Guest guest Posted November 13, 2002 Report Share Posted November 13, 2002 By Maggie Fox Health and Science Correspondent 11-12-2 WASHINGTON (Reuters) - It may not be what you eat, but how you cook it, that affects whether food causes heart disease, diabetes and other conditions, researchers in the United States reported on Monday. Ê A new study shows that cooking at high temperatures -- frying, grilling and= even microwaving -- creates compounds that are associated with disease when they are found in the body. Ê Foods cooked by low-temperature methods such as boiling and steaming do not contain as many of these compounds, the team at the Mount Sinai School of Medicine in New York found. Ê While the findings do not discount the benefits of a healthy diet low in fa= t and sugar, they may help explain why some people who stick to such a diet continue to suffer from heart disease and diabetes, Dr. Helen Vlassara, who= led the study, said in a telephone interview. Ê The culprits are called advanced glycation end products or AGEs for short. = They are made by the interactions of sugars, fats, and proteins and form quickly when food is cooked at high temperatures. Ê " These are substances that are forming spontaneously in our body from glucose reactions, " Vlassara said. " The higher the glucose is, the higher t= he products will be. Diabetics have a lot more, and they are highly toxic. " Ê Writing in the Proceedings of the National Academy of Sciences, Vlassara and colleagues said AGEs can irritate cells, causing them to produce proteins that trigger inflammation, such as C-reactive protein. Ê " We tend always to cook our food under high heat. And because most foods consist of proteins, lipids and sugars, when we heat them under high heat for a long time, those reactions are accelerated. We end up absorbing those= , " she said. Ê TASTY AND BROWN, BUT NOT HEALTHY? Ê This kind of cooking produces tasty foods, Vlassara said. " They make the food taste good, or make it look good -- by browning it, " she said. Ê Animal products rich in fat are the worst culprits, she said. Ê Her team studied 24 diabetes patients, giving them identical diets that differed only in how the food was prepared. Ê " The diets that we tested and gave to patients in this report are those tha= t are recommended for diabetics, " Vlassara, a specialist in diabetes, said. Ê But where one group got grilled tuna, another got poached tuna, for example= .. The poached tuna would presumably be lower in AGEs as it was cooked at lower temperatures. Ê There were clear differences in the blood of the patients, although it was = too soon to tell whether there were health benefits, Vlassara said. Ê Those eating the high AGE diet had more AGEs in their blood, and also had higher levels of inflammatory chemicals such as tumor necrosis factor and C-reactive protein. Ê These inflammatory chemicals are linked with the progression of heart disease and the damage caused by diabetes -- such as blindness, nerve damage, and damage to organs such as the kidney. Ê In other studies on animals, Vlassara said a low-AGE diet helped prevent th= e development of type-I diabetes, caused when the body mistakenly attacks and destroys the pancreatic cells that make insulin. Ê Vlassara said she did not believe her findings related to the discovery thi= s year that some fried and baked foods contain high levels of chemicals calle= d acrylamides, which can cause cancer in animals. Quote Link to comment Share on other sites More sharing options...
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