Magnesium and Cancer

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Magnesium and Cancer

_http://www.magnesiumforlife.com/index_references.shtml_

(http://www.magnesiumforlife.com/index_references.shtml)

Magnesium stabilizes ATP__

(http://www.magnesiumforlife.com/index_references.shtml#_edn1) , allowing

DNA and RNA transcriptions and repairs._[ii]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn2)

There is a power and a force in magnesium that cannot be equaled anywhere

else in the world of medicine. There is no substitute for magnesium in human

physiology; nothing comes even close to it in terms of its effect on overall

cell physiology. Without sufficient magnesium, the body accumulates toxins and

acid residues, degenerates rapidly, and ages prematurely. It goes against a

gale wind of medical science to ignore magnesium chloride used transdermally in

the treatment of any chronic or acute disorder, especially cancer.

Magnesium repletion produced rapid

disappearance of the periosteal tumors._[iii]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn3)

Aleksandrowicz et al in Poland conclude that inadequacy of Mg and

antioxidants are important risk factors in predisposing to leukemias._[iv]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn4) Other

researchers found

that 46% of the patients admitted to an ICU in a tertiary cancer center

presented hypomagnesemia. They concluded that the incidence of hypomagnesemia

in

critically ill cancer patients is high._[v]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn5) In animal

studies we find that Mg deficiency has

caused lymphopoietic neoplasms in young rats. A study of rats surviving Mg

deficiency sufficient to cause death in convulsions during early infancy in

some, and cardiorenal lesions weeks later in others, disclosed that some of

survivors had thymic nodules or lymphosarcoma._[vi]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn6)

One would not normally think that Magnesium (Mg) deficiency can

paradoxically increase the risk of, or protect against cancer yet we will find

that just

as severe dehydration or asphyxiation can cause death magnesium deficiency can

directly lead to cancer. When you consider that over 300 enzymes and ion

transport require magnesium and that its role in fatty acid and phospholipids

acid metabolism affects permeability and stability of membranes, we can see

that magnesium deficiency would lead to physiological decline in cells setting

the stage for cancer. Anything that weakens cell physiology will lead to the

infections that surround and penetrate tumor tissues. These infections are

proving to be an integral part of cancer. Magnesium deficiency poses a direct

threat to the health of our cells. Without sufficient amounts our cells

calcify and rot in. Breeding grounds for yeast and fungi colonies they become,

invaders all to ready to strangle our life force and kill us.

Over 300 different enzymes systems rely upon magnesium to facilitate their

catalytic action, including ATP metabolism, creatine-kinase activation,

adenylate-cyclase, and sodium-potassium-ATPase._[vii]_

(http://www.magnesiumforlife

..com/index_references.shtml#_edn7)

It is known that carcinogenesis induces magnesium distribution disturbances,

which cause magnesium mobilization through blood cells and magnesium

depletion in non-neoplastic tissues. Magnesium deficiency seems to be

carcinogenic,

and in case of solid tumors, a high level of supplemented magnesium inhibits

carcinogenesis._[viii]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn8) Both

carcinogenesis and magnesium deficiency increase the plasma

membrane permeability and fluidity. Scientists have in fact found out that

there is much less Mg++ binding to membrane phospholipids of cancer cells, than

to normal cell membranes._[ix]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn9)

Magnesium protects cells from aluminum,

mercury, lead, cadmium, beryllium and nickel.

Magnesium in general is essential for the survival of our cells but takes on

further importance in the age of toxicity where our bodies are being

bombarded on a daily basis with heavy metals. Glutathione requires magnesium

for its

synthesis._[x]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn10) Glutathione

synthetase requires γ-glutamyl cysteine, glycine, ATP, and

magnesium ions to form glutathione._[xi]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn11) In magnesium

deficiency, the enzyme y-glutamyl

transpeptidase is lowered._[xii]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn12) According to

Dr. Russell Blaylock, low magnesium is

associated with dramatic increases in free radical generation as well as

glutathione

depletion and this is vital since glutathione is one of the few antioxidant

molecules known to neutralize mercury._[xiii]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn13) Without the

cleaning and chelating work of

glutathione (magnesium) cells begin to decay as cellular filth and heavy

metals accumulates; excellent environments to attract deadly infection/cancer.

