Shehuang Paste on navel + Chinese herbal colon dialysis in refractory cirrhotic ascites

[Guest guest]

Hi All,

 

Colleagues, do YOU know (or can you find out) the ingredients and other

professional data

on Shehuang Gao ( she4-huang2-gao1, Shehuang Paste), as used over the navel in

cirrhotic ascites? Phil was unable to find the ingredients on WWW, including

Chinese sites.

 

Tong GD, Zhou DQ, He JS, Zhang L, Chen ZF, Xiao CL, Peng LS. Clinical research

on

navel application of Shehuang Paste combined with Chinese herbal colon dialysis

in

treatment of refractory cirrhotic ascites complicated with azotemia. World J

Gastroenterol.

2006 Dec 28;12(48):7798-804. Department of Hepatology, Shenzhen Hospital of

Traditional

, Guangzhou University of TCM, Shenzhen 518033, Guangdong

Province,

China. tgd755 AIM: To explore the efficacy and mechanism of a novel

therapeutic method of traditional Chinese medicine in patients with refractory

cirrhotic

ascites complicated with azotemia. METHODS: Seventy-five cases of refractory

cirrhotic

ascites complicated with azotemia were randomly divided into 3 groups:

comprehensive

treatment (n = 29), simple treatment (n = 24), and control (n = 22). The basic

treatment

methods were the same in all groups, including liver protecting medicines,

diuretics and

supportive drugs. The control group underwent only the basic treatment. Shehuang

Paste

(SHP) was applied to the navels of the two treatment groups once a day for 30 d.

Colon

dialysis with Chinese herbs was administered to the comprehensive treatment

group once

every two days. Before and after treatment, we measured abdominal circumference,

BUN,

Cr, serum Na(+), urine Na(+)/K(+), liver function, endotoxin content, NO, and

ET-1. Color

Doppler ultrasonography was conducted to measure the portal vein blood flow.

RESULTS:

The total effective rate for ascites was 72.4% in the comprehensive treatment

group, 45.8%

in the simple treatment, contrasting with 18.2% in the controls. Between the two

treatment

groups and the controls, there were significant differences in the effective

rates (P < 0.01,

and P < 0.05). There was also a significant difference (P < 0.05) between the

two treatment

groups. Measurements of Cr and BUN showed higher values for the treatment

groups, with

the comprehensive better than the simple group (P < 0.05). Sera Na, urine Na/K

were

different, P < 0.01 between pre- and post-treatment in the comprehensive group,

and P <

0.05 in the simple group. The treatment groups' endotoxin content was also

significantly

reduced (P < 0.01, and P < 0.05), with the comprehensive group better than the

simple

group (P < 0.05). Portal vein blood flow and NO content significantly reduced (P

< 0.05), as

did ET-1 content (P < 0.01). There were no significant changes in the control

group (P >

0.05). The comprehensive treatment group's pre- and post-treatment portal vein

and splenic

vein blood flows showed a positive correlation to NO, ET-1 and endotoxin

contents.

CONCLUSION: When treating refractory cirrhotic ascites complicated with

azotemia,

Shehuang Paste combined with Chinese herbal dialysis is better than Shehuang

Paste

alone for ascites resolution, azotemia, and endotoxin elimination. However, both

methods

on their own were also effective for reducing portal and splenic vein blood

flow, and lowering

the contents of NO, ET-1 in the two treatment groups. PMID: 17203523 [PubMed -

in

process]

 

See also: http://scholar.ilib.cn/abstract.aspx?A=zgzyykj200305002 and

http://tinyurl.com/ynbj8m or http://tinyurl.com/yhckr7

 

Best regards,

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HOME + WORK: 1 Esker Lawns, Lucan, Dublin, Ireland

Tel: (H): +353-(0); VOIP Number: +353-1482-7068;

Tel: (M): +353-(0)

 

 

 

 

[Guest guest]

Hi All, & Hi Dr. Tong,

 

Many thanks to Dr. Guang-Dong Tong - senior author of the paper: " Clinical

research on navel application of Shehuang Paste combined with Chinese

herbal colon dialysis in treatment of refractory cirrhotic ascites complicated

with azotemia " by Guang-Dong Tong, Da-Qiao Zhou, Jing-Song He, Lai

Zhang, Zhi-Fei Chen, Chun-Ling Xiao, Li-Sheng Peng World J

Gastroenterol 2006 December 28;12(48):7798-7804; ISSN 1007-9327 CN

14-1219/R] for giving me the links to the full-text of the paper:

 

pdf version: http://www.wjgnet.com/1007-9327/12/7798.pdf

html version: http://www.wjgnet.com/1007-9327/12/7798.asp

 

Shehuang Paste (SHP) Ingredients: Each piece of SHP consisted of snail

flesh (approximately 30g), Moschus 1g , artificial Calculus Bovis 1g, Radix

Euphorbiae Kansui 10g and Bulbus Allii Fistulosi 10g.

 

Preparation: B Allii Fistulosi was pressed juice. Rx Euphorbiae Kansui was

decocted with water twice, at each 2h, and mixed with B Allii Fistulosi juice

that had been filtrated. The mixture of the juice of the 2 herbs was

concentrated to a dense paste with a relative density of 1.20. Moschus and

artificial Calculus Bovis were extracted after being recirculated three times

in 95% ethanol. Snail flesh was minced, the dregs removed and then

stewed. The extract of Moschus and artificial Calculus Bovis, the stewed

snail product and the dense paste were mixed and then formed into a

medicated patch of 3 cm × 3 cm in size (undertaken by the Pharmaceutical

Department of Shenzhen Hospital, affiliated to Guangzhou University of

TCM, batch No: 030113)[12]. The patch was placed into a bag and stored at

4°C.

