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oh my....medline abstract on vitamin K and bone formation

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(Mindy's note: Interesting how the scientists discovered that the

vitamin K had to be administered in as pure a form as possible, rather

than hydrogenated...isn't it?? =) )

 

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=1\

1722960 & dopt=Abstract

 

" Effects of a hydrogenated form of vitamin K on bone formation and

resorption.

 

Booth SL, Lichtenstein AH, O'Brien-Morse M, McKeown NM, Wood RJ,

Saltzman E, Gundberg CM.

 

Jean Mayer US Department of Agriculture, Human Nutrition Research Center

on Aging at Tufts University, Boston, MA 02111, USA.

sbooth

 

BACKGROUND: Hydrogenation of vegetable oils affects blood lipid and

lipoprotein concentrations. However, little is known about the effects

of hydrogenation on other components, such as vitamin K. Low

phylloquinone (vitamin K1) intake is a potential risk factor for bone

fracture, although the mechanisms of this are unknown. OBJECTIVE: The

objective was to compare the biological effects of phylloquinone and its

hydrogenated form, dihydrophylloquinone, on vitamin K status and markers

of bone formation and resorption. DESIGN: In a randomized crossover

study in a metabolic unit, 15 young adults were fed a

phylloquinone-restricted diet (10 microg/d) for 15 d followed by 10 d of

repletion (200 microg/d) with either phylloquinone or

dihydrophylloquinone. RESULTS: There was an increase and subsequent

decrease in measures of bone formation (P = 0.002) and resorption (P =

0.08) after dietary phylloquinone restriction and repletion,

respectively. In comparison with phylloquinone, dihydrophylloquinone was

less absorbed and had no measurable biological effect on measures of

bone formation and resorption. CONCLUSION: Hydrogenation of plant oils

appears to decrease the absorption and biological effect of vitamin K in

bone.

 

PMID: 11722960 [PubMed - in process] "

 

Mindy

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Nick Grant wrote:

 

> What do you mean - Vit K is hydrogenated? My daughter has 10mg each day of

> Konakion....is this hydrogenated as well?

 

Tracy,

Some cream forms have been hydrogenated... however, Konakion is a synthetic

form of Vitamin K (phytomenadione), sorry to say. :( Here's what DrumLib has

to say about synthetic Vitamin K: " I would avoid the synthetic forms because

they can be toxic -- especially in children. Menadione is a provitamin K that

combines with sulfhydryl groups in membranes and can cause jaundice, hemolysis,

and kernicterus. Don't take anything but natural vitamin K. "

http://www.drumlib.com/dn/vi.htm#Vitamin%20K

 

To that I add, you can buy 10mg of naturally occuring Vitamin K at your local

health food store. I think. *scratching head* I'm trying to remember what

their highest amount was...maybe their highest was only 1mg per pill :/ Look

for " Phylloquinone " or " Phytonadione "

 

Mindy

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Well if you can find 10mg of Vitamin K ( natural) I would be very surprised.

How does it come? Tablet or powder?

 

I would love to get her on the natural, but the amounts that she has, I have

yet to find it in mg - only mcg - too small an amount. The oral doesn't

seem to be making any difference to her bleeding noses, so I will stop it

again anyway.

 

Thanks for that info

 

Tracy

 

> To that I add, you can buy 10mg of naturally occuring Vitamin K at your

local

> health food store. I think. *scratching head* I'm trying to remember

what

> their highest amount was...maybe their highest was only 1mg per pill :/

Look

> for " Phylloquinone " or " Phytonadione "

>

> Mindy

>

>

>

> Getting well is done one step at a time, day by day, building health

> and well being.

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Nick Grant wrote:

 

> Well if you can find 10mg of Vitamin K ( natural) I would be very surprised.

> How does it come? Tablet or powder?

>

 

Yeah, I think it was only 1mg of Vitamin K per pill, so the cost would be

prohibitive... :/

 

What other problems does your daughter have? Does she bruise easily? I have

been bruising easily, but I started taking the Vitamin K and more importantly,

*reduced* significantly the addition to aspirin to my bodybuilding stack, and

have come to think that it was bothering my liver... It's helped a little bit -

at least now there are no more new bruises, and the current bruises are healing

and fading. I also got some liver-cleansing tea from the health food

store...who knows if that'll actually work!!

 

> I would love to get her on the natural, but the amounts that she has, I have

> yet to find it in mg - only mcg - too small an amount. The oral doesn't

> seem to be making any difference to her bleeding noses, so I will stop it

> again anyway.

 

Alfalfa may help. Not sure about doses. Type in " alfalfa " and " coagulant " or

" alfalfa " and " liver " in google.com and you'll get an eyeful!

 

Mindy

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