There is drastic change in ionic flux from the outer

and inner cell membranes both in the impaired

membranes of cancer, and in Mg deficiency.

Anghileri et al_[xiv]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn14) ,_[xv]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn15) proposed that

modifications of cell membranes are principal triggering

factors in cell transformation leading to cancer. Using cells from induced

cancers, they found that there is much less magnesium binding to membrane

phospholipids of cancer cells, than to normal cell membranes._[xvi]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn16) It has been

suggested

that Mg deficiency may trigger carcinogenesis by increasing membrane

permeability._[xvii]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn17)

Magnesium deficient cells membranes seem to have a smoother surface than

normal, and decreased membrane viscosity, analogous to changes in human

leukemia

cells._[xviii]_ (http://www.magnesiumforlife.com/index_references.shtml#_edn18)

,_[xix]_ (http://www.magnesiumforlife.com/index_references.shtml#_edn19)

There is drastic change in ionic flux from the outer and inner cell membranes

(higher Ca and Na; lower Mg and K levels), both in the impaired membranes of

cancer, and of Mg deficiency. And we find that lead (Pb) salts, are more

leukemogenic when given to Mg deficient rats, than when they are given to

Mg-adequate rats, suggesting that Mg is protective._[xx]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn20)

Magnesium has an effect on a variety of cell membranes

through a process involving calcium channels and ion transport mechanisms.

Magnesium is responsible for the maintenance

of the trans-membrane gradients of sodium and potassium.

Long ago researchers postulated that magnesium supplementation of those who

are Mg deficient, like chronic alcoholics, might decrease emergence of

malignancies_[xxi]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn21)

and now modern researchers have found that all types of alcohol — wine, beer

or liquor — add equally to the risk of developing breast cancer in women.

The researchers, led by Dr. Arthur Klatsky of the Kaiser Permanente Medical

Care Program in Oakland, Calif., revealed their findings at a meeting of the

European Cancer Organization in Barcelona in late 2007. It was found that women

who had one or two drinks a day increased their risk of developing breast

cancer by 10 percent. Women who had more than three drinks a day raised their

risk by 30 percent. The more one drinks the more one drives down magnesium

levels.

Breast cancer is the second most common cancer

killer of women, after lung cancer. It will be diagnosed in

1.2 million people globally this year and will kill 500,000.

According to data published in the British Journal of Cancer in 2002, 4

percent of all breast cancers — about 44,000 cases a year — in the United

Kingdom are due to alcohol consumption. It’s an important question though,

and one

not asked by medical or health officials, is it the alcohol itself or the

resultant drop in magnesium levels that is cancer provoking? Though some

studies

have shown that light- to moderate alcohol use can protect against heart

attacks it does us no good to drink if it cause cancer. Perhaps if magnesium

was

supplemented in women drinkers who were studied there would have been no

increase of cancer from drinking.

Alcohol has always been known to deplete magnesium,

and is one of the first supplements given to alcoholics

when they stop and attempt to detoxify and withdraw.

Researchers from the School of Public Health at the University of Minnesota

have just concluded that diets rich in magnesium reduced the occurrence of

colon cancer._[xxii]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn22) A previous

study from Sweden_[xxiii]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn23) reported that

women with the highest

magnesium intake had a 40 per cent lower risk of developing the cancer than

those

with the lowest intake of the mineral.

