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Calcification and Its Treatment with Magnesium and Sodium Thiosulfate

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ment-with-magnesium-and-sodium-thiosulfate/_

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thiosulfate/)

 

Mark Sircus Ac., OMD International Medical Veritas Association

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(director)

 

 

 

[PICTURE]

Cardiac CT showing calcified plaques.

 

 

Calcium plays a central role in the electrical stimulation of cardiac

cells and in the mechanical contraction of smooth muscle cells in the wails of

arteries.

 

 

Calcium is essential to health yet it holds a hidden danger that brings us

to our graves much quicker then we would like. Calcium is the most

promoted nutrient by proponents of conventional, nutritional, and alternative

medicine. This is a great and tragic mistake. They should have been promoting

magnesium. Magnesium deficiency leads to an increase in myocardial levels of

both sodium and calcium. This is a problem because Coronary Artery calcium

is a predictor of near-term coronary heart disease events. In the face of

growing magnesium deficiencies calcium becomes increasingly more toxic to

human physiology.

 

 

Dr. Dean makes this clear when she says in her book The Magnesium Miracle,

" To understand how you can create a calcium/magnesium imbalance in your

own body, try this experiment in your kitchen. Crush a calcium pill and see

how much dissolves in 1 oz of water. Then crush a magnesium pill and slowly

stir it into the calcium water. When you introduce the magnesium, the

remaining calcium dissolves; it becomes more water-soluble. The same thing

happens in your bloodstream, heart, brain, kidneys, and all the tissues in your

body. If you don't have enough magnesium to help keep calcium dissolved, you

may end up with calcium-excess muscle spasms, fibromyalgia, hardening of

the arteries, and even dental cavities. Another scenario plays out in the

kidneys. If there is too much calcium in the kidneys and not enough magnesium

to dissolve it, you can get kidney stones. "

 

 

Magnesium and calcium work together to control muscle action though

calcium becomes a problem when there is not enough magnesium to control

calcium's

actions. Calcium becomes a slow acting poison (often decades of build up)

to tissues all over the body when in excess relative to magnesium in

deficiency. Trace mineral symptoms of excess or deficiency depend on their

ratios

to other elements. In the event of calcification, it is not particularly a

high calcium level that results in the formation of a stone or spur, but

calcium being high in ratio to magnesium.

 

 

Magnesium increases the solubility of calcium in the urine.

Supplementing magnesium to the diet has demonstrated significant effect in

preventing recurrences of kidney stones.

 

 

If calcium is not taken with magnesium or it if it is not highly

absorbable, it will cause much more harm than good. Unabsorbed calcium can

lodge

anywhere in our body. For instances, if it lodges in your bones and joints,

it mimics arthritis; if it lodges in you heart, it mimics arterial lesions.

Calcification or calcium poisoning can manifest as heart disease, cancer,

wrinkled skin, kidney stones, osteoporosis, dental problems, bone spurs,

cataracts and many other health problems. Calcium deposits in the joints are

called arthritis; in the blood vessels it is hardening of the arteries; in

the heart it is heart disease, and in the brain it is senility.

 

 

It is magnesium that actually controls bone density not calcium.

Magnesium drives the calcium into the bones where low levels encourage its

loss.

 

 

Exceedingly few healthcare practitioners in the world have learned much

about magnesium medicine so they do not know to lay off the calcium and start

intensive magnesium treatments. After decades of dairy industry marketing

pushing calcium we have a situation that is literally killing millions of

people. Anyone who wants to live longer should pay attention to the magnesium

story and should immediately begin a strong and prolonged treatment with

magnesium in its chloride form. Magnesium chloride is the most versatile,

absorbable and effective form of magnesium and can be used orally,

transdermally and via IV drip. It can even be nebulized directly into the lungs

and

in much diluted form dropped into the eyes when its purest forms are used.

 

 

While calcium affects muscle contractions, magnesium balances that effect

and relaxes muscles. Calcium tightens the muscles; magnesium relaxes the

muscles. With insufficient magnesium the muscles stay tense and through the

years may cause a cramp in the muscle. This could happen when you have too

much calcium or too little magnesium. Too much calcium causes the heart to

go into a spasm and it can't relax. This is a heart attack. Get some

magnesium into the body and the heart will slowly start returning to normal

unless

major damage has already been done. Add iodine and selenium and we have

the makings of an ideal formula to support recovery and possibly even minor

tissue regeneration.

 

 

As we will see in another chapter medical scientists are already creating

heart patches made from sea weed and are seeing both blood and heart

tissues growing and regenerating into the patches. Seaweed just happens to be

high in magnesium, iodine and selenium. A great part of this book will be

devoted to mercury poisoning and the tendency of it to be concentrated in

cardiac tissues. Selenium is the antidote to mercury and iodine reveals one more

of her secrets when it comes to cardiac care.

