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Psoriasis--is an immune-mediated disease that affects the skin. It is typically a lifelong condition. There is currently no cure, but various treatments can help to control the symptoms. Psoriasis occurs when the immune system mistakes a normal skin cell for a pathogen, and sends out faulty signals that cause overproduction of new skin cells. It is not contagious. Psoriasis has been linked to an increased risk of stroke, and treating high blood lipid levels may lead to improvement. There are five types of psoriasis: plaque, gutate, inverse, pustular, and erythrodermic. The most common form, plaque psoriasis, is commonly seen as red and white hues of scaly patches appearing on the top first layer of the epidermis (skin). Some patients, though, have no dermatological signs or symptoms. The name psoriasis (ψωρίασις) is from the Greek language, meaning roughly "itching condition" (psora "itch" + -sis "action, condition"). In plaque psoriasis, skin rapidly accumulates at these sites, which gives it a silvery-white appearance. Plaques frequently occur on the skin of the elbows and knees, but can affect any area, including the scalp, palms of hands and soles of feet, and genitals. In contrast to eczema, psoriasis is more likely to be found on the outer side of the joint. The disorder is a chronic recurring condition that varies in severity from minor localized patches to complete body coverage. Fingernails and toenails are frequently affected (psoriatic nail dystrophy) and can be seen as an isolated sign. Psoriasis can also cause inflammation of the joints, which is known as psoriatic arthritis. Between 10% and 30% of all people with psoriasis also have psoriatic arthritis. Diseases due to afflictions of the Karakas of houses. If the Karaka of a house is in the 6th house Associated with Saturn and Rahu, the native suffers From a chronic disease indicated by the house in Question. Lord of sixth is conjunct the 8th lord ,saturn and venus and aspected by retrograde jupiter in 11th house and rahu from first house ,so we have afflicted sixth lord mercury ,8th lord sun ,5th and 10th lord venus and lord of ascendant or lagna saturn all under the malefic aspect of rahu and functional malefic jupiter the planet of expansion.,here jupiter is in nakshatra of saturn thus in control of saturn.While saturn is in nakshatra of 8th lord sun.There are two grah yudhas in the horoscope Rahu defeats Mars in planetary war and venus defeats saturn the lagan lord here rendering it weak to pep up the immune system.More so lors of 64rh navamsa is Mercury and 22nd drekana Sun.The native was first diagonalised with Psoriasis in 1997 in MD of rahu and AD-Jupiter then in 2000 it was a full blown disease the dasha sequence was Rahu-Saturn. Conclusion- We have seen the role of mercury,saturn ,jupiter and rahu in manifesting the disease . What causes diseases ? Saturn and Rahu are slow moving planets and are said to be huge in form (symbolically). Therefore according to principles of symbology, the diseases caused by them are long lasting and chronic. Astrological causes---- Mercury - As it rules over immune system and skin. Saturn - For all chronic diseases and skin significator. Sixth lord,8th lord and 11th lord ( because 11 th is 6th from 6th and significator of expansion) Jupiter for expansion as karak for 11th house. Rahu and ketu for sudden onset . Mercury represents memory and intelligence. Weak nervous system, skin problems, allergies, hay fever, Obsessive Compulsive Disorders, confusion, weak mind, lack of memory are some of the effect of malefic mercury. Saturn itself is considered a planet of diseases, sorrows and old age. Rheumatic pains, nervous disorders, arthritis, bones problems, fractures, paralysis, osteoporosis, sever depression and old age related diseases etc. are the indicator of malefic Saturn. Mercury Cold and dry. Relates to the nervous system and to nervous activity. Jupiter Expansive, nourishing, warm and moist, sanguine. Relates to the blood circulation, liver and fat metabolism and cellular nutrition. Saturn Contracting, slowing, binding, restricting, hardening, devitalising, cold and dry, melancholic. Sign-- Libra ,Aquarius for skin. As per ayurveda a skin disease happens due to imbalance of Fire and water element and are mostly pitta in dosha.