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LLLT v Placebo LLLT in Achilles tendinitis

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Hi All,

 

Re LLLT, see this:

 

Bjordal JM, Lopes-Martins RA, Iversen VV. A randomised, placebo

controlled trial of low level laser therapy for activated Achilles tendinitis

with microdialysis measurement of peritendinous prostaglandin E2

concentrations. Br J Sports Med. 2006 Jan;40(1):76-80; discussion 76-

80. Physiotherapy Science, University of Bergen, Bergen, Norway.

jmbjor BACKGROUND: Low level laser therapy (LLLT)

has gained increasing popularity in the management of tendinopathy

and arthritis. Results from in vitro and in vivo studies have suggested

that inflammatory modulation is one of several possible biological

mechanisms of LLLT action. OBJECTIVE: To investigate in situ if LLLT

has an anti-inflammatory effect on activated tendinitis of the human

Achilles tendon. SUBJECTS: Seven patients with bilateral Achilles

tendinitis (14 tendons) who had aggravated symptoms produced by

pain inducing activity immediately before the study. METHOD: Infrared

(904 nm wavelength) LLLT (5.4 J per point, power density 20 mW/cm2)

and placebo LLLT (0 J) were administered to both Achilles tendons in

random blinded order. RESULTS: Ultrasonography Doppler

measurements at baseline showed minor inflammation through

increased intratendinous blood flow in all 14 tendons and measurable

resistive index in eight tendons of 0.91 (95% confidence interval 0.87 to

0.95). Prostaglandin E2 concentrations were significantly reduced 75,

90, and 105 minutes after active LLLT compared with concentrations

before treatment (p = 0.026) and after placebo LLLT (p = 0.009).

Pressure pain threshold had increased significantly (p = 0.012) after

active LLLT compared with placebo LLLT: the mean difference in the

change between the groups was 0.40 kg/cm2 (95% confidence interval

0.10 to 0.70). CONCLUSION: LLLT at a dose of 5.4 J/point can reduce

inflammation and pain in activated Achilles tendinitis. LLLT may

therefore have potential in the management of diseases with an

inflammatory component. PMID: 16371497 [PubMed - in process]

 

NOTE the relatively high dose used (5.4 J/point and power density 20

mW/cm2)

 

 

Best regards,

 

 

Tel: (H): +353-(0) or (M): +353-(0)

 

 

 

 

Ireland.

Tel: (W): +353-(0) or (M): +353-(0)

 

 

 

" Man who says it can't be done should not interrupt man doing it " -

Chinese Proverb

 

 

 

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Dear All , Phil

 

Please note this is Low level laser therapy where laser is not applied to

acupuncture point. So influencing acupuncture point has a very less chance.

That is probably why higher dosage is needed. This may show the pure effect

of low level laser on the tissue irradiated. And it can clearly demonstrate

that acupuncture laser may have a totally different mode of action than

laser application to non acupoints.

 

 

 

Regards,

Dr, Fadaie

 

 

> " " <

>Chinese Medicine

>pa-l , PVA-L ,

>traditional_Chinese_Medicine

> LLLT v Placebo LLLT in Achilles tendinitis

>Sat, 31 Dec 2005 16:32:57 -0000

>

>Hi All,

>

>Re LLLT, see this:

>

>Bjordal JM, Lopes-Martins RA, Iversen VV. A randomised, placebo

>controlled trial of low level laser therapy for activated Achilles

>tendinitis

>with microdialysis measurement of peritendinous prostaglandin E2

>concentrations. Br J Sports Med. 2006 Jan;40(1):76-80; discussion 76-

>80. Physiotherapy Science, University of Bergen, Bergen, Norway.

>jmbjor BACKGROUND: Low level laser therapy (LLLT)

>has gained increasing popularity in the management of tendinopathy

>and arthritis. Results from in vitro and in vivo studies have suggested

>that inflammatory modulation is one of several possible biological

>mechanisms of LLLT action. OBJECTIVE: To investigate in situ if LLLT

>has an anti-inflammatory effect on activated tendinitis of the human

>Achilles tendon. SUBJECTS: Seven patients with bilateral Achilles

>tendinitis (14 tendons) who had aggravated symptoms produced by

>pain inducing activity immediately before the study. METHOD: Infrared

>(904 nm wavelength) LLLT (5.4 J per point, power density 20 mW/cm2)

>and placebo LLLT (0 J) were administered to both Achilles tendons in

>random blinded order. RESULTS: Ultrasonography Doppler

>measurements at baseline showed minor inflammation through

>increased intratendinous blood flow in all 14 tendons and measurable

>resistive index in eight tendons of 0.91 (95% confidence interval 0.87 to

>0.95). Prostaglandin E2 concentrations were significantly reduced 75,

>90, and 105 minutes after active LLLT compared with concentrations

>before treatment (p = 0.026) and after placebo LLLT (p = 0.009).

>Pressure pain threshold had increased significantly (p = 0.012) after

>active LLLT compared with placebo LLLT: the mean difference in the

>change between the groups was 0.40 kg/cm2 (95% confidence interval

>0.10 to 0.70). CONCLUSION: LLLT at a dose of 5.4 J/point can reduce

>inflammation and pain in activated Achilles tendinitis. LLLT may

>therefore have potential in the management of diseases with an

>inflammatory component. PMID: 16371497 [PubMed - in process]

>

>NOTE the relatively high dose used (5.4 J/point and power density 20

>mW/cm2)

>

>

>Best regards,

>

>

>Tel: (H): +353-(0) or (M): +353-(0)

>

>

>

>

>Ireland.

>Tel: (W): +353-(0) or (M): +353-(0)

>

>

>

> " Man who says it can't be done should not interrupt man doing it " -

>Chinese Proverb

>

>

>

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