Re :Neurotransmitters and Hormones

[Guest guest]

Zev:

 

Did you see Candace Pert in the movie " What the Bleep Do We Know!? " (the original

version.) Also the hardback book by the same title is very good.

 

Anne

-------------- Original message ----------------------

" " <zrosenbe

> While there is minor tissue damage and irritation with needling,

> there doesn't necessarily need to be a pain response to obtaining de

> qi, especially if one follows the Japanese definition of de qi (as I

> do), where it is the practitioner who becomes aware of the qi

> response, not necessarily the patient. I think Candace's work is

> great, I've taken seminars with her, and I think one of the 'secrets'

> of acupuncture is that it works with what I call the 'internal

> pharmacy', the various substances in the body such as

> neurotransmitters and hormones to modify, balance and intensify their

> effects.

>

>

> On Jan 29, 2007, at 1:59 PM, mike Bowser wrote:

>

> >

> > So what about the opioid receptors in the brain

> > (discoved by Candace Pert) and their input into pain response.

> > Do we not elicit a pain when achieving de qi?

> > Hmmh, me thinks that there may be more to this then we think.

> >

> > Mike W. Bowser, L Ac

>

>

>

>

[Guest guest]

Yes, a fun movie. . . .

 

 

On Jan 29, 2007, at 5:35 PM, anne.crowley wrote:

 

> Zev:

>

> Did you see Candace Pert in the movie " What the Bleep Do We

> Know!? " (the original version.) Also the hardback book by the same

> title is very good.

>

> Anne

> -------------- Original message ----------------------

> " " <zrosenbe

> > While there is minor tissue damage and irritation with needling,

> > there doesn't necessarily need to be a pain response to obtaining de

> > qi, especially if one follows the Japanese definition of de qi (as I

> > do), where it is the practitioner who becomes aware of the qi

> > response, not necessarily the patient. I think Candace's work is

> > great, I've taken seminars with her, and I think one of the

> 'secrets'

> > of acupuncture is that it works with what I call the 'internal

> > pharmacy', the various substances in the body such as

> > neurotransmitters and hormones to modify, balance and intensify

> their

> > effects.

> >

> >

> > On Jan 29, 2007, at 1:59 PM, mike Bowser wrote:

> >

> > >

> > > So what about the opioid receptors in the brain

> > > (discoved by Candace Pert) and their input into pain response.

> > > Do we not elicit a pain when achieving de qi?

> > > Hmmh, me thinks that there may be more to this then we think.

> > >

> > > Mike W. Bowser, L Ac

> >

> >

> >

> >

[Guest guest]

Can this also lead to sedation?

I also liked the movie and heard her speak at the local college. Mike W.

Bowser, L Ac

 

 

: zrosenbe:

Mon, 29 Jan 2007 18:44:10 -0800Re: Re :Neurotransmitters and

Hormones

 

 

 

 

Yes, a fun movie. . . .On Jan 29, 2007, at 5:35 PM,

anne.crowley wrote:> Zev:>> Did you see Candace Pert in the movie

" What the Bleep Do We > Know!? " (the original version.) Also the hardback book by

the same > title is very good.>> Anne> -------------- Original message

----------------------> " " <zrosenbe> > While

there is minor tissue damage and irritation with needling,> > there doesn't

necessarily need to be a pain response to obtaining de> > qi, especially if one

follows the Japanese definition of de qi (as I> > do), where it is the

practitioner who becomes aware of the qi> > response, not necessarily the

patient. I think Candace's work is> > great, I've taken seminars with her, and I

think one of the > 'secrets'> > of acupuncture is that it works with what I call

the 'internal> > pharmacy', the various substances in the body such as> >

neurotransmitters and hormones to modify, balance and intensify > their> >

effects.> >> > > > On Jan 29, 2007, at 1:59 PM, mike Bowser

wrote:> >> > >> > > So what about the opioid receptors in the brain> > >

(discoved by Candace Pert) and their input into pain response.> > > Do we not

elicit a pain when achieving de qi?> > > Hmmh, me thinks that there may be more

to this then we think.> > >> > > Mike W. Bowser, L Ac> >> >> >> > [Non-text

portions of this message have been removed]> >>> [Non-text portions of this

message have been removed]>>> [Non-text portions of this message have been

removed]

 

 

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[Guest guest]

Purely speculation at this point.. . and very far from the simple

reality of acupuncture technique (bu/supplementation and xie/drainage).

