Chemical Causes of Diabetes: Overeating Is Not the Only Problem

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Chemical Causes of Diabetes: Overeating Is Not the Only Problem

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by Mark Sircus Ac., OMD

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(NaturalNews) Medical science has discovered how sensitive the insulin

receptor sites are to chemical poisoning. Metals such as cadmium, mercury,

arsenic, lead, fluoride and possibly aluminum may play a role in the actual

destruction of beta cells through stimulating an auto-immune reaction to them

after

they have bonded to these cells in the pancreas. It is because mercury and

lead attach themselves at highly vulnerable junctures of proteins that they

find

their great capacity to provoke morphological changes in the body. Changes

in pancreatic function are among the pathogenetic mechanisms observable during

lead intoxication.

 

The following is an excerpt from the Book " Survival Medicine for the 21st

Century " by Dr. Mark Sircus.

 

**The development of insulin-dependent diabetes mellitus is thought to be

dependent on the interaction of environmental agents with the pancreatic beta

cells.** - University of Calgary

 

Lead exposure has been associated with an increased risk of hypertension,

and is a well-established risk factor for kidney disease. Whether lead affects

blood pressure indirectly through alterations in kidney function or via more

direct effects on the vasculature or neurologic blood pressure control is

unknown though. Researchers at Harvard Medical School state, **Our findings

support the hypothesis that long-term low-level lead accumulation (estimated by

tibia bone lead) is associated with an increased risk of declining renal

function particularly among diabetics or hypertensives, populations already at

risk for impaired renal function.**

 

Cadmium is a widespread environmental pollutant that accumulates in the

pancreas and exerts diabetogenic effects in animals. In a large cross-sectional

study, urinary cadmium levels are significantly and dose-dependently

associated with both impaired fasting glucose and diabetes. Transsulfuration

pathways

in the body are fundamental for life. When mercury blocks thiol groups

cellular proteins lose their reactive properties, lose their ability to carry

out

their routine function. Insulin has three sulfur-containing cross-linkages and

the insulin receptor has a tyrosine kinase-containing sulfur bond, which are

the preferred targets for binding by both mercury and lead. Should mercury

attach to one of these three sulfur bonds it will interfere with the normal

biological function of the insulin molecule. Mercury, many times more toxic

than lead, is so dangerous exactly because it is collapsing/damaging critical

sulfur-containing cross-linkages which change the geometry of both insulin

receptor sites and insulin itself.

 

**Commercials tell children that junk food is good food -- the latest

message from an industry that spends $10 billion a year marketing to

children.** -

New York Times

 

Food is not considered junk just because of high fat or sugar content, there

is a long list of poisonous chemicals used by the food industry that are

striking people down. And there are many serious nutritional deficiencies in

today’s food that diminish the body's capacity to deal safely with these

chemicals and heavy metals -- with magnesium and selenium deficiencies at the

top of

the list. For instance, according to Dr. Ellen Silbergeld, a researcher from

the Johns Hopkins School of Public Health, the poultry industry’s practice

of using arsenic compounds in its feed is something that has not been studied:

**It’s an issue everybody is trying to pretend doesn’t exist.** Arsenic

exposure is a risk factor for diabetes mellitus. Inorganic arsenic is

considered

one of the prominent environmental causes of cancer mortality in the world.

Chicken consumption may contribute significant amounts of arsenic to total

arsenic exposure of the U.S. population according to the Journal Environmental

Health Perspectives.

 

**Arsenic acts as a growth stimulant in chickens -- develops the meat faster

-- and since then, the poultry industry has gone wild using this

ingredient,** says Donald Herman, a Mississippi agricultural consultant and

former

Environmental Protection Agency researcher who has studied this use of arsenic

for

a decade. At mean levels of chicken consumption (60 g/person/day), people

may ingest 1.38-5.24 micrograms/day of inorganic arsenic from chicken alone. At

the 99th percentile of chicken consumption (350 g chicken/day), people may

ingest 21.13-30.59 micrograms inorganic arsenic/day and 32.50-47.07 micrograms

total arsenic/day from chicken. This can lead to prostate cancers. It can

also cause neurological, cardiovascular, gastrointestinal, and immune system

abnormalities. The feeding of arsenic to chickens in the United States releases

hundreds of tons of arsenic into the environment every year in the form of

poultry manure, which is spread on fields as fertilizer.

 

Researchers from the Department of Internal Medicine, National Taiwan

University Hospital found, **The association between arsenic exposure and

diabetes

mellitus is a relatively new finding. Up to now, there are six epidemiologic

reports linking diabetes mellitus with arsenic exposure from environmental

and occupational sources. Two reports in Taiwan carried out in the blackfoot

disease -- hyperendemic villages, one cross-sectional and one prospective

follow-up of the same cohort -- indicate that arsenic exposure from drinking

artesian well water is associated with prevalence and incidence of diabetes

mellitus in a dose-responsive pattern.

 

The observation of the relation between arsenic exposure and diabetes

mellitus is further supported by studies carried out in Sweden and Bangladesh.

In

Sweden, case-control analyses of death records of copper smelters and glass

workers revealed a trend of increasing diabetes mellitus with increasing

arsenic exposure from inhalation. In Bangladesh, prevalence of diabetes

mellitus

among arsenic-exposed subjects with keratosis was about five times higher than

unexposed subjects.**

 

Wistar rats were made diabetic with a single injection of Alloxan

 

Another example is Alloxan. Studies show that Alloxan, the chemical that

makes white flour look **clean and beautiful** destroys the beta cells of the

pancreas. Scientists have known of the alloxan-diabetes connection for years

yet there seems to be a conspiracy that defends the integrity of the FDA, which

allows dangerous chemicals that can cause diabetes to be used in drugs and

food. " A growing body of research shows that pesticides and other contaminants

are more prevalent in the foods we eat, in our bodies, and in the

environment than we thought,†all confirming the chemical nightmare in

progress.