 

 

[GRAPH]

 

Characterization of liver calcification.

Von Kossa (top panels), alizarin red S (middle panels) and Goldner-Masson

trichrome (bottom panels) staining of calcified, precalcified and

noncalcified liver tissue sections. Top panels, black staining indicates the

presence of phosphate precipitate.

Middle panels, dark grey staining indicates the presence of Ca2+

precipitate.

Bottom panels, light grey staining indicates the presence of collagen.

Magnification 20.

 

 

There are no pharmaceutical drugs on the market to reduce calcium deposits

but magnesium chloride and sodium thiosulfate are useful in preventing and

treating unwanted calcification. Together they offer the best way of

combating the calcium time bomb going silently and slowly off in uncounted

millions of people. The best way to track calcium toxicity is actually through

looking at the level of deficiency in magnesium for magnesium controls and

counteracts calcium. The average American consumes only 40 percent of the

recommended daily allowance of magnesium. This has serious consequences,

including death, in many people, according to magnesium expert Dr. Mildred

Seelig. Eighty to 90 percent of the U.S. population is magnesium deficient.

 

 

Calcification consists of calcium and phosphorous and is a normal process

for building healthy bones and teeth. But it also plays a central role in

disease conditions such as strokes and heart attacks.

 

 

Dr. H. Ray Evers writes, " The power plant of human cell is called the

" mitochondrion. " The mitochondrion is what generates energy for the cell to

use. What everyone refers to as " energy " is derived from the oxidative

reduction of the cellular respiration. This is done through the mitochondria.

But

the problem arises when the cell is low in magnesium, relative to calcium.

Adenosine triphosphate, the " energy currency " of the cell, is magnesium

dependent. This means it is obvious that the calcium pump at the cell membrane

is also magnesium dependent. Without enough " biologically available "

magnesium, the cellular calcium pump slows down. Thus a vicious cycle is

established. The low levels of available magnesium inhibit the generation of

energy, and the low levels of energy inhibit the calcium pump. The end result?

The mitochondrion, the powerhouse of the cell and the entire body, becomes

calcified. This is the beginning of aging. It all starts in the cell. First

the cells age. This leads to organ aging. And after the organs age,

individual aging occurs. Since calcium is readily accumulated by mitochondria,

this ion is potentially capable of antagonizing the activating influence of

magnesium on many intra-mitochondrial enzyme reactions. This means that every

function of your body can be inhibited when the mitochondria calcify. It's

like going through life with the emergency brakes on. Calcium is the

brake. Magnesium is the accelerator. To be in optimal health, there must be a

balance between the two. "

 

 

The higher the protein you consume the more magnesium is needed.

When large amounts of calcium are consumed, you need more magnesium.

A diet which is high in calcium increases the body's need for magnesium.

Dr. H. Ray Evers

 

 

The higher the calcium level and the lower the magnesium level in the

extra-cellular fluid, the harder it is for cells to pump the calcium out.

Mitochondria produce the energy our cells and organs need. This is vitally

important for the heart because heart muscle cells have a never ending need for

energy. Mitochondria are also important for proper neurotransmission and

are highly concentrated in cells of the brain and central nervous system. A

healthy cell has high magnesium and low calcium levels.

 

 

[PICTURE]

Calcifying Nanoparticles (CNPs) form slow-growing calcified colonies in

arteries and organs, much in the same way as coral reefs form.

 

 

We may say that our biochemical age is determined by the ratio of

magnesium to calcium within our cells. As we age, calcium deposits tend to

accumulate in our soft tissues. Doctors call it " Extra-skeletal calcification. "

This means that the calcium that is supposed to be deposited in your bones is

being lodged in our soft tissues.

 

 

Up to 30% of the energy of cells is used to pump calcium out of the cells.

 

 

Deficiency in magnesium, aside from having a negative impact on the energy

production pathway required by mitochondria to generate ATP, also reduces

the threshold antioxidant capacity of the cardiovascular system and its

resistance to free-radical damage. Magnesium acts as an antioxidant against

free radical damage of the mitochondria.

 

 

Magnesium has been called nature's " calcium channel blocker " because of

its ability to prevent coronary artery spasm, arrhythmias, and to reduce

blood pressure.

 

 

" Calcium enters the cells of the heart by way of calcium channels that are

jealously guarded by magnesium. Magnesium, at a concentration 10,000 times

greater than that of calcium in the cells, allows only a certain amount of

calcium to enter to create necessary electrical transmissions, and then

immediately helps to eject the calcium once the work is done. Why? If calcium

accumulates in the cell, it causes hyperexcitibility and calcification and

disrupts cell function leading to angina, high blood pressure, arrhythmia,

asthma, headaches and even heart attacks. Magnesium is nature's calcium

channel blocker, " says Dr. Carolyn Dean, author of The Magnesium Miracle.

