Guest guest Posted October 1, 2005 Report Share Posted October 1, 2005 Ladies, and Gents, We may one day in the not too distant future put aside the semantics of whether Essential Oils are medicine or not as they may be one of the few remaining, effective defenses left in the medicinal store front. So, step it up, learn their properties and applications with regard to Influenza. INFLUENZA VIRUSES, DRUG RESISTANCE ********************************** A ProMED-mail post <http://www.promedmail.org> ProMED-mail is a program of the International Society for Infectious Diseases <http://www.isid.org> Sponsored in part by Elsevier, publisher of Tropical Infectious Diseases, 2nd Edition <http://intl.elsevierhealth.com/catalogue/title.cfm?ISBN=044306668X> [1] Fri 30 Sep 2005 Cat Bachman <catbachman Source: Reuters UK, Fri 30 Sep 2005 [edited] <http://today.reuters.co.uk/news/newsArticle.aspx?type=scienceNews & storyID=2005-\ 09-30T114757Z_01_YUE042474_RTRIDST_0_SCIENCE-BIRDFLU-TAMIFLU-DC.XML> A strain [isolate?] of the H5N1 avian influenza virus that may unleash the next global flu pandemic is showing resistance to Tamiflu, the antiviral drug that countries around the world are now stockpiling to fend off the looming threat. Experts in Hong Kong said on Friday [30 Sep 2005] that the human H5N1 strain [isolate?] which surfaced in northern Viet Nam this year had proved to be resistant to Tamiflu, a powerful antiviral drug. They urged drug manufacturers to make more effective versions of Relenza, another antiviral that is also known to be effective in battling the much-feared H5N1. Relenza is inhaled [whereas Tamiflu is taken orally]. " There are now resistant H5N1 strains [isolates] appearing, and we can't totally rely on one drug (Tamiflu), " William Chui, honorary associate professor with the Department of Pharmacology at the Queen Mary Hospital in Hong Kong, told Reuters. Chui was referring to the Tamiflu-resistant strain of H5N1 [avian influenza] in Viet Nam. Chui also said general viral resistance to Tamiflu was growing in Japan, where doctors habitually prescribe the drug to fight common influenza. Switzerland's Roche Holdings AG makes Tamiflu, known generically as oseltamivir, and GalaxoSmithKline makes Relenza, or zanamivir. " Manufacturers should think about producing an injectable form of Relenza because resistance to Tamiflu has been seen in Japan and Viet Nam. Also with injections, high doses can be given where necessary and onset time is a lot faster, " Chui said. Drugs that are administered intravenously can be better absorbed in patients who have stomach and acidity problems, another expert said. " We don't have to worry about absorption, injections take drugs right in. But if the patient takes them orally, maybe some amounts won't be absorbed or some may be destroyed by stomach acids, " said pharmacist Raymond Mak at Queen Mary Hospital. Intravenous Relenza would also ensure faster onset, which would be critical in patients who are seriously ill. " Orally taken drugs take 3-4 hours to reach maximum blood concentration and 3-4 hours is very critical in severe cases. But injectable Relenza takes only 30 minutes to reach maximum blood concentration, this is a huge difference, " Chui said. With an intravenous antiviral, doctors can also vary the doses. While the H5N1 virus is now mostly passed directly from bird to human, health experts have warned that it is just a matter of time before it mutates into a form that is easily transmissible between people. When that happens, it may result in as many as 150 million human deaths. 2 reports in The Lancet this month said that resistance to anti-influenza drugs was growing worldwide. In places such as China, drug resistance exceeded 70 percent, suggesting that drugs like amantadine and rimantadine will probably no longer be effective for treatment or as a preventive in a pandemic outbreak of flu, the reports said. [byline: Tan Ee Lyn] -- Cat Bachman <catbachman ****** [2] Fri 30 Sep 2005 ProMED-mail <promed Source: The Lancet 2005; 366:1175-1181, Fri 30 Sep 2005 [edited] <http://www.thelancet.com/journals/lancet/article/PIIS0140673605673382 /abstract> Cause for Concern: Incidence of Adamantane Resistance among Influenza A (H3N2) Viruses Isolated Worldwide from 1994 to 2005 --------------- Adamantanes have been used to treat influenza A virus infections for many years. Studies have shown a low incidence of resistance to these drugs among circulating influenza viruses; however, their use is rising worldwide and drug resistance has been reported among influenza A (H5N1) viruses isolated from poultry and human beings in Asia. We sought to assess adamantane resistance among influenza A viruses isolated during the past decade from countries participating in WHO's global influenza surveillance network. We analysed data for influenza field isolates that were obtained worldwide and submitted to the WHO Collaborating Center for Influenza