Sweeter than Sweet;Saltier than Salt: More Sour than an Aborted Fetus

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i4crob

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BettyM19

Wed, 30 Apr 2008 19:22:57 -0400

 

 

Sweeter than Sweet; Saltier than Salt; More Sour than an Aborted Fetus

 

Sugar, ahhh - - honey honey

you are my candy girl

and you got me wanting you

I just can't believe the loveliness of loving you

(I just can't believe its true)

I just can believe the wonder of this feeling too

(I just can't believe its true)

--Wilson Pickett, 1970 (Written by Barry and Andy Kim)

 

We are witnessing the dawning of a sci-fi food revolution.

A new technology. A new food group. Amazingly, my research

uncovered something nobody has ever revealed before in a column,

newspaper article, or magazine expose. The next time you read

"artificial flavor" on a food label, you should be aware that

a component of that new genetically engineered food additive

may be embryonic kidney cells from aborted human fetuses.

 

The new high-tech artificial flavors are not flavors at all.

Instead, they contain chemicals which have been engineered

to fool human taste buds. Future foods will need no salt, sugar,

MSG, or artificial sweeteners. Instead, sensory perceptions will

become warped by modern science. Brains will taste things that

are not really there. Illusions. Deceptions. Memories of taste

which are now artificially induced.

 

You may not understand the abstract of the most recent publication

from this new food science, as published in the May 2, 2008 issue

of the Journal of Biochemistry. I will translate.

 

The Abstract:

 

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J Biol Chem. 2008 May 2;283(18):11981-94.

Small molecule activator of the human epithelial sodium

channel.Lu M, Echeverri F, Kalabat D, Laita B, Dahan DS,

Smith RD, Xu H, Staszewski L, Yamamoto J, Ling J, Hwang N,

Kimmich R, Li P, Patron E, Keung W, Patron A, Moyer BD.

Senomyx, Inc., San Diego, California 92121.

 

The epithelial sodium channel (ENaC), a heterotrimeric complex

composed of alpha, beta, and gamma subunits, belongs to the

ENaC/degenerin family of ion channels and forms the principal

route for apical Na(+) entry in many reabsorbing epithelia.

 

Although high affinity ENaC blockers, including amiloride and

derivatives, have been described, potent and specific small

molecule ENaC activators have not been reported. Here we

describe compound S3969 that fully and reversibly activates

human ENaC (hENaC) in an amiloride-sensitive and dose-dependent

manner in heterologous cells. Mechanistically, S3969 increases

hENaC open probability through interactions requiring the

extracellular domain of the beta subunit. hENaC activation by

S3969 did not require cleavage by the furin protease, indicating

that nonproteolyzed channels can be opened. Function of

alphabetaG37Sgamma hENaC, a channel defective in gating that

leads to the salt-wasting disease pseudohypoaldosteronism type I,

was rescued by S3969. Small molecule activation of hENaC may find

application in alleviating human disease, including

pseudohypoaldosteronism type I, hypotension, and neonatal

respiratory distress syndrome, when improved Na(+) flux across

epithelial membranes is clinically desirable.

 

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OK, so what does it all mean? Another question:

 

What's $6 today and $100 in the Near Future?

 

One share of stock from a company called Senomyx.

SNMX trades on NASDAQ

 

http://www.senomyx.com

 

From the Senomyx website:

 

"Flavors are substances that impart tastes or aromas in

foods and beverages. Individuals experience the sensation

of taste when flavors in food and beverage products interact

with taste receptors in the mouth...signals are sent to the

brain where a specific taste sensation is registered.

 

We have discovered or in-licensed many of the key receptors

that mediate taste in humans. Having isolated human taste

receptors, we have created proprietary taste receptor-based

assay systems...has enabled us to improve our ability to

find novel flavor enhancers...As a result, we have synthesized

and discovered hundreds of unique potential flavor enhancers and

taste modulators."

 

Translation: Senomyx is re-inventing food and flavor by genetically

engineering taste bud receptor cell triggers. Foods of the future

will contain "flavor enhancers" which fool human taste buds into

perceiving the sensations of sweetness, sourness, saltiness, and

bitterness.

 

Remember the artificial sweetener controversies? Chemical

sugar-replicating compounds are listed on food labels. The

new chemicals made by biotech companies will require no

such labels. Although they are not actual flavors, they will

be called "artificial flavors."

 

How did Senomyx accomplish the task? A (multi-hour) review of

their patents reveals that it all began with the cloning of

human embryonic kidney cells. Step two was a recombinant

process involving the combination of genetic material from

embryonic kidney cells and human adeno-virus. If I had the

ability to recall ten thousand abbreviations for the amino

acid sequence, plus hundreds of complex combinations of

ACTG (adeneine, cytosine, thymine, guanine) I'd describe the

structure to you. For those curious scientists, do a google

search with the keywords 'Senomyx and patents' and the

third link (bioportfolio.com) will provide more info than you

need to know. See: United States Patent #5,993,778.

 

How far into the future will these new biotech wonders appear

in our food supply?

 

The future is now. The next time you read "artificial flavor"

on a food label, pause to consider what you've read here today.

Content labels should read: Embryonic kidney cells from

aborted human fetuses.

 

Senomyx is presently developing new products with many of

the world's largest food manufacturers including Campbell's

and Coca Cola. In fact, if you eat Nestle's foods, your

taste buds are being artificially stimulated by biotech

products developed by Senomyx. You may now know what you

are eating, but I take this opportunity to paraphrase 17th

century author Miguel Cervantes, who wrote in Don Quixote:

 

"The proof is in the pudding."

 

Robert Cohen

http://www.notmilk.com