 

Quality control: Quality control for the SHP was by detecting the content of

Kotone musk and Bilirubin, the main ingredients of Moschus and artificial

Calculus Bovis. Moschus (Batch No: 030912) and artificial Calculus Bovis

(Batch No: 031221) were purchased from Shenzhen Branch of the

Medicinal Material Company of China. The amount of medicinal paste on

each patch was 1.2 g/100 cm2. Bilirubin content in Calculus Bovis was

above 41% (Bilirubin content is noted as being 35% in the 2005 edition of

Pharmacopeia of China ). Ketone musk in each piece of SHP was 2.73

mg/g[13] measured by high performance liquid chromatograph (Gillson,

France). The method is reliable and stable.

 

Colon dialysis ingredients: The formula used for colon dialysis consisted of

Rheum Palmatum L, Sophorage Japonica L, Lonicera Japonica Thunb,

Taraxcum mongolicum, Herba-Mazz, and Ostrea telienwhanensis Crosse;

30 g of each.

 

Preparation: All ingredients in the colon dialysis formula were decocted

together twice in a routine way. The 2 juices were mixed, filtrated to 200 ml,

and stored at -70°C until use. For use, the mixture was warmed to 38°C

(carried out by the Preparation Room, Guangzhou University of Traditional

affiliated Shenzhen Hospital, No. 030113).

 

Colleagues, what is the official Chinese name for SNAIL FLESH? Have you

professional details of its LAtin name, " Herb Class " , main actions, uses,

dosage, etc?

 

Best regards,

 

 

 

 

[Guest guest]

Hi All, & Hi Dr. Tong,

 

Many thanks to Dr. Guang-Dong Tong - senior author of the paper: " Clinical

research on navel application of Shehuang Paste combined with Chinese

herbal colon dialysis in treatment of refractory cirrhotic ascites complicated

with azotemia " by Guang-Dong Tong, Da-Qiao Zhou, Jing-Song He, Lai

Zhang, Zhi-Fei Chen, Chun-Ling Xiao, Li-Sheng Peng World J

Gastroenterol 2006 December 28;12(48):7798-7804; ISSN 1007-9327 CN

14-1219/R] for giving me the links to the full-text of the paper:

 

pdf version: http://www.wjgnet.com/1007-9327/12/7798.pdf

html version: http://www.wjgnet.com/1007-9327/12/7798.asp

 

Shehuang Paste (SHP) Ingredients: Each piece of SHP consisted of snail

flesh (approximately 30g), Moschus 1g , artificial Calculus Bovis 1g, Radix

Euphorbiae Kansui 10g and Bulbus Allii Fistulosi 10g.

 

Preparation: B Allii Fistulosi was pressed juice. Rx Euphorbiae Kansui was

decocted with water twice, at each 2h, and mixed with B Allii Fistulosi juice

that had been filtrated. The mixture of the juice of the 2 herbs was

concentrated to a dense paste with a relative density of 1.20. Moschus and

artificial Calculus Bovis were extracted after being recirculated three times

in 95% ethanol. Snail flesh was minced, the dregs removed and then

stewed. The extract of Moschus and artificial Calculus Bovis, the stewed

snail product and the dense paste were mixed and then formed into a

medicated patch of 3 cm × 3 cm in size (undertaken by the Pharmaceutical

Department of Shenzhen Hospital, affiliated to Guangzhou University of

TCM, batch No: 030113)[12]. The patch was placed into a bag and stored at

4°C.

 

Quality control: Quality control for the SHP was by detecting the content of

Kotone musk and Bilirubin, the main ingredients of Moschus and artificial

Calculus Bovis. Moschus (Batch No: 030912) and artificial Calculus Bovis

(Batch No: 031221) were purchased from Shenzhen Branch of the

Medicinal Material Company of China. The amount of medicinal paste on

each patch was 1.2 g/100 cm2. Bilirubin content in Calculus Bovis was

above 41% (Bilirubin content is noted as being 35% in the 2005 edition of

Pharmacopeia of China ). Ketone musk in each piece of SHP was 2.73

mg/g[13] measured by high performance liquid chromatograph (Gillson,

France). The method is reliable and stable.

 

Colon dialysis ingredients: The formula used for colon dialysis consisted of

Rheum Palmatum L, Sophorage Japonica L, Lonicera Japonica Thunb,

Taraxcum mongolicum, Herba-Mazz, and Ostrea telienwhanensis Crosse;

30 g of each.

 

Preparation: All ingredients in the colon dialysis formula were decocted

together twice in a routine way. The 2 juices were mixed, filtrated to 200 ml,

and stored at -70°C until use. For use, the mixture was warmed to 38°C

(carried out by the Preparation Room, Guangzhou University of Traditional

affiliated Shenzhen Hospital, No. 030113).

 

Colleagues, what is the official Chinese name for SNAIL FLESH? Have you

professional details of its LAtin name, " Herb Class " , main actions, uses,

dosage, etc?

 

Best regards,