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Avascular necrosis and medical astrology Avascular necrosis-- Avascular necrosis (also osteonecrosis, bone infarction, aseptic necrosis, ischemic bone necrosis,and AVN) is a disease where there is cellular death (necrosis) of bone components due to interruption of the blood supply. Without blood, the bone tissue dies and the bone collapses. If avascular necrosis involves the bones of a joint, it often leads to destruction of the joint articular surfaces. (see Osteochondritis dissecans). Although it can happen in any bone, osteonecrosis most commonly affects the ends (epiphysis) of the femur, the bone extending from the knee joint to the hip joint. Other common sites include the upper arm bone, knees, shoulders, and ankles. The disease may affect just one bone, more than one bone at the same time, or more than one bone at different times. Osteonecrosis of the jaw (ONJ) is a rare condition that has been linked to the use of biphosphonate medications. ONJ has different causes and treatments than osteonecrosis found in other parts of the skeleton. The amount of disability that results from osteonecrosis depends on what part of the bone is affected, how large an area is involved, and how effectively the bone rebuilds itself. Normally, bone continuously breaks down and rebuilds—old bone is replaced with new bone. This process, which takes place after an injury as well as during normal growth, keeps the skeleton strong and helps it to maintain a balance of minerals. In the course of osteonecrosis, however, the healing process is usually ineffective and the bone tissues break down faster than the body can repair them. If left untreated, the disease progresses, the bone collapses, and the joint surface breaks down, leading to pain and arthritis. What Causes Osteonecrosis? Osteonecrosis is caused by impaired blood supply to the bone, but it is not always clear what causes that impairment. Osteonecrosis often occurs in people with certain medical conditions or risk factors (such as high-dose corticosteroid use or excessive alcohol intake). However, it also affects people with no health problems and for no known reason. Following are some potential causes of osteonecrosis and other health conditions associated with its development. Steroid Medications Aside from injury, one of the most common causes of osteonecrosis is the use of corticosteroid medications such as prednisone. Corticosteroids are commonly used to treat inflammatory diseases such as systemic lupus erythematosus, rheumatoid arthritis, inflammatory bowel disease, severe asthma, and vasculitis. Studies suggest that long-term use of oral or intravenous corticosteroids is associated with nontraumatic osteonecrosis. Patients should discuss concerns about steroid use with their doctor. Doctors are not sure exactly why the use of corticosteroids sometimes leads to osteonecrosis. They speculate that the drugs may interfere with the body’s ability to break down fatty substances called lipids. These substances then build up in and clog the blood vessels, causing them to narrow and to reduce the amount of blood that gets to the bone. Some studies suggest that corticosteroid-related osteonecrosis is more severe and more likely to affect both hips (when occurring in the hip) than osteonecrosis resulting from other causes. Alcohol Use Excessive alcohol use is another common cause of osteonecrosis. People who drink alcohol in excess can develop fatty substances that may block blood vessels, causing a decreased blood supply to the bones. Injury When a fracture, a dislocation, or some other joint injury occurs, the blood vessels may be damaged. This can interfere with the blood circulation to the bone and lead to trauma-related osteonecrosis. In fact, studies suggest that hip dislocation and hip fractures are major risk factors for osteonecrosis. Increased pressure within the bone may be another cause of osteonecrosis. When there is too much pressure within the bone, the blood vessels narrow, making it hard for them to deliver enough blood to the bone cells. The cause of increased pressure is not fully understood. Other Risk Factors Other risk factors for osteonecrosis include radiation therapy, chemotherapy, and organ transplantation (particularly kidney transplantation). Osteonecrosis is also associated with a number of medical conditions, including cancer, systemic lupus erythematosus (SLE), blood disorders such as sickle cell disease, HIV infection, Gaucher’s disease, Caisson disease, gout, vasculitis, osteoarthritis, and osteoporosis. Western astrology prospective-- SYSTEM FUNCTION ASSOCIATED ORGANS INTERACTION WITH THE NERVOUS SYSTEM Skeletal System The skeletal system makes up the framework of the body and allows us to move when our muscles contract. It stores minerals (e.g. calcium, phosphorous) and releases them into the body when they are needed. The skeletal system also protects internal organs and produces blood cells. Bones (e.g., skull, vertebrae) ASSOCIATED PLANET: SATURN Bones provide calcium that is essential for the proper functioning of the nervous system. The skull protects the brain from injury. The vertebrae protect the spinal cord from injury. Sensory receptors in joints between bones send signals about body position to the brain. The brain regulates the position of bones by controlling muscles. Cardiovascular System The cardiovascular system delivers oxygen, hormones, nutrients and white blood cells around the body by pumping blood, and it removes waste products. Heart, blood vessels ASSOCIATED PLANET: SUN: Heart Endothelial cells maintain the blood-brain barrier. Baroreceptors send information to the brain about blood pressure. Cerebrospinal fluid drains into the venous blood supply. The brain regulates heart rate and blood pressure. Muscular System Different types of muscles enable motion, generate heat to maintain body temperature, move food through digestive tract and contract the heart. Muscles (smooth, skeletal and cardiac muscles) Planet -Mars. Receptors in muscles provide the brain with information about body position and movement. The brain controls the contraction of skeletal muscle. The nervous system regulates heart rate and the speed at which food moves through the digestive tract. The seven dhatus and systems as per ayurvedic astrology. Jupiter Fat Saturn Veins Mars Bone Marrow Sun Bones Moon Blood Mercury Skin Venus Seminal Energy Sun The Bone System Moon The Circulatory System Mars The Muscular System Mercury The Veins Venus The Reproductive System Jupiter The Digestive System Saturn The Excretory System RELATION OF PLANETS AND DISEASES Mars, Mercury, Moon Rheumatism, musculo skeletal Saturn, Sun Problems and bone diseases Mars, Mercury Digestive diseases, diabetes Saturn, Ketu Diseases of the nervous system Mercury, Mars, Ketu Psychological diseases, including hysteria Mars, Saturn, Rahu Skin diseases Saturn, Mars, Moon,Venus, Mercury, Jupiter Urinary and gynaecological problems Saturn, Mars Dental problems Saturn, Mars Ear nose, and throat problems Saturn, Mars Blood-related problems Coming to the disease Avascular necrosis let us examine the chart. Noticable points -- Saturn as sixth lord is present in ascendant, it is in maran karaka sthaan,very malefic and disease promoting,It aspects sun and venus as dispositor of sun ,it establishes a relation with lagna lord Sun,remember as illustrated above Saturn +Sun both indicate bone problems ,since the sign of action is libra it indicates lion and hips area ,where femur is.Sun as lagna lord is debilitated and under malefic influence of saturn and debilated mars.Retrograde jupiter in star of ardra( rahu) also aspects sun and venus conjunction ,Jupiter is lord of 8th house as well.Moon as lord of 12th and incapacitation and hospitalisation is under the seventh aspect of retrograde 8th lord jupiter ,moon in Sagittarius means trouble to thighs and hip area.Mercury is dispositor of mars placed in 12th house means health trouble related to mars significations .Saturn and uranus connection through an aspect is also present often indicator of chronic disorder. Lord of 64 th navamsa is moon the 12th lord here,and 22nd drekana is jupiter the 8th lord.The native was operated for corrective surgery around 1 year ago though the surgery was successful the recovery is very little . DBA at the time of surgery was Mars ,Venus ,saturn. Mars as MD lord is star pushya of saturn the 6th lord.Mars is significator of surgery as well.