Guest guest Posted October 2, 2006 Report Share Posted October 2, 2006 atracyphd2 Mon, 2 Oct 2006 03:38:12 EDT [drugawareness] Anna Nicole Smith's Son's Death From Serotonin Syndrome? The following quote is from an Associated Press article on the death of Anna Nicole Smith that according to Google hit over 1,200 news reports worldwide this past weekend. I had written to this reporter over two weeks ago to tell him what they would find caused Daniel's death, which was exactly what they did find this past week - the combination of two antidepressants and a pain killer: ____________ _________ ________ Smith wants others to learn from her son's death, Munroe told The Associated Press. " She wants to see exactly what happened in a final report because she wants to make sure it doesn't happen to someone else's son, " he said. Daniel Smith, who reportedly was hospitalized for depression and back pain before he traveled to Nassau, had been prescribed the antidepressant Lexapro, Wecht said. He said he had not determined whether Smith had also been prescribed Zoloft, the other antidepressant found in his system. The two drugs can be lethal when taken together or in sequence, according to Ann Blake Tracy, the Des Moines, Iowa-based director of the International Coalition for Drug Awareness. " The residue can stay there for some time, and if they're prescribed one after they've taken another, they can end up in trouble, " she said. ____________ _________ _________ __ Now those of you who have followed my research, heard me speak, or read articles I have written over the years are aware of how concerned I am about deaths like Daniel Smith's. I go absolutely ballistic when I hear of a doctor giving two of these drugs together or giving them back to back or weaning someone off one while starting them on another one. And I cannot believe how little warning there is given to patients if they take over the counter cough or cold meds with dextromethorphan in them or even dramamine for motion sickness that the combination with their antidepressant could cause Serotonin Syndrome which can prove fatal in a 24 hour period. What is Serotonin Syndrome? It is a condition in which serotonin levels become much too high. It is generally caused by mixing two serotonergic medications together. Daniel did not have a chance with three - Zoloft, Lexapro, and Methadone! Since the main function of serotonin is constriction of smooth muscle tissue (which all the organs, veins and arteries are) when one dies of Serotonin Syndrome it is generally caused by multiple organ failure as the organs clamp up and shut down. Tragically for many years a Google search for Serotonin Syndrome would produce our web site where it discusses my book explaining how deadly and dangerous this is and little to nothing else on the subject. Most of my information came from Dr. Kirk Mills who I consider a leading expert on this condition. Thankfully there is now a little more on the net about this deadly and generally fatal condition. The following quote from a study lists the symptoms: " Mental status changes are the most frequently reported symptoms [confusion (51%), agitation (34%), hypomania (21%), anxiety (15%) and coma (29%)] associated with serotonin syndrome. Other commonly reported features include motor abnormalities, cardiovascular changes, gastrointestinal problems and miscellaneous changes such as diaphoresis [sweating] and fever. " Now, those of you who have been on these drugs know all too well just how very often these drugs produce those side effects! So how often are patients going into high levels of serotonin that could become dangerous? I believe it is far more often than most realize. All the drug companies have ever wanted to discuss is low levels of serotonin, not what happens when the serotonin levels become too high. Do they really think the drug is going to put the brakes on when it reaches the " normal " level of serotonin? For those of you whose loved ones have suffered the mental status changes leading to tragedies that resulted in more than one life lost you understand firsthand that for Daniel and his family this tragedy could have been even worse. Spinning the wheel of toxic reactions generated by high serotonin is like playing Russian Roulette - you do not know which you are going to get. That is one reason why it is so difficult for people to understand all the many toxic reactions these drugs can produce whether they manifest as mental/behavioral or physical it is the same toxic reaction. Our prayers go out to Anna Nicole, Howard Stern and all those who loved Daniel as yet another family suffers yet another senseless loss to these very deadly drugs. This should make it all too obvious that the black box warnings we got on antidepressants in the last couple of years are not nearly enough!! As a society we continue to use these drugs with absolutely no education about how they work and the cautions that need to be taken - the same mistake we have made