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Metabolic indicators hold key to preventing diabetes and heart disease

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Metabolic indicators hold key to preventing diabetes and heart disease

_http://www.rocklintoday.com/news/templates/diabetes_information.asp?articleid

=5921 & zoneid=53_

(http://www.rocklintoday.com/news/templates/diabetes_information.asp?articleid=5\

921 & zoneid=53)

 

 

Insulin resistance and metabolic syndrome are at the heart of both type 2

diabetes and cardiovascular disease.

Dr. SM Grundy, MD, PhD, at the University of Texas Southwestern Medical

Center, believes that, “approximately one-third of an apparently healthy

population is sufficiently insulin-resistant to be at increased risk to develop

type

2 diabetes, cardiovascular disease, high blood pressure, polycystic ovary

disease, nonalcoholic liver disease and others.â€

Focusing on metabolic syndrome, he states, will have the greatest impact on

reducing the risk for cardiovascular disease.

Metabolic syndrome is usually defined as: waist circumference over 35 inches

for women and 40 for men, fasting glucose over 100 mg/dL, blood pressure

over 130/85, triglycerides over 150 mg/dL, HDL cholesterol less than 50 mg/dL

for women and less than 40 mg/dL for men. Often, proinflammatory and

prothrombotic factors are also considered, measured as elevated hs-CRP and

fibrinogen,

respectively.

To recognize the presence of metabolic syndrome and dysfunctional insulin

signaling - before organs are damaged and a definitive disease takes place -

Dr. Jeff Bland, PhD, FACN, FACB suggests that the best early-stage marker

associated with insulin resistance is the shift of the apolipoprotein B and

apoliprotein A-1 levels in the serum.

Apolipoprotein B is the primary apolipoprotein of low density lipoproteins

(LDL or " lousy cholesterol " ), which carries cholesterol to tissues.

Apolipoprotein A-I is the major protein component of high density lipoprotein

(HDL or “

good cholesterol) in plasma that promotes cholesterol being excreted out of

the body by the liver. These lipoproteins are affected by not only genes,

but by diet, lifestyle, and environmental factors.

It has been well-documented that an elevated apolipoprotein B to

apolipoprotein A-1 ratio is an important determinant of cardiovascular disease

risk -

independent of total serum cholesterol levels.

Dr Bland suggests that Apo B/apo A-1 ratio may be the most useful summary

index of cardiovascular risk and that it is more helpful than the

conventionally used LDL-cholesterol measurements and various other lipid

ratios. The

advantage also of the apo B/apo A-1 ratio is that it can be determined in

non-fasting blood, unlike other cholesterol tests.

The lower the ratio, the lower the risk. A ratio of apo B/apo A-1 of 0.7

or lower would be considered a lower risk, whereas a ratio of 0.8 or higher

would represent an increased risk.

More importantly, the apo B/apo A-1 is a very sensitive indicator of the

change in insulin signaling and provides an early warning of the risk

associated

with metabolic syndrome, often leading to heart disease and type 2 diabetes.

 

 

 

 

 

 

 

 

Dr. Dennis Godby, Doctor of Naturopathy, Sutter Medical Foundation.

He may be reached _online_

(http://www.rocklintoday.com/sendlink.asp?site=6600) or at his Sacramento

Office (916) 446-2591

 

Dr Godby is also the the author of

_The Practical Guide to Overcoming Diabetes Naturally_

(http://www.endtodiabetes.com/)

 

 

 

 

 

 

 

 

 

 

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Please frind atached my lab report in April 08 and Aug o6

 

FBS 108mg%

116mg%

 

PPBS 136mg%

160mg%

 

Cholestrole SERUM 216mg% 236mg%

 

TRGLYCERIDE 91mg%

 

HDL 57mg%

49mg%

 

LDL 141mg%

163mg%

 

In the morning I walk about 30- 40 mts.Take 0.5 TS organic tumeric in 1

TS cocunut 0il, both home made, 10 drops DIABONIL, a Homeo preparatin

for Diabetics, 30 mts prior to food 3 times daily.LDL is still high. Any

NATURAL MEDICINE to reduce LDL please. I am 63, a retired Engineer.

 

Sincerely yours

 

P.K.Philip

 

 

 

 

>

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