Guest guest Posted October 15, 2007 Report Share Posted October 15, 2007 Calcium and vitamin D linked to cutting fractures By Alex McNally 24/08/2007 - A new meta-analysis on calcium and vitamin D supplementation in cutting osteoporotic fractures in people aged over 50 could quell concerns over conflicting outcomes of previous studies. Researchers writing in this week's The Lancet identified 29 randomised trials featuring 63, 897 people over the age of 50, and found that where people were sticking to a prescribed dose of the two, fraction risk was reduced. The combination of vitamin D and calcium has long been recommended to reduce the risk of bone fracture for older people, and this study adds to that ever increasing body of evidence, particularly those at risk of or suffering from osteoporosis, which is estimated to affect about 75m people in Europe, USA and Japan....... .......The teams' meta-analysis found that treatment effect in individuals was better with calcium doses of 1200 mg or more, than with doses less than 1200 mg, and with vitamin D doses of 800 IU or more, than with doses less than 800 IU. Lead author Dr Benjamin Tang, from the University of Sydney in Australia, said: " Evidence supports the use of calcium, or calcium in combination with vitamin D supplementation, in the preventive treatment of osteoporosis in people aged 50 years or older. For best therapeutic effect, we recommend minimum doses of 1200 mg of calcium, and 800 IU of vitamin D (for combined calcium plus vitamin D supplementation . " The researchers found that supplementation is effective in the preventive treatment of osteoporotic fractures by up to 24 per cent. They added that over an average treatment duration of three to five years, the risk of fracture was reduced and was accompanied by a reduction of bone loss at the hip and spine. ........ .......The researchers also pointed out that on the basis of their recommended minimum dose of 1200 mg of calcium or 800 IU of vitamin D, many formulations of calcium or combined calcium with vitamin D tablets that are available contain insufficient quantities of the active ingredients ..... http://www.nutraingredients.com/news/ng.asp?id=79234-the-lancet- osteoporosis-vitamin-d-calcium Source: The Lancet Vol 370 August 25, 2007 Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older: a meta-analysis Authors: Benjamin Tang, Guy Eslick, Caryl Nowson, Caroline Smith, Alan Bensoussan Thanks Vince Quote Link to comment Share on other sites More sharing options...
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