Guest guest Posted November 2, 2006 Report Share Posted November 2, 2006 Carbohydrate Cravings, Depression, and Chromium Supplements JoAnn Guest Nov 02, 2006 07:36 PST http://www.willner.com/article.aspx?artid=42 The following is an excerpt from The Willner Window radio program, which can be heard every Sunday on WOR (710 AM) from 2 to 4 pm, or over the internet at www.wor710.com. Sam: Good afternoon everyone, this is .... Welcome to The Willner Window. For those of you who might be first-time listeners, the focus of this show is nutritional supplements–vitamins, herbs, homeopathic remedies–and their proper usage. With me this afternoon is . . Don, why don't you get us started? Don: I want to start off today's program with some comments on depression, and carbohydrate cravings. Some of you might be surprised that there is a connection. Dr. Podell: Well, there is a connect. Carbohydrate cravings, weight gain and unexplained fatigue are hallmark symptoms of atypical depression, a common, but frequently undiagnosed, depressive disorder estimated to affect as many as one-third of depressed patients. According to a 1990 World Health Organization study, depression is ranked as the fourth most deadly disease worldwide and is expected to be second only to heart disease by 2020. Sam: Now, as far as conventional medicine is concerned, there is currently no recognized treatment for carbohydrate cravings. But a new study, presented at the 24th International Neuropsycho-pharmacology Congress in Paris found that nutritional supplementation with chromium in the form of chromium picolinate significantly improved carbohydrate cravings, in addition to other distinct symptoms of atypical depression. Dr. Podell: This was a double-blind, placebo-controlled clinical trial in 113 patients diagnosed with atypical depression. As Sam said, they found that daily supplementation with chromium picolinate had significant anti-depressant effects in a patient sub-group with high levels of carbohydrate cravings. People with the highest levels of carbohydrate cravings at baseline experienced the most significant clinical response to the chromium picolinate. Sam: This study seems to correlate with the findings of another study, a pilot study published in the Journal of Biological Psychiatry. The study was conducted at the Duke University Medical Center Department of Psychiatry and Behavioral Sciences. According to Dr. Malcolm McLeod, a practicing psychiatrist, who collaborated on the Duke University study " We've seen remarkable improvements in depressed patients after supplementing with chromium picolinate, " He goes on to say " Chromium picolinate is a real breakthrough in providing safe and simple relief of atypical depression symptoms, many of which currently go untreated. " Don: Now, let's point out a couple of things. First, the results of these studies are being circulated widely by Nutrition 21, the folks who make chromium picolinate. That's not necessarily a bad thing. In fact, we should all salute Nutrition 21 for spending the money to support studies that provide us with proof that these supplements work. This is what we need. On the other hand, we have to keep a proper perspective. It's like that book that come out touting the benefits of a combination of glucosamine and chondroitin in treating joint pain. That combination did work. It does work. But the research supporting it did not compare the combination to each item alone. In other words, they didn't show that the combination was more effective than glucosamine alone. Or chondroitin alone. The supplement that they used happened to be supplied to the researchers by a company that marketed a combination. So that's what they used. And, again, there's nothing wrong with that. It's wonderful to see proof that a certain supplement works. But it's important to avoid reading more into such information than we should. Sam: So in the case of chromium picolinate and its relationship to carbohydrate cravings and depression, you are saying that we can conclude that this particular form of chromium is effective. It does not mean, on the other hand, that this is the only form of chromium that will have this action. Don: Exactly, Sam. How you utilize this data is up to you. If you happen to be a person who falls into this category, and who has not supplemented with chromium, I suspect you would feel most comfortable buying a chromium supplement using the picolinate form. On the other hand, I don't recommend you run to the medicine cabinet and toss any non-picolinate chromium that you might have in the trash can! Sam: What about dosage? How much chromium was used in the study? Don: Well, that leads to the other comment I want to make, Sam. The were using 600 mcg of chromium. Now this is a level that should probably be used only under a doctor's supervision. Most supplements have up to 200 mcg chromium, including most multivitamin products. The general feeling is that up to 300 mcg is harmless. Evidence of danger with higher doses is spotty at best, but prudence dictates caution. What you need to do is first look at your multivitamin. See how much is there. Probably 200 mcg. Then, look at your other supplements. If you are taking weight loss products, blood sugar control products, low-carb supplements–you may be getting extra chromium there, and that has to be added to what is in your multivitamin. Sam:Many appetite control, and weight loss products, contain added chromium. Don: This is not bad. It's added to products of this type for a good reason. It works. All we are trying to point out is that you should be sure to add up all the sources of chromium in your supplements when determining how much your total daily level might be. Dr. Podell: It does work. It is probably due to chromium`s essential role as an insulin co-factor. And, getting back to the studies we told you about, this may be the biological link between chromium, carbohydrate cravings and atypical depression. Insulin has effects on metabolic function that may impact serotonin levels in the brain. Impaired insulin function, which leads to poor glycemic control, is linked to a number of health conditions including diabetes. People with diabetes have an incidence of depression two times greater than in normal populations. Numerous clinical studies show that supplementation with chromium, in the form of chromium picolinate, is safe and helps improve insulin insensitivity and diabetes. JoAnn Guest mrsjo- www.geocities.com/mrsjoguest/Diets Quote Link to comment Share on other sites More sharing options...
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