Ingredients of FAHF-1 (Antiallergic formula)

[Guest guest]

Hi Alex, & All,

 

Alex Berk wrote:

> ...Herbal formula silences peanut allergy in mice ... What is in this

> formula? In looking around pubmed I found the difference between FAHF-1

> and FAHF-2 is the removal of xixin and fuzi but there is no listing

> of the herbs. Does anyone know what it is?

 

http://tinyurl.com/qxfmj says:

Herbs that fight nut allergy disclosed, By Terry Murray

 

NEW YORK ¨C The formula has been revealed, 12 months later¡ªthe

names of 11 Chinese herbs reported at the AAAAI meeting last year to

have a striking effect on peanut allergy in a mouse model.

 

Dr. Xiu-Min Li, assistant professor of pediatrics and clinical immunology

at the Mount Sinai School of Medicine here, told the conference last

year that the herbal formula reduced peanut-specific IgE levels in the

mice by more than 30% and protected the animals from anaphylaxis.

However, neither she nor another investigator on the project would

reveal the contents of the formulation (see Medical Post, April 17,

2001).

 

But in a seminar on alternative therapies in food allergy at this year's

conference, Dr. Li named the contents. She listed the components of

FAHF-1 (or food allergy herbal formula 1) first by their traditional

Chinese medicine designation (in Pinyin), followed by the equivalent

pharmaceutical name:

 

Lingzhi (Chi), or Ganoderma lucidum;

Fuzi (zhi), or Radix lateralis aconiti carmicaeli praeparata;

Wumei, or Fructus pruni mume;

Chuanjiao, or Pericarpium zanthoxyli bungeani;

Xixin, or Herba cum radice asari;

Huanglian (Chuan), or Rhizoma coptidis;

Huangbai, or Cortex phellodendri;

Ganjiang, or Rhizoma zingiberis officinalis;

Guizhi, or Ramulus cinnamomi cassiae;

Renshen (Hong), or Radix ginseng; and

Danggui (shen), or Corpus radix angelicae sinensis.

 

The Mt. Sinai researchers are working to standardize FAHF-1, to

explore the way in which it suppresses allergic reactions and to

determine the best combination of the 11 ingredients, Dr. Li said.

They have also moved " one step closer to clinical study " by starting to

evaluate FAHF-1 with human mucosal lymphocytes from four milk-

allergic patients, she added. But she said only that in cell culture, FAHF-

1 produced a " clear reduction " in proliferation and in IL-4 and IL-13, but

did not alter interferon-gamma production.

 

The ingredients, above, refer to FAHF-1. The version used in the US

trial (FAHF-2) removed Xixin & Fuzi, but that removel did not reduce the

anti-allergic effect.

http://nccam.nih.gov/news/newsletter/2006_winter/roundup.htm

 

Best regards,

Phil

[Guest guest]

hi phil & alex...

 

i did some research on this a while back...

took me a while to figure this to be wu mei wan + ling zhi...

[there's only so many formulae with wu mei in them ;-P]

 

i didn't get much of a grasp as to why this would treat anaphylaxis

[albeit in mice] but thought its ability to treat hot and cold was

interesting...

wu mei wan, as i know it, has been used to treat roundworms and long

term diarrhoea - hot or cold can depend on modifications...

 

seems like the modification of dropping fu zi and xi xin makes the

formula more targeted at treating heat conditions...

in terms of excessive immune response or excessive inflammatory

response anaphylaxis could be considered a heat condition..

 

huang lian & huang bai could be major players [i think huang qin

could be a helpful modification to add to this effect]

 

i thought wu mei's sour taste [astringency] must be a factor...

[perhaps affecting the immune response or digestive tract/immune

response interaction?]

 

in the article it specified both wu mei and ling zhi made up 28% of

the formula each [56% together] - so i figured their actions were

probably paramount....

 

i had a friend researching at a hospital to get me the paper:

" The Chinese herbal medicine formula FAHF-2 completely blocks

anaphylactic reactions in a murine model of peanut allergy "

from the Journal Allergy Clinical Immunology VOLUME 115,NUMBER 1 -

jan 2005

 

i can post a .pdf copy if anyone would like it

 

i was researching for treatment of a young boy with a severe peanut

allergy, but as yet haven't begun any herbal treatment...

