Guest guest Posted October 8, 2007 Report Share Posted October 8, 2007 Dr.Robert Rowen,MD in his newsletter Second Opinion of September 2007, highlighted the increased risk of bone loss due to anti-convulsant drugs. Very often this common side effect is not communicated to patients. A study in 2006 published in Neurology 67(11):2005-14, evaluated the effects of Vitamin D supplementation at doses of 400 Internationa Units (IU) and 4,000 IU. The abstract of this study follows: _http://www.ncbi.nlm.nih.gov/sites/entrez?orig_db=PubMed & db=PubMed & cmd=Search & te\ rm=Neurology%5BJour%5D%20AND%2067% 5Bvolume%5D%20AND%2011%5Bissue%5D%20AND%202005-14%5Bpage%5D%20AND%202006%5Bpda t%5D_ (http://www.ncbi.nlm.nih.gov/sites/entrez?orig_db=PubMed & db=PubMed & cmd=Search & te\ rm=Neurology[Jour]%20AND%2067[volume]%20AND%2011[issue]%20AND%202005-1 4 %20AND%202006[pdat]) The researchers found that only at the higher dose of 4,000 IU was bone mineral density increased at several sites. If you are taking AED's, consider supplementing with Vitamin D, regardless of your blood level.Dr.Rowen recommends 5,000 IU per day. After reviewing the abstract(full text) is not freely avalable, I see there was a 3rd group of children and adolescents given 2,000 IU of vitamin D and Bone Mineral Density was signifacantly increased in Both groups receiving 400 and 2,000 IU. Since Vitamin D can accumulate in the system and reach a toxic level, a modified dosage for children and adolescents, based on size should be used. Arnold ************************************** See what's new at http://www.aol.com Quote Link to comment Share on other sites More sharing options...
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