 

According to research conducted by Dr. H.J. Roberts, a diabetes specialist,

a member of the ADA, and an authority on artificial sweeteners, aspartame:

 

1) Leads to the precipitation of clinical diabetes.

 

2) Causes poorer diabetic control in diabetics on insulin or oral drugs.

 

3) Leads to the aggravation of diabetic complications such as retinopathy,

cataracts, neuropathy and gastroparesis.

 

4) Causes convulsions.

 

Dr. Roberts said, **The loss of diabetic control, the intensification of

hypoglycemia, the occurrence of presumed 'insulin reactions' (including

convulsions) that proved to be aspartame reactions, and the precipitation,

aggravation or simulation of diabetic complications (especially impaired vision

and

neuropathy) while using these products.** The FDA's own toxicologist, Dr.

Adrian

Gross told Congress that without a shadow of a doubt, aspartame can cause

brain tumors and brain cancer and violated the Delaney Amendment which forbids

putting anything in food that is known to cause Cancer. It is a monstrous

crime to poison the food and water supplies yet this is exactly what the FDA

has

been approving and undoubtedly they are, in large part, responsible for

flaming the diabetic winds. As the use of MSG and aspartame grows, the

incidence

of obesity appears to be growing.

 

MSG causes a very large insulin response after it is ingested since there

are glutamate receptors in the pancreas. MSG opens calcium channels, thus

constricting blood vessels –- this may put diabetics with high blood pressure

at

risk by negating calcium channel blocker medication. In 1968, John W. Olney,

M.D., a respected researcher at Washington University Medical School, St.

Louis, Missouri, and member of the National Academy of Science, found that mice

in his laboratory that were being used to replicate a 1957 study by Lucas and

Newhouse, in which the administration of MSG had resulted in retinal damage,

had become grotesquely obese. Since 1969, many scientists have confirmed Dr.

Olney's findings of damage to the hypothalamus from MSG with resulting

obesity. Even the rats used in obesity, diabetes and exercise studies are made

obese

by injecting MSG. MSG may cause food addiction and though efforts have been

made to reduce its use in processed and restaurant foods, it remains hidden

by semantics, now called such things as “hydrolyzed proteinâ€. Scientists in

Spain have recently concluded that MSG when given to mice increases appetite

by as much as 40%.

 

There is abundant literature demonstrating that MSG and aspartic acid cause

hypothalamic lesions which, in turn, can cause gross obesity. Although there

are a number of causes for obesity, there is no question that one of the main

causes for the obesity epidemic is the ever increasing use of MSG and

aspartame.

 

We know that the hypothalamus is very immature at birth. The damage to this

structure of the brain by MSG leads to severe endocrine problems later in

life, among them decreased thyroid hormone, increased tendency toward diabetes,

and higher cortisone levels than normal. A child consuming a soup containing

MSG plus a drink with NutraSweet will have a blood level of excitotoxins six

times the blood level that destroys hypothalamus neurons in baby mice.

 

And we are just beginning to hear that a massive mistake has been made with

genetically modified foods, which can only fan those diabetic winds. Dr.

Arpad Pusztai, for instance, has already shown that genetically-manipulated

foods

can, when fed to animals in reasonable amounts, cause very gradual organ and

immune system damage. Another study, carried out by Dr. Irina Ermakova at

the Institute of Higher Nervous Activity and Neurophysiology, at the Russian

Academy of Sciences, found that more than half of the offspring of rats fed on

modified soya died in the first three weeks of life, six times as many as

those born to mothers with normal diets. Dr. Manuela Malatesta and colleagues

in

the Universities of Pavia and Urbino in Italy, showed that mice fed on GM

soya experienced a slowdown in cellular metabolism and modifications to the

liver and pancreas. Researchers are reviving fears that GM food damages human

health and certainly would not be indicated for children or for people with

diabetes.

 

Many bottled soft drinks and related beverages contain benzene, a well-known

carcinogen. The EPA defines a **safe** level of benzene as zero. Yet the

Environmental Working Group, a watchdog organization, found levels of benzene

in

soft drinks at levels between 5 and 138 parts per billion. A fair amount of

benzene is taken in by our bodies by air pollution and drinking water. The

U.S. Food and Drug Administration has known for almost 15 years that potassium

benzoate and sodium benzoate react with ascorbic acid to form benzenes. Potass

ium benzoate, sodium benzoate and ascorbic acids are all commonly used to

preserve freshness in soft drinks.

 

The excess of diabetes reported for the Benzene Sub registry occurred in the

group aged 10 to 17 years, suggesting it is likely that IDDM is the type of

diabetes most prevalent. It has been demonstrated that most IDDM patients

have autoantibodies to the pancreas (Lernmark et al., 1981), as well as to

other

organs Benzene has been shown to stimulate the

hypothalamic-pituitary-adrenocortical (HPA) axis of mice (Hsieh et al., 1991),

accompanied by increased

ACTH/corticosterone release into the blood.

 

Corticosteroids are associated with the development of diabetes by reducing

insulin sensitivity, or possibly by impairing islet function frequently

associated with the development of impaired glucose tolerance. The secretion of

anti-insulin hormones, such as growth hormones or adrenocorticotrophic hormone

(ACTH), are also believed to play an important role in IDDM development

(Rodriguez, 1986). Steroid hormones play an important role in determining the

severity of beta cell damage in the infected mouse, with androgens and

glucocorticoids being particularly critical (Craighead, 1981). Ethanol can

enhance the

immunosuppressive effects of benzene. In addition, it has been demonstrated

that various benzene metabolites depress the production of interferon (Cheung

et al., 1988; Popp et al., 1992). IDDM is associated with a variety of

hematologic changes (such as anemia) and malignancies (such as lymphocytic

leukemia, lymphoma, and multiple myeloma) that might be directly related to or

simply

coincidental with the diabetes (Bern, 1982). From the literature reported it

can be seen that all of these conditions are also associated with exposure

to benzene.

