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Food for Chickens, Poison for Man

_http://scienceline.org/2006/09/20/env-wenner-arsenic/_

(http://scienceline.org/2006/09/20/env-wenner-arsenic/)

 

A widespread farming practice is adding arsenic to the food chain.

 

By Melinda Wenner, posted September 20th, 2006.

 

When Gwen Cox raised broiler chickens for Pilgrim’s Pride from 2001 to 2004,

she had to use poultry feed provided by the company. After a few incidents

when she felt physically ill working with it—“I would start coughing and

could hardly stop, or I’d get lightheaded or nauseous,†she remembers—she

checked the feed labels and noticed that they listed roxarsone, an organic

arsenic

compound, as an ingredient. Concerned about her chickens as well as her own

health, she asked Pilgrim’s Pride why she was being forced to use feed

containing arsenic.

 

“I was told to mind my own business,†she says. “[They told me] ‘it’s

a

microbe inhibitor and is proven to be safe in the quantity used in the feed.’

But you know some of this stuff is bad when the tickets instruct you not to

feed it to any other animals due to it being proven fatal if ingested.â€

 

Pilgrim’s Pride, the second largest chicken company in the country, wasn’t

doing anything uncommon: over 70 percent of all broiler chickens grown in the

U.S. are fed roxarsone, according to a 2000 article published in the journal

Poultry Science. Roxarsone prevents the growth of microscopic intestinal

parasites called coccidia that frequently infect livestock, and it provides the

added bonus of better growth—i.e., bigger chickens. (Despite repeated

requests, Pilgrim’s Pride would not confirm whether it still uses roxarsone.)

 

Roxarsone doesn’t disappear once chickens eat it. Some is distributed

throughout the animal’s tissues, including the breasts, thighs and

legs—meat that

is later eaten by consumers. The rest is excreted unchanged in poultry waste.

Ninety percent of this manure is later converted into fertilizer that can

contaminate crops, lakes, rivers, and eventually drinking water.

 

Little research, however, has investigated the public health consequences of

this practice, which was banned in the European Union in 1999. Although

several studies have looked at the levels of arsenic present in chicken muscle

meat, and some have looked at crop soil contamination, the results have been

inconsistent. None have determined how extensively this practice contaminates

drinking water.

 

“There’s been such a huge degree of regulatory attention paid to arsenic in

drinking water, and yet here’s this very widespread practice that has a real

potential of adding to drinking water contamination and yet nobody’s looking

at it,†says Dr. David Wallinga, director of the Food and Health Program at

the Institute for Agriculture and Trade Policy (IATP), a non-profit research

and advocacy organization based in Minneapolis.

 

Any increase in Americans’ levels of arsenic exposure is of great concern:

The Environmental Protection Agency, which regulates drinking water, considers

arsenic a class A carcinogen, meaning that data have definitively shown it

to cause cancer. Other health effects from chronic low-level exposure include

partial paralysis, blindness and diabetes. Although the EPA tightened its

regulations for arsenic levels in drinking water this past January, lowering it

from a maximum of 50 parts per billion (ppb) to 10 ppb, this new level still

exceeds the agency’s recommendations for exposure to a carcinogen by a factor

of 50.

 

The EPA typically recommends that the amount of a carcinogen in drinking

water should not cause more than one person in 100,000 to develop cancer as a

result of drinking that water daily. But Americans who are regularly drinking

water containing 10 ppb of arsenic are at a 50-fold higher cancer risk than

this: in other words, one out of every 2,000 of those Americans is likely to

develop cancer because of the arsenic in their tap water. And the EPA estimates

that 12 million Americans are currently drinking water containing more than

10 ppb of arsenic—making their cancer risk even higher.

 

The EPA isn’t meeting its own safety standard for arsenic because the

recommended amounts “are set at a level which water systems cannot meet,â€

according to agency press officer Dale Kemery. After preparing a cost / benefit

analysis, the EPA set its arsenic limits at a level that maximized risk

reduction

while minimizing cost to the consumer, he says.

 

Where is all of this arsenic coming from? Most arsenic contamination arises

from natural sources or from its former use in pesticides and wood

preservatives. Though these uses have since been banned, the arsenic remains in

the

environment and is extremely difficult to remove. The poultry industry’s use

of

roxarsone, however, is one of the few easily preventable ways in which

arsenic enters the food chain.

 

Given that arsenic is already a significant health risk, many think that its

use in poultry feed should be investigated and, if found to be a significant

source of contamination, banned.

