Guest guest Posted April 6, 2002 Report Share Posted April 6, 2002 what about the sulphur and nux/puls as a detox? Good luck with this one - I either keep my eczema children for a long time or they disappear after the first visit!! Janice herbal remedies, jocelyne hemming <jh@g...> wrote: > What advice would you have for a child with horrible eczema after using > Chinese herbs, (he had only a couple of patches before). Now he is covered > with terrible eczema including face, some patches have got infected. He is 9 > years old, and has numerous allergies including peanuts. He is off dairy > produce too. He has an enormous appetite, which I am reading is due to the > fact that he is not absorbing his food properly. Does not have a bowel > motion everyday. > > I suggested a detox, which the parents are not keen on as he has such a > restricted diet already. I am sure there is problem around the bowel area > and liver, for a number of reasons. > > Any suggestions appreciated. > > Thanking you, > Jocelyne. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 6, 2002 Report Share Posted April 6, 2002 Jocelyne. I am a Chinese Style Herbalist and I am professionally - as well as - personally interested in your son's condition.-- I have a 4 year old who suffers mild re-occurring eczema. I have tried Chinese herbs, homeopathy (graphics (spelling!) , laser acupuncture, colloidal silver and seem to work but it keeps coming back as well as itching and constipation - with little appetite. could you tell me the name of the Chinese Herbs you used ? a few more common formulas used; -xiao feng san (eliminate wind powder) would seem to be indicated (weepy, itchy red skin lesions) - huang lian jie du tang (more for blood deficiency with some heat) - long dan xie gan tang ( eczema, herpes etc,) but not for long term as it damages the yin/ blood and may make the condition over time actually worse - gui zhi tang which can treat eczema when it from an imbalance of ying and wei qi but may make the condition worse if the cause is from interior heat - which may be in your case Of course there are numerous variations of the above. Chinese herbs do work but the diagnosis has to be correct. I would venture to say that the herbs used for our son were more for " superficial releasing " when " downward draining " formulas were indicated. I agree that he is not absorbing his food properly - which here would indicate Stomach Heat and also relate to the constipation (TCM) I could tell more if you could tell me the Chinese herbs and a little more of your son's history. Ed Kasper L.Ac., Acupuncturist & Herbs Chinese Herbs and Energy to maintain and restore health Santa Cruz, California & www.happyherbalist.com e-mail eddy Sat, 06 Apr 2002 05:53:26 +0100 jocelyne hemming <jh Eczema What advice would you have for a child with horrible eczema after using Chinese herbs, (he had only a couple of patches before). Now he is covered with terrible eczema including face, some patches have got infected. He is 9 years old, and has numerous allergies including peanuts. He is off dairy produce too. He has an enormous appetite, which I am reading is due to the fact that he is not absorbing his food properly. Does not have a bowel motion everyday. I suggested a detox, which the parents are not keen on as he has such a restricted diet already. I am sure there is problem around the bowel area and liver, for a number of reasons. Any suggestions appreciated. Thanking you, Jocelyne. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 7, 2002 Report Share Posted April 7, 2002 At 10:45 AM -0800 4/6/02, Ed Kasper wrote: > Jocelyne. I am a Chinese Style Herbalist and I am professionally - as well > as - personally interested in your son's condition.-- I have a 4 year old > who suffers mild re-occurring eczema. I have tried Chinese herbs, > homeopathy (graphics (spelling!) , laser acupuncture, colloidal silver and > seem to work but it keeps coming back as well as itching and constipation - > with little appetite. > I have found two things work. Sea water (the real stuff not made or a salt solution). The second was a material used for treating dandruff. Perhaps herbs which would help to remove skin faster might be a path. I am completely ignorant, so just take this as some thoughts which might inspire the more knowledgeable of you Zip The Dragonmaster Heaven on Earth dragonmasterzip He who rules truly serves and she who serves truly rules. