Guest guest Posted August 14, 2005 Report Share Posted August 14, 2005 > http://www.indianpediatrics.net/mar2005/mar-255-258.htm > > Abstract: > > > > This study was conducted to determine transcutaneous absorption of oil > in preterm neonates. A mixture of coconut oil and Meadowfoam oil which > contains unique fatty acids, which acted as marker fatty acids was applied > to the skin of babies. One ml blood was collected before and one-hour > after post oil application. Both pre and post oil application serum > samples were hydrolysed and derivatised with 2-phenyl hydrazine > hydrochloride in order to detect fatty acids by HPLC analysis on C-8 > column. None of the pre oil application serum sample showed the presence > of the marker fatty acids. The post oil application serum sample of all > the 12 babies showed the presence of marker fatty acids of Meadowfoam oil > which indicates transcutaneous absorption of oil in preterm babies. > > Key words: Meadowfoam oil, Preterms, Transcutaneous absorption. > > > Zo > > > Martin, > I am kind of confused about what the body does absorb through the skin. > I > have read that the body is particularly vulnerable to lipid soluble > chemicals > with regard to exposure to toxins. Wouldn't that be true of lipid > soluble > nutrients and beneficial chemicals as well? > I am not under the impression that substances can " feed " our bodies by > entering the digestive system through the skin, but rather chemicals > entering our > system via the bloodstream and lymph system through skin absorption. > Do you (or anyone else that might chime in) have any wisdom to share > regarding what the skin does absorb? > > Thanks, > Mary Alana > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 16, 2005 Report Share Posted August 16, 2005 > http://www.indianpediatrics.net/mar2005/mar-255-258.htm This Indian study comes up with opposite conclusions to previous work on pre term babies. Similar studies were published in: Archives of Diseases in Childhood 1993; 68:27-28. In that study they used Safflower oil in the hope they could use this as a way to boost these infants levels of essential fatty acids. It did not work and their conclusion was " We found no evidence to suggest that the transdermal route is of use in nutritional management of pre term infants " . The other misleading issue is that these infants have the most delicate skin possible. There is no way you can equate such results to those on an adult whose skin is far thicker, denser and less porous. I note this summary does not give the volumes of the fatty acids detected, simply that they were. Another problem is that the injection needle taking blood samples, can be contaminated as it passes into the skin. Modern analytical techniques are so incredibly sensitive that the tiniest volumes that are detected in the sample may have simply come from contamination of the needle. In absorption tests that I advised on, the samples were taken through bags that had previously been taped to the skin with a syringe inside it. If such precautions are not taken, then analytical results are highly suspect. I never rely on internet summaries and will get a copy of the whole paper next time I am in London. I will say more when I get chance to study this whole report. Martin Watt , " Zonella Gould " <zonella@t...> > > > > This study was conducted to determine transcutaneous absorption of oil > > in preterm neonates. A mixture of coconut oil and Meadowfoam oil which > > contains unique fatty acids, which acted as marker fatty acids was applied > > to the skin of babies. One ml blood was collected before and one- hour > > after post oil application. Both pre and post oil application serum > > samples were hydrolysed and derivatised with 2-phenyl hydrazine > > hydrochloride in order to detect fatty acids by HPLC analysis on C-8 > > column. None of the pre oil application serum sample showed the presence > > of the marker fatty acids. The post oil application serum sample of all > > the 12 babies showed the presence of marker fatty acids of Meadowfoam oil > > which indicates transcutaneous absorption of oil in preterm babies. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 16, 2005 Report Share Posted August 16, 2005 Martin this study was done in 1993, 12 years ago. Do you have any research more recent? Julia Graber Cregger Graber Girl By Julia Quote Link to comment Share on other sites More sharing options...
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