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Cardiovascular Disease JoAnn Guest

Jun 13, 2006 20:34 PDT

 

 

 

 

Here are some compelling statistics on Cardiovascular Disease from

the

American Heart Association's 2001 Heart and Stroke Statistical

Update

2000:

Cardiovascular Disease (CVD) has been the number one cause of death

in

the U.S. since 1990. Almost 60 million Americans have one or more

types

of CVD; 50 million have high blood pressure.

Over 12 million Americans have coronary heart disease.

One in five females have some form of CVD. One in three men develop

CVD

before the age of 60, versus one in 10 for women.

 

CVD alone has claimed more lives each year than the next seven

leading

causes of death combined. Each day, more than 2,600 Americans die of

CVD

-- that's one death per 33 seconds.

 

Heart disease or coronary artery disease is caused by

atherosclerosis.

Atherosclerosis is a condition in which cholesterol-rich plaque

builds

up along the arterial walls.

 

High cholesterol levels can play a part, though they do not always

result in atherosclerosis and atherosclerosis can exist with normal

cholesterol levels. But when the coronary arteries are affected, the

condition is called coronary artery disease.

 

How does atherosclerosis develop?

Atherosclerosis seems to begin with an injury to the endothelial

lining

along the artery wall. Interestingly, this process actually can

begin at

an early age.

 

Once an injury occurs, " white blood cells " such as monocytes and

macrophages, along with lipids, begin to *accumulate* along the

inner

layer of the artery as well as the muscle layer.

Smooth muscle cells begin to multiply from the irritation and

eventually form a " plaque " .

 

Platelets and other blood clotting factors stick to the rough

surface of the artery wall, forming a thrombus (clot).

 

A clot can continue to grow until it completely blocks an artery,

cutting off the oxygen supply to a vital organ.

 

Or a clot can break free from the vessel wall and become lodged

somewhere else further downstream. This could lead to a heart attack

or

stroke if the clot completely blocks the blood and oxygen supply to

a

major artery leading to the heart or brain.

 

Although initially there are no symptoms, once the arteries become

very

constricted, one may experience pressure or tightening in the chest

due

to a *lack of oxygen* being delivered to the heart (angina).

There may also be cramping in the lower extremities due to blockage

in

the peripheral veins (peripheral vascular disease).

 

Factors associated with heart disease

 

Researchers now believe that many different problems can lead to

heart

disease. And cholesterol can often play a key part.

Cholesterol is a waxy, fat-like substance made by the liver.

It is an essential component of cell membranes and used to produce

hormones and vitamin D.

 

Cholesterol is carried through the body attached to two different

compounds called " lipoproteins " : low-density lipoproteins (LDL) and

high-density lipoproteins (HDL).

 

LDL is commonly known as the " bad cholesterol " it carries

cholesterol

from the liver throughout the body, making it

available to be deposited in artery walls.

 

HDL is known as the " good cholesterol " ; it essentially " picks up "

cholesterol from the *arteries* and " delivers " it to the

liver to be recycled or eliminated from the body.

 

The body needs cholesterol to function normally but too much of it

in

the blood, or too much of the wrong kind (LDL), add up

to trouble.

 

The factors leading to heart disease are as follows:

High total cholesterol – especially high LDL levels – These two

factors

combine to form a well

known risk factor for heart disease (though people can have heart

disease without having high cholesterol). Dietary and nutritional

supplement treatment of high cholesterol

levels ARE effective.

 

Low HDL cholesterol and high *triglyceride* levels – This is a

different

pattern than high total and LDL cholesterol

although someone may have both.

 

This pattern, associated with *insulin resistance*, is also

genetically

driven and appears to affect as many as 30% of the population.

It carries with it a high risk of high blood pressure and diabetes

as

well as heart disease.

 

Dietary and nutritional supplement treatment for this pattern are

different from those for high total and LDL cholesterol levels.

Here, lifestyle changes are generally quite effective.

 

Elevated *homocysteine* levels –

This risk factor for heart disease is unrelated to cholesterol

levels at

all. Homocysteine is an amino acid that can accumulate in the blood

when

a person does not have enough folic acid and vitamin B6 in their

system.

 

 

Folic acid " requirements " for some individuals may be much greater

than

the RDA of 400 mcg.

 

Smoking – This habit alone can increase risk of heart disease.

Smoking

increases " oxidation " in the body and is harmful to (constricts) the

arteries leading to the heart.

 

Family history – Genetic tendencies, however, can be countered by a

healthy lifestyle in most instances.

If you have a family history of heart disease, we recommend

paying particular attention to diet, exercise, stress reduction and

supplements.

 

 

Fish oils –

The omega-3 fatty acids in fish and fish oil supplements have

been shown to be an effective preventive strategy against heart

disease.