 

Anthropogenic emissions to the air are approximately 34,000 metric tons per

year (USEPA, 1989), Absorption of benzene varies with route of exposure. In

humans, respiratory uptake has been determined to vary from approximately 47%

(Nomiyama and Nomiyama, 1974) to 80% (Srbova et al., 1950), although dermal

absorption can range from 0.05% to 0.2% (Franz, 1984). Absorption data for

oral exposure in humans is not available; however, in animals, absorption rates

following oral exposure to benzene were found to be from 90% to almost 100%

(Parke and Williams, Ingestion of contaminated food items has been suggested

as a potentially important pathway of human exposure to benzene (Hattemer-Frey

et al., 1990 and many foods contain high levels of benzene. Benzene is

ubiquitous in the environment, having been measured in air, water, and human

biological samples. The major environmental sources include automobile exhaust,

automobile refueling, hazardous waste sites, underground storage tanks that

leak, waste water from industries that use benzene, chemical spills, chemical

manufacturing sites, and petrochemical and petroleum industries (Fishbein,

1992; Edgerton and Shah, 1992).

 

Recently drinking more than one soft drink daily -- whether it's regular or

diet -- may be associated with an increase in the risk factors for heart

disease and diabetes, Framingham researchers reported in Circulation: Journal

of

the American Heart Association. **In those who drink one or more soft drinks

daily, there was an association of an increased risk of developing the

metabolic syndrome.** Metabolic syndrome is a cluster of cardiovascular disease

and

diabetes risk factors including excess waist circumference, high blood

pressure, elevated triglycerides, low levels of high-density lipoprotein (HDL

" good " cholesterol) and high fasting glucose levels.

 

Prior studies linked soft drink consumption to multiple risk factors for

heart disease. However, this study showed that the association not only

included

drinking regular calorie-laden soft drinks, but artificially sweetened diet

sodas as well, researchers said. " If you are drinking one or more soft drinks

a day, you may be increasing your risk of developing metabolic risk factors

for heart disease. "

 

The researchers also observed that compared to participants who drank less

than one soft drink daily, those who drank one or more soft drinks a day had

a:

 

* 31 percent greater risk of developing new-onset obesity (defined as a body

mass index [bMI] of 30 kilograms/meter2 or more);

 

* 30 percent increased risk of developing increased waist circumference;

 

* 25 percent increased risk of developing high blood triglycerides or high

fasting blood glucose;

 

* 32 percent higher risk of having low HDL levels. " It didn't matter whether

it was a diet or regular soft drink " .

 

**Results also don't appear to be driven by the dietary pattern of soft

drink users, i.e, by other food items that are typically consumed along with

soft

drinks,** Vasan, the study author, said. So perhaps what we have blamed for

so long, the high fructose corn syrups, the empty calories, the aspartame in

soft drinks, is not the only thing causing an increase in these diabetic risk

factors. In combination with benzenes, it is highly likely that we have

found yet another toxic substance that adds to our inability to avoid diabetes.

 

**Diabetes may in fact be a major side effect of antibiotics and other

common pharmaceuticals.** - Dr. Lisa Landymore-Lim, Independent scientist for

Atomic Health Limited

 

Doctors are on notice that many drugs have toxic effects that can

participate in destroying insulin creation and cell receptivity to it. In her

1994

book, Poisonous Prescriptions, Landymore-Lim says that diabetes may in fact be

a

major side effect of pharmaceutical drugs. The book provides evidence from

studies and hospital records. Diabetes, usually thought to be largely a genetic

disorder, may actually have increased so much in the last 50 years due in

large part to the proliferation in the use, and over-use, of medicines. In 2004

the American Diabetes Association, the American Psychiatric Association, the

North American Association for the Study of Obesity, and the American

Association of Clinical Endocrinologists made a similar announcement warning

people

to be careful to watch for signs they are developing diabetes, obesity or

high cholesterol if they are taking Abilify, Clozaril, Geodon, Risperdal,

Seroquel or Zyprexa. What medicines, food and water have increasingly in common

are the chemical poisons they contain.

 

Researchers at the University of Liverpool recently released their studies

that examined the toxic effects on nerve cells in the laboratory of using a

combination of four common food additives -- aspartame, monosodium glutamate

(MSG) and the artificial colourings brilliant blue and quinoline yellow. The

findings of their two-year study were published at the end of 2005 in the

journal Toxicological Sciences. The Liverpool team reported that when mouse

nerve

cells were exposed to MSG and brilliant blue or aspartame and quinoline

yellow in laboratory conditions, combined in concentrations that theoretically

reflect the compound that enters the bloodstream after a typical children's

snack and drink, the additives stopped the growing of nerve cells and

interfered

with proper signaling systems. The mixtures of the additives had a much more

potent effect on nerve cells than each additive on its own.

 

The study reported that the effect on cells could be up to four times

greater when brilliant blue and MSG were combined and up to seven times greater

when quinoline yellow and aspartame were combined, than when the additives were

applied on their own. What we can begin to conclude is that future research

is going to show how all the toxic chemicals in the food, air, water and

medicines we consume are combining to destroy our health. Any one poison

discussed

here in sufficient quantity can destroy cell physiology, the pancreas beta

cells, and diminish cell receptivity to insulin.

