RE: UCLA Curcumin Alzheimer's Breakthrough?

[Guest guest]

Hi GB,

 

Those were my questions too, I contacted Verdure Sciences about it this morning

(Blake Ebersole, bebersole) and he said it was found to clear

amyloid from Alzheimer's models better than anything they have tested including

unformulated curcumin, and is currently being used in several studies including

cancer and Alzheimer's. It is available for sale if you contact them directly,

however he said its not found on the shelves yet.

 

Apparently there is a multistep process using lipids, phospholipids, and

antioxidant stabilizers to coat the curcumin to protect it from degrading in the

stomach, and help it absorb through the GI tract into the bloodstream and

particular organs such as the brain.

 

I am buying some for my mother who has Alzheimer's, keep fingers crossed.

 

Curt

 

 

 

: greatyoga:

Sat, 13 Sep 2008 19:27:50 +0000<< >> Re:

UCLA Curcumin Alzheimer's Breakthrough?

 

 

 

 

Curtis,I am not a scientist so had a hard time reading the link, etc. Is this on

the market? Also, how would eating the actual turmeric root work?ThanksGB--- In

, " curtsummerlin " <curtsummerlin

wrote:>> I know that curcumin's limitations for viable treatment is >

bioavailability. In humans they havent achieved more than 0.1uM free > curcumin

in plasma even with piperine at like 12 grams per day, but > here they report

5uM, like 50x greater. Could this be true? See >

http://www.ncbi.nlm.nih.gov/pubmed/18417733> > " Oral gavage of an optimized

lipidated curcumin formulation (Verdure > Sciences, Noblesville, Indiana)

resulted in 11-fold higher levels of > curcumin in plasma and 4-fold higher

levels in brain compared to > equal doses of curcumin powder or

curcumin-piperine extracts. A 5 mg > curcumin dose delivered by acute gavage in

this lipid rich > formulation (n=5) resulted in 2.15 ± 0.744 µM mouse brain

curcumin > levels after 3 hrs. After 2 weeks lipidated formulation at 500 ppm >

curcumin in chow (n=5) we observed 5.79 ± 1.22 µM mouse brain > curcumin, well

above the 1-2 µM range of EC50's for the inhibition of > iNOS, IL-1ß, PGE2 and

isoprostanes. This suggests oral delivery can > achieve our target tissue

levels. " > > http://www.ncbi.nlm.nih.gov/pubmed/18417733> > Am I reading this

right?> > Curtis> > " Anyone who has never made a mistake has never tried

anything new. " - > Einstein>

 

 

 

 

 

_______________

Want to do more with Windows Live? Learn “10 hidden secrets” from Jamie.

http://windowslive.com/connect/post/jamiethomson.spaces.live.com-Blog-cns!550F68\

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[Guest guest]

The following is part of Dr Jim Howenstine's article " Is Psychiatry

Scientific and Dangerous " .

 

http://www.newswithviews.com/Howenstine/james58.htm

 

*

*

 

*What Is Avea?*

 

Turmeric (curcumin) has long been used in Ayurvedic and Chinese medicine as

an anti-inflammatory, to treat digestive disorders and liver problems and

for the treatment of skin diseases and wound healing. Curcumin stimulates

the production of bile and facilitates emptying of the gall bladder. In

animals curcumin protects the liver, has anti-tumor action, reduces

inflammation and fights some infections.

 

Avea is an extract from the root of Curcuma longa, commonly know as

turmeric. Nutramedix has a proprietary formulation of curcumin that is more

effective than conventional curcumin because of special extraction and

enhancement techniques.

 

The German Commission E reports that curcumin has no known

contraindications, no known side effects and no known interactions with

other drugs. In May 2005, toxicology studies were completed on Avea at the

University of Guayaquil, Ecuador. No toxic effects were seen even when the

animals were given doses 160,000 times the equivalent human dose.

 

*Patients suffering from depression often report relief from depression

within a few hours to a few days after starting Avea*. A 38 year old woman

had been seriously depressed for more than ten years despite therapy with

several different pharmaceutical drugs. When started on her first dose of

Avea she felt less depressed after thirty minutes. The depression was gone

in 24 hours but the therapy was continued.

 

The dosage of Avea is ten to twelve drops three or four times daily.

Patients who respond rapidly to Avea should remain on this therapy for one

to two months to allow the body to reset neurochemical balances in the

brain. Patients who have been taking SSRI drugs should slowly taper off SSRI

therapy over many weeks if they wish to terminate SSRI therapy.

 

We think that persons trying Avea for depression will be pleased with this

safe rapidly acting therapy. Avea can be obtained from

naturalhealthteam.comphone 1-800-416-2806 and from

nutramedix.com phone 1-561-745-2917.

 

 

On Sat, Sep 13, 2008 at 8:27 PM, Guru K <greatyoga wrote:

 

> Curtis,

>

> I am not a scientist so had a hard time reading the link, etc. Is

> this on the market? Also, how would eating the actual turmeric root

> work?

>

> Thanks

> GB

>

> --- In

<%40gro\

ups.com>,

> " curtsummerlin "

> <curtsummerlin wrote:

> >

> > I know that curcumin's limitations for viable treatment is

> > bioavailability. In humans they havent achieved more than 0.1uM

> free

> > curcumin in plasma even with piperine at like 12 grams per day, but

> > here they report 5uM, like 50x greater. Could this be true? See

> > http://www.ncbi.nlm.nih.gov/pubmed/18417733

> >

> > " Oral gavage of an optimized lipidated curcumin formulation

> (Verdure

> > Sciences, Noblesville, Indiana) resulted in 11-fold higher levels

> of

> > curcumin in plasma and 4-fold higher levels in brain compared to

> > equal doses of curcumin powder or curcumin-piperine extracts. A 5

> mg

> > curcumin dose delivered by acute gavage in this lipid rich

> > formulation (n=5) resulted in 2.15 ± 0.744 µM mouse brain curcumin

> > levels after 3 hrs. After 2 weeks lipidated formulation at 500 ppm

> > curcumin in chow (n=5) we observed 5.79 ± 1.22 µM mouse brain

> > curcumin, well above the 1-2 µM range of EC50's for the inhibition

> of

> > iNOS, IL-1ß, PGE2 and isoprostanes. This suggests oral delivery can

> > achieve our target tissue levels. "

> >

> > http://www.ncbi.nlm.nih.gov/pubmed/18417733

> >

> > Am I reading this right?

> >

> > Curtis

> >

> > " Anyone who has never made a mistake has never tried anything new. "

> -

> > Einstein

> >

>

>

>