Guest guest Posted April 1, 2009 Report Share Posted April 1, 2009 Statins what you should know : First, that they work about 30% less in real life than what was found in trials. Statins do not meet expectations for lowering low-density lipoprotein cholesterol levels when used in clinical practice. Department of Preventive Cardiology, The Cleveland Clinic Foundation, Cleveland, Ohio One of the side effects of statin could be myositis, a chronic or persistent muscle inflammation (including your heart, of course). Statin and statin-fibrate use was significantly associated with increased myositis risk in a managed care population. What they should have told you: “In a direct comparison between diet with cholesterol lowering food versus statin, it was found that the results in lowering bad cholesterol was similar in the diet group and in the statin group and this after only four weeks, the Food rich in plant sterols used in this study were 1.0 g/1000 kcal, soy-protein foods (including soy milks and soy burgers, 21.4 g/1000 kcal, almonds 14 g/1000 kcal, and viscous fibers from oats, barley, psyllium, and the vegetables okra and eggplant.†Direct comparison of a dietary portfolio of cholesterol-lowering foods with a statin in hypercholesterolemic participants. Clinical Nutrition and Risk Factor Modification Center, St Michael’s Hospital, Toronto, Canada. Statins do not provide benefit for people with diabetes either. (1) (2) (3)For comparison, an observational study reported that if 250 sedentary diabetic patients were to become physically active, four times as many lives will be saved. (4) (1) Sever PS, op. cit.. (2)12 Shepherd J, op.cit. (3)The ALLHAT Officerrs and Coordinators for the ALLHAT Collaborative Research Group. Major Outcomes in Moderately Hypercholesterolemic, Hypertensive Patients Randomized to Pravastatin vs UsualCare ..Journal of the American Medical Association. 2002;288:2998-3007. (4) Gregg EW, Gerzoff RB, Caspersen CJ, et al. Relationship of Walking to Mortality Among US Adults with Diabetes. Archives of Internal Medicine. 2003;163:1440-1447. ========================================= Statins & Nerve Damage Statins can create a peripheral nerve disorder with the following symptoms: Numbness Pain Burning or tingling Muscle weakness Sensitivity to touch Statin induced neuropathy: myth or reality? Formaglio M, Vial C. Service ENMG et Pathologies Neuromusculaires, Hôpital Neurologique “It is thought that as many as 25% of statin users who exercise, may experience muscle fatigue, weakness, aches, and cramping due to statin.†Statin-induced apoptosis and skeletal myopathy. Am J Physiol Cell Physiol. 2006 Dec;291(6):C1208-12. Epub 2006 Aug 2. ============================================================ What They Should Tell You: “Statins are immune system suppressors and kill Helper T-cells.†Statin is an Immune system suppressor: “This unexpected effect provides a scientific rationale for using statins as immunosuppressors, not only in organ transplantation, but in numerous other conditions as well,†according to lead author Dr. Brenda Kwak, of the Foundation for Medical Research in Geneva, Switzerland, and colleagues. The concentrations of the drugs were very similar to doses used in patients. Nature Medicine 2000;6:1311-1312, 1399-1402. --------------------------- Lipid-Lowering Drugs and Cancer n a review of the scientific research on the carcinogenicity of the members of the two most popular classes of lipid-lowering drugs (the fibrates and the statins) it was Found That All Cause Cancer In Rodents.Conclusion of the study: “The results of experiments in animals and humans suggest that lipid-lowering drug treatment, especially with the fibrates and statins, should be avoided except in patients at high short-term risk of coronary heart disease.†Newman TB, Hulley SB.Department of Laboratory Medicine, School of Medicine, University of California, San Francisco “How did it happen that cholesterol-lowering agents were approved by the FDA for long-term use in spite of their animal carcinogenicity?