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Rachel's #939: NIGHT WORK , BREAST AND PROSTATE CANCER

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At 05:12 PM 12/29/07, you wrote:

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>Physician's First watch, Nov. 30, 2007

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>

>INTERNATIONAL AGENCY PLANS TO CALL NIGHT WORK A PROBABLE CARCINOGEN

>

>The International Agency for Research on Cancer plans to categorize

>overnight shift work as a probable carcinogen, according to the

>Associated Press.

>

>The AP says the agency will make the change in December, and the

>American Cancer Society is likely to follow suit. Until now, the ACS

>has considered the association between cancer and night work to be

> " uncertain, controversial or unproven. "

>

>Several epidemiologic studies, done mostly on nurses and flight crews,

>have shown a link between night work and cancer of the breast and

>prostate, the AP notes. Another analysis, prepared by the IARC, will

>be published in the December issue of Lancet Oncology.

>

>In theory, sleep loss and circadian disruptions resulting from night

>work could contribute to cancer risk. Being exposed to light at night

>could disrupt production of melatonin, a hormone that can limit tumor

>growth.

>

>Associated Press story (Free)

>

>American Journal of Epidemiology article on rotating shift work and

>prostate cancer, 2006 (Free)

>

>Related Journal Watch link(s):

>

>Journal Watch General Medicine summary of studies on night shift work

>and breast cancer, 2001 (Free)

 

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