimetidine Inhibits Cancer Cell Metastasis > > Most cancer deaths are caused not by primary tumors, but instead by > metastases, or the secondary tumors that form when cells from the primary > tumor spread to another location in the body. Cimetidine may prolong cancer > survival by blocking the ability of cancer cells to metastasize to other > locales in the body. > > Adhesion molecules play a crucial role in many biological processes, such as > wound healing, immune response, and cancer metastasis. These adhesion > molecules are expressed on the surface of endothelial cells that line the > blood vessels, which facilitates their adherence to other cells. > > Adhesion molecules are intimately involved in the spread of cancer cells > through the bloodstream to other locations where they will form secondary > tumors. For example, when epithelial tumor cells enter blood vessels leading > to the liver, they trigger the expression of an adhesion molecule called > E-selectin in the liver blood vessel endothelium.27 This helps cancer cells > form a secondary tumor in the liver. > > Several types of cancer cells use Lewis antigens—carbohydrate formations on > cell surfaces that can activate an immune response—to bind with E-selectin > in blood vessel walls. Cimetidine may help prevent cancer cells from > migrating throughout the body and forming distant metastases by blocking the > expression of E-selectin. > > When given to immunosuppressed mice with liver cancer, cimetidine > successfully blocked tumor metastasis. Cimetidine appears to be unique in > its ability to block cancer metastasis—similar H2-blocking drugs such as > famotidine (Pepcid®) and ranitidine (Zantac®) did not produce a similar > effect. > > Thus it appears that cimetidine's ability to block cancer metastasis is > independent of its ability to bind the H2 histamine receptor.28 > > Upon discovering cimetidine's ability to block cancer metastasis, > researchers re-visited a study in which colorectal cancer patients were > treated with cimetidine immediately before and after cancer surgery. They > found cimetidine was particularly effective in enhancing survival for > colorectal cancer patients with tumors expressing higher levels of two Lewis > antigens.3 When the tumors were analyzed for Lewis antigen expression, > patients who had tumors expressing Lewis antigens and who received > cimetidine had a remarkable 10-year survival rate of 91%, compared to 34% > for those not treated with cimetidine. > > In 2003, Japanese researchers published findings indicating that cimetidine > blocked the adhesion of gastric, esophageal, and breast cancer cells (all of > which expressed a specific Lewis antigen) to epithelial cells expressing > E-selectin. They concluded that cimetidine may be effective in preventing > metastasis of these cancers.29 > > Cimetidine thus holds great promise in protecting against metastasis, the > process that paves the way for cancer's often-fatal spread throughout the > body. > Conclusion > > Cimetidine's beneficial effects in helping to manage various cancers are > well documented. For more than 20 years, scientists have accumulated > evidence that this low-cost, readily available heartburn remedy fights > cancer via several mechanisms of action, including blocking the > immunosuppressive action of histamine, modulating the body's immune > response, inhibiting angiogenesis, stimulating cancer cell death, and > inhibiting cancer metastasis. > > Cimetidine has not yet been approved by the FDA for use in treating cancer, > and it remains unclear how its effects may enhance or synergize with other > cancer treatments. However, cimetidine's demonstrated effects suggest that > it may markedly suppress the ability of certain cancers—particularly > colorectal cancers—to grow and metastasize, even when used as a sole > therapy. Further studies are needed to evaluate and document cimetidine's > efficacy both alone and in concert with other cancer-fighting regimens. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 28, 2008 Report Share Posted October 28, 2008 Mike,I went to the web site and it mentioned 800 mg, or 400 mg twice a day. I just took my first 400 mg . Hey this may safe my life. Nothing else seems to be stopping their growth.MaritzaMike V <mds9513oleander soup Sent: Sunday, October 26, 2008 12:12:12 AM Re: MJ or tagamet Brand name is: Tagamet Generic name: Cimetidine Thanks for posting this article, I wish I knew the dose and how long one should take it? oleander soup, "Rhoda Mead" <hummingbird541@ ...