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 23, 2004 Report Share Posted August 23, 2004 inner cleanse the gi tract and your eczema will improve So go an a lenghtly fast. drink diluted h202. take tinctures of vermifuge eat garlic intake less exiotoxins. change your diest to include natural foods that are not starchy or sweet and remember this inner cleanse can take up to seven years to see results --- forumtvm <forumtvm wrote: > Hi, > > Does any one have any suggestion on how to deal with > eczema? > > Pete > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 24, 2004 Report Share Posted August 24, 2004 , mike man <mgsboediitodpc> wrote: > inner cleanse the gi tract and your eczema will > improve > > So go an a lenghtly fast. > > drink diluted h202. > > take tinctures of vermifuge > > eat garlic > > intake less exiotoxins. > > change your diest to include natural foods that are > not starchy or sweet > > and remember this inner cleanse can take up to seven > years to see results > --- forumtvm <forumtvm> wrote: > > > Hi, > > > > Does any one have any suggestion on how to deal with > > eczema? > > > > Pete Make sure that H2O2 is Food Grade and not the store bought kind. Also you can do an H2O2 soak along with Epsom Salts and get alot of relief and possibly even a healing. You use the store bought for this unless you can afford the food grade. I use store bought and have had great success. You use one half cup of h2o2 and one half cup of epsom salts to start with and add to a tub of very warm water. Soak for at least 30 to 45 mins. Will also give you get up and go so don't do it too close to bed time. You can do this everyday if you want to. At first your skin will seem dry but after a few soaks you will notice how soft and silky you skin becomes. After 3 or 4 soaks use a cup of the h2o2 with the half cup of epsom salts. I now use one large 92 cent bottle from Wally World and love it!! This is a great way to pamper yourself. You can even put your hair down in it and it will not harm anyones color if they use it. This can be used for children also. Liz S.C. > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 25, 2004 Report Share Posted August 25, 2004 Hi Pete, I use total wellness and healthy products from Melaleuca, the wellness company. Below is one of my friend's testimonial which she sent out today. Some of the product names are included in her email. Regards, David "My son has horrible eczema. Before I joined mela we had tried every product on the market and nothing helped. Less then 2 weeks after swithching my home over his eczema he'd had for a year was GONE! It was awesome. Every little thing helps, getting all the toxic stuff that touches the skin out helps (laundry detergent, hand soap, carpet cleaner ect) and replacing with Mela products is a great idea, but I attribute most of his miracle to the GOLD bar. I wash him with the gold bar and follow up with Renew and his eczema stays at Bay. Usually with eczema, the more you wash, the more dried out and irritated the skin gets so they say to wash only occationally, I find the opposite is true now, and that the more often he is washed with the gold bar the better! Doesn't dry his skin out at all! Hope that helps! Please let me know if you have any questions! I also wanted to add that one of the naturals shampoos (melaleuca oil one is better for this!) should be used on the person with excema as they are the most gentle and when you rince the hair it touches other parts of the body so you don't want anything else touching the skin that might irritate it!" ~Jessica Middleton --- forumtvm <forumtvm wrote:> Hi,> > Does any one have any suggestion on how to deal with> eczema?> > Pete> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 23, 2006 Report Share Posted January 23, 2006 Although the FDA here are not recommending these creams for hosptial paitents they have nevertheless trialled them for 2 years on children and infants! With homeopathy, eczema is one of the easiest things to cure. Jane The agent pimecrolimus (Elidel) is a topical immunosuppressant calcineurin inhibitor and is currently being very heavily marketed for use in children with eczema. It is more effective than placebo, but there are no good studies comparing its efficacy and safety with the previous standard treatment of weak topical steroids. There have been many concerns voiced regarding its potential for unintended immunosuppression, and possible carcinogenicity. There are good biological reasons to predict such effects and some animal & human evidence to suggest the risks of both are not insignificant. In the last couple of months there have been 2 studies published claiming evidence for safety and lack of effect on immune function (as shown by immune response to vaccination). These studies are small, short-term and uncontrolled. They must be interpreted with caution. Also, the Division of Pediatric Drug Development of the Federal Drug Administration (FDA) has made recommendations that pimecrolimus (Elidel) and tacrolimis (Protopic) carry a warning of these safety concerns. My view: these