with drug after drug after drug until we finally know enough about them to pull them from the market. In the meantime too many innocent victims, literally used as guinea pigs, are left in the wake. And once again I ask how many must die before we wake up to the nightmare produced by this group of drugs? How many Daniel's, Matt's, Candace's, Julie's, Mark's, Aaron's, Jacob's, Conrad's, John's, Tracy's, Andrea's, etc., etc., etc., who could have made this world such a much brighter place, must we lose before we stop this wholesale slaughter? Ann Blake Tracy, Ph.D., Executive Director, International Coalition For Drug Awareness Website: _www.drugawareness. org_ (http://www.drugawar eness.org/) Author: Prozac: Panacea or Pandora? - Our Serotonin Nightmare & CD or audio tape on safe withdrawal: " Help! I Can't Get Off My Antidepressant! " Order Number: 800-280-0730 _http://www.boston. com/ae/tv/ articles/ 2006/09/28/ pathologist_ drug_combo_ killed _smith_son/_ (http://www.boston. com/ae/tv/ articles/ 2006/09/28/ pathologist_ drug_combo_ killed_smith_ son/) Smith accepts explanation of son's death Anna Nicole Smith, right, leaves the U.S. Supreme Court in Washington with her son Daniel Smith in this Feb. 28, 2006 photo. Smith's 20-year-old son died from a lethal combination of methadone and two antidepressant drugs, the U.S.-based pathologist who conducted a private autopsy said Wednesday, Sept. 27, 2006. Toxicology tests showed Daniel Smith had methadone, Zoloft and Lexapro in his system when he died Sept. 10 in a hospital room in the Bahamas where his mother was recuperating from giving birth to a daughter, according to Cyril Wecht. (AP Photo/Manuel Balce Ceneta) By Jessica Robertson, Associated Press Writer | September 28, 2006 NASSAU, Bahamas --Anna Nicole Smith believes a pathologist' s conclusion that her son died from an accidental lethal combination of drugs shows he didn't commit suicide and hopes that others will learn from the tragedy, a lawyer said Thursday. An American examiner hired by the family, Cyril Wecht, said 20-year-old Daniel Smith had methadone and two antidepressants in his system when he died Sept. 10 in his mother's hospital room in the Bahamas. Low levels of the three drugs interacted to cause an accidental death, Wecht said. " At least she knows the attacks on her son's reputation can be put to rest because it's clear he didn't intentionally take his life, " said Wayne Munroe, a Bahamian attorney for the 38-year-old reality TV star and former Playboy Playmate. Smith, who gave birth to a daughter three days before her son died at her bedside, is awaiting the conclusions of Wecht and the Bahamas pathologist who performed a separate official autopsy, Munroe said. Wecht is waiting for test results on tissue samples before he completes his final report. Smith wants others to learn from her son's death, Munroe told The Associated Press. " She wants to see exactly what happened in a final report because she wants to make sure it doesn't happen to someone else's son, " he said. Daniel Smith, who reportedly was hospitalized for depression and back pain before he traveled to Nassau, had been prescribed the antidepressant Lexapro, Wecht said. He said he had not determined whether Smith had also been prescribed Zoloft, the other antidepressant found in his system. The two drugs can be lethal when taken together or in sequence, according to Ann Blake Tracy, the Des Moines, Iowa-based director of the International Coalition for Drug Awareness. " The residue can stay there for some time, and if they're prescribed one after they've taken another, they can end up in trouble, " she said. Wecht said he did not know why Smith was taking methadone, a pain-reliever that is also used to ease heroin cravings for recovering addicts. The combination of the three drugs, even in low doses, could easily have killed Smith, said Lisa Johnson, a pharmacist at Cedars-Sinai Medical Center in Los Angeles. " The methadone will slow you down, but the other ones make your system speed up, so it's an odd combination, " she said. Chief Magistrate Roger Gomez said he has not received official toxicology results or a police report, which can determine whether a jury inquest is necessary. Wecht, a Pittsburgh-based forensic pathologist, plans to discuss his findings with Bahamas officials. Gomez said Wecht's toxicology results will not affect the Bahamian investigation. Daniel Smith, who appeared several times on the E! reality series " The Anna Nicole Show, " was the son of Anna Nicole and Bill Smith, who married in 1985 and divorced two years later. Smith married Texas oil tycoon J. Howard Marshall II in 1994, when she was 26 and he was 89. He died the following year. She has since been involved in legal disputes over the estate. ------ Associated Press writer Michael Melia in San Juan, Puerto Rico, contributed to this report. Quote Link to comment Share on other sites More sharing options...
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