†Thomas B. Newman, MD, MPH, Stephan B. Hulley, MD, MPH in their research on Carcinogenicity of Lipid-Lowering Drugs went to dig in the minutes of the Endocrinologic and Metabolic Drugs Advisory Committee meetings (under the Freedom of Information Act) during the discussion for the approbation of the drug gemfibrozil (October 17, 1988) What they found is beyond imagination and left me speechless. “Dr. Gloria Troendle (deputy director, Division of Metabolism and Endocrine Drug Products for the FDA) noted that gemfibrozil belongs to a class of drugs that has been shown to increase total mortality. It has been shown to have animal carcinogenicity and she does not believe the FDA has ever approved a drug for long-term prophylactic use that was carcinogenic at such low multiples of the human dose as gemfibrozil?â€To make a long story short, only three of the nine members of the advisory committee believed that the benefit of gemfibrozil outweighs the risk. The FDA ignored the committee’s recommendation and granted approval to the drug gemfibrozil. Under the Health Sentinel you will find a section on the FDA that will give you a better idea of what they’re all bout. You can find all the information at: http://www.captainclark.com/Pages/jamareport.html ======================================================= What They Should Tell You Urgently about statins and coenzymeQ10 CQ10 is an antioxidant which protects he energy-producing parts of a cell (mitochondria) from toxic substances.Statins deplete coenzyme Q10 from your muscles and from your blood.Even worse, it blocks the biosynthesis of coenzyme CoQ10. You can actually lose up to 50% of your CoQ10. Your heart is the muscle that consumes and needs Q10 the most in order to function. Coenzyme Q (10) and statins: Biochemical and clinical implications. Littarru GP, Langsjoen P. Institute of Biochemistry, Polytechnic University of the Marche, Via Ranieri, 60131 Ancona, Italy In patients with pre-existing congestive heart failure, the addition of statin therapy causes a decrease in blood CoQ10 levels and a decline in myocardial function. Folkers K., Langsjoen P., Willis R., Richardson P., Xia L., et al. Lovastatin decreases coenzyme Q levels in humans. Proc. Nat Acad. Sci. USA. 87: 8931-8934, 1990 CoQ10 is essential for the health of your heart. This is an antioxidant used by Alternative Medicine practitioners to fight CHD on a daily basis. In a healthy heart there is more CoQ10 than in any other muscle of the body. Folkers K, Littarru GP, Ho L, Runge TM, Havanonda S, Cooley D. Evidence for a deficiency of coenzyme Q10 in human heart disease. Int Z vitaminforsch 1970; 4(3):380-390. A Silent Killer? tip_icon The researchers at Ghirlanda reported in a double-bind, placebo-controlled study a decrease of 50-54% of CoQ10 levels in the statin treatment groups, (1) and similar results were reproduced by Watts. (2) (1) Ghirlanda G, Oradei A, Manto A, Lippa S, Uccioli L, Caputo S, Greco AV, Littarru GP. Evidence of plasma CoQ10-lowering effect by HMG-CoA reductase inhibitors: a double-blind, placebo-controlled study. J Clin Pharmacol. 1993.Mar;33(3):226-229 (2) Watts GF, Castelluccio C, Rice-Evans C, Taub NA, Baum H, Quinn PJ. Plasma coenzyme Q (ubiquinone) concentrations in patients treated with simvastatin. J Clin Pathol. Nov 1993;46(11):1055-1057. Could It Be Dangerous? Canada insisted on warning labels for the need for supplemental CoQ10 to be placed on every statin prescription. Before taking a statin, patients should tell their doctor or pharmacist if they: • Are pregnant, intend to become pregnant, are breast-feeding or intend to breast-feed. • Have thyroid problems. • Regularly drink three or more alcoholic drinks daily. • Are taking other cholesterol lowering medication such as fibrates (gemfibrozil, fenofibrate) or niacin. • Are taking other medications, including prescription, non-prescription and natural health products, as drug interactions are possible. • Have a family history of muscular disorders. • Had any past problems with their muscles (pain, tenderness), after using a statin. • Have kidney or liver problems. • Have diabetes. • Have undergone surgery or other tissue injury. • Do excessive physical exercise. Health Canada advises consumers about important safety information on statins ============================================= Sorry for the length of this article this only part of the iceberg see: http://www.jmbblog.com/coronary-heart-disease-best-kept-secrets-part-3-drugs/ 95 % of CHD can be reversed with a couple of supplements and nutrition . I forgot.. from a recent research : statins