 

 

On Jan 29, 2007, at 8:57 PM, mike Bowser wrote:

 

> Can this also lead to sedation?

> I also liked the movie and heard her speak at the local college.

> Mike W. Bowser, L Ac

 

 

 

 

[Guest guest]

I have it, would you like to send it by Pando sistem?

Adriana Moiron

 

,_._,___

 

 

 

Atentamente

Dra. Adriana Moiron (Médica Veterinaria)

TE. Móvil: 15-4434-4567 TE.Profesional: 54-011-4658-2750

Bs.As. Argentina

Otros emails: adrianamoiron

http://ar.geocities.com/adrianamoiron

 

 

 

 

 

 

 

 

 

Preguntá. Respondé. Descubrí.

Todo lo que querías saber, y lo que ni imaginabas,

está en Respuestas (Beta).

Probalo ya!

 

 

[Guest guest]

The effects or the translation? So how do you read Bensky's Formula section

that calm the spirit wherein he talks about sedation with herbs? Is this a

mistranslation. Mike W. Bowser, L Ac

 

 

: zrosenbe:

Mon, 29 Jan 2007 21:28:46 -0800Re: Re :Neurotransmitters and

Hormones

 

 

 

 

Purely speculation at this point.. . and very far from the simple reality of

acupuncture technique (bu/supplementation and xie/drainage).On Jan

29, 2007, at 8:57 PM, mike Bowser wrote:> Can this also lead to sedation?> I

also liked the movie and heard her speak at the local college. > Mike W. Bowser,

L Ac

[Guest guest]

Mike,

We are talking about acupuncture here. Without the original

Chinese or pinyin, I cannot comment on what Bensky and Steven Clavey

are referring to as 'sedation'. Give me a specific example from the

text. An shen means to 'calm spirit', a very different technical

issue than 'xie qi' , draining qi from an acupuncture point.

 

 

On Jan 30, 2007, at 6:26 AM, mike Bowser wrote:

 

> The effects or the translation? So how do you read Bensky's Formula

> section

> that calm the spirit wherein he talks about sedation with herbs? Is

> this a

> mistranslation. Mike W. Bowser, L Ac

 

 

 

 

[Guest guest]

Zev,

 

The beginning of chapter 13 in Formulas that calm the spirit, has a mention of

the term sedation. On page 377, " The strategy for treating this type of

disturbance is to sedate and calm the spirit. " I mention this as I consider

that whether by acupuncture or herbs, ancient Chinese used a knowledge based

upon shared concepts. If one wants to argue whether or not the actual word of

xie or sedate was used in acupuncture I might lose that one as I do not read

Chinese, let alone ancient Chinese. But on the other hand, I find it

interesting that the detail or specifics of a word can be taken from a

pictographic language wherein ideas not words were specified. I also would

challenge us to consider that if one were to drain or shunt a channel, the

outcome or result could be sedation. Translations need to include the

vernacular of the times in order to be useful and it seems that sometimes we

choose words that are no longer used. This is a problem that we will continue

to face for some time to come. Mike W. Bowser, L Ac

 

 

: zrosenbe:

Tue, 30 Jan 2007 11:48:09 -0800Re: Re :Neurotransmitters and

Hormones

 

 

 

 

Mike,We are talking about acupuncture here. Without the original Chinese or

pinyin, I cannot comment on what Bensky and Steven Clavey are referring to as

'sedation'. Give me a specific example from the text. An shen means to 'calm

spirit', a very different technical issue than 'xie qi' , draining qi from an

acupuncture point.On Jan 30, 2007, at 6:26 AM, mike Bowser wrote:>

The effects or the translation? So how do you read Bensky's Formula > section>

that calm the spirit wherein he talks about sedation with herbs? Is > this a>

mistranslation. Mike W. Bowser, L Ac[Non-text portions of this message have been

removed]

 

 

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[Guest guest]

Hi Mike

 

mike Bowser <naturaldoc1 wrote:

I also would challenge us to consider that if one were to drain or shunt a

channel, the outcome or result could be sedation. Translations need to include

the vernacular of the times in order to be useful and it seems that sometimes we

choose words that are no longer used.

 

 

 

Doesn't it make sense to have a standard, accurate terminology? Have you read

Nigel's essay? It's very interesting. Page 12 addresses this term directly...

