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Plan to create human-cow embryos

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wow, a true cowboy then...........

 

 

>heartwerk <jo.heartwork

>Nov 6, 2006 11:55 PM

>

> Plan to create human-cow embryos

>

>UK scientists have applied for permission to create embryos by fusing

>human DNA with cow eggs.

>

>Researchers from Newcastle University and Kings College, London, have

>asked the Human Fertilisation and Embryology Authority for a three-

>year licence.

>

>The hybrid human-bovine embryos would be used for stem cell research

>and would not be allowed to develop for more than a few days.

>

>But critics say it is unethical and potentially dangerous.

>

>Liberal Democrat MP Dr Evan Harris - a member of the Commons Science

>and Technology Select Committee - said: " If human benefit can be

>derived by perfecting therapeutic cloning techniques or from research

>into subsequently-derived stem cells, then it would actually be

>immoral to prevent it just because of a 'yuck' factor. "

>

>Stem cell research is one of the most promising areas of medical

>science.

>

> You may begin to undermine the whole distinction between humans

>animals and humans

>

>Calum MacKellar

>Stem cells are the body's master cells and five-day-old embryos are

>packed with them - each with the potential to turn into any tissue in

>the body.

>

>It is this ability which scientists want to harness to treat diseases

>such as Parkinson's Disease, strokes and Alzheimer's Disease.

>

>To do that, they need to have access to thousands of embryos for

>research.

>

>Short supply

>

>The problem is that human eggs for research are in short supply and

>to obtain them women have to undergo surgery.

>

>That is why scientists want to use cows' eggs as a substitute.

>

>They would insert human DNA into a cow's egg which has had its

>genetic material removed, and then create an embryo by the same

>technique that produced Dolly the Sheep.

>

>The resulting embryo would be 99.9% human; the only bovine element

>would be DNA outside the nucleus of the cell.

>

>It would, though, technically be a chimera - part-human, part-animal.

>

>The aim would be to extract stem cells from the embryo when it is six

>days old, before destroying it.

>

> If human benefit can be derived by perfecting therapeutic cloning

>techniques or from research into subsequently-derived stem cells,

>then it would actually be immoral to prevent it just because of

>a 'yuck' factor

>

>Dr Evan Harris

>

>The quality and the viability of stem cells would then be checked to

>see if the technique had worked.

>

>The scientists also plan to examine the way the cells are

>reprogrammed after fusion to see if there are useful processes they

>could replicate in the laboratory.

>

>Lead researcher Dr Lyle Armstrong said: " If we can learn from the egg

>cell how to make embryonic stem cells without having to use an animal

>egg at all then some day we may be able to cure diseases such as

>Parkinson's disease, or better still some of the age-related diseases

>which are creating such a burden on society. "

>

>Dr Stephen Minger, from King's College London, said: " The current

>state of the technology is such that literally hundreds of human

>ooctyes (eggs) from young women will be required to generate a single

>human embryonic stem cell line.

>

> " Therefore we consider it more appropriate to use non-human oocytes

>from livestock as a surrogate.

>

> " We feel that the development of disease-specific human embryonic

>stem cell lines from individuals suffering from genetic forms of

>neurodegenerative disorders will stimulate both basic research and

>the development of new medicines to treat these horrific brain

>diseases. "

>

>'Undermining humanity'

>

>Professor Robin Lovell-Badge, head of developmental genetics,

>National Institute for Medical Research, said: " This is a very

>rational step: to learn what you can using animal eggs, which are

>readily obtainable, before moving on to valuable human eggs when or

>if this becomes necessary. "

>

>

>

>

>

>

>To send an email to -

>

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