 

 

Dr. Garry Gordon wrote, " If you have compromised cell membranes or low ATP

production for any reason, then the cell has trouble maintaining the

normal gradient. This is because the usual gradient is 10,000 times more

calcium

outside of cells than inside; when this is compromised you will have

increased intracellular calcium, which seems to always happen at the time of

death. Whenever intracellular calcium is elevated, you have a relative

deficiency of magnesium, so whenever anyone is seriously ill, acute or chronic,

part of your plan must be to restore magnesium, which is poorly absorbed

through oral means. "

 

 

[PICTURE]

The optimal blood serum value for vitamin D is 45-52 ng/ml (115-128

nmol/l).

 

 

The adverse effects of excessive calcium intake may include high blood

calcium levels, kidney stone formation and kidney complications.[1] Elevated

calcium levels are also associated with arthritic/joint and vascular

degeneration, calcification of soft tissue, hypertension and stroke, and

increase

in VLDL triglycerides, gastrointestinal disturbances, mood and depressive

disorders, chronic fatigue, and general mineral imbalances including

magnesium, zinc, iron and phosphorus. High calcium levels interfere with

Vitamin

D and subsequently inhibit the vitamin's cancer protective effect unless

extra amounts of Vitamin D are supplemented.[2]

 

 

Vitamin D works by lowering insulin resistance, which is one of the major

factors in heart disease. It is also used by the thyroid gland, which

secretes a hormone that regulates the body's levels of calcium, which in turns

helps regulate blood pressure.

 

 

Cardiovascular calcification lesions can lead to the development of

myocardial ischaemia, myocardial infarction, impaired myocardial function,

congestive heart failure, cardiac valve insufficiency, and cardiac arrhythmias.

There is a strong association between increased cardiac calcification and

risk of death. Administration of vitamin D to treat secondary

hyper-parathyroidism increases intestinal absorption of calcium and phosphorus.

It raises

serum calcium and phosphorus levels. Soft-tissue and vascular calcification

are associated with a history of vitamin D therapy.[3]

 

 

Changes in serum calcium do provide important information about various

hormonal or organic disturbances, including excessive Vitamin D status.

 

 

Magnesium and calcium share a common route of absorption in the intestinal

tract and appear to have a mutually suppressive effect on each other. If

calcium intake (or dairy intake) is unusually high, calcium will be absorbed

in preference to magnesium. Also, excessive doses of vitamin D and calcium

supplements can cause renal magnesium loss. Sunlight is the only safe way

to get vitamin D since the body regulates how much is made. Take it by

pill form and calcium homeostasis is overridden. The entire idea of toxic

sunscreens and avoiding the sun's life giving effects (natural vitamin D

formation) is just one more mistake modern medicine is making.

 

 

Researchers from Winthrop University Hospital in Mineola, New York, found

that giving supplements of vitamin D to a group of volunteers reduced

episodes of infection with colds and flu by 70 per cent over three years.

 

 

The dangers of sun exposure have been greatly exaggerated by the same

types of people who over exaggerate and lie about many things in medicine. Sun

exposure is not the major reason people develop skin cancer. Researchers

point out that increasing level of vitamin D3 could prevent many diseases

that claim hundreds of thousands if not millions of people world each year.

Vitamin D, the sunshine vitamin, is different from other vitamins in that it

influences your entire body - receptors that respond to the vitamin have

been found in almost every type of human cell, from the brain to our bones.

 

 

Magnesium is essential for the normal function of the parathyroid gland

and for vitamin D metabolism.

[PICTURE]

 

 

 

Coronary artery calcification is common, is severe and is significantly

associated with ischemic cardiovascular disease in adult end-stage renal

disease patients.[4] The amount of calcium in the coronary arteries reliably

predicts heart attack risk and is measured by what is called ones calcium

score. UCLA cardiologist, Dr. Matt Budoff, a long-time champion of the

Coronary Calcium Scan, and author of the AHA paper says, " The total amount of

coronary calcium (Agatston score) predicts coronary disease events beyond

standard risk factors. " The Coronary Calcium Score is a precise quantitative

tool for measuring and tracking heart disease risk. It is more valuable and

accurate than other traditional markers (such as total cholesterol which is

practically worthless as a heart disease risk marker).

 

 

[PICTURE]

This image demonstrates coronary artery calcification.

 

 

According to the University of Florida Shands Cancer Center a high level

of calcium in the blood, called hypercalcemia,[5] may become a medical

emergency. This disorder is most commonly caused by cancer or parathyroid

disease but underneath the primary etiology is a magnesium deficiency.