 

http://www.paradigm-pubs.com/resources/refs/wiseman/ration

 

excerpt:

" ‘Sedate’ comes from the Latin Sedare, to ‘cause to sit’, or to ‘seat’, which

is directly related

to the English words ‘sit’, ‘seat’, ‘settle’, and ‘sediment’. ‘Sedate’ implies

a calming or settling action, when applied to the streams of fluid-like qi in

the body, would, logically, result in a slowing down of activity and movement.

The result of a sedating action is precisely the opposite of that of jq xii

stimulus. Thus, to call the stimulus used to treat qi stagnation a ‘sedating’

stimulus suggests a therapeutic mechanism that would aggravate rather than

relieve the condition. "

 

 

Stephen Woodley LAc

 

 

 

[Guest guest]

On the topic of endorphins, Candace Pert and acupuncture,

I wrote a summary of the material in the book, which I hope would entice one

to read or re-read her ground-breaking work...

 

 

 

WISDOM OF THE BODY – MIND, EMOTION AND BODY

 

With CANDACE PERT:

 

 

 

This will be a short synopsis of the lectures from Candace

Pert's book, *Molecules of Emotion*, which lets the public know the gist of

her work from the 70's to the present concerning the " informational

substances " that bind mind and body. Her groundbreaking work in this field

has helped to create the foundation of what is becoming a unified

bio-chemical-physiological theory. This theory connects the nervous systems

with the network of immunity and gastro-intestinal and endocrine functions

within the human body. They are linked in communication with each other

through a lock and key system of receptors and ligands. This receptor

system, she calls the " second nervous system " . It is evolutionarily older,

carries information longer distances than the neuron-axon-dendrite

relationship and may account for ~98% of our bodies thinking processes. Less

than 2% of the body's communication is made through neural synapse. The

whole body and mind paradigm is not one of cause and effect neural

synapsing, but a super-highway of bio-chemical networking.

 

Receptors are proteins made of amino acid chains. Examples of

opiate receptors are endorphins and morphine. Opiate receptors were

discovered by Pert in the early 70's to be located in both the body and

brain. In fact, opiate receptors are found in all vertebrates and some

invertebrates also. Since these endorphins (endogenous morphine) receptors

are crucial to our emotional selves, there may be evidence that humans are

not alone in having feelings. We may all be emotional beings. In humans,

opiate receptors are by far most dense in the frontal lobes of the cerebral

cortex, which interconnects in many ways with the amygdala of the limbic

brain. All norepinephrine in the forebrain comes from the locus coeruleus,

which is the pleasure center of the brain. Drugs such as amphetamine and

cocaine block the reuptake of norepinephrine, increasing the amount that

comes into contact with the receptors. A nodal point is where there is a

high concentration of NPRs (neuropeptide receptors). Points of high-density

convergence are located around where sensory entrances i.e. sight; sound and

smell meet the nervous system. Sensory " highs " come from these endogenous

informational substances. This is expressed as e-motion.

 

Ligands are keys that lock to each receptor, sharing

information. They are specific to each receptor, just as one key will

unlock only one door. There are three chemical types of ligands known. They

are neurotransmitters, steroids and peptides. Neurotransmitters include

acetylcholine, norepinephrine, dopamine, histamine, glycine, GABA, and

serontonin. Previously, it was thought that the autonomic nervous system

was run by acetylcholine and norepinephrine alone. Now it is known that all

the peptides and " informational substances " are located down the spinal

column, facilitating communication between the body and mind through

emotion. The second group of ligands is the steroids, which consist of

testosterone, progesterone, estrogen, and cortisol etc. These start out as

cholesterol and are converted by enzymes.

 

The third and most abundant of ligands in the body (95%) are the peptides.

There are 20 known common amino acids. In chains, they are bound by carbon

and nitrogen to form polypeptides (100+) and proteins (200+). The first

peptide to be discovered was secretin, which acts on the small intestine to

stimulate secretion of pancreatic juices. Another GI hormone, gastrin, is a

small piece of the CCK (cholecystokinin) peptide, carrying messages from the

pancreas to the gall bladder. Later, there was a discovery that pituitary

peptides in the brain, turned out to be in the gut also. These amino acid

chains are manufactured and functioning in several places of the body. Before,

it was thought that the peptides worked in isolation, confined to specific

organs. Pert discovered what others before her intuited, that the mind and

body connect simultaneously. Emphatically, she says, " The body is the

unconscious mind! "

 