 

We are depending more and more on processed foods, and with each year, the

FDA approves more and more chemicals for use in foods. With each year, the

food industry is using more and more chemicals in their products. These

chemicals increase shelf life, kill bacteria, improve taste, replace fats,

replace

carbohydrates, and cause chronic diseases that eventually kill people. Junk

food is really a cover up image for something quite a bit nastier than the

image

that junk congers. Junk foods are actually slow-acting poisons because they

come to us loaded with highly toxic chemicals. We can only imagine the worst

when we think about FDA approval processes for in reality the FDA is

poisoning the public. The FDA is the wellhead of most iatrogenic diseases and

death.

There is no excuse for an agency charged with protecting public health to

have allowed the massive poisoning of the public via food, drugs and public

water supplies.

 

Bisphenol A Exposure May Lead to Obesity

 

Bisphenol A (BPA) exposure may lead to obesity, altered glucose metabolism,

insulin resistance and Diabetes. Not only are chemicals used in foods,

affecting the rates of diabetes, but chemicals used in everyday plastics are

contributing to the rise in obesity and insulin resistance.

 

Debate over BPA is one of the most contentious environmental health issues

faced by government and industry. Traces are found in the bodies of nearly all

Americans tested, and low levels -- similar to amounts that can leach from

infant and water bottles –- mimic estrogen.

 

Extensive scientific literature reports adverse health effects from

bisphenol A at very low doses. Studies show that bisphenol A can alter the

expression

of several hundred genes with effects varying among special tissues and

depending upon the timing of exposure. More than 150 laboratory animal studies

suggest that bisphenol A exposure at very low doses is linked to a staggering

number of health problems, including prostate and breast cancer, obesity,

hyperactivity, diabetes, altered immune system, lowered sperm count, and early

puberty.

 

A study by Dr. Beverly Rubin and her colleagues at Tufts University Medical

School showed that bisphenol A makes rodents grow larger after they are

exposed in the womb, confirming similar findings from previous studies (17).

When

rats were fed 100 µg/kg/day of bisphenol A during pregnancy through

lactation, their offspring were notably heavier after birth and into adulthood.

Significantly, in the female offspring, the lower of the two bisphenol A doses

used

in the study produced a larger and more persistent effect on body weight

relative to the higher dose. In addition, the fact that the effect persisted

long after exposure for the female offspring suggests that bisphenol A may

increase the number of fat cells in the rats and predispose them to heavier

weight

throughout life.

 

In 2002, a team of researchers at the Ehime College of Health Science in

Japan discovered that bisphenol A can increase the conversion of embryonic

cells

into fat cells (18). In the body, this effect could result in larger numbers

of fat cells developing. In addition to converting to fat cells, treated

cells increased their fat content by 150 percent over 11 days. Combined with

insulin, bisphenol A increased the fat content of cells by 1300 percent. In

other words, this experiment documented that bisphenol A could trigger and

promote the two main processes in developing obesity. In 2004, another study

confirmed these findings, showing that bisphenol A alone and with insulin

increased

the uptake of sugar into fat cells (19).

 

A recent study by Dr. Paloma Alonso-Magdalena and her colleagues showed that

low-level, chronic exposure of adult mice to 10 µg/kg/day of bisphenol A

caused insulin resistance, the precursor to Type II diabetes in people as well

as hypertension and cardiovascular disease (20). Dr. Alonso-Magdalena’s study

showed that even a single dose of bisphenol A at levels currently found in

humans can result in altered levels of blood glucose and insulin, and twice

daily exposure for just four days results in insulin resistance.

 

Several studies show an increased rate of postnatal growth in both males and

females as a result of maternal doses between 2.4 and 500 µg/kg/day (21).

Accelerated postnatal growth is associated not just with obesity but with

insulin resistant diabetes, hypertension, and heart disease as well.

 

Is it any wonder that we are seeing the rising rate of diabetes in our

children and adolescents? The use of bisphenol A and the products containing

them

have increased through the years as our use of glass and safer non plastic

containers has decreased. Its hard to even find non-plastic onctainers for

everyday use. And what is especially disturbing is news coming to light that

bisphenol A is being used in baby bottles for the feeding of our infants at a

very early age.

 

The number of children in the U.S. that are overweight have doubled in the

last 30 years (National Institutes of Health). Currently about 20% of

children, or one child in five is overweight. The increase is true for children

and

adolescents of all age groups and races and for boys and girls.

 

Rising Obesity Trend in Adolescents

 

Bisphenol A is a polycarbonate plastic. Bisphenol A-based polycarbonate is

used as a plastic coating for children's teeth to prevent cavities, as a

coating in metal cans to prevent the metal from contact with food contents, as

the

plastic in food containers, refrigerator shelving, baby bottles, water

bottles, sport drink bottles, returnable containers for juice, milk and water,

micro-wave ovenware and eating utensils. In a small prospective study,

researchers in Japan report that bisphenol A levels are higher in women with a

history

of repeated spontaneous miscarriages. This research was based on proof that

BPA causes meiotic aneuploidy in mice. Meiotic aneuploidy is the commonest

cause of miscarriage in people.

 

The effects of this chemical on our chromosomes will reach into generations

yet to come affecting not only ourselves, but our children and our

grandchildren. Researchers have found that the effects of continual low dose

exposures

may not show up for years. Growing children are particularly at risk to toxic

chemicals in their environment because they are physiologically more

susceptible to them.

 

The Lancet analysed the prevalence of Type 2 diabetes in Ontario, Canada

between 1995 and 2005. It found an increase of 69 per cent over the 10 years

compared with the World Health Organisation's prediction of a 39 per cent

increase between 2000 and 2030. Dr. Lorraine Lipscombe, of the Institute for

Clinical Evaluation Science, Toronto, said that it also saw a higher rise in

the

rate of cases in younger people under 50 than in older people. " A 27 per cent

increase has taken place after only five years, " she said. " Rising rates of

obesity could be the cause of this striking growth and effective public health

interventions to manage and prevent obesity are sorely needed. "

 

The CDC says that diabetes is disabling, deadly and on the rise. The

incidence of diabetes is skyrocketing not only in adults but in the juvenile

population as well. Healthcare experts have called the alarming rise in

diabetes and

its related complications “an epidemic†that threatens to spiral out of

control.