Hypercalcemia is commonly attributed to cancer treatment. Severe hypercalcemia

is a

medical emergency that can be avoided if magnesium levels are brought up to

normal.

 

 

Magnesium is the mineral of rejuvenation and prevents the calcification of

our organs and tissues that is characteristic of the old-age related

degeneration of our body.

 

 

Magnesium inadequacy interferes with cellular metabolism and accelerates

the aging of most human tissues. Most human cells can only replicate a

limited number of times in cultures before they lose the ability to divide, a

phenomenon known as replicative senescence. Recent studies have shown that

culture in low magnesium accelerates the senescence of human endothelial

cells and fibroblasts.[6] Dr. James Howenstein says " Calcification in cellular

tissues is a sign of tissue damage, cellular aging and impending cell

death. When cells are unable to regulate calcium and keep the calcium content

of

cells down cellular function degenerates. Calcified arteries, calcium in

soft tissues and high levels of calcium within cells are all signs of aging.

At age 80 the average calcium content in the aorta is 140 times greater

than the levels of aortic calcification noted at age 40. "

 

 

[PICTURE]

Age 20-30 years Age 50-70 years

 

 

In youth, at left, there is minimal plaque formation. However, at right

with passage of time the plaque grows larger. About 20% of this plaque

volume contains calcium which is measurable on CAT scan, providing a marker for

the total plaque burden. Calcification of atherosclerotic lesions is due to

a process of active deposition of calcium in the atherosclerotic plaque

that utilizes metabolic pathways similar to those found in normal human bone.

Calcium accumulates steadily in plaque and its presence is verifiable via

microscopic examination from the very early stages of disease formation.

Having a build-up of calcium plaque in the arteries means increased risk of

heart attacks and death from heart disease according to findings from the

Multi-Ethnic Study of Atherosclerosis (MESA) funded by the National Heart,

Lung, and Blood Institute. Researchers at the University of Virginia Health

System suggest that composition of plaque deposits in the carotid arteries

indicate a patient's risk of having a stroke.

 

 

The ratio of calcium to magnesium in milk is 9 or 10 to 1.

Calcium is the physiological partner of magnesium and should be present in

a 2:1 or even 1:1 ratio.

 

 

American women have been consuming an average of two pounds of milk per

day for their entire lives, yet thirty million American women have

osteoporosis. Drinking milk does not prevent bone loss. Bone loss is

accelerated by

ingesting too much protein, and milk has been called " liquid meat. " In order

to absorb calcium, the body needs comparable amounts of magnesium.

Countries with the highest rates of osteoporosis, such as the United States,

England, and Sweden, consume the most milk. China and Japan, where people eat

much less protein and dairy food, have low rates of osteoporosis.[7] Dietary

protein increases production of acid in the blood which can be neutralized

by calcium mobilized from the skeleton.[8] About 50,000 Americans die each

year of problems related in some way to osteoporosis.[9]

 

 

[PICTURE]

 

Aortic valve replacements are done when too much calcification of the

heart valve leaflets takes place. According to The Cleveland Clinic,

fibro-calcific degeneration most commonly affects the aortic valve. According

to

reports, calcified heart valves typically occurs in adults over the age of 65.

When valve leaflets are calcified, the valve leaflets become fibrotic

(thickened) and calcified (hardened), producing a narrowed valve opening. Risk

factors for this type of valve disease include increased age, low body

weight and high blood pressure.

 

 

[PICTURE]

This photograph shows the aortic valve with a short segment of the aorta

around it. The valve clearly has only two cusps (bicuspid aortic valve), and

is narrowed and densely calcified. If you placed your fingertip through

the opening, the valve would feel hard and gritty.

 

 

William R. Quesnell, author of 'Minerals: The Essential Link to Health,

said, " Most people have come to believe nutrition is divisible, and that a

single substance will maintain vibrant health. The touting of calcium for the

degenerative disease osteoporosis provides an excellent example. Every day

the media, acting as proxy for the milk lobby, sells calcium as a magic

bullet. Has it worked? Definitely for sales of milk; but for American health

it has been a disaster. When you load up your system with excess calcium,

you shut down magnesium's ability to activate thyrocalcitonin, a hormone

that under normal circumstances would send calcium to your bones. "

 

 

The most common cause of death in dialysis patients is cardiovascular

disease. This is due in part to the presence of excess vascular calcification,

particularly in the form of extensive coronary artery calcification, which

can be observed even in very young dialysis patients.[10] The presence of

coronary artery calcification in the dialysis population appears to

correlate in part with the ingested quantity of calcium-containing oral

phosphate

binders.[11]

 

 

The associations among valvular calcification, inflammation, carotid

atherosclerosis, and arterial calcification suggest that valvular calcification

is a marker of atherosclerosis and arterial calcification in patients with

end stage renal disease.[12]

 

 

Dietary surveys clearly show that magnesium, not calcium, intakes have

been falling over the last fifty years. This is a problem because it is

magnesium that controls the fate of calcium in the body. If magnesium is

insufficient calcium will be deposited in the soft tissues (kidneys, arteries,

joints, brain, etc.).

