India and Antacids -- Warning: Side Effects May Be Severe

[Guest guest]

Published on Thursday, May 12, 2005 b the Providence Journal (Rhode Island)

India and Antacids -- Warning: Side Effects May Be Severe

by Stan Cox

 

SALINA, Kansas -- THE UNITED STATES has become the number-one market for India's

pharmaceutical exports, with purchases reaching $250 million in 2003. But by the

time those medicines are swallowed in Chicago or Shreveport, their side effects

are already felt by villagers downstream or downwind from the drug factories.

 

India's pharmaceutical industry is concentrated in a few areas, one of the most

prominent -- and notorious -- being near the town of Patancheru, in the state of

Andhra Pradesh.

 

Over the past two decades, a growing chain of industrial estates has turned this

20-mile stretch of countryside into an ecological sacrifice zone. The estates'

dominant plants make bulk drugs, technically known as " active pharmaceutical

ingredients " : raw materials for pills, capsules, etc. Bulk-drug market

competition is fierce, so corner cutting on waste treatment is rampant.

 

Given the ecological and human costs of India's drug industry, I propose that

the U.S. Food and Drug Administration add warnings to labels on imported drugs.

For example: " Side effects -- including drowsiness, skin rashes,

gastrointestinal distress, neurological disorders, cardiovascular problems

and/or cancer -- may be encountered by those living near the site of manufacture

of this drug. "

 

A 2004 survey by Greenpeace India compared villages and found high rates of

these and other ailments where the water is shared with drug plants. Two

universities are studying health problems in the area.

 

The mere smell of the villages' water is enough to make you gag. Pollutant

concentrations in the area's streams and lakes range from 12 to 100 times those

in an unpolluted lake just outside the contaminated zone, according to the 2004

report of a committee appointed by the state's High Court.

 

In accordance with court orders, drug companies are paying to have safe water

piped into affected villages for drinking and cooking. But the polluted water is

still used for other purposes in the home and on the farm.

 

This brings us to another labeling suggestion: " Warning: This product may

disrupt food production in certain areas. "

 

Thousands of acres of farmland around Patancheru lie uncultivated during the dry

season, because groundwater has become unfit for irrigation. The court committee

sampled 48 wells in the area and found 81 percent of them polluted beyond an

international standard for irrigation water.

 

How about this warning?: " Consumption of this antacid may induce headache,

coughing and/or nausea downwind from where it was produced. "

 

Despite repeated government crackdowns, some factories still pollute the

Patancheru area's air with sulfurous mercaptan compounds that smell like rotten

fish (ironically, in the production of stomach antacids).

 

Finally: " Some patients will experience sharp pangs of remorse when they learn

more about the conditions under which this medication was produced. "

 

The court committee visited 40 " pollution potential " companies in the industrial

estates. Of those, 30 were producing drugs or drug ingredients, and only 5 were

fully complying with Patancheru's lenient pollution laws.

 

For effluent at new drug plants in the United States, the Environmental

Protection Agency sets strict limits on at least 34 chemical compounds, from

acetone to xylene. But in Patancheru, where normally only the total quantity of

pollutants is tracked, there's almost no information on specific toxic

compounds. That's serious, because some of the drug industry's solvents,

byproducts, and ingredients can harm people even at low concentrations.

 

When it comes to the cost of patented prescription drugs in the United States,

the sky's the limit. But in the global bulk-drug market, low cost is the name of

the game -- and India's people and landscape are the losers.

 

Meanwhile, are you wondering if the U.S. medical establishment is aware of the

global pharmaceutical trade's side effects? Ask your doctor.

 

Stan Cox, senior research scientist at the Land Institute, in Salina, Kans.,

lived in India for seven years and recently spent three months there. He wrote

this for the institute's Prairie Writers Circle.

 

 

 

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