Guest guest Posted September 24, 2006 Report Share Posted September 24, 2006 Domingo, now that you mention Parkinson's, I have a well- referenced neurodegenerative illnesses protocol on my site,with explanations, that's has been helping a couple of patients with Parkinsons, several with Alzheimer's and a couple with multiple sclerosis, in addition to the supposedly fatal but now stopped and somewhat reversed inclusion body myositis, and the rheumatoid arthritis I think I already mentioned on this list and others. http://tinyurl.com/8j6oq In addition, new research I just saw prevented neurodegeneration quite well in other animals in vivo using high-niacin, a lot like Dr. Abram Hoffer's orthomolecular approach for other disorders. I'll try to find it again. Also, here more validation for my existing protocol from research that I haven't linked to yet: Neurodegeneration from mitochondrial insufficiency: nutrients, stem cells, growth factors, and prospects for brain rebuilding using integrative management. http://tinyurl.com/pg5bu (Altern Med Rev. 2005 Dec) " Exogenous toxins, such as mercury and other environmental contaminants, exacerbate mitochondrial electron leakage, hastening their demise and that of their host cells. Studies of the brain in Alzheimer's and other dementias, Down syndrome, stroke, Parkinson's disease, multiple sclerosis, amyotrophic lateral sclerosis, Huntington's disease, Friedreich's ataxia, aging, and constitutive disorders demonstrate impairments of the mitochondrial citric acid cycle and oxidative phosphorylation (OXPHOS) enzymes. Imaging or metabolic assays frequently reveal energetic insufficiency and depleted energy reserve in brain tissue in situ. Orthomolecular nutrients involved in mitochondrial metabolism provide clinical benefit. Among these are the essential minerals and the B vitamin group; vitamins E and K; and the antioxidant and energetic cofactors alpha-lipoic acid (ALA), ubiquinone (coenzyme Q10; CoQ10), and nicotinamide adenine dinucleotide, reduced (NADH). Recent advances in the area of stem cells and growth factors encourage optimism regarding brain regeneration. The trophic nutrients acetyl L-carnitine (ALCAR), glycerophosphocholine (GPC), and phosphatidylserine (PS) provide mitochondrial support and conserve growth factor receptors; all three improved cognition in double-blind trials. The omega-3 fatty acid docosahexaenoic acid (DHA) is enzymatically combined with GPC and PS to form membrane phospholipids for nerve cell expansion. Practical recommendations are presented for integrating these safe and well-tolerated orthomolecular nutrients into a comprehensive dietary supplementation program for brain vitality and productive lifespan. " Multiple sclerosis, an autoimmune inflammatory disease: prospects for its integrative management. http://tinyurl.com/ljjm6 (Altern Med Rev. 2001 Dec) " Dietary supplementation for MS minimally requires potent vitamin supplementation, along with the thiol antioxidants, the anti- inflammatory omega-3 fatty acids, and adaptogenic phytonutrients. Gut malabsorption and dysbiosis can be corrected using digestive enzymes and probiotics. " Prebiotics and probiotics are an important part of neurodegenerative illness correction but there's much more to it; I hope you find my protocol and its links to be fascinating and empowering. Duncan Crow > Posted by: " Domingo Pichardo " dpichardo3 modamugerione > Sat Sep 23, 2006 6:04 pm (PDT) > > Thank you Duncan Crow for your most educational answer... I was going > to ask my mother's doctor for a prescription for it to treat her > chronic constipation (she has Parkinson) and is taking a stool softner > (Docucate Sodium) but I will go with the Inulin instead! Dom > > Duncan Crow wrote: > > > > PREbiotics (food for probiotics) vary in their support for different > > bacteria; some have wide appeal and some are very specific, so, a > > better question to apply to a prebiotic is more like, " which > > organisms are going to use it the fastest? " and the answer will be > > as varied as its paticular specicificity as a prebiotic and the > > paticulars of the starter culture. > > > > Lactulose is used for hydrogen breath testing; because hydrogen is > > not produced by bifidobacteria or lactobacilli, obviously it appeals > > to some non-probiotic bacteria too. Hydrogen-using bacteria convert > > hydrogen to methane, which is converted by methane-using bacteria to > > methanol. In dysbiosis, methanol, a toxin, is produced in fairly > > large quantities. > > > > In this in-vivo hog study (PMID: 12420113) lactulose increased > > Clostridia perfringens, which like C. difficile is a particularly > > troublesome pathogen in humans that often causes terminal diarrhea > > in the elderly, more than it increased bifidobacteria. > > > > So, after all that the short answer is that you could select from > > many prebiotics, lactulose included, and get varied results. I chose > > inulin over the artificial prebiotics because it is a quite specific > > prebiotic even in " native " unrefined form, it is a very specific > > pebiotic when shorter chains are removed, it is demonstratably > > deficient in the modern diet, and we and our gut bacteria evolved > > with it. Note that inulin does not support clostridia. > > > > We discuss this kind of thing in detail on the candidiasis list. > > > > Duncan Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 25, 2006 Report Share Posted September 25, 2006 Thanks! I am digesting a lot of this info! You have a great website! It maybe too late for my mother but it is probably a good preventative strategy for me and my sister!!! Thanks again! Domingo Duncan Crow wrote: > > Domingo, now that you mention Parkinson's, I