 

 

Countries with the highest calcium to magnesium ratios (high calcium and

low magnesium levels) in soil and water have the highest incidence of

cardiovascular disease. At the top of the list is Australia. Adequate levels of

magnesium are essential for the heart muscle. Some researchers predict that

the American ratio of calcium to magnesium is actually approaching 6-to-1,

yet, the recommended dietary ratio of calcium to magnesium in the United

States is 2-to-1. The process of absorption for magnesium is similar to that

of calcium but some people absorb or retain much more magnesium than

calcium (or more calcium than magnesium). The commonly suggested supplemental

intake ratio of 2:1 for calcium and magnesium is arbitrary for the value can

change significantly under various individual circumstances.

 

 

Current research on the Paleolithic or caveman diet shows that the ratio

of calcium to magnesium in the diet that our bodies evolved to eat is

1-to-1.[13] Balancing this information is the fact that mothers breast milk is

ten parts calcium to only one part magnesium so it seems that at least early

in life we need less magnesium and more calcium to build strong bones

Though high doses of calcium carbonate taken alone over a long period of time

will lead to low magnesium levels,[14] magnesium is what is needed to

encourage the correct utilization of calcium by the body to increase bone

strength.[15] Researchers estimate currently that the ratio should be two parts

calcium to one part magnesium.[16]

 

 

Without magnesium, calcium is not fully utilized, and under absorption

problems may occur leading to arthritis, osteoporosis, menstrual cramps, and

some premenstrual symptoms.

 

 

In contrast to skeletal muscle, cardiac muscle cannot contract in the

absence of extracellular calcium ions as well as extracellular potassium ions.

In this sense, it is intermediate between smooth muscle, which has a poorly

developed sarcoplasmic reticulum and derives its calcium across the

sarcolemma; and skeletal muscle which is activated by calcium stored in the

sarcoplasmic reticulum (SR). The reason for the calcium dependence is due to

the

mechanism of calcium-induced calcium release (CICR) from the SR that must

occur under normal excitation-contraction (EC) coupling to cause

contraction.

 

 

According to Dr. Sarah Mayhill, " Calcium and magnesium compete for

absorption and so too much calcium in the diet will block magnesium absorption.

Our physiological requirement for calcium to magnesium is about 2:1. In dairy

products the ratio is 10:1. So, consuming a lot of dairy products will

induce a magnesium deficiency. "

 

 

A diet high in dairy and low in whole grains can lead to excess calcium in

the tissues and a magnesium deficiency.[17]

Dr. Nan Kathryn Fuchs

 

 

pH

 

 

The general theory behind increased calcium intake is that calcium will

combat excess acidity, thus helping to promote good health. This is only half

true: While the body uses calcium as a buffer, excess calcium can also

promote soft-tissue calcification. Too much calcium running amuck through your

body is the real danger of excess acidity. It is far better to increase

your intake of other buffers such as magnesium, which will safely buffer

excess acidity without causing calcifications. Of course, eating a so-called

alkaline diet and limiting your intake of acidic minerals such as phosphorus

may also help. Acidic minerals can contribute to calcifications. In

essence, the real danger of excess acidity is the leeching of calcium that it

causes. Simply put, excess acidity equals soft-tissue calcifications.

 

 

The chemical reaction of magnesium is alkaline (acid binding).

It regulates the acid-alkaline balance of the body.

Dr. H. Ray Evers

 

 

According to Dr P Kaye, Emergency Department, Bristol Royal Infirmary, UK,

" Magnesium acts as a smooth muscle relaxant by altering extracellular

calcium influx and intracellular phosphorylation reactions. It may also

attenuate the neutrophilic burst associated with inflammatory

bronchoconstriction

by attenuating mast cell degranulation. The principal trigger for this

degranulation is a rise in intracellular calcium, which is antagonised by

magnesium. It has been shown experimentally to augment the bronchodilatory

effect of salbutamol and to inhibit histamine induced bronchospasm. Magnesium

should be used as a safe, easy to administer and effective second line agent

in acute severe asthma.[18]

 

 

Medical authorities claim that the widespread incidence of osteoporosis

and tooth decay in western countries can be prevented with a high calcium

intake. However the opposite is true. Asian and African populations with a

very low intake of about 300 mg of calcium daily have very little

osteoporosis. Bantu women with an intake of 200 to 300 mg of calcium daily have

the

lowest incidence of osteoporosis in the world. In western countries with a

high intake of dairy products the average calcium intake is about 1000 mg.