 

In 1997, 15.7 millions adults in the United States were reported to have

diabetes. By the year 2002, this number had already swelled to 18.0 million or

8.7% of all adults. Diabetes and its complications now claim hundreds of

thousands of lives in the U.S. each year, incurring total expenses of over $130

billion in direct and indirect costs to the healthcare system. Worldwide, the

number of people with adult-onset diabetes is predicted to explode in the next

10 years, doubling to an estimated 221 million people. By contrast only

43,171 people in the United States were diagnosed with AIDS and only 18,017

died.

 

Scientists have discovered a variant gene that leads to a sizable extra risk

of Type 2 diabetes -- 38 percent of Americans who have inherited a single

copy of the gene have a 45 percent greater risk of Type 2, the estimated 7

percent who carry two copies are 141 percent more likely to develop the

disease.

What scientists are saying is that if all the variant genes in the population

were erased, so would be 21 percent of diabetes cases. Another way of

expressing variations in genetic makeup is constitution. Some people are gifted

with stronger constitutions (genes) than others and are more able to stand up

to

massive chemical assaults on their bodies. Genetic causes do not in anyway

explain the explosive increases in diabetes but increasing concentrations of

environmental poisons penetrating our bodies via our air, water, food and

medicines can evoke breakdowns in genetic function.

 

Women who reported mixing and applying agricultural pesticides during early

pregnancy have a two times higher risk of developing gestational diabetes

during the pregnancy. The strong association between first trimester pesticide

exposure and gestational diabetes mellitus suggests that pesticide exposures

may affect glucose metabolism and insulin resistance. Specifically, four

herbicides (2,4,5-T; 2,4,5-TP; atrazine; or butylate) and three insecticides

(diazinon, phorate, or carbofuran) were associated with reporting gestational

diabetes. Women who reported agricultural pesticide exposure (mixing or

applying

pesticides to crops or repairing pesticide application equipment) during

pregnancy were more than twice as likely to report GDM as compared to women

reporting no pesticide use in pregnancy.

 

Exposure to dioxins by any route is known to cause various systemic effects

in exposed animals. The general population is exposed to small amounts of

dioxins, as exemplified by the fact that dioxins have been found in virtually

all samples of adipose tissue and blood (serum lipids) from individuals with no

known previous exposure. It is primarily the dioxins with chlorine atoms in

the 2, 3, 7 and 8 positions that are retained in animals and humans and which

selectively concentrate in body fat and lipids. A recent study on the health

status of Vietnam veterans who participated in Operation Ranch Hand did not

find any signs of liver disease, but did report increased levels of

triglycerides and cholesterol in the blood (a second report does not support

these

increases). In addition, an increase in body fat, diabetes, and blood pressure

were also noted. These effects were strongly associated with TCDD levels in

the serum.

 

Ranch Hand veterans also had changes in blood (increased white blood cells,

platelet, IgA, and sedimentation rates) which suggest a chronic inflammatory

response. It has take two decades of litigation for the U.S. Government to

finally recognize the devastating effects of dioxin exposure that have disabled

our veterans with cancers and diabetes. The average time it takes to remove

one half of the TCDD from the body is around 7 years. The half-lives of other

dioxins in the body are not known. About 98% of the daily intake of dioxins

for the general population comes from ingesting food and milk. Inhalation

exposure to dioxins for the general population constitutes a minor portion of

daily intake. Average intake of TCDD for adults has been calculated to be about

25 picograms (pg) per day or 0.35 pg per kilogram (kg) of body weight per

day. If all dioxins and furans are included and TEFs are used, the total

average daily intake of TCDD equivalents for adults is about 90 pg/day or 1.3

pg/kg

body wt/day.

 

There are numerous other sources that contribute to dioxins in the

environment. Dioxins are known to form concurrently with furans during

combustion

processes such as: incineration of municipal solid waste and industrial waste,

and are associated with ash generated in the incineration process. Emissions

from these sources vary greatly and depend on management practices and the

applied technologies. Combustion of many chlorine-containing materials (such as

plastic material like polyvinyl chloride, paper, wood treated with

pentachlorophenols, pesticide-treated waste, and PCBs) can produce dioxins and

furans.

Dioxins and furans have also been detected in emissions from coal-fired power

plants, home-heating systems, exhaust from cars running on leaded gasoline,

and cigarette smoke.

 

Phthalates are a group of man-made chemicals that are structurally related

to the organic acid, phthalic acid. The most important use of phthalates is in

plastics, especially PVC where they act as plasticisers. Phthalates are also

present in a wide range of industrial, household and consumer products,

including personal care products. such as nail polish, hair sprays, soaps,

shampoos, perfumes, moisturizers. They are found in pipes, vinyl wall and floor

coverings, roofing materials, safety glass, car parts, lubricating oils,

detergents, food packaging, adhesives, paints, inks, medical tubing, blood

bags,

pharmaceuticals, footwear, electrical cables, stationery, and (until recently)

in toys.

 

More than 75% of the U.S. population carries detectable levels of several

phthalate metabolites. Studies have found associations between some phthalate

metabolites and antiandrogenic effects in humans, including both infant and

adult males. Recently a study published in Environmental Health Perspectives

showed that exposure to phthalates correlated with two metabolic abnormalities

in men: abdominal obesity and insulin resistance. Four phthalate metabolites

were significantly associated with greater waist circumference and three with

increased insulin resistance, PCP (organic chemical Pentachlorophenol) was

used in the timber industry for years as a cheap treatment for sapstain, a

fungal infection commonly found in softwoods such as pine. It is an organic

chemical produced by reacting chlorine gas with phenol. The process creates a

number of toxic impurities such as tetrachlorophenol, hexachlorobenzene and

several types of dioxins and dibenzofurans. The main route of absorption is

through the skin. Some of the more chronic health effects, including cancer and

diabetes, do not appear until long after exposure. The sawmill workers were

constantly exposed to PCP as they mixed chemicals and handled wet, treated

timber.