at the US Centers for Disease Control and Prevention between 1 Oct 1994, and 31 Mar 2005. We used pyrosequencing, confirmatory sequence analysis, and phenotypic testing to detect drug resistance among circulating influenza A H3N2 (n=6524), H1N1 (n=589), and H1N2 (n=83) viruses. More than 7000 influenza A field isolates were screened for specific amino acid substitutions in the M2 gene known to confer drug resistance. During the decade of surveillance, a significant increase in drug resistance was noted, from 0.4 percent in 1994-1995 to 12.3 percent in 2003-2004. This increase in the proportion of resistant viruses was weighted heavily by those obtained from Asia, with 61 percent of resistant viruses isolated since 2003 being from people in Asia. Our data raise concerns about the appropriate use of adamantanes and draw attention to the importance of tracking the emergence and spread of drug-resistant influenza A viruses. (Authors: Rick A Bright a, Marie-jo Medina a, Xiyan Xu a, Gilda Perez-Oronoz a, Teresa R Wallis a, Xiaohong M Davis a, Laura Povinelli b, Nancy J Cox a, and Alexander I Klimov a: the Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Influenza Branch, Atlanta, GA, USA b: Wisconsin State Laboratory of Hygiene, Madison, WI, USA). -- ProMED-mail <promed [Resistance to amantadine and rimantadine has been recorded previously, but the high frequency of resistant virus where these drugs have been used extensively over a considerable period suggests that their future usefulness will be limited. Resistance to the neuraminidase inhibitors oseltamivir and zanamivir has generally not been observed. The recent appearance of a Tamiflu-resistant avian H5N1 influenza virus in Viet Nam is an alarming development. - Mod.CP] [see also: Avian influenza, human - East Asia (120): Viet Nam 20050901.2589 Avian influenza, poultry - China: antiviral treatment 20050621.1740 2004 ---- Avian influenza - Eastern Asia (93): WHO statement 20040716.1935 Avian influenza A (H5N1) virus, human vaccine prospects 20040125.0300 Avian influenza A (H5N1) virus, drug resistance 20040125.02982001 ---- Influenza virus, neuraminidase inhibitor resistance (02) 20010928.2372 Influenza virus, neuraminidase inhibitor resistance 20010926.2350] ................................cp/pg/dk --- Carol Ann <saffireskyes wrote: > --- rastapoodle <mccoy wrote: > > > , " Mother > > Earth's Apothecary " > > Hi Michelle: > > > 2. The other information you share - " medicinal > > grade " , no refrigeration - sound suspiciously > like > > > the incorrect information used > > by a local con artist who sells his oils to his > > students. He's the only person I've ever heard use > the term medicinal grade and no refrigeration. I > visited one of his franchise stores here and the > poor > > girl was mortified to learn she had bunk rose oil > > (orangey FO stuff) > > Hi Anya, > > I didn't realize to what extent his reputation was > so > mired within the industry...and that it is so > widespread. In some regards, it is indeed, a small > world. > > Wasn't there recently some Hulaballo about about a > gal who supposedly coined the word " hydrosol " as > being > of her origination? > > Yes, " medicinal grade " is the mantra hype of the > person in question. Medicine is the implication. > And > to some extent, I must agree in concept. Oils are > very much medicine. To be used as any other > medicine. > As are the herbs, flowers, roots they are derived > from > before distillation. Aromatherapy and Herbs have > always been considered medicine, from which many of > the Pharma's originate and are marketed. They were > used as medicine before the luxuries such as > shampoos, > scrubs, toileteries, etc they are primarily > associated > with today. Fortunately, they are once again being > taken seriously. > > That they are used for " medicinal " purposes is a > fact > that few would dispute. That they are not officially > categorized as medicine by the FDA is a boon, for > their use would surely fall prey to scrutiny, > dis/approval and limitation. We could easily find > them > on the CODEX list as well. > > That " grades " or " quality " of oils per se are > different, diluted, etc is a given. Some oils are > superior to others by virture of their procurement, > origin and processing. We can tip too toe around > semantics all day with regard to whether they are > " medicinal " > > > and terrible stock. She had invested $10k and had > to > > sue him. > > I am very familiar with that situation and the > parties > involved. As usual, there is more to the " story " > than > was disclosed to you. > > > IMO, he's a local version of Gary Young, without > the > > scandals. He advocates women squirt a pipette of > >undiluted lavender oil into their vaginas > > for infections down there! Just a horrible con > > artist, and dangerous, too. > > I cannot and will not attest to his moral character > or > integrity, one way or another. Nor