> wrote: > > * Tagamet has been around a long time* as a cancer treatment. For who have > Lewis antigens, it's supposed to double life-expectancy. Here's what LEF.org > said about it."Cimetidine The people writing about MJ mentioned Tagamet. I'm > confused about whether cimitidine is a name for tagamet or even if it's the > same thing as MJ. Too much buzzing around to track everything down! > > A Common Heartburn Remedy Complements Conventional Cancer Therapy > By Cynthia Haines, MD > Cimetidine Inhibits Tumor Growth > > In addition to its effects in boosting immunity, cimetidine may help to slow > or halt cancer by inhibiting the growth of several types of tumors.8 > > For example, in a cell-culture study of four colorectal tumor cell lines and > four melanoma cell lines, histamine stimulated cell proliferation in a > dose-dependent manner, while cimetidine reversed this effect.8,23 In another > study, cimetidine inhibited the growth of human pancreatic cancer cells that > had been grafted into immunodeficient mice.24 These findings suggest > possible applications for cimetidine in colorectal, skin, and pancreatic > cancers. > > Scientists believe that cimetidine may prolong the survival of patients with > various forms of cancer by inhibiting tumor-associated angiogenesis, 25,26 > the development of new blood vessels that tumors require to fuel their > growth. In a 2005 report on cimetidine's effects on angiogenesis and tumor > growth, cimetidine markedly reduced the growth (and production of new blood > vessels needed to sustain the growth) of a grafted tumor in an animal model > of colon cancer. These findings suggest that cimetidine suppresses tumor > growth by inhibiting tumor-associated angiogenesis. 25 > > Cimetidine may also fight cancer by promoting apoptosis (programmed cell > death) in cancer cells. In a Chinese study from 2006, cimetidine induced > apoptosis and halted cell division in human gastric cancer cells, leading > the researchers to propose that cimetidine may have applications in treating > gastric cancer.26 > > By shutting down the growth-stimulating effect of histamine, inhibiting > angiogenesis, and promoting apoptosis, cimetidine thus appears to work via > several mechanisms to arrest the growth of deadly tumors. > Cimetidine Inhibits Cancer Cell Metastasis > > Most cancer deaths are caused not by primary tumors, but instead by > metastases, or the secondary tumors that form when cells from the primary > tumor spread to another location in the body. Cimetidine may prolong cancer > survival by blocking the ability of cancer cells to metastasize to other > locales in the body. > > Adhesion molecules play a crucial role in many biological processes, such as > wound healing, immune response, and cancer metastasis.. These adhesion > molecules are expressed on the surface of endothelial cells that line the > blood vessels, which facilitates their adherence to other cells. > > Adhesion molecules are intimately involved in the spread of cancer cells > through the bloodstream to other locations where they will form secondary > tumors. For example, when epithelial tumor cells enter blood vessels leading > to the liver, they trigger the expression of an adhesion molecule called > E-selectin in the liver blood vessel endothelium. 27 This helps cancer cells > form a secondary tumor in the liver. > > Several types of cancer cells use Lewis antigens—carbohydrat e formations on > cell surfaces that can activate an immune response—to bind with E-selectin > in blood vessel walls. Cimetidine may help prevent cancer cells from > migrating throughout the body and forming distant metastases by blocking the > expression of E-selectin. > > When given to immunosuppressed mice with liver cancer, cimetidine > successfully blocked tumor metastasis. Cimetidine appears to be unique in > its ability to block cancer metastasis—similar H2-blocking drugs such as > famotidine (Pepcid®) and ranitidine (Zantac®) did not produce a similar > effect. > > Thus it appears that cimetidine's ability to block cancer metastasis is > independent of its ability to bind the H2 histamine receptor.28 > > Upon discovering cimetidine's ability to block cancer metastasis, > researchers re-visited a study in which colorectal cancer patients were > treated with cimetidine immediately before and after cancer surgery. They > found cimetidine was particularly effective in enhancing survival for > colorectal cancer patients with tumors expressing higher levels of two Lewis > antigens.3 When the tumors were analyzed for Lewis antigen expression, > patients who had tumors expressing Lewis antigens and who received > cimetidine had a remarkable 10-year survival rate of 91%, compared to 34% > for those not treated with cimetidine. > > In 2003, Japanese researchers published findings