Herbal ingredients in QFGJS (Qing-Fu-Guan-Jie-Shu)

[Guest guest]

Hi All,

 

Do you know the herbal ingredients in QFGJS (Qing-Fu-Guan-Jie-Shu). I

cannot find them on WWW.

 

Cai X, Zhou H, Wong YF, Xie Y, Liu ZQ, Jiang ZH, Bian ZX, Xu HX, Liu L.

Suppression of the onset and progression of collagen-induced arthritis in

rats by QFGJS, a preparation from an anti-arthritic Chinese herbal formula.

J Ethnopharmacol. 2006 Sep 16; [Epub ahead of print] Research and

Development Division, School of , Hong Kong Baptist

University, Kowloon Tong, Kowloon, Hong Kong, China. QFGJS (Qing-Fu-

Guan-Jie-Shu) is an herbal preparation, and its pronounced effectiveness in

treating adjuvant-induced arthritis (AIA) has been previously demonstrated.

We herein aimed to confirm its anti-arthritic effect on collagen-induced

arthritis (CIA) in rats. CIA was established in female Wistar rats with

intradermal injection of type II bovine collagen at the base of the tail of

animals. CIA rats were treated daily with oral administration of different

doses of QFGJS beginning on the day of the induction of arthritis (day 0,

the prophylactic treatment) or on the day after the onset of arthritis (day

13, the therapeutic treatment) until day 30. The results showed that

prophylactic treatment with QFGJS significantly suppressed the onset of

arthritis, and therapeutic treatment with QFGJS markedly reduced paw

swelling and ESR levels even in the established CIA. Radiologic and

histopathologic changes in the arthritic joints were also significantly

reduced in the QFGJS-treated versus vehicle-treated rats. Moreover, the

serum levels of pro-inflammatory cytokines TNF-alpha, IL-1beta, and IL-6

were markedly lowered in the QFGJS-treated rats. Hence, our studies

demonstrate the quality, safety, and effectiveness of QFGJS as an anti-

arthritic agent, which makes QFGJS a strong candidate for further clinical

trials on rheumatoid arthritis (RA) patients. PMID: 17049776 [PubMed - as

supplied by publisher]

 

Best regards,