would I wish to > do > so. But, for clarification, (I can see how > information > has a way or morphing into sensationalism) what IS > recommended by a local Urologist, whose medical > practice is Holistic is NOT that pipette of Lavender > be squirted into the vagina, but that few drops be > applied to a panty lining. This information was > incorporated into the teaching ciriculum and passed > on > to students as ancellary information because of the > apparent effectiveness in dealing with UT > infections. > > > > But I'm rambling. Research, and also hundreds of > > years of experience with essential oils has shown > that they need to be stored tightly-capped, in dark > bottles, away from light and heat. > > Not only from light and heat, but from disruptive > " vibrations " as well. > > > Yow. I just saw CAM. Oy, you are working with him. > > Double yow. I'll bet he insists you buy only from > >him, from some source in Jersey. > > Anya, like anyone in the " business " of making > products, and in fairness to all, everyone shares a > similar interest or motivation, to earn a living at > what they love to do. > > The Oils you mention, regardless of what you may > have > sampled at the Franchise in question, are of very > good > quality. The " franchise " you visited, if it is the > one > I have in mind, did not use his oils. Many, before > even opening the franchise were discarded and > replaced > with oils obtained from local wholesale/retail > supplier, whose oils I would not purchase unless > desperate. > > > Sorry to rock your boat. I'm just truly shocked by > > some of the statements and want to figure out > what's >going on, not for me, I'm secure in my EO > experience >and usage and sources, but for the > others > > reading this. > > Just my .02 worth...... > > > > > Anya > > http://naturalperfumery.com > > The premier site on the Web to discover the beauty > > of Natural Perfume > > " The Age of the Foodie is passé. It is now the Age > > of the Scentie. " > > > > > > > > > > > > Best regards, > Carol > > _______________________________ > Never Accept Only Two Choices in Life. > The problems of Today cannot be solved by the same > thinking that created them. > -Al Einstein. > > > Mail - PC Magazine Editors' Choice 2005 > > Best regards, Carol _______________________________ Never Accept Only Two Choices in Life. The problems of Today cannot be solved by the same thinking that created them. -Al Einstein. Mail - PC Magazine Editors' Choice 2005 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 1, 2005 Report Share Posted October 1, 2005 Great articles and links, Carol. I've attached a similar sourcing for anyone whose interested in learning more about Essential Oils as medicine. - Carol Ann<saffireskyes < > Friday, September 30, 2005 9:58 PM Re: Re: Essential Oils/Medicine Ladies, and Gents, We may one day in the not too distant future put aside the semantics of whether Essential Oils are medicine or not as they may be one of the few remaining, effective defenses left in the medicinal store front. So, step it up, learn their properties and applications with regard to Influenza. INFLUENZA VIRUSES, DRUG RESISTANCE ********************************** A ProMED-mail post <http://www.promedmail.org<http://www.promedmail.org/>> ProMED-mail is a program of the International Society for Infectious Diseases <http://www.isid.org<http://www.isid.org/>> Sponsored in part by Elsevier, publisher of Tropical Infectious Diseases, 2nd Edition <http://intl.elsevierhealth.com/catalogue/title.cfm?ISBN=044306668X<http://intl.\ elsevierhealth.com/catalogue/title.cfm?ISBN=044306668X>> [1] Fri 30 Sep 2005 Cat Bachman <catbachman Source: Reuters UK, Fri 30 Sep 2005 [edited] <http://today.reuters.co.uk/news/newsArticle.aspx?type=scienceNews & storyID=2005-\ 09-30T114757Z_01_YUE042474_RTRIDST_0_SCIENCE-BIRDFLU-TAMIFLU-DC.XML<http://today\ ..reuters.co.uk/news/newsArticle.aspx?type=scienceNews & storyID=2005-09-30T114757Z\ _01_YUE042474_RTRIDST_0_SCIENCE-BIRDFLU-TAMIFLU-DC.XML>> A strain [isolate?] of the H5N1 avian influenza virus that may unleash the next global flu pandemic is showing resistance to Tamiflu, the antiviral drug that countries around the world are now stockpiling to fend off the looming threat. Experts in Hong Kong said on Friday [30 Sep 2005] that the human H5N1 strain [isolate?] which surfaced in northern Viet Nam this year had proved to be resistant to Tamiflu, a powerful antiviral drug. They urged drug manufacturers to make more effective versions of Relenza, another antiviral that is also known to be effective in battling the much-feared H5N1. Relenza is inhaled [whereas Tamiflu is taken orally]. " There are now resistant H5N1 strains [isolates] appearing, and we can't totally rely on one drug (Tamiflu), " William Chui, honorary associate professor with the Department of Pharmacology at the Queen Mary Hospital in Hong Kong, told Reuters. Chui was referring to the