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Here is the info I received from herbal-healing (AT) googl (DOT) com regarding

persimmon leaf.

 

Cory Trusty

http://chinesetherapeutics.org

 

---------- Forwarded message ----------

Fri, 4 Aug 2006 14:51:39 -0700 (PDT)

Laura Sirecci <lsireci

Herbal-Healing (AT) googl (DOT) com

 

Cory,

Here's what I found online:

1)This first article costs money to buy the full thing, but I copied for you

what was available of it. The link to it is at the bottom of the article.

 

British Journal of Dermatology

Volume 146 Page 221 - February 2002

doi:10.1046/j.1365-2133.2002.04557.x

Volume 146 Issue 2 Cutaneous Biology Oral administration of

persimmon leaf extract ameliorates skin symptoms and transepidermal water loss

in atopic dermatitis model mice, NC/Nga M.Matsumoto, M.Kotani, A.Fujita,

S.Higa * T.Kishimoto * M.Suemura* and T.Tanaka*

Background We have previously shown that persimmon leaf extract and its

major flavonoid constituent, astragalin, inhibited histamine release by

basophils and that oral administration of these substances prior to the onset

into an atopic dermatitis (AD) model mouse, NC/Nga, prevented development of

dermatitis.

Objectives This study was designed to assess the clinical therapeutic effect

of persimmon leaf extract and astragalin in NC/Nga mice suffering from

dermatitis and the dose–response preventive effects of persimmon leaf extract on

dermatitis and transepidermal water loss (TEWL).

Methods The efficacy of persimmon leaf extract or astragalin in NC/Nga mice

was judged by measurement of skin severity, scratching behaviour, serum IgE

levels or TEWL.

Results Oral administration of persimmon leaf extract (250 mg kg1) or

astragalin (1·5 mg kg1) for 4 weeks into NC/Nga mice with overt dermatitis

resulted in a decrease in the severity of the condition. The preventive effect

of persimmon leaf extract on the dermatitis was dose-dependent and continuous

intake of persimmon leaf extract significantly decreased its onset and

development. In addition, TEWL was also suppressed at a persimmon leaf extract

dose of 250 mg kg1. No significant adverse reaction by these substances could be

observed.

Conclusions These observations suggest that persimmon leaf extract or the

flavonoid astragalin may be alternative substances for the management of AD.

Link:

http://www.blackwell-synergy.com/links/doi/10.1046/j.1365-2133.2002.04557.x/abs/

 

 

2)Article: Dried green leaf powders of Jew's mellow (Corchorus), persimmon

(Diosphyros kaki) and sweet potato (Ipomoea batatas poir) lower hepatic

cholesterol concentration and increase fecal bile acid excretion in rats fed a

cholesterol-free diet.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=9\

839835 & dopt=Abstract

 

3)

72A-10 ANTIOXIDATIVE SUBSTANCES AND ACTIVITY OF THE LEAVES OF

PERSIMMON(DIOSPYROS KAKI) CULTIVARS by S.W. CHOI, J.H. Kim, T.Y. Ha1 & H.K. No2

Dept. Food Sci. & Nutr., Catholic University Of Taegu-Hyosung, Hayang 712-702,

KOREA

Persimmon leaves, which are a good source of important dietary antioxidants,

such as vitamin A & C, and flavonoids, have been widely used as a tea in

oriental countries. In particular, several tannins and flavonoids isolated from

persimmon leaf were recently found to have antihypertensive, anticarcinogenic,

and antimutagenic actions. It is highly possible, therefore, that persimmon

leaves may be developed into potential sources of natural antioxidants and

therapeutic drugs. We have selected persimmon cultivar suitable for

manufacturing persimmon leaf tea, through the experimental methods described

below. Our objectives were to determine the levels of antioxidative substances

in thirteen different cultivars of persimmon leaf during growth, and further to

investigate their antioxidative activities. The antioxidative substances of

persimmon leaves were quantified by using HPLC, and the antioxidative activities

of their methanol extracts were evaluated by using rat liver

microsomal lipid peroxidation induced by 2,2'-azobis(2-amidino -propane)

dihydrochloride(AAPH) and FeSO4/H2O2. The total soluble phenol, L-ascorbic

acid and flavonoid contents of astringent persimmon leaves were higher than

those of nonastringent persimmon leaves, although thier contents vary

considerably with cultivar and growth. " Kojongsi " and " Bansi " persimmon leaves

harvested at the early stage of growth(6/4) had greater total souble phenol,

L-ascorbic acid and flavonoid contents, and antioxidant activities than other

persimmon leaves. Fermented persimmon leaves had lower the L-ascorbic acid and

flavonoid contents, and especially a greater reductions were detected in steamed

persimmon leaves and dried persimmon leaves. These results suggest that

astringent persimmon leaves may be useful as potential sources of natural

antioxidants. In particular, " Kojongsi " and " Bansi " persimmon leaves harvested

at the early stage of growth can be used as a source of persimmon leaf

tea.

Link: http://ift.confex.com/ift/98annual/techprogram/accepted/1095.htm

 

4)

Title: Deodorant composition Document Type and Number: United

States Patent 6139842 Link to this Page:

http://www.freepatentsonline.com/6139842.html Abstract: A deodorant

composition comprises persimmon fruit juice and an aqueous extract of persimmon

leaves in a liquid or solid concentrate form. The composition optionally

contains a non-toxic, excipient such as dextrin.

 

 

5)This site refereces it as a natural Vitam C supplement.

http://kjmaloe.en.ec21.com/GC00485608/CA00485616/Persimon_Leaf_Tea.html

 

6)This one refers to it as an itching remedy:

http://www.patentstorm.us/patents/6863907.html

 

Hope this helps.

Laura

 

 

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