agents are probably effective in the treatment of mild atopic eczema but there remain very significant concerns about safety issues, which only very large, and long-term studies will resolve. With the current level of knowledge, I might prescribe them for very short-term use in older children but would not use them for widespread or prolonged use in younger babies. I know some dermatologists hold different views. The RCH Drug Usage Committee has not approved these agents for use in our hospital patients. The studies mentioned, plus the FDA recommendation are detailed below. MIKE Long-term control of atopic dermatitis with pimecrolimus cream 1% in infants and young children: A two-year study J Am Acad Dermatol 2005;52:240-6Kim A. Papp, MD, PhD, FRCP,a Thomas Werfel, MD,b Regina Fo¨lster-Holst, MD,c Jean-Paul Ortonne, MD,d Paul C. Potter, MD,e Yves de Prost, MD,f Miles J. Davidson, MD,g Nathalie Barbier, Hans-Peter Goertz, MPH,h and Carle Paul, MDh Waterloo, Canada; Hannover and Kiel, Germany; Nice and Paris, France; Cape Town, South Africa; Dronfield, United Kingdom; and Basel, Switzerland Objective and methods: The safety and efficacy of treatment with pimecrolimus cream 1% was evaluated for up to 2 years in infants and young children with atopic dermatitis. Ninety-one patients participated in a 1-year, open-label extension to a 1-year double-blind study. Of these, 76 received pimecrolimus 2 years. Pimecrolimus was applied twice daily at the first signs or symptoms of the disease until clearance. Outcome measures included the incidence of adverse events and the Eczema Area and Severity Index (EASI). Results: No patient discontinued because of adverse events. The incidence of systemic and skin infections did not increase over time. Over the 2-year period, 2 patients experienced an episode of clinically diagnosed eczema herpeticum. In patients receiving pimecrolimus for 2 years, the mean decrease in EASI score from baseline was 68.7% at 3 months and 70.8% at 24 months. Conclusion: Treatment with pimecrolimus cream 1% for up to 2 years was well tolerated and resulted a marked and sustained improvement of atopic dermatitis. Long-term treatment of atopic dermatitis with pimecrolimus cream 1% in infants does not interfere with the development of protective antibodies after vaccination J Am Acad Dermatol 2005;52:240-6 Objective We investigated whether treatment of atopic dermatitis with pimecrolimus cream 1% in infants affects the development of a normal antibody response to vaccinations. Methods In all, 91 patients participated in a 1-year, open-label extension to a 1-year double-blind study: 76 used pimecrolimus twice daily at the first signs or symptoms of the disease until clearance for 2 years and 15 only in the second year. Serum concentrations of antibodies against tetanus, diphtheria, measles, and rubella were measured at months 18 and 24. Results The seropositivity rates of 93.6% for tetanus, 88.6% for diphtheria, 88.5% for measles, and 84.4% for rubella were comparable with those reported in literature. Seropositivity was not significantly affected by the use of pimecrolimus at the time of vaccinations (± 28 days). Conclusions Treatment of atopic dermatitis with pimecrolimus cream 1% in early childhood does not appear to interfere with the development of a normal immune response to vaccinations. Federal Drug Administration - Division of Pediatric Drug Development. Recommendations for Tacrolimus and Pimecrolimus The Division of Pediatric Drug Development (DPDD) recommends a boxed warning for both Protopic and Elidel. This recommendation is based on the totality of scientific information available thus far which includes animal carcinogenicity signal both in mice and monkeys, post-marketing tumor-related adverse event reports coupled with the increased absorption in atopic dermatitis resulting in greater systemic exposure. The evidence raises serious safety concerns in children regarding the potential for carcinogenicity in humans treated with these agents. These products are being widely used to treat atopic dermatitis, a non-life threatening disease, and heavily advertised for use in young children without appreciation by parents and physicians regarding the potential for carcinogenic risk. We believe regulatory action is needed at this time since a definitive answer to the carcinogenic risk of these products will not be known for years and the difficulty of designing a clinical study that will provide a definitive answer to this question For background, Protopic Ointment (tacrolimus) and Elidel Cream (pimecrolimus) are indicated for the short-term and intermittent long-term treatment of atopic dermatitis in patients >2 years of age who are either unresponsive or intolerant of alternative, conventional