 

 

:-)

brendon

 

 

 

 

 

, " "

< wrote:

>

> Hi Alex, & All,

>

> Alex Berk wrote:

> > ...Herbal formula silences peanut allergy in mice ... What is in

this

> > formula? In looking around pubmed I found the difference between

FAHF-1

> > and FAHF-2 is the removal of xixin and fuzi but there is no

listing

> > of the herbs. Does anyone know what it is?

>

> http://tinyurl.com/qxfmj says:

> Herbs that fight nut allergy disclosed, By Terry Murray

>

> NEW YORK ¨C The formula has been revealed, 12 months later¡ªthe

> names of 11 Chinese herbs reported at the AAAAI meeting last year

to

> have a striking effect on peanut allergy in a mouse model.

>

> Dr. Xiu-Min Li, assistant professor of pediatrics and clinical

immunology

> at the Mount Sinai School of Medicine here, told the conference

last

> year that the herbal formula reduced peanut-specific IgE levels in

the

> mice by more than 30% and protected the animals from anaphylaxis.

> However, neither she nor another investigator on the project would

> reveal the contents of the formulation (see Medical Post, April 17,

> 2001).

>

> But in a seminar on alternative therapies in food allergy at this

year's

> conference, Dr. Li named the contents. She listed the components of

> FAHF-1 (or food allergy herbal formula 1) first by their

traditional

> Chinese medicine designation (in Pinyin), followed by the

equivalent

> pharmaceutical name:

>

> Lingzhi (Chi), or Ganoderma lucidum;

> Fuzi (zhi), or Radix lateralis aconiti carmicaeli praeparata;

> Wumei, or Fructus pruni mume;

> Chuanjiao, or Pericarpium zanthoxyli bungeani;

> Xixin, or Herba cum radice asari;

> Huanglian (Chuan), or Rhizoma coptidis;

> Huangbai, or Cortex phellodendri;

> Ganjiang, or Rhizoma zingiberis officinalis;

> Guizhi, or Ramulus cinnamomi cassiae;

> Renshen (Hong), or Radix ginseng; and

> Danggui (shen), or Corpus radix angelicae sinensis.

>

> The Mt. Sinai researchers are working to standardize FAHF-1, to

> explore the way in which it suppresses allergic reactions and to

> determine the best combination of the 11 ingredients, Dr. Li said.

> They have also moved " one step closer to clinical study " by

starting to

> evaluate FAHF-1 with human mucosal lymphocytes from four milk-

> allergic patients, she added. But she said only that in cell

culture, FAHF-

> 1 produced a " clear reduction " in proliferation and in IL-4 and IL-

13, but

> did not alter interferon-gamma production.

>

> The ingredients, above, refer to FAHF-1. The version used in the US

> trial (FAHF-2) removed Xixin & Fuzi, but that removel did not

reduce the

> anti-allergic effect.

> http://nccam.nih.gov/news/newsletter/2006_winter/roundup.htm

>

> Best regards,

> Phil

>

[Guest guest]

I thought ku shen was a major part of the formulas this group used for allergies

 

 

 

 

Oakland, CA 94609

 

 

-

dkssud6_6

Saturday, April 29, 2006 2:33 AM

Re: Ingredients of FAHF-1 (Antiallergic formula)

 

 

hi phil & alex...

 

i did some research on this a while back...

took me a while to figure this to be wu mei wan + ling zhi...

[there's only so many formulae with wu mei in them ;-P]

 

i didn't get much of a grasp as to why this would treat anaphylaxis

[albeit in mice] but thought its ability to treat hot and cold was

interesting...

wu mei wan, as i know it, has been used to treat roundworms and long

term diarrhoea - hot or cold can depend on modifications...

 

seems like the modification of dropping fu zi and xi xin makes the

formula more targeted at treating heat conditions...

in terms of excessive immune response or excessive inflammatory

response anaphylaxis could be considered a heat condition..

 

huang lian & huang bai could be major players [i think huang qin

could be a helpful modification to add to this effect]

 

i thought wu mei's sour taste [astringency] must be a factor...