Pre-treatment hypomagnesemia has been reported

in young leukemic children, 78% of whom have histories

of anorexia, and have excessive gut and urinary losses of Mg._[xxiv]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn24)

Several studies have shown an increased cancer rate in regions with low

magnesium levels in soil and drinking water, and the same for selenium. In

Egypt

the cancer rate was only about 10% of that in Europe and America. In the

rural fellah it was practically non-existent. The main difference was an

extremely high magnesium intake of 2.5 to 3g in these cancer-free populations,

ten

times more than in most western countries._[xxv]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn25)

The School of Public Health at the Kaohsiung Medical College in,

Taiwan, found that magnesium also exerts a protective effect

against gastric cancer, but only for the group with the highest

levels._[xxvi]_ (http://www.magnesiumforlife.com/index_references.shtml#_edn26)

If we looked it would probably be very difficult to find a cancer patient

with anywhere near normal levels of cellular magnesium meaning cancer probably

does not exist in a physical cellular environment full of magnesium. It makes

perfect medical sense to saturate the body with magnesium through

transdermal means. Magnesium deficiency has been implicated in a host of

clinical

disorders but the medical establishment just cannot get it through its thick

skull

that it is an important medicine.

It is as if the collective medical profession had just pulled the plug on

medical intelligence. In fact it has done exactly this and it seems too late

for it to redefine itself, which is a tragedy. Though magnesium improves the

internal production of defensive substances, such as antibodies and

considerably improves the operational activity of white granulozytic blood

cells (shown

by Delbert with magnesium chloride), and contributes to many other functions

that insure the integrity of cellular metabolism, no one thinks to use it in

cancer as a primary treatment. It is even worse than this, the medical

establishment does not even use magnesium as a secondary treatment or even use

it

at all and gladly uses radiation and chemo therapy, both of which force

magnesium levels down further.

To not replete cellular magnesium levels would be negligent especially in

the case of cancer where a person’s life is on the line. An oncologist who

ignores his patient’s magnesium levels would be analogous to an emergency

room

physician not rushing resuscitation when a person stops breathing. If one

elects to have or has already had chemotherapy they have four times the reason

to

pay attention to a concentrated protocol aimed at replenishing full magnesium

cellular stores.

Magnesium chloride is the first and most important item in any person’s

cancer treatment strategy. Put in the clearest terms possible, our suggestion

from the first day on the Survival Medicine Cancer Protocol is to almost drown

oneself in transdermally applied magnesium chloride. It should be the first

not the last thing we think of when it comes to cancer. It takes about three to

four months to drive up cellular magnesium levels to where they should be

when treated intensely transdermally but within days patients will commonly

experience its life saving medical/healing effects. For many people whose

bodies

are starving for magnesium the experience is not too much different than for

a person coming out of a desert desperate for water. It is that basic to

life, that important, that necessary.

That same power found in magnesium that will save your life in the emergency

room during cardiac arrest, that will diminish damage of a stroke if

administered in a timely fashion is the same power that can save one’s life

if one

has cancer. All a patient has to do is pour it into their baths or spray it

right onto their bodies. What could be simpler?

Magnesium chloride, when applied directly

to the skin, is transdermally absorbed and has an

almost immediate effect on chronic and acute pain.

Special Note on Calcium and Cancer:

Experts say excessive calcium intake may be unwise in light of recent

studies showing that high amounts of the mineral may increase risk of prostate

cancer. “There is reasonable evidence to suggest that calcium may play an

important role in the development of prostate cancer,†says Dr. Carmen

Rodriguez,

senior epidemiologist in the epidemiology and surveillance research department

of the American Cancer Society (ACS). Rodriguez says that a 1998 Harvard

School of Public Health study of 47,781 men found those consuming between 1,500

and 1,999 mg of calcium per day had about double the risk of being diagnosed

with metastatic (cancer that has spread to other parts of the body) prostate

cancer as those getting 500 mg per day or less. And those taking in 2,000 mg or

more had over four times the risk of developing metastatic prostate cancer

as those taking in less than 500 mg.

Calcium and magnesium are opposites in their effects

on our body structure. As a general rule, the more

rigid and inflexible our body structure is, the

less calcium and the more magnesium we need.

Later in 1998, Harvard researchers published a study of dairy product intake

among 526 men diagnosed with prostate cancer and 536 similar men not

diagnosed with the disease. That study found a 50% increase in prostate cancer

risk

and a near doubling of risk of metastatic prostate cancer among men consuming

high amounts of dairy products, likely due, say the researchers, to the high

total amount of calcium in such a diet. The most recent Harvard study on the

topic, published in October 2001, looked at dairy product intake among 20,885

men and found men consuming the most dairy products had about 32% higher

risk of developing prostate cancer than those consuming the least.