increase the risk of heart attacks. John Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 3, 2009 Report Share Posted April 3, 2009 I see that I had better supplement with Coq10 & get off the statins. Thank you so much. Fantastic info. , shaman urban <shaman_urban wrote: > > > Statins what you should know : > > First, that they work about 30% less in real life than what was found in trials. Statins do not meet expectations for lowering low-density lipoprotein cholesterol levels when used in clinical practice. > Department of Preventive Cardiology, The Cleveland Clinic Foundation, Cleveland, Ohio > > > One of the side effects of statin could be myositis, a chronic or persistent muscle inflammation (including your heart, of course). Statin and statin-fibrate use was significantly associated with increased myositis risk in a managed care population. > > What they should have told you: > > “In a direct comparison between diet with cholesterol lowering food versus statin, it was found that the results in lowering bad cholesterol was similar in the diet group and in the statin group and this after only four weeks, the Food rich in plant sterols used in this study were 1.0 g/1000 kcal, soy-protein foods (including soy milks and soy burgers, 21.4 g/1000 kcal, almonds 14 g/1000 kcal, and viscous fibers from oats, barley, psyllium, and the vegetables okra and eggplant.†> > Direct comparison of a dietary portfolio of cholesterol-lowering foods with a statin in hypercholesterolemic participants. Clinical Nutrition and Risk Factor Modification Center, St Michael’s Hospital, Toronto, Canada. > > > Statins do not provide benefit for people with diabetes either. (1) (2) (3)For comparison, an observational study reported that if 250 sedentary diabetic patients were to become physically active, four times as many lives will be saved. (4) > (1) Sever PS, op. cit.. (2)12 Shepherd J, op.cit. > (3)The ALLHAT Officerrs and Coordinators for the ALLHAT Collaborative Research Group. Major > Outcomes in Moderately Hypercholesterolemic, Hypertensive Patients Randomized to Pravastatin vs UsualCare > .Journal of the American Medical Association. 2002;288:2998-3007. > (4) Gregg EW, Gerzoff RB, Caspersen CJ, et al. Relationship of Walking to Mortality Among US Adults > with Diabetes. Archives of Internal Medicine. 2003;163:1440-1447. > > > ========================================= > > Statins & Nerve Damage > > Statins can create a peripheral nerve disorder with the following symptoms: > > Numbness > Pain > Burning or tingling > Muscle weakness > Sensitivity to touch > Statin induced neuropathy: myth or reality? Formaglio M, Vial C. > Service ENMG et Pathologies Neuromusculaires, Hôpital Neurologique > > “It is thought that as many as 25% of statin users who exercise, may experience muscle fatigue, weakness, aches, and cramping due to statin.†> Statin-induced apoptosis and skeletal myopathy. Am J Physiol Cell Physiol. 2006 Dec;291(6):C1208-12. Epub 2006 Aug 2. > > ============================================================ > > What They Should Tell You: > > “Statins are immune system suppressors and kill Helper T-cells.†> > Statin is an Immune system suppressor: “This unexpected effect provides a scientific rationale for using statins as immunosuppressors, not only in organ transplantation, but in numerous other conditions as well,†according to lead author Dr. Brenda Kwak, of the Foundation for Medical Research in Geneva, Switzerland, and colleagues. The concentrations of the drugs were very similar to doses used in patients. > > Nature Medicine 2000;6:1311-1312, 1399-1402. > --------------------------- > Lipid-Lowering Drugs and Cancer > > n a review of the scientific research on the carcinogenicity of the members of the two most popular classes of lipid-lowering drugs (the fibrates and the statins) it was Found That All Cause Cancer In Rodents.Conclusion of the study: “The results of experiments in animals and humans suggest that lipid-lowering drug treatment, especially with the fibrates and statins, should be avoided except in patients at high short-term risk of coronary heart disease.†> Newman TB, Hulley SB.Department of Laboratory Medicine, School of Medicine, University of California, San Francisco > > “How did it happen that cholesterol-lowering agents were approved by the FDA for long-term use in spite of their animal carcinogenicity?