With a low magnesium intake, calcium goes out of the bones to increase tissue

levels, while a high magnesium intake causes calcium to go out of the

tissues into the bones. Thus high magnesium levels leads to bone

mineralization.

 

 

Some gynecologists believe that one of the first organs to calcify is the

ovaries, leading to pre-menstrual tension.

 

 

Dr. Karen Kubena, associate professor of nutrition at Texas A & M

University indicates that even if you monitor your magnesium level like a

maniac,

you're still at risk for migraines if your calcium level is out of whack. It

seems that higher than normal blood levels of calcium cause the body to

excrete the excess calcium, which in turn triggers a loss of magnesium.

" Let's say you have just enough magnesium and too much calcium in your blood. If

calcium is excreted, the magnesium goes with it. All of a sudden, you could

be low in magnesium, " says Dr. Kubena.

 

 

As a general rule, acid substances tighten; and alkaline substances relax.

Magnesium is alkaline and relaxes the body from tightness, tension,

stiffness, spasms, twitches, tics or jerkiness as in nervousness, anxiety,

anger, fear, agitation, headaches, muscle cramps, menstrual cramps, arthritis,

insomnia, constipation, heart palpitations, irregular heartbeats, high blood

pressure, eye twitches, acne, plaque on teeth, plaque on heart and

arteries due to cholesterol build-up, plaque on the brain [Alzheimer's].

Magnesium

acts as a natural gate or valve in the brain synapses that regulates

influx of calcium into postsynaptic calcium channels from presynaptic neurons

in

parts of the brain that are involved in mood and behavior such as the

hippocampus. With inadequate magnesium (calcium toxicity), this function

becomes altered and irritability, anxiety, depression, ADHD, mania, hypo-mania,

bi-polar disorder, hyper-excitability and hyper-emotionality, and perhaps

some psychoses, result.

 

 

A pH less than 5.3 indicates an inability to assimilate vitamins or

minerals. Due to the alkalinity of minerals, they loosen tumors, including

fibroid tumors, endometriosis, cysts, moles, warts, skin tags, and other

growths,

and cause them to release their toxins. Magnesium should be used to buffer

acid pH, not the calcium that is being leached from the bones.

 

 

Magnesium taken in proper dosages can solve the problem of calcium

deficiency.

Dr. Nan Kathryn Fuchs

 

 

Experts say excessive calcium intake may be unwise in light of recent

studies showing that high amounts of the mineral may increase risk of prostate

cancer. " There is reasonable evidence to suggest that calcium may play an

important role in the development of prostate cancer, " says Dr. Carmen

Rodriguez, senior epidemiologist in the epidemiology and surveillance research

department of the American Cancer Society (ACS). Rodriguez says that a 1998

Harvard School of Public Health study of 47,781 men found those consuming

between 1,500 and 1,999 mg of calcium per day had about double the risk of

being diagnosed with metastatic (cancer that has spread to other parts of

the body) prostate cancer as those getting 500 mg per day or less. And those

taking in 2,000 mg or more had over four times the risk of developing

metastatic prostate cancer as those taking in less than 500 mg.

 

 

The recommended daily allowance (RDA) of calcium is

1,000 mg per day for men and 1,500 mg for women.

 

 

Later in 1998, Harvard researchers published a study of dairy product

intake among 526 men diagnosed with prostate cancer and 536 similar men not

diagnosed with the disease. That study found a 50% increase in prostate cancer

risk and a near doubling of risk of metastatic prostate cancer among men

consuming high amounts of dairy products, likely due, say the researchers,

to the high total amount of calcium in such a diet. The most recent Harvard

study on the topic, published in October 2001, looked at dairy product

intake among 20,885 men and found men consuming the most dairy products had

about 32% higher risk of developing prostate cancer than those consuming the

least. Dr. Panagiota N. Mitrou, of the National Cancer Institute,

Rockville, Maryland, and colleagues found the same thing, that increased

consumption

of calcium and dairy products raises the risk of prostate cancer.

 

 

Treatment with Sodium Thiosulfate

 

 

Sodium thiosulfate (STS) is a calcium chelating agent with antioxidant

properties.

Dr. Carlos E. Araya

 

 

[PICTURE]

Figure 1. (A) Initial three-phase bone scan demonstrating soft tissue

accumulation in thighs, distal femur, proximal tibia, and forearms. There is

intense uptake in the myocardium and early accumulation in the lungs. (B)

Three months later, the calcium deposition in the thighs and forearms is less

significant. However, there still is calcification in the heart, lungs, and

para-articular surfaces.