therapies or in whom the use of these therapies is deemed inadvisable due to potential risks. Protopic and Elidel are calcineurin inhibitors and immunosuppressants. Although their exact mechanism of action is not known, they exert direct immunosuppressive effects as evidenced by inhibition of T cell activation and inhibition of various interleukins and interferon gamma. Although these products are applied topically, they may be systemically absorbed. Detectable drug levels in the blood are more frequently observed in children than in adults. This higher systemic drug exposure in children may be related to their greater body surface area to mass ratio. Scientific evidence for systemic immunosuppression from topical application of these products is available in both humans and animals. In animals, the carcinogenicity signal is strong, consistent, and dependent on dose and treatment duration. In mice, lymphoma formation was reported with application of Protopic and with Elidel dissolved in ethanol, at 26x and 47x MRHD (maximum recommended human dose) based on AUC comparisons, respectively. In addition, the median time to skin tumor formation was decreased in hairless mice following chronic Protopic administration with concurrent exposure to UV irradiation. Furthermore, the latency time to lymphoma formation was shortened to 8 weeks after administration of Elidel in ethanol to mice at a dose of 179-217x MRHD based on AUC comparisons. In humans, post-marketing tumor-related adverse events related to these products continues to be reported. Since marketing approval (12/08/00 for Protopic and 12/13/01 for Elidel), 7 cases of lymphoma have been reported, four with Protopic and three with Elidel. Five of these 7 cases occurred in adults; one, in a 2 year old child; and one in a patient of unreported age. Duration of use is known in 5/7 cases (several weeks, 5 months, 6 months in 2 and 1 ½ years in another); occurrence was reported at the site of drug application in one. In addition, there is one case of cutaneous Kaposis sarcoma which developed at the site of Protopic application and that became metastatic in an HIV positive adult. To date, 6 cases of skin cancer (of which three were recurrences) have been reported in adults, five with Protopic and one with Elidel. In 4/6 cases, the latency time to skin cancer was reported: 1-2 weeks, 3-4 weeks, 8 weeks and 3 months. Of these 6 cases, there was a history of atrophic lichen sclerosis in two cases and occurrence at the site of drug application in 2 different cases. Of note, the incidence of skin papillomas, a risk factor for precancerous lesions and cancer, was reported pre-marketing in children treated with Elidel (in the Adverse Reactions section of the Elidel package insert, the incidence of skin papillomas in the 6-week pediatric study was 0.4% (1/267) with Elidel and 0 (0/136) with vehicle control; in the 1-year safety study, it was 3.3% (9/272) with Elidel and <1% of 75 patients treated with vehicle control ). Post-marketing, 2 cases of papilloma have been reported with Elidel, one in a child and one in an adult. Additional post-marketing tumor-related cases in children include one case each of facial tumor, type unspecified, with Elidel cream, Sezarys syndrome after three years of Protopic use, hepatoblastoma after one year of Protopic use and one case of sudden increase in size of metastatic angiosarcoma after three months of Protopic use. Additional supportive evidence of immunosuppression in pediatric patients includes the increased incidence of specific infections that occurred with these products compared to vehicle alone in the pediatric clinical trials conducted pre-marketing. These results are reported in the Pediatric Use and Adverse Reactions sections of the Package Inserts. Of the cases of infections reported post marketing in pediatric patients, the most significant case was that of an 8-month old male who developed eczema herpeticum with pseudomonas sepsis and subsequent cardiac arrest. Protopic ointment was applied over his entire body for 6 months. Of note, the serum tacrolimus level was 3.5 ng/ml two weeks after Protopic had been discontinued. The patient survived. It is known that oral or parenteral administration of immunosuppressant drugs is associated with an increased incidence of infection and cancer, particularly lymphoma. Tacrolimus injection (Prograf), cyclosporine and azathioprine, all of which include an indication for prevention of organ transplant rejection, contain a boxed warning. Although a systemic preparation of tacrolimus, Prograf, is available, there currently is no marketed systemic preparation of Elidel. Of note, a recent non-human primate study conducted with an oral formulation of Elidel which is under