 

According to the World Health Organization DIAMOND Project Group on

Epidemics, a major difficulty in the area of IDDM research -- despite strong

epidemiologic evidence that environmental agents are potent causes of IDDM

(Diabetes

Epidemiology Research International, 1987) -- is that the identification of

such agents has been elusive. It is noteworthy that several recent

epidemiologic studies have reported that the incidence of IDDM is increasing,

suggesting

that long-term changes in the environment are altering the probability of

eventual diabetes.

 

Among the most pernicious substances ever created is a group of chemicals

known as POPs or Persistent Organic Pollutants. Among them: DDT, dioxins, PCBs

and Chlordane. And even though twelve POPs -- the so-called " dirty dozen " --

were restricted or banned by international convention in 2003, they continue

to pose a threat to people and wildlife because POPs accumulate in the food

we eat. Virtually every person on the planet has POPs in their body and the

chemicals have been linked to cancers, birth defects and disabilities. Now a

group of researchers in Korea have found strong evidence linking POPs and

diabetes.

 

Dr. David Carpenter, Professor of Environmental Health and Toxicology at the

State University of New York at Albany, reviewed the Korean study and said, “

Well, one considers individual pollutants the magnitude was between three

and five fold increased risk but the most striking observation was when they

considered the sum of all six pollutants that they monitored and they selected

pollutants that we all have in our bodies so that very few individuals had

levels below the level of detection. Under those circumstances they were

getting increased risk of the order of thirty-eight fold which is absolutely

enormous.â€

 

" The amount of persistent organic pollutants in each person's body is a

reflection of their diet, where they live, what the concentration of these

substances is in the air they breathe, and probably related to how rapidly they

metabolize these compounds. " - Dr. David Carpenter

 

Dr. Carpenter continued saying, “The most interesting observation in this

paper is that there was no relationship between being obese and developing

diabetes in those persons that did not have high levels of these organic

pollutants in their bodies. It may well be that people that are obese eat much

more

animal fat than people that are not obese and these persistent organic

pollutants are all found in animal fats. So the question really is whether it

is the

obesity that leads to the diabetes or rather the presence of these

persistent organic pollutants. It may well be that it's the pollutants that

cause the

diabetes, not the obesity.â€

 

" In the human body these compounds last about ten years before you get rid

of half of them. In the environment they're even more persistent. " - Dr. David

Carpenter

 

Food is not considered junk just because of high fat or sugar content, there

is a long list of poisonous chemicals used by the food industry that are

striking people down. And there are many serious nutritional deficiencies in

today’s food that diminish the bodies capacity to deal safely with these

chemicals and heavy metals -- with magnesium and selenium deficiencies at the

top of

the list.

 

Magnesium deficiency is a predictor of diabetes; diabetics both need more

magnesium and lose more magnesium than most people. In two new studies, in both

men and women, those who consumed the most magnesium in their diet were

least likely to develop type 2 diabetes, according to a report in the January

2006 issue of the journal Diabetes Care.

 

The human race is facing an abyss, a massive breakdown in body chemistry.

All indications suggest that the medical industrial complex will not squarely

face the facts and the research and will not work in earnest to reduce the

chemical exposures the masses are facing. Too much money is involved in

manufacturing hundreds of millions of tons of chemicals each year and huge

fortunes

are made by the economic elite in the sale of toxins that are dragging large

segments of the population to their sick beds and early graves. Our

civilization is poisoning itself and the medical and dental communities

participate

with passion.

 

References:

 

Yoon, JW et al. Effects of environmental factors on the development of

insulin-dependent diabetes mellitus. Department of Microbiology and Infectious

Diseases, Julia McFarlane Diabetes Research Unit, University of Calgary,

Alberta, Canada. Clin Invest Med. 1987 Sep;10(5):457-69

 

Toxicity of Fluoride to Diabetic Rats. C.A.Y. Banu Priya et al;

International Society for Fluoride Research; FLUORIDE 30 (1)1997, pp 51 - 58

(_http://www.fluoride-journal.com/97-30-1_

(http://www.fluoride-journal.com/97-30-1) ...)

 

Professor I.M. Trakhtenberg. Trakhtenberg, I.M. From Russian translation.

Chronic Effects of Mercury on Organisms. In Place of a Conclusion Thiol

poisons, especially mercury and its compounds, reacting with SH groups of

proteins

lead to the lowered activity of various enzymes containing sulfhydryl groups.

This produces a series of disruptions in the functional activity of many

organs and tissues of the organism.

 

Timoshina IV, Liubchenko PN, Khzardzhian VG. Ter Arkh. 1985;57(2):91-5.

[Article in Russian] Examination of the exocrine function of the pancreas in 52

workers exposed to lead, including 36 with the symptoms of intoxication (mild

in 33 and marked in 3) revealed the primarily hyposecretory response of

acinar cells stimulated with pancreozymin and secretin, while the hyposecretory

and dyspancreatic responses were recorded less frequently. The endocrine

function of the pancreas was revealed to be also lowered, which was confirmed

by

the decreased blood fasting insulin content and low blood insulin content after

glucose intake as well. The changes in pancreatic function are among the

pathogenetic mechanisms of the abdominal syndrome observable during lead

intoxication.

