SAFETY OF SODIUM BICARBONATE AND ITS USE IN OTHER PATHOLOGIES

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SAFETY OF SODIUM BICARBONATE AND ITS USE IN OTHER PATHOLOGIES

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Doses of sodium bicarbonate at 5%, as indicated in the Simoncini treatment

are innocuous. In fact they have been used without any problems for over 30

years in a multitude of other deseases such as:

 

* Severe diabetic ketoacidosis (1)

* Cardiopulmonary resuscitation (2)

* Pregnancy (3)

* Hemodialysis (4)

* Peritoneal dialysis. (5)

* Pharmacological toxicosis. (6)

* Hepatopathy. (7)

* Vascular surgery operations (8)

 

1. Gamba, G., “Bicarbonate therapy in severe diabetic ketoacidosis. A

double blind, randomized, placebo controlled trial.†(Rev Invest Clin 1991

Jul-Sep;43(3):234-8). Miyares Gomez A. in “Diabetic ketoacidosis in

childhood: the

first day of treatment (An Esp Pediatr 1989 Apr;30(4):279-83).

2. Levy, M.M., “An evidence-based evaluation of the use of sodium

bicarbonate during cardiopulmonary resuscitation†(Crit Care Clin 1998

Jul;14(3):457-83). Vukmir, R.B., Sodium bicarbonate in cardiac arrest: a

reappraisal (Am J

Emerg Med 1996 Mar;14(2):192-206). Bar-Joseph, G., “Clinical use of sodium

bicarbonate during cardiopulmonary resuscitation--is it used sensibly?â€

(Resuscitation 2002 Jul;54(1):47-55).

3. Zhang. L.,“Perhydrit and sodium bicarbonate improve maternal gases and

acid-base status during the second stage of labor†Department of Obstetrics

and Gynecology, Xiangya Hospital, Hunan Medical University, Changsha 410008.

Maeda, Y., “Perioperative administration of bicarbonated solution to a

patient with mitochondrial encephalomyopathy†(Masui 2001 Mar;50(3):299-303).

4. Avdic. E., “Bicarbonate versus acetate hemodialysis: effects on the

acid-base status†(Med Arh 2001;55(4):231-3).

5. Feriani, M., “Randomized long-term evaluation of bicarbonate-buffered

CAPD solution.†(Kidney Int 1998 Nov;54(5):1731-8).

6. Vrijlandt, P.J., “Sodium bicarbonate infusion for intoxication with

tricyclic antidepressives: recommended inspite of lack of scientific

evidenceâ€

Ned Tijdschr Geneeskd 2001 Sep 1;145(35):1686-9). Knudsen, K., “Epinephrine

and sodium bicarbonate independently and additively increase survival in

experimental amitriptyline poisoning.†(Crit Care Med 1997 Apr;25(4):669-74).

7. Silomon, M., “Effect of sodium bicarbonate infusion on hepatocyte Ca2+

overload during resuscitation from hemorrhagic shock.†(Resuscitation 1998

Apr;37(1):27-32). Mariano, F., “Insufficient correction of blood bicarbonate

levels in biguanide lactic acidosis treated with CVVH and bicarbonate

replacement fluids†(Minerva Urol Nefrol 1997 Sep;49(3):133-6).

8. Dement'eva, I.I., “Calculation of the dose of sodium bicarbonate in

the treatment of metabolic acidosis in surgery with and deep hypothermic

circulatory arrest†(Anesteziol Reanimatol 1997 Sep-Oct;(5):42-4).

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