mediterranean diet

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Effect of an Indo-Mediterranean diet on progression of coronary artery disease

in high risk patients (Indo-Mediterranean Diet Heart Study): a randomised

single-blind trial

 

 

 

The Lancet (Volume 360, Number 9344, 09 November 2002: 1455-61)

 

Ram B Singh, Gal Dubnov, Mohammad A Niaz, Saraswati Ghosh, Reema Singh, Shanti S

Rastogi, Orly Manor, Daniel Pella, Elliot M Berry

 

 

 

November 9, 2002

 

 

 

" The rapid emergence of coronary artery disease (CAD) in south Asian people is

not explained by conventional risk factors. In view of cardioprotective effects

of a Mediterranean style diet rich in -linolenic acid, (the authors) assessed

the benefits of this diet for patients at high risk of CAD.(The authors) did a

randomised, single-blind trial in 1000 patients with angina pectoris, myocardial

infarction, or surrogate risk factors for CAD. 499 patients were allocated to a

diet rich in whole grains, fruits, vegetables, walnuts, and almonds. 501

controls consumed a local diet similar to the step I National Cholesterol

Education Program (NCEP) prudent diet (which permits up to 300 mg of cholesterol

per day). The intervention group consumed more fruits, vegetables, legumes,

walnuts, and almonds than did controls... (They) noted a significant reduction

in serum cholesterol concentration and other risk factors in both groups, but

especially in the intervention diet group. In the treatment group, patients with

pre-existing CAD had significantly greater benefits compared with such patients

in the control group.

 

Original Science Article:

http://www.thelancet.com/journal/vol360/iss9344/full/llan.360.9344.original_rese\

arch.23027.1