Licorice

[Guest guest]

on 11/16/00 12:20 AM, Todd at wrote:

 

Here's a translation by Heiner Fruehauf of a passage about gan cao from Zhang Xichun's Chinese at Heart But Open to the West: An Integrated Approach to Traditional and Modern Medicine (Yixue Zhongzhong Canxi Lu, 1923), Fruehauf, classnotes

 

 

 

Thanks for plugging this in, Todd. This answers all my questions.

 

 

[Guest guest]

Licorice

JoAnn Guest

Aug 17, 2006 18:56 PDT

 

 

 

Consuming a diet rich in plant foods will provide a milieu of

phytochemicals, non-nutritive substances in plants that have been

associated with protection from and/or treatment of conditions such

as

cardiovascular disease and cancer. Licorice root is among the foods

and

herbs with the highest anticancer activity.

**Phytochemicals: Health Protective Effects. Can J Diet Pract Res

1999;60(2):78-84

 

Glabridin from licorice is a phytoestrogen, binding to the human

estrogen receptor. Glabridin and its derivatives inhibit the growth

of

breast cancer cells.

**Estrogenic and antiproliferative properties of glabridin from

licorice

in human breast cancer cells. Cancer Res 2000 Oct 15;60(20):5704-9

 

Licorice extract showed a significant protective effect against

cytotoxic N-nitrosamines NDMA, NYPR, NDBA, and NPIP. N-nitrosamines

are

common environmental carcinogens.

 

**Protective Effect of Broccoli, Onion, Carrot, and Licorice

Extracts

against Cytotoxicity of N-Nitrosamines Evaluated by

3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium Bromide Assay.

J

Agric Food Chem. 1998 Feb 16;46(2):585-589.

 

In a study of a 100-day experimental intoxication with lead and

chromium, licorice diminished the manifestations of adverse effects

of

lead and chromium on the functional status of digestive organs.

**[untitled}. Gig Sanit 2001 Mar;2:46-49

 

In an animal experiment, glycyrrhizin (GR), a component of licorice

root

extract, stimulated the immune system defense against herpes simplex

infection. Mice suffering from herpes simplex encephalitis increased

their survival rate by 2.5 times.

 

**Glycyrrhizin increases survival of mice with herpes simplex

encephalitis. Acta Virol 2001 Feb;45(1):51-4

 

The flavonoid glabridin (derived from licorice) acts synergistically

with lycopene, as an effective antioxidant against LDL oxidation.

 

These observations suggest a superior antiatherogenic characteristic

to

a combination of different natural antioxidants over that of an

individual one.

 

**Lycopene synergistically inhibits LDL oxidation in combination

with

vitamin E, glabridin, rosmarinic acid, carnosic acid, or garlic.

Antioxid Redox Signal 2000 Fall;2(3):491-506

 

Dibenzoylmethane (DBM), a constituent of licorice, exerts a strong

inhibitory action on mammary carcinogenesis in mice. Feeding 1% DBM

to

laboratory mice inhibited formation of DMBA-DNA adducts in mammary

glands and lowered the proliferation rate of the mammary gland in

vivo.

**Inhibition by dietary dibenzoylmethane of mammary gland

proliferation,

formation of DMBA-DNA adducts in mammary glands, and mammary

tumorigenesis in Sencar mice. Cancer Lett 2001 Jul 26;168(2):125-132

 

A constituent of licorice has powerful cancer fighting properties.

Glycyrrhetinic acid, a strong 11beta-HSD inhibitor isolated from

licorice, induces apoptosis (cell suicide) of murine thymocytes via

accumulation of corticosterone.

**Magnolol from Magnolia officinalis inhibits 11beta-hydroxysteroid

dehydrogenase without increases of corticosterone and thymocyte

apoptosis in mice. Planta Med 2001 Feb;67(1):33-37

 

In atherosclerotic apolipoprotein E-deficient mice, consumption of

flavonoids from licorice decreased LDL oxidation, LDL retention, and

LDL

aggregation and attenuated macrophage foam cell formation and

atherosclerosis.

 

**Macrophage foam cell formation during early atherogenesis is

determined by the balance between pro-oxidants and anti-oxidants in

arterial cells and blood lipoproteins. Antioxid Redox Signal

1999;1(4):585-594

 

Licorice is an herbal drug that has been used extensively and its

clinical efficacy documented.

**The plant kingdom as a source of anti-ulcer remedies. Phytother

Res

2000 Dec;14(8):581-591

 

Lycopene acts synergistically, as an effective antioxidant against

LDL

oxidation, with several natural antioxidants including the flavonoid

glabridin (derived from licorice). These observations suggest a

superior

antiatherogenic characteristic to a combination of different natural

antioxidants over that of an individual one.

 

**Lycopene synergistically inhibits LDL oxidation in combination

with

vitamin E, glabridin, rosmarinic acid, carnosic acid, or garlic.

Antioxid Redox Signal 2000 Fall;2(3):491-506

 

 

JoAnn Guest

mrsjo-

www.geocities.com/mrsjoguest/Diets