Tofu mends broken bones and teeth

[Guest guest]

Hi all,

 

Taken from: http://news.bbc.co.uk/1/hi/health/4057631.stm

 

A material made from the vegetarian food tofu could help repair

broken bones and teeth, UK scientists believe.

The de-fatted soybean curd would act like polyfiller to fill in

defects.

 

It has the added advantage of encouraging new bone to grow as it

biodegrades and releases natural anti-inflammatory agents.

 

Inventor Dr Matteo Santin of Brighton University has teamed up with

experts from the University of Naples and WessexBio to develop the

material.

 

Bone filler

 

Many existing materials used to fill bone are derived from animal

sources, which the patient's immune system can react to and reject

as foreign material.

 

Dr Santin believes using the vegetable-based product should avoid

this problem.

 

" The innovation is that it accelerates the growth of the patient's

own bone, rather than using an artificial substitute which the body

could react against.

 

" Crucially, it also combats inflammation, " he said.

 

He is hopeful that the tofu-based material would give dental

implants a greater chance of success.

 

Dental implants are specially made posts that replace the roots of

teeth that are missing to support a new crown, fixed bridge or

denture.

 

In some cases the implant fails because it does not integrate with

the jaw bone.

 

Teeth too

 

Dr Santin said: " It will be suitable for anyone who has lost a

tooth, making implants available to many more people.

 

" We're keen to develop a gel or a paste which dentists will be able

to use in any mouth, irrespective of the severity of the bone

defect. "

 

Dr Jonathan Wilkinson from WessexBio explained that some gaps in

bone were too big for the body to bridge itself.

 

" This works like a scaffold and whilst it biodegrades the bone

regrows into the scaffold. "

 

He said, in the future, it could be used by orthopaedic surgeons and

by surgeons doing complicated face reconstruction surgery.

 

" The third application is for use in wound healing. There is very

good evidence that is would work well. "

 

So far the researchers have tested the material in the laboratory.

 

With new funding from the National Endowment for Science, Technology

and the Arts (NESTA), they hope to be able to test it in clinical

settings.

 

Attilio