development, demonstrated the occurrence of lymphoma in all dose groups studied, including the lowest dose which represented 30x MRHD for the topical product. Therefore, a NOEL for lymphoma was not established in this study. Of further concern, lymphoma was reported in one of four recovery animals despite discontinuation of treatment. In this study, lymphoma was associated with a latent infection by an Epstein Barr related virus which is the same mechanism described in immunosuppressed humans following transplantation. In addition, three of nine monkeys developed concurrent leukemia. The immunosuppressive effects of these topical products in animals, manifested primarily as lymphoma formation, are strong, consistent and compelling. The biological relevance of these animal findings to humans exposed to these drugs cannot be excluded. In addition, immunosuppression is the proposed mechanism of action of Protopic and Elidel. These products are indicated for the intermittent but chronic treatment of a non life-threatening condition, atopic dermatitis. The abraded skin characteristic of atopic dermatitis increases systemic absorption of these drugs and, as noted above, children have higher systemic blood levels of these drugs compared to adults, and, thus, greater systemic drug exposure. Given that these topical products may be applied chronically in a young child over an extensive surface area of abraded skin, there is potential for significant cumulative drug exposure. As demonstrated in the animal carcinogenicity studies, the development of lymphoma was dependent on cumulative drug exposure, being a function of dose and treatment duration. The increasing number of post-marketing tumor-related adverse events is concerning because they too, like the animal carcinogenicity findings and the known carcinogenicity potential with systemic administration of these drugs to humans, relate to the mechanism of action of this drug class, i.e., immunosuppression. CFR 201.57 provides the Agency with the legal and regulatory authority to require a boxed warning based on serious animal toxicity in the absence of clinical data. FDA has previously exercised this authority. Such was the case for Forteo (teriparatide injection) and Flagyl (metronidazole tablets). Therefore, there is precedent. A boxed warning is the most effective labeling tool FDA has to convey a potential safety signal or risk. It is also recommended that the PPI for these products inform patients/parents/caregivers of the potential cancer risk based on the animal carcinogenicity findings and the post-marketing adverse events. The use of these products continues to increase, including use in the very young, although they are not approved in patients less than 2 years of age. For example, from June, 2003-May, 2004, the number of prescriptions dispensed for Protopic, increased by 16% and for Elidel, by 46%, compared to the previous year. In this same time period, patients aged 1-2 years, accounted for 8% and 13% of Protopic and Elidel prescriptions, respectively. The increasing use may be related to aggressive and inappropriate advertising with portrayal of these products as safer than steroids and the implication that they can be used as first-line therapy and for unlimited periods of time. A presentation entitled: ELIDEL Redefining Successful Therapy & A Blockbuster in the Making!was delivered by Kurt Graves, Chief Marketing Officer, Novartis, on their 2003 R & D day. Included in this presentation were plans to develop the drug for flare prevention among other indications (e.g., chronic hand dermatitis) and to expand usage to infants with atopic dermatitis. In conclusion, based on the scientific information available to date which raises serious safety concerns regarding the potential for carcinogenicity of these agents in humans, the Division of Pediatric Drug Development recommends that a boxed warning be included in the Package Inserts for Protopic and Elidel. Mike A/Prof Mike South, Royal Children's Hospital, Parkville, Victoria 3052, Australia ---------- ---- Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 14, 2007 Report Share Posted December 14, 2007 Sir I am certain that application of high quality almond or sesame oil over the entire body followed by application of besan or chick pea flour paste left to dry and then rubbed off will help you immensely along with milk thistle tea twice daily to help support the liver. _______ I have been suffering from eczema for a year now,...... I would be grateful if someone knowledgeable from this group could help me out, no allopathy medicine is helping me. Any Ayurveda medicine is there for this. Quote Link to comment Share on other sites More sharing options...
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