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First Morning Urine pH Correlation with Acid Load

JoAnn Guest

Jan 23, 2007 09:32 PST

------------------------------

 

http://www.susanbrownphd.com/research_publications/urine.htm

 

The Osteoporosis Education Project has conducted several research

projects on acid-alkaline balance. One project was collaborative

research with Dr. Susan Whiting of the University of Saskatchewan on

the

relationship between first morning urine pH measurement and net acid

load.

For an abstract of these research findings as presented at the 2002

ASBMR meetings, see the " First Morning pH abstract " below.

Investigators

Susan Whiting, Ph.D., Janet Bell, and Susan E. Brown, Ph.D., CCN.

 

First Morning Urine Measured With pH Paper Strips Reflects Acid

Excretion

 

Susan J. Whiting, Janet Bell, College of Pharmacy and Nutrition,

University of Saskatchewan, 110 Science Place, Saskatoon, SK, S7N

5C9

and Susan E. Brown, Osteoporosis Education Project, 605 Franklin

Park

Drive, East Syracuse, NY 13057

 

Net acid excretion (NAE) is implicated in bone loss, as increased

calcium loss is seen with a high net acid excretion. Dietary protein

is

identified as a significant producer of acid whereas fruits and

vegetables may counteract this effect through the production of

metabolizable organic anions, which buffer acid.

 

Determination of NAE is important in recognizing the effect diet may

have on bone. Most commonly, a 24-hour urine collection is obtained

for

measurement of NAE where NAE is measured as titratable acidity minus

bicarbonate (TA-bicarb) plus ammonium (NH4+).

However, this measurement can be inconvenient and pH measured on

first

morning urine with semi-quantitative paper strips may be a practical

estimator of NAE. We recruited 23 (4M, 19F) healthy subjects age 20-

50 y

who recorded dietary intake for a day during which they collected

urine

from approximately 7 am to 11 pm in one container ( " day " ) and

approximately 11 pm to 7 am ( " overnight " ,ON) in a separate

container.

The first morning void contained ON urine. Subjects also provided a

two-hour fasting urine at 9 am. pH paper strips (colorpHast ®,

EM-Reagents, range 4-7) were used to measure pH of the ON urine, as

would be done in practice. A second set of strips (pH range 6.5-10)

was

used if the initial pH read high. Although measurement with pH paper

strips was not significantly correlated with 24-hr NAE, there was a

significant correlation with 24-hour TA-bicarb (r= -0.466, p<0.025).

Further, pH strip measures were significantly correlated with ON NAE

(r=

-0.710, p<0.005). We noted that ON NAE was correlated with total NAE

(r=0.504, p<0.014). We conclude there is useful information is

measuring

first morning urine pH (which provides pH of urine formed overnight)

to

obtain an estimate of acid excretion. pH paper strips appear to be

useful in the absence of longer (more invasive) urine collections.

 

The Osteoporosis Education Project has compiled other important acid

alkaline balance abstracts from the 2002 ASBMR conference.

 

 

JoAnn Guest

mrsjo-

www.geocities.com/mrsjoguest/Diets

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There's another real good article on http://royalrife.com about

correlating urine pH with breath-holding ability AND saliva and blood

pH to get a more accurate picture.

 

Bonnie.

 

 

, " JoAnn Guest "

<angelprincessjo wrote:

>

> First Morning Urine pH Correlation with Acid Load

> JoAnn Guest

> Jan 23, 2007 09:32 PST

> ------------------------------

>

> http://www.susanbrownphd.com/research_publications/urine.htm

>

> The Osteoporosis Education Project has conducted several research

> projects on acid-alkaline balance. One project was collaborative

> research with Dr. Susan Whiting of the University of Saskatchewan

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