Tamiflu-resistant strain of H5N1 [avian influenza] in Viet Nam. Chui also said general viral resistance to Tamiflu was growing in Japan, where doctors habitually prescribe the drug to fight common influenza. Switzerland's Roche Holdings AG makes Tamiflu, known generically as oseltamivir, and GalaxoSmithKline makes Relenza, or zanamivir. " Manufacturers should think about producing an injectable form of Relenza because resistance to Tamiflu has been seen in Japan and Viet Nam. Also with injections, high doses can be given where necessary and onset time is a lot faster, " Chui said. Drugs that are administered intravenously can be better absorbed in patients who have stomach and acidity problems, another expert said. " We don't have to worry about absorption, injections take drugs right in. But if the patient takes them orally, maybe some amounts won't be absorbed or some may be destroyed by stomach acids, " said pharmacist Raymond Mak at Queen Mary Hospital. Intravenous Relenza would also ensure faster onset, which would be critical in patients who are seriously ill. " Orally taken drugs take 3-4 hours to reach maximum blood concentration and 3-4 hours is very critical in severe cases. But injectable Relenza takes only 30 minutes to reach maximum blood concentration, this is a huge difference, " Chui said. With an intravenous antiviral, doctors can also vary the doses. While the H5N1 virus is now mostly passed directly from bird to human, health experts have warned that it is just a matter of time before it mutates into a form that is easily transmissible between people. When that happens, it may result in as many as 150 million human deaths. 2 reports in The Lancet this month said that resistance to anti-influenza drugs was growing worldwide. In places such as China, drug resistance exceeded 70 percent, suggesting that drugs like amantadine and rimantadine will probably no longer be effective for treatment or as a preventive in a pandemic outbreak of flu, the reports said. [byline: Tan Ee Lyn] -- Cat Bachman <catbachman ****** [2] Fri 30 Sep 2005 ProMED-mail <promed Source: The Lancet 2005; 366:1175-1181, Fri 30 Sep 2005 [edited] <http://www.thelancet.com/journals/lancet/article/PIIS0140673605673382<http://ww\ w.thelancet.com/journals/lancet/article/PIIS0140673605673382> /abstract> Cause for Concern: Incidence of Adamantane Resistance among Influenza A (H3N2) Viruses Isolated Worldwide from 1994 to 2005 --------------- Adamantanes have been used to treat influenza A virus infections for many years. Studies have shown a low incidence of resistance to these drugs among circulating influenza viruses; however, their use is rising worldwide and drug resistance has been reported among influenza A (H5N1) viruses isolated from poultry and human beings in Asia. We sought to assess adamantane resistance among influenza A viruses isolated during the past decade from countries participating in WHO's global influenza surveillance network. We analysed data for influenza field isolates that were obtained worldwide and submitted to the WHO Collaborating Center for Influenza at the US Centers for Disease Control and Prevention between 1 Oct 1994, and 31 Mar 2005. We used pyrosequencing, confirmatory sequence analysis, and phenotypic testing to detect drug resistance among circulating influenza A H3N2 (n=6524), H1N1 (n=589), and H1N2 (n=83) viruses. More than 7000 influenza A field isolates were screened for specific amino acid substitutions in the M2 gene known to confer drug resistance. During the decade of surveillance, a significant increase in drug resistance was noted, from 0.4 percent in 1994-1995 to 12.3 percent in 2003-2004. This increase in the proportion of resistant viruses was weighted heavily by those obtained from Asia, with 61 percent of resistant viruses isolated since 2003 being from people in Asia. Our data raise concerns about the appropriate use of adamantanes and draw attention to the importance of tracking the emergence and spread of drug-resistant influenza A viruses. (Authors: Rick A Bright a, Marie-jo Medina a, Xiyan Xu a, Gilda Perez-Oronoz a, Teresa R Wallis a, Xiaohong M Davis a, Laura Povinelli b, Nancy J Cox a, and Alexander I Klimov a: the Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Influenza Branch, Atlanta, GA, USA b: Wisconsin State Laboratory of Hygiene, Madison, WI, USA). -- ProMED-mail <promed [Resistance to amantadine and rimantadine has been recorded previously, but the high frequency of resistant virus where these drugs have been used extensively over a considerable period suggests that their future usefulness will be limited. Resistance to the neuraminidase inhibitors oseltamivir and zanamivir has generally not been observed. The recent appearance of a Tamiflu-resistant avian H5N1 influenza virus in Viet Nam is an alarming development. - Mod.CP] [see also: Avian influenza, human - East Asia (120): Viet Nam 20050901.2589 Avian