 

 

Sodium thiosulphate results in the formation of calcium thiosulphate in

the urine, a compound with much higher solubility than the other calcium

salts (phosphate, oxalate). Thus, sodium thiosulphate could not only inhibit

further nephrocalcinosis, but in some degree it could contribute to

decalcification of renal parenchyma[19].

 

 

The beneficial effects of sodium thiosulfate (STS) are thought to be due

in part to its ability to enhance the solubility of calcium deposits. STS

has a small molecular weight of 248 (Na2S2O3) and in patients with normal

renal function has a serum half-life of 15 min. STS facilitates the

mobilization of calcium from vessels affected by calcium deposits.

 

 

Intravenous STS seems beneficial, has mild adverse effects, and is well

tolerated in children and young adults. STS dosage was 25 g/1.73 m2 per dose

intravenously.

Dr. Carlos E. Araya

 

 

Dr. Carlos E. Araya et al[20] successfully used this relatively nontoxic

substance, which been reported as adjuvant treatment of several conditions

involving disorders of calcium homeostasis. Yatzidis described its benefits

by decreasing the rate of new kidney stone development in 34 patients with

recurrent calcium urolithiasis. Prompted by these excellent results,

intravenous STS was administered after hemodialysis to three patients with ESRD

and tumoral calcinosis for a period of 6 to 12 mo. Two of the patients had

regression of the calcified mass as well as improved motility of the

affected joints. STS was given for a period of 9 yr to a patient with

nephrocalcinosis as a result of renal tubular acidosis type 1. There was no

further

deterioration of his condition, and the discontinuation of the medication was

accompanied by recurrence of renal colic. See later chapter for the full

story on sodium thiosulfate.

 

 

Body pH and Calcium

 

 

Many health care professionals believe there is only one disease. And that

one disease is acidosis. The wastes produced from food are highly acidic

and acidosis is one of the main contributors that lead to the aging process

and various illnesses. Acid waste is excreted from the human body in the

form of urine or sweat. But the wastes not excreted will be circulating

around in the blood, in the body. This acidic waste will gradually accumulate

somewhere in our capillaries blood vessels, and eventually clog them up. Also

as a consequence of this, the cells of the human body will be deprived of

their supply of oxygen and essential nutrients, rendering these cells

inactive in reproduction. That's the main reason why people age. Moreover, with

the capillary blood vessels clogged up, the function of every organ in the

human body accumulating acidic waste will begin to deteriorate, causing

serious illnesses in the long run.

 

 

One of the first warning signs of an acidic biological terrain is calcium

deposits. Our dietary intake of calcium is not keeping up with the calcium

buffering needed and we are actively pulling calcium from our bones and

teeth. It all works like a little train, from the bones to the fluids and

cells, to the blood. As our biological terrain becomes acidic, our pH level

drops. When this happens we start losing calcium out of the blood, the bones,

and the tissues. This is a safety mechanism. Now your biological terrain's

oxygen level drops leaving you tired and fatigued, allowing fungus, mold,

parasites, bad bacteria, and viral infections to flourish and gain a hold

throughout the body. It is interesting to note that you often won't have just

some of these invaders. If you have Candida you will likely have bad

bacteria, fungus, and parasites because they all flourish in the same terrain.

 

 

Mild acidosis can cause such problems as: ·

 

-- Cardiovascular damage, including the constriction of blood vessels and

the reduction of oxygen.

 

-- Weight gain, obesity and diabetes.

 

-- Bladder and kidney conditions, including kidney stones.

 

-- Immune deficiency.

 

-- Acceleration of free radical damage, possibly contributing to cancerous

mutations.

 

-- Premature aging.

 

-- Osteoporosis; weak, brittle bones, hip fractures and bone spurs.

 

-- Joint pain, aching muscles and lactic acid buildup.

 

-- Low energy and chronic fatigue.

 

 

A recent seven year study conducted at the University of California, San

Francisco, on 9,000 women showed that those who have chronic acidosis are at

greater risk for bone loss than those who have normal pH levels. The

scientists who carried out this experiment believe that many of the hip

fractures prevalent among middle aged women are connected to high acidity caused

by

a diet rich in animal foods and low in vegetables. This is because the

body borrows calcium from the bones in order to balance pH.

 

 

American Journal of Clinical Nutrition

The biggest problem scientists have found is that over time the human body

becomes depleted of calcium. A compound called mono-ortho-calcium

phosphate is the chemical buffer for the blood. This buffer maintains the

alkaline

level (or the lack of acidity) in your blood. Without it you would die. If

the acidity level of your blood changes even slightly, you die immediately!