†> > Thomas B. Newman, MD, MPH, Stephan B. Hulley, MD, MPH in their research on Carcinogenicity of Lipid-Lowering Drugs went to dig in the minutes of the Endocrinologic and Metabolic Drugs Advisory Committee meetings (under the Freedom of Information Act) during the discussion for the approbation of the drug gemfibrozil (October 17, 1988) > > What they found is beyond imagination and left me speechless. “Dr. Gloria Troendle (deputy director, Division of Metabolism and Endocrine Drug Products for the FDA) noted that gemfibrozil belongs to a class of drugs that has been shown to increase total mortality. It has been shown to have animal carcinogenicity and she does not believe the FDA has ever approved a drug for long-term prophylactic use that was carcinogenic at such low multiples of the human dose as gemfibrozil?â€To make a long story short, only three of the nine members of the advisory committee believed that the benefit of gemfibrozil outweighs the risk. The FDA ignored the committee’s recommendation and granted approval to the drug gemfibrozil. Under the Health Sentinel you will find a section on the FDA that will give you a better idea of what they’re all bout. > You can find all the information at: http://www.captainclark.com/Pages/jamareport.html > ======================================================= > What They Should Tell You Urgently about statins and coenzymeQ10 > > CQ10 is an antioxidant which protects he energy-producing parts of a cell (mitochondria) from toxic substances.Statins deplete coenzyme Q10 from your muscles and from your blood.Even worse, it blocks the biosynthesis of coenzyme CoQ10. > You can actually lose up to 50% of your CoQ10. Your heart is the muscle that consumes and needs Q10 the most in order to function. > Coenzyme Q (10) and statins: Biochemical and clinical implications. Littarru GP, Langsjoen P. Institute of Biochemistry, Polytechnic University of the Marche, Via Ranieri, 60131 Ancona, Italy > > > In patients with pre-existing congestive heart failure, the addition of statin therapy causes a decrease in blood CoQ10 levels and a decline in myocardial function. > Folkers K., Langsjoen P., Willis R., Richardson P., Xia L., et al. Lovastatin decreases coenzyme Q levels in humans. Proc. Nat Acad. Sci. USA. 87: 8931-8934, 1990 > > CoQ10 is essential for the health of your heart. This is an antioxidant used by Alternative Medicine practitioners to fight CHD on a daily basis. In a healthy heart there is more CoQ10 than in any other muscle of the body. > Folkers K, Littarru GP, Ho L, Runge TM, Havanonda S, Cooley D. Evidence for a deficiency of coenzyme Q10 in human heart disease. Int Z vitaminforsch 1970; 4(3):380-390. > > > A Silent Killer? > > tip_icon The researchers at Ghirlanda reported in a double-bind, placebo-controlled study a decrease of 50-54% of CoQ10 levels in the statin treatment groups, (1) and similar results were reproduced by Watts. (2) > (1) Ghirlanda G, Oradei A, Manto A, Lippa S, Uccioli L, Caputo S, Greco AV, Littarru GP. > Evidence of plasma CoQ10-lowering effect by HMG-CoA reductase inhibitors: a double-blind, > placebo-controlled study. J Clin Pharmacol. 1993.Mar;33(3):226-229 > (2) Watts GF, Castelluccio C, Rice-Evans C, Taub NA, Baum H, Quinn PJ. Plasma coenzyme Q (ubiquinone) > concentrations in patients treated with simvastatin. J Clin Pathol. Nov 1993;46(11):1055-1057. > Could It Be Dangerous? > > > Canada insisted on warning labels for the need for supplemental CoQ10 to be placed on every statin prescription. > > Before taking a statin, patients should tell their doctor or pharmacist if they: > > • Are pregnant, intend to become pregnant, are breast-feeding or intend to breast-feed. > • Have thyroid problems. > • Regularly drink three or more alcoholic drinks daily. > • Are taking other cholesterol lowering medication such as fibrates (gemfibrozil, fenofibrate) or niacin. > • Are taking other medications, including prescription, non-prescription and natural health products, as drug interactions are possible. > • Have a family history of muscular disorders. > • Had any past problems with their muscles (pain, tenderness), after using a statin. > • Have kidney or liver problems. > • Have diabetes. > • Have undergone surgery or other tissue injury. > • Do