influenza, poultry - China: antiviral treatment 20050621.1740 2004 ---- Avian influenza - Eastern Asia (93): WHO statement 20040716.1935 Avian influenza A (H5N1) virus, human vaccine prospects 20040125.0300 Avian influenza A (H5N1) virus, drug resistance 20040125.02982001 ---- Influenza virus, neuraminidase inhibitor resistance (02) 20010928.2372 Influenza virus, neuraminidase inhibitor resistance 20010926.2350] ...............................cp/pg/dk --- Carol Ann <saffireskyes wrote: > --- rastapoodle <mccoy wrote: > > > , " Mother > > Earth's Apothecary " > > Hi Michelle: > > > 2. The other information you share - " medicinal > > grade " , no refrigeration - sound suspiciously > like > > > the incorrect information used > > by a local con artist who sells his oils to his > > students. He's the only person I've ever heard use > the term medicinal grade and no refrigeration. I > visited one of his franchise stores here and the > poor > > girl was mortified to learn she had bunk rose oil > > (orangey FO stuff) > > Hi Anya, > > I didn't realize to what extent his reputation was > so > mired within the industry...and that it is so > widespread. In some regards, it is indeed, a small > world. > > Wasn't there recently some Hulaballo about about a > gal who supposedly coined the word " hydrosol " as > being > of her origination? > > Yes, " medicinal grade " is the mantra hype of the > person in question. Medicine is the implication. > And > to some extent, I must agree in concept. Oils are > very much medicine. To be used as any other > medicine. > As are the herbs, flowers, roots they are derived > from > before distillation. Aromatherapy and Herbs have > always been considered medicine, from which many of > the Pharma's originate and are marketed. They were > used as medicine before the luxuries such as > shampoos, > scrubs, toileteries, etc they are primarily > associated > with today. Fortunately, they are once again being > taken seriously. > > That they are used for " medicinal " purposes is a > fact > that few would dispute. That they are not officially > categorized as medicine by the FDA is a boon, for > their use would surely fall prey to scrutiny, > dis/approval and limitation. We could easily find > them > on the CODEX list as well. > > That " grades " or " quality " of oils per se are > different, diluted, etc is a given. Some oils are > superior to others by virture of their procurement, > origin and processing. We can tip too toe around > semantics all day with regard to whether they are > " medicinal " > > > and terrible stock. She had invested $10k and had > to > > sue him. > > I am very familiar with that situation and the > parties > involved. As usual, there is more to the " story " > than > was disclosed to you. > > > IMO, he's a local version of Gary Young, without > the > > scandals. He advocates women squirt a pipette of > >undiluted lavender oil into their vaginas > > for infections down there! Just a horrible con > > artist, and dangerous, too. > > I cannot and will not attest to his moral character > or > integrity, one way or another. Nor would I wish to > do > so. But, for clarification, (I can see how > information > has a way or morphing into sensationalism) what IS > recommended by a local Urologist, whose medical > practice is Holistic is NOT that pipette of Lavender > be squirted into the vagina, but that few drops be > applied to a panty lining. This information was > incorporated into the teaching ciriculum and passed > on > to students as ancellary information because of the > apparent effectiveness in dealing with UT > infections. > > > > But I'm rambling. Research, and also hundreds of > > years of experience with essential oils has shown > that they need to be stored tightly-capped, in dark > bottles, away from light and heat. > > Not only from light and heat, but from disruptive > " vibrations " as well. > > > Yow. I just saw CAM. Oy, you are working with him. > > Double yow. I'll bet he insists you buy only from > >him, from some source in Jersey. > > Anya, like anyone in the " business " of making > products, and in fairness to all, everyone shares a > similar interest or motivation, to earn a living at > what they love to do. > > The Oils you mention, regardless of what you may > have > sampled at the Franchise in question, are of very > good > quality. The " franchise " you visited, if it is the > one > I have in mind, did not use his oils. Many, before > even opening the franchise were discarded and > replaced > with oils obtained from local wholesale/retail > supplier, whose oils I would not purchase unless > desperate. > > > Sorry to rock your boat. I'm just truly shocked by > > some of the statements and want to figure out > what's >going on, not for me, I'm secure in my EO > experience >and usage and sources, but for the > others > > reading this. > > Just my .02 worth...... Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.