indicating that cimetidine > blocked the adhesion of gastric, esophageal, and breast cancer cells (all of > which expressed a specific Lewis antigen) to epithelial cells expressing > E-selectin. They concluded that cimetidine may be effective in preventing > metastasis of these cancers.29 > > Cimetidine thus holds great promise in protecting against metastasis, the > process that paves the way for cancer's often-fatal spread throughout the > body. > Conclusion > > Cimetidine's beneficial effects in helping to manage various cancers are > well documented. For more than 20 years, scientists have accumulated > evidence that this low-cost, readily available heartburn remedy fights > cancer via several mechanisms of action, including blocking the > immunosuppressive action of histamine, modulating the body's immune > response, inhibiting angiogenesis, stimulating cancer cell death, and > inhibiting cancer metastasis. > > Cimetidine has not yet been approved by the FDA for use in treating cancer, > and it remains unclear how its effects may enhance or synergize with other > cancer treatments. However, cimetidine's demonstrated effects suggest that > it may markedly suppress the ability of certain cancers—particularly > colorectal cancers—to grow and metastasize, even when used as a sole > therapy. Further studies are needed to evaluate and document cimetidine's > efficacy both alone and in concert with other cancer-fighting regimens. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 29, 2008 Report Share Posted October 29, 2008 You may want to add 4 100 mg doses of Vermox or generic name Mebendozole to it. You need to ask your Dr. for Vermox. oleander soup , Maritza Vlasaty <mvlasaty wrote: > > Mike, > I went to the web site and it mentioned 800 mg, or 400 mg twice a day. I just took my first 400 mg . Hey this may safe my life. Nothing else seems to be stopping their growth. > Maritza > > > > > ________________________________ > Mike V <mds9513 > oleander soup > Sunday, October 26, 2008 12:12:12 AM > Re: MJ or tagamet > > > Brand name is: Tagamet > Generic name: Cimetidine > > Thanks for posting this article, I wish I knew the dose and how long > one should take it? > > oleander soup, " Rhoda Mead " <hummingbird541@ ....> > wrote: > > > > * Tagamet has been around a long time* as a cancer treatment. For > who have > > Lewis antigens, it's supposed to double life-expectancy. Here's what > LEF.org > > said about it. " Cimetidine The people writing about MJ mentioned > Tagamet. I'm > > confused about whether cimitidine is a name for tagamet or even if > it's the > > same thing as MJ. Too much buzzing around to track everything down! > > > > A Common Heartburn Remedy Complements Conventional Cancer Therapy > > By Cynthia Haines, MD > > Cimetidine Inhibits Tumor Growth > > > > In addition to its effects in boosting immunity, cimetidine may help > to slow > > or halt cancer by inhibiting the growth of several types of tumors.8 > > > > For example, in a cell-culture study of four colorectal tumor cell > lines and > > four melanoma cell lines, histamine stimulated cell proliferation in a > > dose-dependent manner, while cimetidine reversed this effect.8,23 In > another > > study, cimetidine inhibited the growth of human pancreatic cancer > cells that > > had been grafted into immunodeficient mice.24 These findings suggest > > possible applications for cimetidine in colorectal, skin, and pancreatic > > cancers. > > > > Scientists believe that cimetidine may prolong the survival of > patients with > > various forms of cancer by inhibiting tumor-associated > angiogenesis, 25,26 > > the development of new blood vessels that tumors require to fuel their > > growth. In a 2005 report on cimetidine's effects on angiogenesis and > tumor > > growth, cimetidine markedly reduced the growth (and production of > new blood > > vessels needed to sustain the growth) of a grafted tumor in an > animal model > > of colon cancer. These findings suggest that cimetidine suppresses tumor > > growth by inhibiting tumor-associated angiogenesis. 