The adverse effects of excessive calcium intake may include high blood

calcium levels, kidney stone formation and kidney complications._[xxvii]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn27) Elevated

calcium

levels are also associated with arthritic/joint and vascular degeneration,

calcification of soft tissue, hypertension and stroke, and increase in VLDL

triglycerides, gastrointestinal disturbances, mood and depressive disorders,

chronic fatigue, and general mineral imbalances including magnesium, zinc, iron

and phosphorus. High calcium levels interfere with Vitamin D and subsequently

inhibit the vitamin’s cancer protective effect unless extra amounts of

Vitamin D are supplemented._[xxviii]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn28)

Magnesium is the mineral of rejuvenation and prevents

the calcification of our organs and tissues that is

characteristic of the old-age related degeneration of our body.

Recommendations of magnesium to calcium ratios range from 1:2 to 1:1. For

those interested in preventing cancer one should look closely at the 1:1 camp

and during the first six months of treatment one should be looking at ten parts

magnesium to one part calcium. In reality one need not even count the ratio

during the first months for the only real danger of extremely high magnesium

levels comes with patients suffering from kidney failure. If one is at all

concerned about their calcium intake one should eat foods high in both calcium

and magnesium like toasted sesame seeds.

Up to 30% of the energy of cells is

used to pump calcium out of the cells.

Doctors who have used intravenous magnesium treatments know the benefits of

peaking magnesium levels, even if only temporarily. For the cancer patient

the transdermal approach combined with oral use offers the opportunity to take

magnesium levels up strongly and quickly. For emergency situations three

applications a day, for urgent two treatments would be indicated though one

strong treatment with an ounce of a natural magnesium chloride solution spread

all

over the body like a sun screen is a powerful systemic treatment.

It is medical wisdom that tells us that magnesium is actually the key to the

body's proper assimilation and use of calcium, as well as other important

nutrients. If we consume too much calcium, without sufficient magnesium, the

excess calcium is not utilized correctly and may actually become toxic, causing

painful conditions in the body. Hypocalcemia is a prominent manifestation of

magnesium deficiency in humans (Rude et al., 1976). Even mild degrees of

magnesium depletion significantly decreases the serum calcium concentration

(Fatemi et al., 1991).

Calcium requirement for men and

women is lower than previously estimated._[xxix]_

(http://www.magnesiumforlife.com/index_references.shtml#_edn29)

__

__ (http://www.magnesiumforlife.com/index_references.shtml#_ednref1) Mg2+

is critical for all of the energetics of the cells because it is absolutely

required that Mg2+ be bound (chelated) by ATP (adenosine triphosphate), the

central high energy compound of the body. ATP without Mg2+ bound cannot

create the energy normally used by specific enzymes of the body to make protein,

DNA, RNA, transport sodium or potassium or calcium in and out of cells, nor to

phosphorylate proteins in response to hormone signals, etc. In fact, ATP

without enough Mg2+ is non-functional and leads to cell death. Bound Mg2+

holds the triphosphate in the correct stereochemical position so that it can

interact with ATP using enzymes and the Mg2+ also polarizes the phosphate

backbone so that the 'backside of the phosphorous' is more positive and

susceptible

to attack by nucleophilic agents such as hydroxide ion or other negatively

charged compounds. Bottom line, Mg2+ at critical concentrations is essential

to life,†says Dr. Boyd Haley who asserts strongly that, “All

detoxification

mechanisms have as the bases of the energy required to remove a toxicant the

need for Mg-ATP to drive the process. There is nothing done in the body that

does not use energy and without Mg2+ this energy can neither be made nor

used.†Detoxification of carcinogenic chemical poisons is essential for

people

want to avoid the ravages of cancer. The importance of magnesium in cancer

prevention should not be underestimated.

_[ii]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref2)

Magnesium has a central regulatory role in the cell cycle including that of

affecting transphorylation and DNA synthesis, has been proposed as the

controller

of cell growth, rather than calcium. It is postulated that Mg++ controls the

timing of spindle and chromosome cycles by changes in intracellular

concentration during the cell cycle. Magnesium levels fall as cells enlarge

until

they reach a level that allows for spindle formation. Mg influx then causes

spindle breakdown and cell division.