excessive physical exercise. > Health Canada advises consumers about important safety information on statins > ============================================= > Sorry for the length of this article this only part of the iceberg see: http://www.jmbblog.com/coronary-heart-disease-best-kept-secrets-part-3-drugs/ > > 95 % of CHD can be reversed with a couple of supplements and nutrition . I forgot.. from a recent research : statins increase the risk of heart attacks. > John > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 6, 2009 Report Share Posted April 6, 2009 I forgot : statins inhibit not only the liver from making cholesterol but may also block the brain from making cholesterol. That's a serious consequence, according to Yeon-Kyun Shin, a biophysics professor in the department of biochemistry, biophysics and molecular biology at Iowa State, because cholesterol is vital for healthy and optimum brain function. Research presented last month at the yearly American Heart Association meeting was the first to report on the alarming trend that heart failure has more than doubled in the past twenty-six years, getting worse each year. The worsening rates directly parallel the increased use of statins, although the researcher did not bother looking at this obvious likely cause. ================================================================ natural Statins: GUGGUL RED YEAST RICE others good products that will help garlic, ground flaxseed, barley and artichoke extract may be helpful in keeping cholesterol levels in healthy balance. ============================================================== GUGGUL AND RED RICE YEAST WORK LIKE STATINS. YOU STILL NEED TO TAKE COQ 10 !! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 8, 2009 Report Share Posted April 8, 2009 , shaman urban <shaman_urban wrote: > > Research presented last month at the yearly American Heart > Association meeting was the first to report on the alarming trend > that heart failure has more than doubled in the past twenty-six > years, getting worse each year. The worsening rates directly > parallel the increased use of statins, although the researcher > did not bother looking at this obvious likely cause. Speaking of not bothering to look at likely obvious causes, modern diets contain 300% more polyunsaturated fat than they did 100 years ago, yet you insist that saturated fats are to blame for the heart disease epidemic. Riiiiiiight... traditional foods are the cause of modern diseases... and the world is flat !! > ================================================================ > natural Statins: > GUGGUL > RED YEAST RICE > others good products that will help > garlic, ground flaxseed, barley and artichoke extract may be helpful in keeping cholesterol levels in healthy balance. > ============================================================== > GUGGUL AND RED RICE YEAST WORK LIKE STATINS. YOU STILL NEED TO > TAKE COQ 10 !! The simplest of Google searches will reveal that guggul works completely differently than statins. And, red rice yeast will only work like a statin if it actually contains a substance that is chemically identical to Lovastatin. However, the FDA forbids the sale of red rice yeast products that contain the naturally occurring statin. The thing is, statins do almost nothing to prolong life. Double blind, placebo controlled studies of statin drugs show no decreased all-cause mortality for all women and most men. There was slightly decreased all-cause mortality for men under the age of 65 who had already had a heart attack. Bottom line, though, is that worrying about total cholesterol numbers is a waste of time. People focus on the correlation between high cholesterol and heart disease while ignoring the correlation between low cholesterol and increased mortality and most other diseases. And, with 50% of heart attacks occurring in people with supposedly normal cholesterol numbers, total cholesterol really isn't a very good gauge of cardiac health. With respect blood lipids, the numbers you need to keep an eye on are the various ratios, specifically: total cholesterol/HDL (should be less than 4) LDL/HDL (should be less than 3) Triglycerides/HDL (should be less than 1.8) Quote Link to comment Share on other sites More sharing options...
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