[perhaps affecting the immune response or digestive tract/immune

response interaction?]

 

in the article it specified both wu mei and ling zhi made up 28% of

the formula each [56% together] - so i figured their actions were

probably paramount....

 

i had a friend researching at a hospital to get me the paper:

" The Chinese herbal medicine formula FAHF-2 completely blocks

anaphylactic reactions in a murine model of peanut allergy "

from the Journal Allergy Clinical Immunology VOLUME 115,NUMBER 1 -

jan 2005

 

i can post a .pdf copy if anyone would like it

 

i was researching for treatment of a young boy with a severe peanut

allergy, but as yet haven't begun any herbal treatment...

 

 

:-)

brendon

 

 

 

 

 

, " "

< wrote:

>

> Hi Alex, & All,

>

> Alex Berk wrote:

> > ...Herbal formula silences peanut allergy in mice ... What is in

this

> > formula? In looking around pubmed I found the difference between

FAHF-1

> > and FAHF-2 is the removal of xixin and fuzi but there is no

listing

> > of the herbs. Does anyone know what it is?

>

> http://tinyurl.com/qxfmj says:

> Herbs that fight nut allergy disclosed, By Terry Murray

>

> NEW YORK ¨C The formula has been revealed, 12 months later¡ªthe

> names of 11 Chinese herbs reported at the AAAAI meeting last year

to

> have a striking effect on peanut allergy in a mouse model.

>

> Dr. Xiu-Min Li, assistant professor of pediatrics and clinical

immunology

> at the Mount Sinai School of Medicine here, told the conference

last

> year that the herbal formula reduced peanut-specific IgE levels in

the

> mice by more than 30% and protected the animals from anaphylaxis.

> However, neither she nor another investigator on the project would

> reveal the contents of the formulation (see Medical Post, April 17,

> 2001).

>

> But in a seminar on alternative therapies in food allergy at this

year's

> conference, Dr. Li named the contents. She listed the components of

> FAHF-1 (or food allergy herbal formula 1) first by their

traditional

> Chinese medicine designation (in Pinyin), followed by the

equivalent

> pharmaceutical name:

>

> Lingzhi (Chi), or Ganoderma lucidum;

> Fuzi (zhi), or Radix lateralis aconiti carmicaeli praeparata;

> Wumei, or Fructus pruni mume;

> Chuanjiao, or Pericarpium zanthoxyli bungeani;

> Xixin, or Herba cum radice asari;

> Huanglian (Chuan), or Rhizoma coptidis;

> Huangbai, or Cortex phellodendri;

> Ganjiang, or Rhizoma zingiberis officinalis;

> Guizhi, or Ramulus cinnamomi cassiae;

> Renshen (Hong), or Radix ginseng; and

> Danggui (shen), or Corpus radix angelicae sinensis.

>

> The Mt. Sinai researchers are working to standardize FAHF-1, to

> explore the way in which it suppresses allergic reactions and to

> determine the best combination of the 11 ingredients, Dr. Li said.

> They have also moved " one step closer to clinical study " by

starting to

> evaluate FAHF-1 with human mucosal lymphocytes from four milk-

> allergic patients, she added. But she said only that in cell

culture, FAHF-

> 1 produced a " clear reduction " in proliferation and in IL-4 and IL-

13, but

> did not alter interferon-gamma production.

>

> The ingredients, above, refer to FAHF-1. The version used in the US

> trial (FAHF-2) removed Xixin & Fuzi, but that removel did not

reduce the

> anti-allergic effect.

> http://nccam.nih.gov/news/newsletter/2006_winter/roundup.htm

>

> Best regards,

> Phil

>

 

 

 

 

 

 

 

 

 

Chinese Herbal Medicine offers various professional services, including board

approved continuing education classes, an annual conference and a free

discussion forum in Chinese Herbal Medicine.

 

 

 

 

 

[Guest guest]

from what i found out, there were a different set of formula that

used ku shen, huang qin and ling zhi...

i'll find a quote...

