Guest guest Posted September 24, 2006 Report Share Posted September 24, 2006 Your Cholesterol is Low? Watch Out! http://www.spacedoc.net/low_cholesterol.html Researcher Penelope K. Elias MD of Boston University reported recently in Psychosomatic Medicine that persons having naturally low cholesterol levels demonstrate poorer performance on a variety of cognitive tests. In this study, data was analyzed from 789 men and 1,105 women to examine the relationship between total cholesterol and cognitive performance. They found that those who had the lowest total cholesterol performed more poorly on tests of word similarities, word fluency and attention and concentration ability than patients with higher cholesterol levels. " It is not entirely surprising that lower cholesterol levels were associated with moderately lower levels of cognitive function, given that cholesterol is important in brain function, " reported lead study author, Doctor Elias. “The differences were not small,†she reported. Those in the lowest total cholesterol group (a cholesterol level of under 200) were 49 percent more likely to perform poorly and 80 percent more likely to perform very poorly than were participants in the highest total cholesterol group (240 to 380). The study was performed with people who had naturally low levels of cholesterol and were not being treated with anti-cholesterol drugs. " Naturally low levels of cholesterol and lowered levels of cholesterol may have very different ramifications for cognitive function, " Elias said. " Yet others have found that low serum cholesterol as a result of statin drug use is also associated with cognitive dysfunction. On their review of some 25,000 adverse drug reports taken from FDA’s Medwatch repository, Wagstaff and others discovered hundreds of reports of statin associated cognitive dysfunction such as extreme forgetfulness, confusion and disorientation in these statin users in their diligent search for transient global amnesia, their primary interest. Their report of 60 cases of statin associated TGA was published in Pharmacotherapy, August 2003, It was the first significant report of this subject in the medical literature. Another important report reflecting on the consequences of induced cholesterol lowering is that of Muldoon who reported 100% cognitive decline in statin users if sufficiently sensitive testing is used. He did two separate studies on this important subject, the first with Mevacor, the second with Zocor, both reported in the American Journal of Medicine, with identical results. Duane Graveline MD MPH Quote Link to comment Share on other sites More sharing options...
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