Heart Disease - The Potbelly Syndrome:

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Heart Disease

 

There are several germs that attack our arteries and our immune systems at

the same time. The best known of these germs are Chlamydophila pneumoniae

(CPN) a bacterium, and cytomegalovirus (CMV), a herpes virus. When we are

infected with either of these germs, or by germs like them, we will eventually

d

evelop cardiovascular disease. The drawing shows how it happens.

 

 

 

 

 

 

 

 

Germs, foam cells, and heart disease are discussed in Chapter 4 of The

Potbelly Syndrome.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

More infomation on heart disease

 

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Concurrent increased high sensitivity C-reactive protein and chronic infections

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associated with coronary artery disease: a population-based study. Indian J

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M._

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ltsPanel.Pubmed_RVDocSum) [Periodontal disease and cardiovascular disease:

correlation or simple coincidence?]

Recenti Prog Med. 2007 Jul-Aug;98(7-8):426-32. Review. Italian.

 

_Mahmoudi M, Curzen N, Gallagher PJ._

(http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=ShowDetailView & TermToSea\

rch=17394488 & ordinalpos=26 & itool=Entre

zSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum) Atherogenesis:

the role of inflammation and infection. Histopathology. 2007

Apr;50(5):535-46. Review.

 

 

_Higuchi ML, Santos MH, Roggerio A, Kawakami JT, Bezerra HG, Canzian M._

(http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=ShowDetailView & TermToSea\

rc

h=17072447 & ordinalpos=3 & itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel

..Pubmed_RVDocSum) A role for archaeal organisms in development of

atherosclerotic vulnerable plaques and myxoid matrices. Clinics. 2006

Oct;61(5):473-8.

 

 

_Clancy R, Ren Z, Pang G, Fletcher P, D'Este C._

(http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=ShowDetailView & TermToSea\

rch=17034570 & ordinalpos=76 &

itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum)

Chronic Chlamydia pneumoniae infection may promote coronary artery disease in

humans through enhancing secretion of interleukin-4. Clin Exp Immunol. 2006

Nov;146(2):197-202.

_Cao F, Castrillo A, Tontonoz P, Re F, Byrne GI._

(http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=ShowDetailView & TermToSea\

rch=17145941 & ordinalpos=1

& itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum)

Chlamydia pneumoniae--induced macrophage foam cell formation is mediated by

Toll-like receptor 2. Infect Immun. 2007 Feb;75(2):753-9. Epub 2006 Dec 4.

 

 

_Paoletti R, Gotto AM Jr, Hajjar DP._

(http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=ShowDetailView & TermToSea\

rch=15198962 & ordinalpos=2 & itool=Entre

zSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum) Inflammation in

atherosclerosis and implications for therapy. Circulation. 2004 Jun

15;109(23 Suppl 1):III20-6. Review.

_Ewald PW, Cochran GM._

(http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=ShowDetailView & TermToSea\

rch=10839723 & ordinalpos=8 & itool=EntrezSystem2.PEntr

ez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum) Chlamydia pneumoniae and

cardiovascular disease: an evolutionary perspective on infectious causation and

antibiotic treatment. J Infect Dis. 2000 Jun;181 Suppl 3:S394-401. Review.

 

 

_Likhoded VG, Martynova VR._

(http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=ShowDetailView & TermToSea\

rch=12712533 & ordinalpos=10 & itool=EntrezSystem2

..PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum) [Role of Chlamydia

pneumoniae in the etiology of atherosclerosis] Zh Mikrobiol Epidemiol

Immunobiol.

2000 Jul-Aug;(4 Suppl):117-21. Review. Russian.

_Zhou YF, Guetta E, Yu ZX, Finkel T, Epstein SE._

(http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed & Cmd=ShowDetailView & TermToSea\

rch=8903333 & ordinalpos=7 &

itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum)

Human cytomegalovirus increases modified low density lipoprotein uptake and

scavenger receptor mRNA expression in vascular smooth muscle cells. J Clin

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1996 Nov 1;98(9):2129-38.

 

The Potbelly Syndrome:

How Common Germs cause Obesity, Diabetes, and Heart Disease

_http://www.potbellysyndrome.com/index_010.htm_

(http://www.potbellysyndrome.com/index_010.htm)