25 > > > > Cimetidine may also fight cancer by promoting apoptosis (programmed cell > > death) in cancer cells. In a Chinese study from 2006, cimetidine induced > > apoptosis and halted cell division in human gastric cancer cells, > leading > > the researchers to propose that cimetidine may have applications in > treating > > gastric cancer.26 > > > > By shutting down the growth-stimulating effect of histamine, inhibiting > > angiogenesis, and promoting apoptosis, cimetidine thus appears to > work via > > several mechanisms to arrest the growth of deadly tumors. > > Cimetidine Inhibits Cancer Cell Metastasis > > > > Most cancer deaths are caused not by primary tumors, but instead by > > metastases, or the secondary tumors that form when cells from the > primary > > tumor spread to another location in the body. Cimetidine may prolong > cancer > > survival by blocking the ability of cancer cells to metastasize to other > > locales in the body. > > > > Adhesion molecules play a crucial role in many biological processes, > such as > > wound healing, immune response, and cancer metastasis. These adhesion > > molecules are expressed on the surface of endothelial cells that > line the > > blood vessels, which facilitates their adherence to other cells. > > > > Adhesion molecules are intimately involved in the spread of cancer cells > > through the bloodstream to other locations where they will form > secondary > > tumors. For example, when epithelial tumor cells enter blood vessels > leading > > to the liver, they trigger the expression of an adhesion molecule called > > E-selectin in the liver blood vessel endothelium. 27 This helps > cancer cells > > form a secondary tumor in the liver. > > > > Several types of cancer cells use Lewis antigens—carbohydrat e > formations on > > cell surfaces that can activate an immune response—to bind with > E-selectin > > in blood vessel walls. Cimetidine may help prevent cancer cells from > > migrating throughout the body and forming distant metastases by > blocking the > > expression of E-selectin. > > > > When given to immunosuppressed mice with liver cancer, cimetidine > > successfully blocked tumor metastasis. Cimetidine appears to be > unique in > > its ability to block cancer metastasis—similar H2-blocking drugs such as > > famotidine (Pepcid®) and ranitidine (Zantac®) did not produce a > similar > > effect. > > > > Thus it appears that cimetidine's ability to block cancer metastasis is > > independent of its ability to bind the H2 histamine receptor.28 > > > > Upon discovering cimetidine's ability to block cancer metastasis, > > researchers re-visited a study in which colorectal cancer patients were > > treated with cimetidine immediately before and after cancer surgery. > They > > found cimetidine was particularly effective in enhancing survival for > > colorectal cancer patients with tumors expressing higher levels of > two Lewis > > antigens.3 When the tumors were analyzed for Lewis antigen expression, > > patients who had tumors expressing Lewis antigens and who received > > cimetidine had a remarkable 10-year survival rate of 91%, compared > to 34% > > for those not treated with cimetidine. > > > > In 2003, Japanese researchers published findings indicating that > cimetidine > > blocked the adhesion of gastric, esophageal, and breast cancer cells > (all of > > which expressed a specific Lewis antigen) to epithelial cells expressing > > E-selectin. They concluded that cimetidine may be effective in > preventing > > metastasis of these cancers.29 > > > > Cimetidine thus holds great promise in protecting against > metastasis, the > > process that paves the way for cancer's often-fatal spread > throughout the > > body. > > Conclusion > > > > Cimetidine's beneficial effects in helping to manage various cancers are > > well documented. For more than 20 years, scientists have accumulated > > evidence that this low-cost, readily available heartburn remedy fights > > cancer via several mechanisms of action, including blocking the > > immunosuppressive action of histamine, modulating the body's immune > > response, inhibiting angiogenesis, stimulating cancer cell death, and > > inhibiting cancer metastasis. > > > > Cimetidine has not yet been approved by the FDA for use in treating > cancer, > > and it remains unclear how its effects may enhance or synergize with > other > > cancer treatments. However, cimetidine's demonstrated effects > suggest that > > it may markedly suppress the ability of certain cancers—particularly > > colorectal cancers—to grow and metastasize, even when used as a sole > > therapy. Further studies are needed to evaluate and document > cimetidine's > > efficacy both alone and in concert with other cancer-fighting regimens. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 29, 2008 Report Share Posted October 29, 2008 Would this be good for Ovarian Cancer as well. Is it a prescription or can you buy it over-the-counter? Hugs, Rose www.orangecountypropertyservices.com714.549-3519 Office/Fax 714.349-1200 Cell Be who you are and say what you feel, because those who mind don't matter and those who matter don't mind. ~Dr. Seuss oleander soup From: mvlasatyDate: Tue, 28 Oct 2008 15:01:16 -0700Re: Re: MJ or tagamet Mike,I went to the web site and it mentioned 800 mg, or 400 mg twice a day. I just took my first 400 mg . Hey this may safe my life. Nothing else seems to be stopping their growth.Maritza Mike V <mds9513 >oleander soup Sent: Sunday, October 26, 2008 12:12:12 AM Re: MJ or tagamet Brand name is: TagametGeneric name: CimetidineThanks for posting this article, I wish I knew the dose and how longone should take it?oleander soup, "Rhoda Mead" <hummingbird541@ ...