 

Shirng-Wern Tsaih et al. Lead, Diabetes, Hypertension, and Renal Function:

The Normative Aging Study. Harvard Medical School, Boston, Massachusetts.

Environmental Health Perspectives Volume 112, Number 11, August 2004

 

Cadmium sources: Tap water, fungicides, marijuana, processed meat, rubber,

seafood (cod, haddock, oyster, tuna), sewage, tobacco, colas (especially from

vending machines), tools, welding material, evaporated milk, airborne

industrial contaminants, batteries, instant coffee, incineration of

tires/rubber/plastic, refined grains, soft water, galvanized pipes, dental

alloys, candy,

ceramics. Increasing rates of type 2 diabetes worldwide suggest that diabetes

may be caused by environmental toxins. Cadmium is a widespread environmental

pollutant that accumulates in the pancreas and exerts diabetogenic effects in

animals. To test the hypothesis that exposure to cadmium is associated with

impaired fasting glucose and type 2 diabetes, we examined the associations

between urinary cadmium and the prevalence of impaired fasting glucose

(prediabetes) and diabetes in the Third National Health and Nutrition

Examination

Survey (NHANES III). In this large cross-sectional study, urinary cadmium

levels

are significantly and dose-dependently associated with both impaired fasting

glucose and diabetes. These findings, which require confirmation in

prospective studies, suggest that cadmium may cause prediabetes and diabetes in

humans.

Urinary cadmium, impaired fasting glucose, and diabetes in the NHANES III

Pathophysiology/Complications - National Health and Nutrition Examination

Survey Diabetes Care, Feb, 2003

 

Vandiver J, " Chicken Feed, " Daily Times (Salisbury, Md.), January 4, 2004

 

Tseng CH, Tseng CP, Chiou HY, Hsueh YM, Chong CK, Chen CJ. Epidemiologic

evidence of diabetogenic effect of arsenic. Toxicol Lett. 2002 Jul

7;133(1):69-76.

 

Tseng CH, Tseng CP, Chiou HY, Hsueh YM, Chong CK, Chen CJ. Epidemiologic

evidence of diabetogenic effect of arsenic. Toxicol Lett. 2002 Jul

7;133(1):69-76.

 

Mahfuzar Rahman et al. Division of Occupational and Environmental Medicine,

Department of Health and Environment, Faculty of Health Science Linkoping

University Sweden. Department of Occupational and Environmental Health(DOEH),

National Institute of Preventive and Social Medicine (NIPSOM), Mohakhali,

Dhaka-1212 Bangladesh. American Journal of Epidemiology 1998; Vol. 148, No.2:

198-203 The crude prevalence ratio for diabetes mellitus among keratotic

subjects

exposed to arsenic was 4.4 (95% confidence interval 2.5-7.7) and increased

to 5.2 (95% confidence interval 2.5-10.5) after adjustment for age, sex, and

body mass index (_http://www.ehponline.org/docs/2003/6407_

(http://www.ehponline.org/docs/2003/6407) ...) .

 

Lasky T, Sun W, Kadry A, Hoffman MK. Mean total arsenic concentrations in

chicken 1989-2000 and estimated exposures for consumers of chicken. Office of

Public Health and Science, Food Safety and Inspection Service, U.S. Department

of Agriculture, Washington, DC, USA.

 

Tseng CH, Tseng CP, Chiou HY, Hsueh YM, Chong CK, Chen CJ. Epidemiologic

evidence of diabetogenic effect of arsenic. Toxicol Lett. 2002 Jul

7;133(1):69-76.

 

A solution of alloxan at 2% diluted in saline at 0.9% was administered to

the animals in a single dose corresponding to 40 mg of alloxan per kg of animal

weight injected into their penial vein. Alloxan induces irreversible

diabetes mellitus after 24 hours following its administration and the condition

proves to be chronic by laboratory tests after seven days. Experimental Model

of

Induction of Diabetes Mellitus in Rats; Acta Cir. Bras. vol.18 no.spe S o

Paulo 2003 (_www.scielo.br/scielo.php?pid=S0102-8650_

(http://www.scielo.br/scielo.php?pid=S0102-8650) ...)

 

Researchers who are studying diabetes commonly use the chemical to induce

the disorder in lab animals. Unfortunately, most consumers are unaware of

alloxan and its potentially fatal link to diabetes because these facts are not

well publicized, are hidden by FDA approval, and certainly doctors and the food

industry are not informing parents that they and their children are being

poisoned by white flour containing alloxan. Diabetes and Chemical Poisoning.

(_http://imva.info/_ (http://imva.info/) )

 

Consumer Reports (Feb. 2006): (_http://www.curezone.com/foods/aspartame.html_

(http://www.curezone.com/foods/aspartame.html) )

 

(_http://www.elpais.es/articulo/elpsalpor_

(http://www.elpais.es/articulo/elpsalpor) ...)

 

Genetically Engineered Food Biotech, Biotechnology, GMO, Genetically

Modified (_http://www.organicconsumers.org/gelink.html_

(http://www.organicconsumers.org/gelink.html) )

 

Health Hazards of Genetically Manipulated Foods;

(_http://www.soyinfo.com/haz/gehaz.shtml_

(http://www.soyinfo.com/haz/gehaz.shtml) )

 

Dr. Irina Ermakova added flour from a GM soya bean -- produced by Monsanto

to be resistant to its pesticide, Roundup -- to the food of female rats,

starting two weeks before they conceived, continuing through pregnancy, birth

and

nursing. Others were given non-GM soya and a third group was given no soya at

all. She found that 36 per cent of the young of the rats fed the modified

soya were severely underweight, compared to 6 per cent of the offspring of the

other groups. More alarmingly, a staggering 55.6 per cent of those born to

mothers on the GM diet perished within three weeks of birth, compared to 9 per

cent of the offspring of those fed normal soya, and 6.8 per cent of the young

of those given no soya at all. (_http://www.organicconsumers.org/ge/babi_

(http://www.organicconsumers.org/ge/babi) ...)