 

This debate isn’t so cut and dried, however, because arsenic exists in both

organic and inorganic forms, and experts disagree about the relative toxicity

of the two.

 

According to the FDA, which monitors the use of drugs in animal feed,

organic forms of arsenic like roxarsone, which are bound to carbon and

hydrogen,

are “not considered to be carcinogens and are considerably less toxic than

inorganic forms of arsenic,†writes agency spokesperson Michael Herndon in an

e-mail.

 

But the Agency for Toxic Substances and Disease Registry, part of the U.S.

Department of Health and Human Services, states that “almost no information

is

available on the effects of organic arsenic compounds in humans.†ATSDR also

says that high doses of organic arsenic can produce some of the same effects

as inorganic forms.

 

And although roxarsone starts as an organic molecule, it doesn’t stay that

way. When a chicken eats feed containing roxarsone, most of it—about 150

milligrams over a chicken’s lifetime—is excreted unchanged in the

chicken’s

waste. After 30 days, the excreted roxarsone naturally converts into other

forms

of arsenic, including highly toxic inorganic forms like arsenite, according to

a study published this year in Environmental Science & Technology.

 

Inorganic forms of arsenic, which are bound to oxygen, chlorine or sulfur,

are therefore present in poultry manure. “This waste is then spread on fields

near poultry farms,†writes Ellen Silbergeld, a professor of environmental

health sciences at Johns Hopkins University, in an e-mail. “The poultry

industry is processing and selling poultry waste as garden fertilizer for

consumers

to use in home gardens and lawns.â€

 

According to chemist John Garbarino, a co-author of the study in

Environmental Science & Technology, the arsenite present in manure and

fertilizer binds

poorly to soil particles, making it highly mobile in the environment such

that it can easily contaminate nearby lakes and streams. Arsenite “is

considered

to be one of the more toxic arsenic species,†he writes in an e-mail.

 

Roxarsone meets the FDA’s criteria for approval because it has been shown to

be safe for chickens. The compound also meets the guidelines of the USDA,

the agency that monitors food safety, because roxarsone residues in chicken

tissue don’t exceed the agency’s safety levels. However, roxarsone’s

potential

downstream effects are not being addressed by either agency. And the agency

responsible for regulating roxarsone’s byproducts in drinking water—the

EPA—

has no jurisdiction over roxarsone’s use in chicken feed.

 

Richard Lobb, director of communications for the National Chicken Council—a

non-profit organization representing poultry producers and distributors—

argues that toxic forms of arsenic occur naturally in the environment and that

the

additional levels from the use of arsenic in poultry feed “are just so

smallâ€

that they are most likely not a problem.

 

“Arsenic is just there, it is elemental, it is in the rock in many, many

areas and it just occurs naturally,†he says.

 

The amount of arsenic released into the environment via poultry manure is

approximately 250 to 350 metric tons per year, according to several recent

peer-reviewed studies. This can be compared to natural releases of arsenic,

mostly from volcanoes, which the EPA estimates are in the range of 2,800 to

8,000

metric tons per year. There are also other ways that arsenic gets into the

environment, including metal smelting and coal burning, but the exact amount

released from these other sources is unclear.

 

How much of the “extra†arsenic entering the environment via feed is

contaminating drinking water? No one seems to know for sure. “We do not know

enough

about this,†writes Silbergeld in an e-mail. “In some parts of the U.S.,

naturally occurring sources of arsenic [like those found in rocks] are a very

important source of arsenic in ground water. In other areas, disposal of

poultry waste may be the most important.â€

 

According to Brian Fairchild, a poultry scientist at the University of

Georgia, the best way to clearly determine roxarsone’s downstream effects is

to

improve the technology used in the research. While some studies have been

published on roxarsone’s effects on soil, “there’s no consistent data,â€

he says.

If the scientists studying it today “are using the same old techniques that

have been used for the past 10 years, I don’t think we’re going to get any

closer to the answer than we were five years ago.â€

 

Lobb agrees that more—and better—studies would be helpful. “I think this

area really cries out for some more objective research, and I hope somebody

will supply that one of these days,†he says. “But the reason that no one

is

doing it, I guess, is because there does not seem to be a problem here.â€

 

In addition to potentially contaminating drinking water, some of the arsenic

ingested by a chicken remains in its liver and muscle tissue—and is later

eaten by consumers. A study led by Wallinga at the IATP, which was not reviewed

by independent experts, found that of 155 chicken products bought from

Minnesota and California supermarkets in 2004 and 2005, more than half contained

detectable levels of arsenic. An earlier study by the USDA found that on

average, people eat from 1.4 to 5.24 micrograms of inorganic arsenic each day

from

chicken alone.