>wrote:>> * Tagamet has been around a long time* as a cancer treatment. Forwho have> Lewis antigens, it's supposed to double life-expectancy. Here's whatLEF.org> said about it."Cimetidine The people writing about MJ mentionedTagamet. I'm> confused about whether cimitidine is a name for tagamet or even ifit's the> same thing as MJ. Too much buzzing around to track everything down!> > A Common Heartburn Remedy Complements Conventional Cancer Therapy> By Cynthia Haines, MD> Cimetidine Inhibits Tumor Growth> > In addition to its effects in boosting immunity, cimetidine may helpto slow> or halt cancer by inhibiting the growth of several types of tumors.8> > For example, in a cell-culture study of four colorectal tumor celllines and> four melanoma cell lines, histamine stimulated cell proliferation in a> dose-dependent manner, while cimetidine reversed this effect.8,23 Inanother> study, cimetidine inhibited the growth of human pancreatic cancercells that> had been grafted into immunodeficient mice.24 These findings suggest> possible applications for cimetidine in colorectal, skin, and pancreatic> cancers.> > Scientists believe that cimetidine may prolong the survival ofpatients with> various forms of cancer by inhibiting tumor-associatedangiogenesis, 25,26> the development of new blood vessels that tumors require to fuel their> growth. In a 2005 report on cimetidine's effects on angiogenesis andtumor> growth, cimetidine markedly reduced the growth (and production ofnew blood> vessels needed to sustain the growth) of a grafted tumor in ananimal model> of colon cancer. These findings suggest that cimetidine suppresses tumor> growth by inhibiting tumor-associated angiogenesis. 25> > Cimetidine may also fight cancer by promoting apoptosis (programmed cell> death) in cancer cells. In a Chinese study from 2006, cimetidine induced> apoptosis and halted cell division in human gastric cancer cells,leading> the researchers to propose that cimetidine may have applications intreating> gastric cancer.26> > By shutting down the growth-stimulating effect of histamine, inhibiting> angiogenesis, and promoting apoptosis, cimetidine thus appears towork via> several mechanisms to arrest the growth of deadly tumors.> Cimetidine Inhibits Cancer Cell Metastasis> > Most cancer deaths are caused not by primary tumors, but instead by> metastases, or the secondary tumors that form when cells from theprimary> tumor spread to another location in the body. Cimetidine may prolongcancer> survival by blocking the ability of cancer cells to metastasize to other> locales in the body.> > Adhesion molecules play a crucial role in many biological processes,such as> wound healing, immune response, and cancer metastasis.. These adhesion> molecules are expressed on the surface of endothelial cells thatline the> blood vessels, which facilitates their adherence to other cells.> > Adhesion molecules are intimately involved in the spread of cancer cells> through the bloodstream to other locations where they will formsecondary> tumors. For example, when epithelial tumor cells enter blood vesselsleading> to the liver, they trigger the expression of an adhesion molecule called> E-selectin in the liver blood vessel endothelium. 27 This helpscancer cells> form a secondary tumor in the liver.> > Several types of cancer cells use Lewis antigens—carbohydrat eformations on> cell surfaces that can activate an immune response—to bind withE-selectin> in blood vessel walls. Cimetidine may help prevent cancer cells from> migrating throughout the body and forming distant metastases byblocking the> expression of E-selectin.> > When given to immunosuppressed mice with liver cancer, cimetidine> successfully blocked tumor metastasis. Cimetidine appears to beunique in> its ability to block cancer metastasis—similar H2-blocking drugs such as> famotidine (Pepcid®) and ranitidine (Zantac®) did not produce asimilar> effect.