 

here it is:

 

Other particularly preferred inventive herbal compositions include at

least the herbs Huang Qing, Ku Sen, and Ling Zhi. In certain

preferred embodiments, these herbs are present in relative amounts

approximating 3:3:2 ratios. Alternatively or additionally, preferred

compositions may include one or more of Dong Gui and Ge Gen. Relative

amounts of these herbs, in certain particularly preferred

compositions, will approximate the levels of Huang Qing and/or Ku

Sen. Other preferred embodiments may further, or alternatively,

include Su Zi, preferably at a level approximating that of Huang Qing

and/or Ku Sen. One particularly preferred inventive herbal

formulation is MSSM-002 (see Table 3 and FIG. 13).

TABLE 3

MSSM-02 FORMULATION

CHINESE NAME PLANT NAME AMOUNT

Su Zi Perillae frutescens 9 g

Ting li zi Descurainia sophia 9 g

Xing reni Prunus armeniaca 9 g

Huang Qing Scutellaria baicalensis 9 g

Ku Shen Sophora flavescens 9 g

Dang Gui Angelica sinensis 9 g

Bai Shao Paeonia lactiflora 9 g

Ge Gen Peuraria lobata 9 g

Jie Gen Platycodon grandiflorum 6 g

Zhen Zhu Mu Pteria margaratiferae 6 g

Ling Zhi Ganoderma lucidum 6 g

Gan Cao Glycyrrhiza uralensis 6 g

Da Zao Ziziphus jujuba 5 pieces

Shen Jiang Frash Zingiber officianale 6 g

 

 

:-)

b

 

 

<alonmarcus wrote:

>

> I thought ku shen was a major part of the formulas this group used

for allergies

>

>

>

[Guest guest]

Finding your legislator.....

 

Type into your computer

 

www.ca.gov

click government

click California Legislature

click California State Assembly

click Find my district

or

click Member Directory

 

SUPPORT AB-3014

 

Contact your Assembly district representative in Sacramento

Call other Assembly members too....

Call as many members as you can between now and Wednesday/Thursday

 

Tell others how easy it is to help make a difference.

 

Let your voice be heard in Sacramento.

 

 

 

 

Oakland, CA 94609

 

 

-

dkssud6_6

Saturday, April 29, 2006 10:07 PM

Re: Ingredients of FAHF-1 (Antiallergic formula)

 

 

from what i found out, there were a different set of formula that

used ku shen, huang qin and ling zhi...

i'll find a quote...

 

here it is:

 

Other particularly preferred inventive herbal compositions include at

least the herbs Huang Qing, Ku Sen, and Ling Zhi. In certain

preferred embodiments, these herbs are present in relative amounts

approximating 3:3:2 ratios. Alternatively or additionally, preferred

compositions may include one or more of Dong Gui and Ge Gen. Relative

amounts of these herbs, in certain particularly preferred

compositions, will approximate the levels of Huang Qing and/or Ku

Sen. Other preferred embodiments may further, or alternatively,

include Su Zi, preferably at a level approximating that of Huang Qing

and/or Ku Sen. One particularly preferred inventive herbal

formulation is MSSM-002 (see Table 3 and FIG. 13).

TABLE 3

MSSM-02 FORMULATION

CHINESE NAME PLANT NAME AMOUNT

Su Zi Perillae frutescens 9 g

Ting li zi Descurainia sophia 9 g

Xing reni Prunus armeniaca 9 g

Huang Qing Scutellaria baicalensis 9 g

Ku Shen Sophora flavescens 9 g

Dang Gui Angelica sinensis 9 g

Bai Shao Paeonia lactiflora 9 g

Ge Gen Peuraria lobata 9 g

Jie Gen Platycodon grandiflorum 6 g

Zhen Zhu Mu Pteria margaratiferae 6 g

Ling Zhi Ganoderma lucidum 6 g

Gan Cao Glycyrrhiza uralensis 6 g

Da Zao Ziziphus jujuba 5 pieces

Shen Jiang Frash Zingiber officianale 6 g

 

 

:-)

b

 

 

<alonmarcus wrote:

>

> I thought ku shen was a major part of the formulas this group used

for allergies

>

>

>

 

 

 

 

 

 

 

 

 

Chinese Herbal Medicine offers various professional services, including board

approved continuing education classes, an annual conference and a free

discussion forum in Chinese Herbal Medicine.