 

That amount again exceeds the EPA’s recommended daily levels for arsenic

exposure. In order to have a lifetime cancer risk of less than one in 100,000,

a

person of average weight would need to ingest less than 0.469 micrograms of

arsenic per day. Exposure to arsenic from eating chicken alone therefore is

between three and 11 times the recommended safety level.

 

The USDA, however, has set its limits much higher, and the amount of arsenic

in the chicken tested by the IATP does not exceed them. The USDA’s limit for

arsenic in poultry breasts is 500 ppb; the highest level of arsenic found by

the IATP study was 21.2 ppb in some Purdue boneless breasts. But the USDA

does not regularly test chicken breasts, thighs or legs to ensure that they

conform to these standards. It only tests chicken livers because arsenic is

known to concentrate there.

 

Levels of arsenic also seem to vary consistently across chicken suppliers,

so consumers can control the amount of arsenic they get from their chicken, at

least to some degree. For instance, the IATP’s study found that Tyson

chicken consistently tested low for arsenic, whereas Purdue was consistently at

the

high end. Organic chicken, which according to organic farming statutes

cannot be fed roxarsone, also had low arsenic levels.

 

Lobb, from the National Chicken Council, argues that the IATP’s study had

serious flaws because it did not control for the other ways in which the

chickens could have been exposed to arsenic. “The water supply for the

chicken

house is typically well water,†he says. “So if you happen to have

arsenic-containing rock that underlies the chicken production area, then

they’re going to

be getting it just through their water.â€

 

Wallinga agrees that the study wasn’t designed as well as it could have

been. He also wishes he could have tested more samples. But “It shouldn’t

be up

to Dr. David Wallinga to be monitoring the U.S. food supply for arsenic,†he

says. “It should be up to the FDA. And if they’re not looking, they can’t

answer these questions.â€

 

These days, Gwen Cox is no longer contract farming for Pilgrim’s Pride—and

she’s much happier for it. She still raises a dozen “pet†chickens and

about

two dozen cattle, but she insists on doing so without roxarsone. She has had

no coccidia outbreaks, though she admits that backyard flocks like her own

are much less susceptible to disease than contracted poultry raised in close

quarters.

 

“When a bird can do as it wants, eat what it wants and have plenty of clean,

fresh air as well as pure water and untainted feed, you’d be surprised how

healthy and disease-free they remain,†she says.

 

Cox and her friend Katherine Ecker, who owns Legacy Manor, a free-range farm

in Boonsboro, Maryland, blame coccidia outbreaks partially on stress and

lack of space. “Chickens in the broiler houses by nature have a tendency to

pick

at the ground,†Ecker explains. In contract farms, the chickens are in very

close quarters, and since coccidia are spread by manure, the chickens have a

much higher chance of getting sick.

 

Ecker admits that she does occasionally have a coccidia outbreak, but when

it occurs, she never uses roxarsone. She finds that amprolium, a compound that

is significantly less toxic to humans, works as a comparable alternative.

 

The pharmaceutical company Schering-Plough has also recently developed

several coccidia vaccines for chicks; Embrex, another company, has a new in ovo

coccidia vaccine that is injected into the egg before the chick hatches. These

vaccines may prevent coccidiosis from occurring in the first place.

 

With low-risk treatments readily available, why is roxarsone being used—and

why is it still legal? Silbergeld of Johns Hopkins blames the FDA’s apparent

reluctance to ban roxarsone on the influence of industry. “The major ‘

pressure’ to keep drugs in animal feeds comes from the pharmaceutical

industry,

since over 60 percent of antibiotic production, and 100 percent of roxarsone

production, is used for nonclinical ‘growth promoting’ purposes in

animals,â€

she writes in an e-mail.

 

Wallinga points more of the blame directly at the regulatory agencies. They

have not looked into the issue sufficiently, he says, so they have no reason

to believe there is a problem.

 

Agency spokesperson Herndon, however, contends that the FDA is “continuing

to track the environmental monitoring data being generated by EPA, United

States Geological Service and others.â€

 

But because farmers like Cox and Ecker—not to mention all European growers—

successfully raise poultry without roxarsone, Wallinga sees no rational

reason for the practice to continue until agencies can be sure that the

practice

is safe.

 

“Clearly it’s possible to produce chicken with no or little arsenic,†he

says. “So why are all these other people still using it?â€

 

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