> > Thus it appears that cimetidine's ability to block cancer metastasis is> independent of its ability to bind the H2 histamine receptor.28> > Upon discovering cimetidine's ability to block cancer metastasis,> researchers re-visited a study in which colorectal cancer patients were> treated with cimetidine immediately before and after cancer surgery.They> found cimetidine was particularly effective in enhancing survival for> colorectal cancer patients with tumors expressing higher levels oftwo Lewis> antigens.3 When the tumors were analyzed for Lewis antigen expression,> patients who had tumors expressing Lewis antigens and who received> cimetidine had a remarkable 10-year survival rate of 91%, comparedto 34%> for those not treated with cimetidine.> > In 2003, Japanese researchers published findings indicating thatcimetidine> blocked the adhesion of gastric, esophageal, and breast cancer cells(all of> which expressed a specific Lewis antigen) to epithelial cells expressing> E-selectin. They concluded that cimetidine may be effective inpreventing> metastasis of these cancers.29> > Cimetidine thus holds great promise in protecting againstmetastasis, the> process that paves the way for cancer's often-fatal spreadthroughout the> body.> Conclusion> > Cimetidine's beneficial effects in helping to manage various cancers are> well documented. For more than 20 years, scientists have accumulated> evidence that this low-cost, readily available heartburn remedy fights> cancer via several mechanisms of action, including blocking the> immunosuppressive action of histamine, modulating the body's immune> response, inhibiting angiogenesis, stimulating cancer cell death, and> inhibiting cancer metastasis.> > Cimetidine has not yet been approved by the FDA for use in treatingcancer,> and it remains unclear how its effects may enhance or synergize withother> cancer treatments. However, cimetidine's demonstrated effectssuggest that> it may markedly suppress the ability of certain cancers—particularly> colorectal cancers—to grow and metastasize, even when used as a sole> therapy. Further studies are needed to evaluate and documentcimetidine's> efficacy both alone and in concert with other cancer-fighting regimens.> You live life beyond your PC. So now Windows goes beyond your PC. See how Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 29, 2008 Report Share Posted October 29, 2008 Is tagmet over the counter?--- On Tue, 10/28/08, Gypsy Rose <gypsy___rose wrote: Gypsy Rose <gypsy___roseRE: Re: MJ or tagametoleander soup Date: Tuesday, October 28, 2008, 11:19 PM Would this be good for Ovarian Cancer as well. Is it a prescription or can you buy it over-the-counter? Hugs, Rose www.orangecountypro pertyservices. com714.549-3519 Office/Fax 714.349-1200 Cell Be who you are and say what you feel, because those who mind don't matter and those who matter don't mind. ~Dr. Seuss oleander soupmvlasaty Tue, 28 Oct 2008 15:01:16 -0700Re: Re: MJ or tagamet Mike,I went to the web site and it mentioned 800 mg, or 400 mg twice a day. I just took my first 400 mg . Hey this may safe my life. Nothing else seems to be stopping their growth.Maritza Mike V <mds9513 >oleander soupSunday, October 26, 2008 12:12:12 AM Re: MJ or tagamet Brand name is: TagametGeneric name: CimetidineThanks for posting this article, I wish I knew the dose and how longone should take it?oleander soup, "Rhoda Mead" <hummingbird541@ ...>wrote:>> * Tagamet has been around a long time* as a cancer treatment. Forwho have> Lewis antigens, it's supposed to double life-expectancy. Here's whatLEF.org> said about it."Cimetidine The people writing about MJ mentionedTagamet. I'm> confused about whether cimitidine is a name for tagamet or even ifit's the> same thing as MJ. Too much buzzing around to track everything down!> > A Common Heartburn Remedy Complements Conventional Cancer Therapy> By Cynthia Haines, MD> Cimetidine Inhibits Tumor Growth> > In addition to its effects in boosting immunity, cimetidine may helpto slow> or halt cancer by inhibiting the growth of several types of tumors.8> > For example, in a cell-culture study of four colorectal tumor celllines and> four melanoma cell lines, histamine stimulated cell proliferation in a> dose-dependent manner, while cimetidine reversed this effect.8,23 Inanother> study, cimetidine inhibited the growth of human pancreatic cancercells that> had been grafted into immunodeficient mice.24 These findings suggest> possible applications for cimetidine in colorectal, skin, and pancreatic> cancers.> > Scientists believe that cimetidine may prolong the survival ofpatients with> various forms of cancer by inhibiting tumor-associatedangiogenesis, 25,26> the development of new blood vessels that tumors require to fuel their> growth. In a 2005 report on cimetidine's effects on angiogenesis andtumor> growth, cimetidine markedly reduced the growth (and production ofnew blood> vessels needed to sustain the growth) of a grafted tumor in ananimal model> of colon cancer. These findings suggest that cimetidine suppresses tumor> growth by inhibiting tumor-associated angiogenesis. 