Guest guest Posted August 6, 2006 Report Share Posted August 6, 2006 Here is the info I received from herbal-healing (AT) googl (DOT) com regarding persimmon leaf. Cory Trusty http://chinesetherapeutics.org ---------- Forwarded message ---------- Fri, 4 Aug 2006 14:51:39 -0700 (PDT) Laura Sirecci <lsireci Herbal-Healing (AT) googl (DOT) com Cory, Here's what I found online: 1)This first article costs money to buy the full thing, but I copied for you what was available of it. The link to it is at the bottom of the article. British Journal of Dermatology Volume 146 Page 221 - February 2002 doi:10.1046/j.1365-2133.2002.04557.x Volume 146 Issue 2 Cutaneous Biology Oral administration of persimmon leaf extract ameliorates skin symptoms and transepidermal water loss in atopic dermatitis model mice, NC/Nga M.Matsumoto, M.Kotani, A.Fujita, S.Higa * T.Kishimoto * M.Suemura* and T.Tanaka* Background We have previously shown that persimmon leaf extract and its major flavonoid constituent, astragalin, inhibited histamine release by basophils and that oral administration of these substances prior to the onset into an atopic dermatitis (AD) model mouse, NC/Nga, prevented development of dermatitis. Objectives This study was designed to assess the clinical therapeutic effect of persimmon leaf extract and astragalin in NC/Nga mice suffering from dermatitis and the dose–response preventive effects of persimmon leaf extract on dermatitis and transepidermal water loss (TEWL). Methods The efficacy of persimmon leaf extract or astragalin in NC/Nga mice was judged by measurement of skin severity, scratching behaviour, serum IgE levels or TEWL. Results Oral administration of persimmon leaf extract (250 mg kg1) or astragalin (1·5 mg kg1) for 4 weeks into NC/Nga mice with overt dermatitis resulted in a decrease in the severity of the condition. The preventive effect of persimmon leaf extract on the dermatitis was dose-dependent and continuous intake of persimmon leaf extract significantly decreased its onset and development. In addition, TEWL was also suppressed at a persimmon leaf extract dose of 250 mg kg1. No significant adverse reaction by these substances could be observed. Conclusions These observations suggest that persimmon leaf extract or the flavonoid astragalin may be alternative substances for the management of AD. Link: http://www.blackwell-synergy.com/links/doi/10.1046/j.1365-2133.2002.04557.x/abs/ 2)Article: Dried green leaf powders of Jew's mellow (Corchorus), persimmon (Diosphyros kaki) and sweet potato (Ipomoea batatas poir) lower hepatic cholesterol concentration and increase fecal bile acid excretion in rats fed a cholesterol-free diet. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=9\ 839835 & dopt=Abstract 3) 72A-10 ANTIOXIDATIVE SUBSTANCES AND ACTIVITY OF THE LEAVES OF PERSIMMON(DIOSPYROS KAKI) CULTIVARS by S.W. CHOI, J.H. Kim, T.Y. Ha1 & H.K. No2 Dept. Food Sci. & Nutr., Catholic University Of Taegu-Hyosung, Hayang 712-702, KOREA Persimmon leaves, which are a good source of important dietary antioxidants, such as vitamin A & C, and flavonoids, have been widely used as a tea in oriental countries. In particular, several tannins and flavonoids isolated from persimmon leaf were recently found to have antihypertensive, anticarcinogenic, and antimutagenic actions. It is highly possible, therefore, that persimmon leaves may be developed into potential sources of natural antioxidants and therapeutic drugs. We have selected persimmon cultivar suitable for manufacturing persimmon leaf tea, through the experimental methods described below. Our objectives were to determine the levels of antioxidative substances in thirteen different cultivars of persimmon leaf during growth, and further to investigate their antioxidative activities. The antioxidative substances of persimmon leaves were quantified by using HPLC, and the antioxidative activities of their methanol extracts were evaluated by using rat liver microsomal lipid peroxidation induced by 2,2'-azobis(2-amidino -propane) dihydrochloride(AAPH) and FeSO4/H2O2. The total soluble phenol, L-ascorbic acid and flavonoid contents of astringent persimmon leaves were higher than those of nonastringent persimmon leaves, although thier contents vary considerably with cultivar and growth. " Kojongsi " and " Bansi " persimmon leaves harvested at the early stage of growth(6/4) had greater total souble phenol, L-ascorbic acid and flavonoid contents, and antioxidant activities than other persimmon leaves. Fermented persimmon leaves had lower the L-ascorbic acid and flavonoid contents, and especially a greater reductions were detected in steamed persimmon leaves and dried persimmon leaves. These results suggest that astringent persimmon leaves may be useful as potential sources of natural antioxidants. In particular, " Kojongsi " and " Bansi " persimmon leaves harvested at the early stage of growth can be used as a source of persimmon leaf tea. Link: http://ift.confex.com/ift/98annual/techprogram/accepted/1095.htm 4) Title: Deodorant composition Document Type and Number: United States Patent 6139842 Link to this Page: http://www.freepatentsonline.com/6139842.html Abstract: A deodorant composition comprises persimmon fruit juice and an aqueous extract of persimmon leaves in a liquid or solid concentrate form. The composition optionally contains a non-toxic, excipient such as dextrin. 5)This site refereces it as a natural Vitam C supplement. http://kjmaloe.en.ec21.com/GC00485608/CA00485616/Persimon_Leaf_Tea.html 6)This one refers to it as an itching remedy: http://www.patentstorm.us/patents/6863907.html Hope this helps. Laura Quote Link to comment Share on other sites More sharing options...
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