 

 

 

 

 

[Guest guest]

Somatosensory cortical plasticity in carpal tunnel syndrome treated by

acupuncture. Hum Brain Mapp. 2006 Jun 7;. Carpal tunnel syndrome (CTS) is a

common entrapment neuropathy of the median nerve characterized by paresthesias

and pain in the first through fourth digits. We hypothesize that aberrant

afferent input from CTS will lead to maladaptive cortical plasticity, which may

be corrected by appropriate therapy. Functional MRI (fMRI) scanning and clinical

testing was performed on CTS patients at baseline and after 5 weeks of

acupuncture treatment. As a control, healthy adults were also tested 5 weeks

apart. During fMRI, sensory stimulation was performed for median nerve

innervated digit 2 (D2) and digit 3 (D3), and ulnar nerve innervated digit 5

(D5). Surface-based and region of interest (ROI)-based analyses demonstrated

that while the extent of fMRI activity in contralateral Brodmann Area 1 (BA 1)

and BA 4 was increased in CTS compared to healthy adults, after acupuncture

there was a significant decrease in contralateral BA 1 (P < 0.005) and BA 4 (P <

0.05) activity during D3 sensory stimulation. Healthy adults demonstrated no

significant test-retest differences for any digit tested. While D3/D2 separation

was contracted or blurred in CTS patients compared to healthy adults, the D2 SI

representation shifted laterally after acupuncture treatment, leading to

increased D3/D2 separation. Increasing D3/D2 separation correlated with

decreasing paresthesias in CTS patients (P < 0.05). As CTS-induced paresthesias

constitute diffuse, synchronized, multidigit symptomatology, our results for

maladaptive change and correction are consistent with Hebbian plasticity

mechanisms. Acupuncture, a somatosensory conditioning stimulus, shows promise in

inducing beneficial cortical plasticity manifested by more focused digital

representations. Hum Brain Mapp, 2006. © 2006 Wiley-Liss, Inc.

 

 

 

Oakland, CA 94609

 

 

-

dkssud6_6

Saturday, April 29, 2006 10:07 PM

Re: Ingredients of FAHF-1 (Antiallergic formula)

 

 

from what i found out, there were a different set of formula that

used ku shen, huang qin and ling zhi...

i'll find a quote...

 

here it is:

 

Other particularly preferred inventive herbal compositions include at

least the herbs Huang Qing, Ku Sen, and Ling Zhi. In certain

preferred embodiments, these herbs are present in relative amounts

approximating 3:3:2 ratios. Alternatively or additionally, preferred

compositions may include one or more of Dong Gui and Ge Gen. Relative

amounts of these herbs, in certain particularly preferred

compositions, will approximate the levels of Huang Qing and/or Ku

Sen. Other preferred embodiments may further, or alternatively,

include Su Zi, preferably at a level approximating that of Huang Qing

and/or Ku Sen. One particularly preferred inventive herbal

formulation is MSSM-002 (see Table 3 and FIG. 13).

TABLE 3

MSSM-02 FORMULATION

CHINESE NAME PLANT NAME AMOUNT

Su Zi Perillae frutescens 9 g

Ting li zi Descurainia sophia 9 g

Xing reni Prunus armeniaca 9 g

Huang Qing Scutellaria baicalensis 9 g

Ku Shen Sophora flavescens 9 g

Dang Gui Angelica sinensis 9 g

Bai Shao Paeonia lactiflora 9 g

Ge Gen Peuraria lobata 9 g

Jie Gen Platycodon grandiflorum 6 g

Zhen Zhu Mu Pteria margaratiferae 6 g

Ling Zhi Ganoderma lucidum 6 g

Gan Cao Glycyrrhiza uralensis 6 g

Da Zao Ziziphus jujuba 5 pieces

Shen Jiang Frash Zingiber officianale 6 g

 

 

:-)

b

 

 

<alonmarcus wrote:

>

> I thought ku shen was a major part of the formulas this group used

for allergies

>

>

>

 

 

 

 

 

 

 

 

 

Chinese Herbal Medicine offers various professional services, including board

approved continuing education classes, an annual conference and a free

discussion forum in Chinese Herbal Medicine.