 

Malatesta M, Caporaloni C, Rossi L, Battistelli S, Rocchi MBL, Tonucci F,

Gazzanelli G (2002) Ultrastructural analysis of pancreatic acinar cells from

mice fed on genetically modified soybean. Journal of Anatomy 201:409-415

 

Agency for Toxic Substance and Dissease Registry

(_http://www.atsdr.cdc.gov/NER/BENZENE/be_

(http://www.atsdr.cdc.gov/NER/BENZENE/be) ...) Foods

Containing Benzene (level is ug/kg, where available)

 

Vegetables

 

* Dry red beans

 

* Leek

 

* Mushroom

 

* Onion, roasted

 

* Parsley

 

* Potato, cooked peel

 

* Soybean milk

 

* Trassi, cooked

 

Beverages

 

* Cocoa

 

* Coffee

 

* Jamaican rum (120)

 

* Tea

 

* Whiskey

 

Fruits

 

* Apple

 

* Citrus fruit

 

* Cranberry and bilberry

 

* Black currants

 

* Guava

 

* Cayenne pineapple

 

* Strawberry (trace)

 

* Tomato, hothouse

 

Dairy products

 

* Butter (0.5)

 

* Blue cheese

 

* Cheddar cheese

 

* Other cheese

 

Meat, Fish, and Poultry

 

* Cooked beef (2-19)

 

* Irradiated beef (19)

 

* Cooked chicken (<10)

 

* Egg, hard-boiled (500-1900)

 

* Egg, uncooked (2100)

 

* Haddock fillet (100 to 200)

 

* Lamb, heated (<10)

 

* Mutton, heated (<10)

 

* Veal, heated (<10)

 

* Codfish

 

Nuts

 

* Filbert, roasted

 

* Peanut, roasted

 

* Macadamia nut

 

Soft Drinks, Diet And Regular, Linked To Increase In Risk Factors For Heart

Disease; 26 Jul 2007 (_http://www.medicalnewstoday.com/article_

(http://www.medicalnewstoday.com/article) ...)

 

Journal Diabetes Care. February 2004

 

Lau K, McLean WG, Williams DP, Howard CV. Synergistic Interactions Between

Commonly Used Food Additives in a Developmental Neurotoxicity Test. Toxicol

Sci. 2005 Dec 13; (_http://www.ncbi.nlm.nih.gov/entrez/quer_

(http://www.ncbi.nlm.nih.gov/entrez/quer) ...)

 

U.S. Environmental Protection Agency’s Current Safety Threshold for

Bisphenol A. The current safety threshold established by the U.S. EPA -- called

the

reference dose (i.e., safe dose) -- was set based on animal experiments

conducted prior to 1988 showing that 50 milligrams per kilogram of body weight

caused weight loss in rodents. U.S. EPA declared 50 mg/kg/day the lowest

observed

adverse effect level, or LOAEL. To arrive at the current reference dose,

U.S. EPA assumed without further study that a dose 1000 times lower than the

LOAEL (i.e., 50 micrograms per kilogram per day, or 50 µg/kg/day) would be an

acceptable reference dose. As over 40 studies now illustrate, the official

reference dose of 50 µg/kg/day is well above the levels at which adverse

affects

have been found in numerous animal studies over the past decade. For example,

Dr. Kembra Howdeshell and her colleagues found that the female offspring of

pregnant mice fed bisphenol A at the low dose of 2.4 micrograms per kilogram

per day experienced the early onset of puberty. If U.S. EPA were to use 2.4

µg/kg/day as a LOAEL and apply the same logic used to establish the current

standard, thereference dose would be 2.4 nanograms per kilogram per day

(ng/kg/day). A reference dose of 2.4 ng/kg/day would eliminate commercial uses

of

bisphenol A in food and beverage containers and products that babies are likely

to put in their mouths.

(_http://www.telegraph.co.uk/news/main.jh_

(http://www.telegraph.co.uk/news/main.jh) ...)

 

American Diabetes Association: Diabetes Facts and Figures [factsheet online]

1997 [cited August 1999][16 screens].

 

CDC. (_http://www.cdc.gov/diabetes/pubs/pdf/nd_

(http://www.cdc.gov/diabetes/pubs/pdf/nd) ...)

 

Brancati FL, Wang NY, Mead LA, Liang KY, Klag MJ. Body weight patterns from

20 to 49 years of age and subsequent risk for diabetes melli-tus. Arch Intern

Med 1999;159:957-963.

 

Kopelman PG, Hitman GA. Exploding type II [correspondence]. Lancet

1998;352:SIV5.

 

HIV/AIDS Surveillance Report 2003;15. The finding is being reported in the

journal Nature Genetics by researchers at Decode Genetics, a company in

Reykjavik, Iceland, that specializes in finding the genetic roots of human

diseases. January 16, 2006

 

Saldana TM, O Basso, JA Hoppin, DD Baird, C Knott, A Blair, MC Alavanja and

DP Sandler. 2007. Pesticide exposure and self-reported gestational diabetes

mellitus in the Agricultural Health Study. Diabetes Care. 30(3):529-34.

(_http://www.environmentalhealthnews.org/_

(http://www.environmentalhealthnews.org/)

....)

 

GreenFacts Digest on Phthalates - Phthalates and Metabolism: Exposure

Correlates with Obesity and Diabetes in Men; Melissa Lee Phillips; Environ

Health

Perspect. 2007 June; 115(6): A312.

 

New Zealand sawmill workers’ health problems caused by chemical poisoning;

(_http://www.wsws.org/articles/2002/aug20_

(http://www.wsws.org/articles/2002/aug20) ...)

 

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