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High Folic Acid Intake Linked to Mental Decline

>

> High intakes of folic acid result in a faster rate of mental

decline,

> according to a new study.

>

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

cmd=Retrieve & db=pubmed & dopt=Ab

stract & list_uids=15824266

>

> Those in the top fifth of folic acid consumption, i.e., more than

700

> micrograms in a day, had twice the rate of mental decline over six

> years than those who with the lowest folate intake. Rates of decline

> were also faster among people who got more than 400 micrograms of

> folate in the form of supplements, and among those whose folate

> intake from food was nearly 400 micrograms.

>

> One possible explanation for this finding could be a undetected

> vitamin B-12 deficiency. The study found that a high B-12 intake was

> associated with slower mental decline among the oldest study

> participants. Those who consumed 20 micrograms of B-12 through

> supplements daily had a 25 percent lower decline than those who got

> the recommended level of B-12 for adults (i.e., 2.4 micrograms ).

> Many know about supplementing with folic acid, but perhaps most

don't

> supplement with B-12. Good mental functioning requires cholesterol

> in the brain. So, perhaps excessive folic acid intake adversely

> affects brain chemistry. Nevertheless, it appears that high intakes

> of folic acid used to control high homocysteine levels should only

be

> done on a temporary basis.

>

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