natural Potassium Sorbate

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http://www.omri.org/Ksorbate_final.pdf The toxicity and mode of action of the substance and of its breakdown products or any contaminants, and their persistence and areas ofconcentration in the environment. Potassium sorbate has an oral LD 50 of 3,800 mg/kg for mice and 4,340 mg/kg for rats (Binas, 2001). The ‘safe’ levelof potassium sorbate in the diet of a model insect, Agria affinis was determined to be 200 ppm (Singh and House,1970). It is a skin and eye irritant and decomposes into an irritant. There is no indication that potassium sorbate or itsbreakdown products are carcinogenic, teratogenic, or mutagenic. Replications of earlier trials to evaluate thegenotoxicity of potassium sorbate confirmed the earlier negative findings using Drosophilia (fruit flies) (Schlatter etal., 1992) and hamsters (Münzer, 1990) as models. However, there is evidence of cytotoxicity. One study showed thatrats exposed to potassium sorbate had detectable cell injury. The injury levels were reduced by the introduction of anantioxidant (Sugihara, Shimomichi, and Furuno, 1997 3. The probability of environmental contamination during manufacture, use, misuse, or disposal of the substance. Crotonaldehyde and ketene are both produced from fossil fuel sources, primarily natural gas and petroleum. Petroleum production is associated with the destruction of wildlife habitat and creates greenhouse gases that are believed to be the cause of global warming. 4. The effects of the substance on human health. Potassium sorbate is Generally Recognized As Safe (GRAS) as a food additive in the US (21 CFR 182.3640). It is an irritant of skin and eyes. Inhalation and ingestion can also cause acute health hazards (Binas, 2001)