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R: R: herb-drug thyroxine

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Hi, Hugo! About the same problem of Melissa o., I searched some article

about Huang Qin , Scutellaria baicalensis (is in Tian Wang Bu Xin Tang)

since scutellaria has some activity similar to Melissa, and is Cold and

Bitter. Scutellaria (The Lancet, Vol.350. November 29,1997, pag.1598-1599)

has the largest quantity in Melatonin known (av. 7.11 micrograms/gram) while

St.John's worth (flowers) reaches only aver. 4.39 micrograms/gram. I found

this in Cochrane database (keyword were, firstly, Hang qin and then

baicalein):

Some dietary flavonoids inhibit thyroperoxidase and hepatic deiodinase

activity, indicating that these compounds could be classified as

anti-thyroid agents. In this study, we evaluated the in vitro effect of

various flavonoids on thyroid type 1 iodothyronine deiodinase activity (D1).

D1 activity was measured in murine thyroid microsome fractions by the

release of 125I from 125I-reverse T3. D1 activity was significantly

inhibited by all the flavonoids tested; however, the inhibitory potencies on

thyroid D1 activity differed greatly among them. A 50% inhibition of D1

activity (IC(50)) was obtained at 11 microM baicalein, 13 microM quercetin,

17 microM catechin, 55 microM morin, 68 microM rutin, 70 microM fisetin, 72

microM kaempferol and 77 microM biochanin A. Our data reinforce the concept

that dietary flavonoids might behave as antithyroid agents, and possibly

their chronic consumption could alter thyroid function. (Ferreira

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;> IA; Carvalho

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');> DP, Inhibition of thyroid type 1 deiodinase activity by flavonoids. in

:Food

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Chemical Toxicology: An International Journal Published For The British

Industrial Biological Research Association [Food Chem Toxicol] 2002 Jul;

Vol. 40 (7), pp. 913-7.

 

So it could be possible an inhibition of the gland, of course, after long

periods in treatment, with Huang Qin, too. (Of course it could be very

useful in terating hyperthyroidism.......) :-)

 

 

 

 

_____

 

Da: Chinese Medicine

Chinese Medicine Per conto di Hugo

Ramiro

Inviato: giovedì 24 settembre 2009 21.27

A: Chinese Medicine

Oggetto: Re: R: herb-drug thyroxine

 

 

 

 

Hi Gabriele!

 

Interestingly Melissa Officinalis, which inhibits thyroid gland function, is

cold in nature.

 

:)

 

Hugo

 

________________________________

Hugo Ramiro

http://middlemedici <http://middlemedicine.wordpress.com> ne.wordpress.com

http://www.middleme <http://www.middlemedicine.org> dicine.org

 

________________________________

<saudelligabriele@

<saudelligabriele%40tiscali.it> tiscali.it>

Traditional_ <Chinese Medicine%40>

Chinese_Medicine

Thursday, 24 September, 2009 14:16:12

R: herb-drug thyroxine

 

Melissa officinalis, since an active pharmaceutical ingredient binds itself

on the TSH receptor in the gland. In such a way that it can inhibits the

gland function (pseudo-hypothyroid ism). Of course, after a long period in

taking Melissa o.

 

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