_[iii]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref3)

Hunt, B.J., Belanger, L.F. Localized, multiform, sub-periosteal hyperplasia and

generalized osteomyelosclerosis in magnesium-deficient rats. Calcif. Tiss.

Res. 1972; 9:17-27.

_[iv]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref4)

Aleksandrowicz, J., Blicharski, J., Dzigowska, A., Lisiewicz, J. Leuko- and

oncogenesis in the light of studies on metabolism of magnesium and its turnover

in

biocenosis. Acta Med. Pol. 1970; 11:289-302. (abstr: Blood 1971; 37:245)

_[v]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref5) D.

Deheinzelin, E.M. Negri1, M.R. Tucci, M.Z. Salem1, V.M. da Cruz1, R.M.

Oliveira, I.N. Nishimoto and C. Hoelz. Hypomagnesemia in critically ill cancer

patients: a prospective study of predictive factors. Braz J Med Biol Res,

December

2000, Volume 33(12) 1443-1448

_[vi]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref6)

Bois, P. Tumour of the thymus in magnesium-deficient rat. Nature 1964;

204:1316.

_[vii]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref7)

Magnesium is used in the creatine-phosphate formation, activates the alkaline

phosphatase and pyrophosphatase, stabilizes nucleic acid synthesis, concerning

DNA synthesis and degradation, as well as the physical integrity of the DNA

helix, activates amino acid and protein synthesis, and regulates numerous

hormones.

_[viii]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref8)

Durlach J, Bara M, Guiet-Bara A, Collery P. Relationship between magnesium,

cancer and carcinogenic or anticancer metals. Anticancer Res. 1986

Nov-Dec;6(6):1353-61.

_[ix]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref9)

Anghileri, L.J. Magnesium concentration variations during carcinogenesis.

Magnesium Bull. 1979; 1:46-48.

_[x]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref10)

Linus Pauling Institute

_http://lpi.oregonstate.edu/infocenter/minerals/magnesium/index.html#function_

(http://lpi.oregonstate.edu/infocenter/minerals/magnesium/index.html#function)

_[xi]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref11)

Virginia Minnich, M. B. Smith, M. J. Brauner, and Philip W. Majerus.

Glutathione biosynthesis in human erythrocytes. Department of Internal

Medicine,

Washington University School of Medicine, J Clin Invest. 1971 March; 50(3):

507–

513. Abstract: The two enzymes required for de novo glutathione synthesis,

glutamyl cysteine synthetase and glutathione synthetase, have been demonstrated

in

hemolysates of human erythrocytes. Glutamyl cysteine synthetase requires

glutamic acid, cysteine, adenosine triphosphate (ATP), and magnesium ions to

form γ-glutamyl cysteine. The activity of this enzyme in hemolysates from 25

normal subjects was 0.43±0.04 μmole glutamyl cysteine formed per g hemoglobin

per min. Glutathione synthetase requires γ-glutamyl cysteine, glycine, ATP,

and

magnesium ions to form glutathione. The activity of this enzyme in

hemolysates from 25 normal subjects was 0.19±0.03 μmole glutathione formed

per g

hemoglobin per min. Glutathione synthetase also catalyzes an exchange reaction

between glycine and glutathione, but this reaction is not significant under the

conditions used for assay of hemolysates. The capacity for erythrocytes to

synthesize glutathione exceeds the rate of glutathione turnover by 150-fold,

indicating that there is considerable reserve capacity for glutathione

synthesis. A patient with erythrocyte glutathione synthetase deficiency has

been

described. The inability of patients' extracts to synthesize glutathione is

corrected by the addition of pure glutathione synthetase, indicating that there

is

no inhibitor in the patients' erythrocytes.