have a well- > referenced neurodegenerative illnesses protocol on my site,with > explanations, that's has been helping a couple of patients with > Parkinsons, several with Alzheimer's and a couple with multiple > sclerosis, in addition to the supposedly fatal but now stopped > and somewhat reversed inclusion body myositis, and the rheumatoid > arthritis I think I already mentioned on this list and others. > http://tinyurl. com/8j6oq <http://tinyurl.com/8j6oq> > > In addition, new research I just saw prevented neurodegeneration > quite well in other animals in vivo using high-niacin, a lot like > Dr. Abram Hoffer's orthomolecular approach for other disorders. > I'll try to find it again. > > Also, here more validation for my existing protocol from research > that I haven't linked to yet: > > Neurodegeneration from mitochondrial insufficiency: nutrients, > stem cells, growth factors, and prospects for brain rebuilding > using integrative management. > http://tinyurl. com/pg5bu <http://tinyurl.com/pg5bu> (Altern Med Rev. > 2005 Dec) > > " Exogenous toxins, such as mercury and other environmental > contaminants, exacerbate mitochondrial electron leakage, > hastening their demise and that of their host cells. Studies of > the brain in Alzheimer's and other dementias, Down syndrome, > stroke, Parkinson's disease, multiple sclerosis, amyotrophic > lateral sclerosis, Huntington's disease, Friedreich's ataxia, > aging, and constitutive disorders demonstrate impairments of the > mitochondrial citric acid cycle and oxidative phosphorylation > (OXPHOS) enzymes. Imaging or metabolic assays frequently reveal > energetic insufficiency and depleted energy reserve in brain > tissue in situ. > > Orthomolecular nutrients involved in mitochondrial metabolism > provide clinical benefit. Among these are the essential minerals > and the B vitamin group; vitamins E and K; and the antioxidant > and energetic cofactors alpha-lipoic acid (ALA), ubiquinone > (coenzyme Q10; CoQ10), and nicotinamide adenine dinucleotide, > reduced (NADH). > > Recent advances in the area of stem cells and growth factors > encourage optimism regarding brain regeneration. The trophic > nutrients acetyl L-carnitine (ALCAR), glycerophosphocholi ne > (GPC), and phosphatidylserine (PS) provide mitochondrial support > and conserve growth factor receptors; all three improved > cognition in double-blind trials. The omega-3 fatty acid > docosahexaenoic acid (DHA) is enzymatically combined with GPC and > PS to form membrane phospholipids for nerve cell expansion. > Practical recommendations are presented for integrating these > safe and well-tolerated orthomolecular nutrients into a > comprehensive dietary supplementation program for brain vitality > and productive lifespan. " > > Multiple sclerosis, an autoimmune inflammatory disease: prospects > for its integrative management. > http://tinyurl. com/ljjm6 <http://tinyurl.com/ljjm6> (Altern Med Rev. > 2001 Dec) > > " Dietary supplementation for MS minimally requires potent vitamin > supplementation, along with the thiol antioxidants, the anti- > inflammatory omega-3 fatty acids, and adaptogenic phytonutrients. > Gut malabsorption and dysbiosis can be corrected using digestive > enzymes and probiotics. " > > Prebiotics and probiotics are an important part of > neurodegenerative illness correction but there's much more to it; > I hope you find my protocol and its links to be fascinating and > empowering. > > Duncan Crow > > > Posted by: " Domingo Pichardo " dpichardo3 (AT) verizon (DOT) net > <dpichardo3%40verizon.net> modamugerione > > Sat Sep 23, 2006 6:04 pm (PDT) > > > > Thank you Duncan Crow for your most educational answer... I was going > > to ask my mother's doctor for a prescription for it to treat her > > chronic constipation (she has Parkinson) and is taking a stool softner > > (Docucate Sodium) but I will go with the Inulin instead! Dom > > > > Duncan Crow wrote: > > > > > > PREbiotics (food for probiotics) vary in their support for different > > > bacteria; some have wide appeal and some are very specific, so, a > > > better question to apply to a prebiotic is more like, " which > > > organisms are going to use it the fastest? " and the answer will be > > > as varied as its paticular specicificity as a prebiotic and the > > > paticulars of the starter culture. > > > > > > Lactulose is used for hydrogen breath testing; because hydrogen is > > > not produced by bifidobacteria or lactobacilli, obviously it appeals > > > to some non-probiotic bacteria too. Hydrogen-using bacteria convert > > > hydrogen to methane, which is converted by methane-using bacteria to > > > methanol. In dysbiosis, methanol, a toxin, is produced in fairly > > > large quantities. > > > > > > In this in-vivo hog study (PMID: 12420113) lactulose increased > > > Clostridia perfringens, which like C. difficile is a particularly > > > troublesome pathogen in humans that often causes terminal diarrhea > > > in the elderly, more than it increased bifidobacteria. > > > > > > So, after all that the short answer is that you could select from > > > many prebiotics, lactulose included, and get varied results. I chose > > > inulin over the artificial prebiotics because it is a quite specific > > > prebiotic even in " native " unrefined form, it is a very specific > > > pebiotic when shorter chains are removed, it is demonstratably > > > deficient in the modern diet, and we and our gut bacteria evolved > > > with it. Note that inulin does not support clostridia. > > > > > > We discuss this kind of thing in detail on the candidiasis list. > > > > > > Duncan > > Quote Link to comment Share on other sites More sharing options...
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