Herb Of The Week - Helichrysum - Anti-Inflammatory Properties

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Below is an abstract from a scientific journal about the

anti-inflammatory properties of Helichrysum italicum ...

 

*Smile*

Chris (list mom)

http://www.alittleolfactory.com

 

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http://www.aapspharmaceutica.com/search/view.asp?ID=5238

 

Journal Metadata Search: Pharmaceutical Press - Journal of Pharmacy and

Pharmacology

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Title

 

Anti-inflammatory and antioxidant properties of Helichrysum italicum

 

 

Author(s)

 

Araceli Sala1,María del Carmen Recio2,Rosa María Giner3,Salvador

Máñez4,Horacio Tournier5,Guillermo Schinella6,José-Luis Ríos7,

 

 

Journal

 

Journal of Pharmacy and Pharmacology

 

 

Vol. 54, No. 3, pages 365 (2002)

 

 

ISSN

 

0022-3573

 

 

Publisher

 

Pharmaceutical Press

 

 

Abstract

 

The anti-inflammatory and antioxidant activities of the aerial part of

Helichrysum italicum extracts have been established in various in-vivo

and in-vitro experimental models. The results obtained on the acute

oedemas induced by 12-O-tetradecanoylphorbol 13-acetate (TPA) and ethyl

phenylpropiolate in the mouse ear, by serotonin and phospholipase A2

(PLA2) in the mouse paw, on chronic inflammation induced by repeated

application of TPA in the mouse ear and on the delayed-type

hypersensitivity induced by sheep red blood cells suggest that said

anti-inflammatory activity is due to the effects of compounds expressed

via a corticoid-like mechanism. In addition, the antioxidant activity of

the extracts seems to be implicated in this anti-inflammatory activity,

as the former inhibits enzymatic and non-enzymatic lipid peroxidation

and has free-radical scavenger properties. We conclude that the

anti-inflammatory activity of Helichrysum italicum can be explained by

multiple effects, including inflammatory enzyme inhibition, free-radical

scavenging activity and corticoid-like effects.