US-EPA data on Fluoride toxicity

[Guest guest]

Hi All,

 

The US-EPA accepts a higher F intake than the Japanese report.

http://tinyurl.com/cszkhc says: It has been estimated that the development of

crippling skeletal fluorosis in man requires the consumption of 20mg or more of

fluoride/person/day over a 20-year period, i.e., 0.28 mg/kg/day (U.S. EPA,

1985). While the NOEL for crippling skeletal fluorosis in humans is unknown, a

safe level of fluoride exposure can be determined. No cases of crippling

skeletal fluorosis have been observed in the United States associated with the

consumption of 2 L of water/day containing 4 ppm fluoride (50 FR 20614).

Assuming a 70 kg adult ingests 0.01 mg fluoride/day in the diet and consumes 8

mg fluoride/ day in drinking water (2 L/day containing 4 ppm fluoride), this

would correspond to a total intake of 0.12 mg/kg/day. Thus, 0.12 mg

fluoride/kg/day is a safe exposure level for this more severe endpoint in

adults.

 

Summary: US-EPA accepts 0.12mg F / kg bodyweight / day as SAFE, whereas the

Japanese report regards 0.1mg F / kg /day as potentially dangerous.

 

Best regards,