25> > Cimetidine may also fight cancer by promoting apoptosis (programmed cell> death) in cancer cells. In a Chinese study from 2006, cimetidine induced> apoptosis and halted cell division in human gastric cancer cells,leading> the researchers to propose that cimetidine may have applications intreating> gastric cancer.26> > By shutting down the growth-stimulating effect of histamine, inhibiting> angiogenesis, and promoting apoptosis, cimetidine thus appears towork via> several mechanisms to arrest the growth of deadly tumors.> Cimetidine Inhibits Cancer Cell Metastasis> > Most cancer deaths are caused not by primary tumors, but instead by> metastases, or the secondary tumors that form when cells from theprimary> tumor spread to another location in the body. Cimetidine may prolongcancer> survival by blocking the ability of cancer cells to metastasize to other> locales in the body.> > Adhesion molecules play a crucial role in many biological processes,such as> wound healing, immune response, and cancer metastasis.. These adhesion> molecules are expressed on the surface of endothelial cells thatline the> blood vessels, which facilitates their adherence to other cells.> > Adhesion molecules are intimately involved in the spread of cancer cells> through the bloodstream to other locations where they will formsecondary> tumors. For example, when epithelial tumor cells enter blood vesselsleading> to the liver, they trigger the expression of an adhesion molecule called> E-selectin in the liver blood vessel endothelium. 27 This helpscancer cells> form a secondary tumor in the liver.> > Several types of cancer cells use Lewis antigens—carbohydrat eformations on> cell surfaces that can activate an immune response—to bind withE-selectin> in blood vessel walls. Cimetidine may help prevent cancer cells from> migrating throughout the body and forming distant metastases byblocking the> expression of E-selectin.> > When given to immunosuppressed mice with liver cancer, cimetidine> successfully blocked tumor metastasis. Cimetidine appears to beunique in> its ability to block cancer metastasis—similar H2-blocking drugs such as> famotidine (Pepcid®) and ranitidine (Zantac®) did not produce asimilar> effect.> > Thus it appears that cimetidine's ability to block cancer metastasis is> independent of its ability to bind the H2 histamine receptor.28> > Upon discovering cimetidine's ability to block cancer metastasis,> researchers re-visited a study in which colorectal cancer patients were> treated with cimetidine immediately before and after cancer surgery.They> found cimetidine was particularly effective in enhancing survival for> colorectal cancer patients with tumors expressing higher levels oftwo Lewis> antigens.3 When the tumors were analyzed for Lewis antigen expression,> patients who had tumors expressing Lewis antigens and who received> cimetidine had a remarkable 10-year survival rate of 91%, comparedto 34%> for those not treated with cimetidine.> > In 2003, Japanese researchers published findings indicating thatcimetidine> blocked the adhesion of gastric, esophageal, and breast cancer cells(all of> which expressed a specific Lewis antigen) to epithelial cells expressing> E-selectin. They concluded that cimetidine may be effective inpreventing> metastasis of these cancers.29> > Cimetidine thus holds great promise in protecting againstmetastasis, the> process that paves the way for cancer's often-fatal spreadthroughout the> body.> Conclusion> > Cimetidine's beneficial effects in helping to manage various cancers are> well documented. For more than 20 years, scientists have accumulated> evidence that this low-cost, readily available heartburn remedy fights> cancer via several mechanisms of action, including blocking the> immunosuppressive action of histamine, modulating the body's immune> response, inhibiting angiogenesis, stimulating cancer cell death, and> inhibiting cancer metastasis.> > Cimetidine has not yet been approved by the FDA for use in treatingcancer,> and it remains unclear how its effects may enhance or synergize withother> cancer treatments. However, cimetidine's demonstrated effectssuggest that> it may markedly suppress the ability of certain cancers—particularly> colorectal cancers—to grow and metastasize, even when used as a sole> therapy. Further studies are needed to evaluate and documentcimetidine's> efficacy both alone and in concert with other cancer-fighting regimens.> You live life beyond your PC. So now Windows goes beyond your PC. See how Quote Link to comment Share on other sites More sharing options...
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