But in order to supply enough calcium for buffering we must have enough

calcium being absorbed from our diet. If not, our body will simply rob the

needed calcium from our bones and teeth. The more acidic we become, the

harder it is for oxygen to be present, so our biological terrain also becomes

more anaerobic. Without adequate oxygenation, unfriendly bacteria, viruses,

molds, and fungus can live and prosper. Then our cells cannot carry on their

life-giving functions in a very efficient manner because our biological

chemical reactions need oxygen.

 

---------------------

 

[1] New York State Department of Health;

_http://www.health.state.ny.us/diseases/conditions/osteoporosis/qanda.htm_

(http://www.health.state.ny.us/diseases/conditions/osteoporosis/qanda.htm)

 

[2] Accu-Cell Nutrition; Calcium and Magnesium

_http://www.acu-cell.com/acn.html_ (http://www.acu-cell.com/acn.html)

 

[3] Nephrol Dial Transplant (2002) 17: 336-339 Cardiovascular

calcification in end-stage renal disease. Isidro B. Salusky1, and William G.

Goodman2 1

Department of Pediatrics and 2 Department of Medicine, UCLA School of

Medicine, Los Angeles, CA, USA

 

[4] J Am Coll Cardiol, 2002; 39:695-701. J Am Coll Cardiol, 2002;

39:695-701 American College of Cardiology Foundation.

 

[5] Signs and symptoms of hypercalcemia may include:

o Nausea

o Fatigue

o Vomiting

o Lethargy

o Stomach Pain

o Moodiness

o Constipation

o Irritability

o Anorexia

o Confusion

o Excessive thirst

o Extreme muscle weakness

o Dry mouth or throat

o Irregular heart beat

o Frequent Urination

o Coma

 

[6] Magnes Res. 2008 Jun;21(2):77-82. A connection between magnesium

deficiency and aging: new insights from cellular studies. Killilea DW, Maier

JA.

Nutrition and Metabolism Center, Children's Hospital Oakland Research

Institute.

 

[7] Nutrition Action Healthletter, June, 1993

 

[8] American Journal of Clinical Nutrition, 1995; 61 (4)

 

[9] Osteoporosis International 1993;3(3)

 

[10] Braun, J, Oldendorf, M, Moshage, W, et al. Electron beam computed

tomography in the evaluation of cardiac calcification in chronic dialysis

patients. Am J Kidney Dis 1996; 27:394.

 

[11] Goodman, WG, Goldin, J, Kuizon, BD, et al. Coronary-artery

calcification in young adults with end-stage renal disease who are undergoing

dialysis. N Engl J Med 2000; 342:1478.

 

[12]Arch Intern Med. 2005;165:327-332

 

[13] Eades M, Eades A, The Protein Power Lifeplan, Warner Books, New York,

1999

 

[14] Camara-Martos, F. and M.A. Amaro-Lopez, Influence of Dietary Factors

on Calcium Bioavailability. Biological Trace Element Research, 2002. 89: p.

43-52

 

[15] Jones, G., M. Riley, and T. Dwyer, Maternal Diet during pregnancy is

associated with bone mineral density in children: a longitudinal study.

European Journal of Clinical Nutrition, 2000. 54: p. 749-756

 

[16] Celotti, F. and A. Bignamini, Dietary Calcium and Mineral/Vitamin

Supplementation: a controversial problem. The Journal of International

Research, 1999(27): p. 1-14

 

[17] The source of menstrual cramps may come from eating too much cheese,

yogurt, ice cream or milk, combined with insufficient whole grains and

beans. Or it could come from taking too much calcium without enough magnesium.

Modifying diet and increasing magnesium supplementation may allow menstrual

cramps to disappear.

 

[18] Kaye, P. O'Sullivan, I.The role of magnesium in the emergency

department. Emergency Department, Bristol Royal Infirmary, Bristol, UK Emerg

Med J

2002; 19:288-291

 

[19] Yatzidis H. Successful sodium thiosulphate treatment for recurrent

calcium urolithiasis. Clin Nephrol1985; 23: 63-67

 

[20] Sodium Thiosulfate Treatment for Calcific Uremic Arteriolopathy in

Children and Young Adults. Carlos E. Araya, Robert S. Fennell, Richard E.

Neiberger, and Vikas R. Dharnidharka. Division of Pediatric Nephrology,

Department of Pediatrics, University of Florida College of Medicine,

Gainesville,

Florida. Clin J Am Soc Nephrol 1: 1161-1166, 2006.

_http://cjasn.asnjournals.org/cgi/content/full/1/6/1161_

(http://cjasn.asnjournals.org/cgi/content/full/1/6/1161)

 

 

 

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