_[xii]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref12)

Braverman, E.R. (with Pfeiffer, C.C.)(1987). The healing nutrients within:

Facts, findings and new research on amino acids. New Canaan: Keats Publishing

_[xiii]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref13)

_http://www.dorway.org/blayautism.txt_ (http://www.dorway.org/blayautism.txt)

_[xiv]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref14)

Anghileri, L.J. Magnesium concentration variations during carcinogenesis.

Magnesium Bull. 1979; 1:46-48.

_[xv]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref15)

Anghileri, L.J., Collery, P., Coudoux, P., Durlach, J. (Experimental

relationships between magnesium and cancer.) Magnesium Bull. 1981; 3:1-5

_[xvi]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref16)

Anghileri, L.J., Heidbreder, M., Weiler, G., Dermietzel, R.

Hepatocarcinogenesis by thioacetamide: correlations of histological and

biochemical changes,

and possible role of cell injury. Exp. Cell. Biol. 1977; 45:34-47.

_[xvii]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref17)

Blondell, J.W. The anticancer effect of magnesium. Medical Hypothesis 1980;

6:863-871.

_[xviii]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref18)

Whitney, R.B., Sutherland, R.M. The influence of calcium, magnesium and

cyclic adenosine 3'5'-monophosphate on the mixed lymphocyte reaction. J.

Immunol.

1972; 108:1179-1183.

_[xix]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref19)

Petitou, M., Tuy, F., Rosenfeld, C., Mishal, Z., Paintrand, M., Jasmin, C.,

Mathe, G., Inbar, M. Decreased microviscosity of membrane lipids in leukemic

cells; two possible mechanisms. Proc. Natl. Acad. Sci. USA 1978; 75:2306-2310.

_[xx]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref20)

Hass, G.M., McCreary, P.A., Laing, G.H., Galt, R.M. Lymphoproliferative and

immumunologic aspects of magnesium deficiency. In Magnesium in Health and

Disease (from 2nd Intl Mg Sympos, Montreal, Canada, 1976), b Eds. M. Cantin,

M.S.

Seelig, Publ. Spectrum Press, NY, 1980, pp 185-200

_[xxi]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref21)

Collery, P., Anghileri, L.J., Coudoux, P., Durlach, J. (Magnesium and cancer:

Clinical data.) Magnesium Bull. 1981; 3:11-20.

_[xxii]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref22)

American Journal of Epidemiology (Vol. 163, pp. 232-235)

_[xxiii]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref23)

Journal of the American Medical Association, Vol. 293, pp. 86-89

_[xxiv]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref24)

Paunier, L., Radde, I.C.: Normal and abnormal magnesium metabolism. Bull. of

Hosp. for Sick Childr. (Toronto) 1965; 14:16-23.

_[xxv]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref25)

MAY 19, 1931, Dr. P. Schrumpf-Pierron presented a paper entitled " On the Cause

Of the Rarity of Cancer in Egypt, " which was printed in the Bulletin of the

Academy of Medicine, and the Bulletin of the French Association for the Study

of Cancer in July, 1931. http://www.mgwater.com/rod02.shtml

_[xxvi]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref26)

Yang CY et al. Jpn J Cancer Res.1998 Feb;89 (2):124-30. Calcium, magnesium,

and nitrate in drinking water and gastric cancer mortality.

_[xxvii]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref27)

New York State Department of Health;

_http://www.health.state.ny.us/diseases/conditions/osteoporosis/qanda.htm_

(http://www.health.state.ny.us/diseases/conditions/osteoporosis/qanda.htm)

_[xxviii]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref28)

Accu-Cell Nutrition; Calcium and Magnesium

_http://www.acu-cell.com/acn.html_ (http://www.acu-cell.com/acn.html)

_[xxix]_ (http://www.magnesiumforlife.com/index_references.shtml#_ednref29)

Am J Clin Nutr. 2007 Oct;86(4):1054-1063. Calcium requirements: new

estimations for men and women by cross-sectional statistical analyses of

calcium

balance data from metabolic studies.Hunt CD, Johnson LK. US Department of

Agriculture, Agricultural Research Service, Grand Forks Human Nutrition

Research

Center, Grand Forks, ND.