Memory, emotion and altered states of consciousness are linked

with neuropeptide interactions. In state-dependant memory recall, it was

found that positive memories are remembered in positive moods. Negative

memories are recalled in instances of negative experiences. Depending on

the circumstance, a receptor-ligand connection will be made according to the

context of the sensory input. This is stored in the receptor-ligand meeting

and will reassociate when faced with similar stimuli. Most memories are

unconscious. Our brain is a filter, remembering on a conscious level, only

what needs to be made conscious. Most of what constitutes reality is

subjective perceiving and remembering. For instance, unconscious become

conscious thought, such as being thirsty, is regulated by a peptide known as

angiotensin. The state of being thirsty is, as Pert calls it, an altered

state of consciousness. In this altered state of consciousness, angiotensin

not only remembers thirst, but also reevaluates it and recreates it as an

emotion. Pert believes that repressed emotions are stored in the body with

the neuropeptide ligands, while memories are in the receptors. The

molecules of emotion are not exactly conscious in themselves, but when met

in a ligand-receptor relationship, sparks fly and communion is made. It's a

sort of chemical love.

 

Central to this theory, is the unification of mind-emotion-body,

as well as more specific systems within. The discovery and advance of the

" informational substances " have given psycho-neuro-immunologists a language

to communicate with. The immune system consists of bone marrow, lymph

nodes, white blood cells and the spleen, which acts as the " brain of the

immune system " . Astonishingly, it has been found that immune system cells

make, store and secrete neuropeptides themselves, such as endorphins. This

feeling and now thinking molecules are in immune cells too, not just the

brain. Viruses, like thieves, use the same receptors as neuropeptides to

enter a cell. Here, we see the importance of emotions in defense, since

some viruses cannot enter through the door when a person is in an elevated

mood. To take an example, the rheovirus, which uses the receptor for

norepinephrine to enter its host, is blocked when there is plenty of

norepinephrine to find its receptor. In times of norepinephrine scarcity

however, as in moments of depression, a rheovirus can pick up on a desperate

norepinephrine receptor much easier, thus opening the lock to the cell's

gate. Furthermore, in cancer trials, it has been discovered that the immune

systems are stronger in those who are expressive, not repressed emotionally.

Emotions are a form of communication, a communication between receptors and

ligands. And open and honest lines of communication seem to be the key to

well being. Without judging these feelings as good or bad, Pert says, " All

honest emotions are positive emotions. "

 

Finally, there is a crucial link between the role of these

" informational substances " in the functioning of the GI system and the

intracellular networking of the entire body. " Gut thought " and " gut

emotion " are often declared. This may be because of the primal role that

the GI has in the overall thinking and feeling of an individual. The

cholecystokinin peptide is involved with both the brain and the GI, as both

the brain and the spleen, " the brain of the immune system " , have receptors

for CCK. CCK governs hunger and satiety. After a meal, the gallbladder,

which is connected by CCK connections with the GI system, receives fat

content from digested food. CCK sends a chemical signal of satisfaction to

the brain, tells the gallbladder to work on the fat and slows the immune

system down. That's why it is so important to be relaxed and feel safe

during and after eating. In the first moment of emotional/mental panic,

there is strong intestinal contraction. Hypothalmic stimulation causes

blood from the GI organs to be rerouted to muscles for a " fight of flight "

kind of reaction. Anger and excitement increase gut motility, while

contentment slows down the process. In slowing down, the parasympathetic ANS

takes the fore and more energy can be used for digestion. Also, since the

immune system is interlaced with GI functioning, it is important to make

peace with one's meal in order to make peace with one's body.

 

In conclusion, Pert eloquently states:

 

As investigations continue, it is becoming increasingly apparent that the

role of peptides is not limited to eliciting simple and singular actions

from individual cell and organ systems. Rather, peptides serve to weave the

body's organs and systems into a single web that reacts to both internal and

external environmental changes with complex, subtly orchestrated responses.

Peptides are the sheet music containing the notes, phrases, and rhythms that

allow the orchestra –your body- to play as an integrated entity. And the

music that results is the tone or feeling that you experience subjectively

as your emotions.

 

(*Molecules*… pg.148)

 

K.

 

On 1/29/07, anne.crowley <anne.crowley wrote:

>

> Zev:

>

> Did you see Candace Pert in the movie " What the Bleep Do We Know!? " (the

> original version.) Also the hardback book by the same title is very good.

>

> Anne

>

> rti