Situation Analysis: Stirred Heterogeneous Batch Biofilm Bioreactor Analysis

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Situation Analysis: Stirred Heterogeneous

Batch Biofilm Bioreactor Analysis

 

 

The batch bioreactor is the most extensively

used in the biotechnology industry, yet this class of bioreactor as

compared to the continuous operating reactors has several limitations.

These include heterogeneity of reaction fluid in the batch reactor when

large scale batch reactor designs are simply performed by the

traditional scale-up methods, the death of cells during the emptying

and recharging of reactors for next run cycles, the need to support of

two consecutive reactions in same batch reactor and inability to use

high conversion but pathogenic microbes in batch reactors among other

considerations. However, heterogeneous batch bioreactor, carefully and

creatively designed and in which the microbes immobilization beads are

in suspended flow dynamics impressed on the reaction fluid by stirring

essentially, overcomes all the limitations.

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