 

 

They can lower triglyceride levels, increase 'HDL'(good)

cholesterol,

help minimize inflammation and blood clotting, and keep blood

vessels

healthy.

 

Coenzyme Q10 – This antioxidant is thought to be one of the most

important antioxidant supplements and is used for protection against

many forms of

cardiovascular disease. It helps protect LDL cholesterol from

oxidation, maintain healthy blood vessels, protects against clots

and

'plaque' rupture, and supports optimal functioning of the heart

muscle.

--

What you can do to lower your cholesterol

 

Reduce greatly the amount of saturated fat you eat. The richest

sources

of saturated fat (fat that is usually solid at room

temperature) in the diet are dairy foods, especially milk, cheese,

butter and cream. Red meat,coconut oils and palm oils also have

excessively high saturated fat content .

 

Avoid trans–fats.

If you find " partially hydrogenated oil " listed in the ingredient

list

on margarines and other food labels, find a healthier substitute.

There

are spreads available which are totally free from trans-fat.

Spectrum

spreads and Earth Balance spreads provide good substitutes for

trans-fatty margarines.

http://www.spectrumnaturals.com

 

Trans-fat is also found in processed food (canned and boxed) and

snack

foods such as chips, crackers, cookies, and processed, white

sandwich

buns and bread. It is found

in oils used in restaurants to cook fast foods, i.e. battered fish,

french fries, doughnuts and movie popcorn.

 

Substitute non-gmo soy protein for animal protein.

 

The protein in non-gmo soy foods help to lower your cholesterol

levels.

Try to incorporate at least two servings a day into your diet.

Choose

from organic tofu, tempeh, organic soy milk and black soybeans

(canned

is fine).

http://www.edenfoods.com

 

Use fresh garlic regularly in your meals. Garlic has been known to

lower

cholesterol levels and high blood pressure -- and it tastes

wonderful,

too. Use one or two fresh, baked or lightly cooked cloves each day.

 

Drink green tea daily. The antioxidants in green tea help lower

cholesterol and prevent the cholesterol in your blood from

oxidizing.

 

*Soluble* fiber.

 

Soluble fiber has a powerful cholesterol-lowering effect. The best

sources of soluble fiber are cooked dried beans, legumes,

lentils,pears,

 

apples, citrus fruits, oats and oat bran (microwaved and instant

oats do

not provide the same benefit) barley, peas, pumpkin and carrots.

 

Nutritional supplements and cholesterol-

 

Guggulipid – This extract of an Ayurvedic herb (Commiphora mukul)

lowers cholesterol levels to the same degree as many medications.

 

Coenzyme Q10 (CoQ10) – CoQ10 is a powerful antioxidant that protects

LDL

cholesterol from oxidation and re-energizes the mitochondria in the

heart cells, which is where energy metabolism occurs.

This nutrient is very important

for the heart cells of patients with heart failure. CoQ10 may also

help

lower blood pressure.

 

Fish oil – Though omega-3 fatty acids in fish oil don't specifically

lower total or LDL cholesterol levels, they do seem to reduce the

risk

of heart disease by reducing platelet stickiness, inflammation and

triglyceride levels.

 

Insulin Resistance (high triglycerides and low HDL cholesterol)-

Insulin resistance is now being recognized as an important and

common

condition associated with heart disease, as well as diabetes and

high

blood pressure. It affects an estimated 25-to-30% of the non-

diabetic

population.

 

It is primarily characterized by high triglyceride and low

HDL cholesterol levels, although high total cholesterol may also be

seen.

Genetic factors play a significant role, but diet and lifestyle

changes can make a big difference (an even bigger difference than in

the previously discussed condition of high total and high LDL

cholesterol).

 

A little background:

Insulin is a hormone that facilitates the transport of glucose from

the

blood into cells where it is used as fuel. When blood sugar rises

after

a meal, the pancreas secretes insulin into the bloodstream. With

insulin

resistance, the normal amount of insulin

secreted is not enough to move glucose into the cells – thus the

cells

are " resistant " to the action of insulin. To compensate, the

pancreas

secretes even more insulin in order to maintain fairly normal blood

sugar movement into cells and a normal blood sugar level.

 

The resulting high levels of insulin, however, have several negative

effects -- on the enzymes in the liver that produce cholesterol, and

on the kidney leading to high blood pressure, as well as on the

enzymes

in cells that regulate inflammation.

 

Eventually, blood sugar levels rise

either because the pancreas stops producing insulin or the cells

become

more and more resistant to the insulin that is produced. The body's

inability to adequately compensate leads to diabetes.

 

Having diabetes, even in the early stages, significantly increases

the

risk of heart disease. Early diabetes may be the first time insulin

resistance is recognized.

 

Warning signs and diagnosis of insulin resistance?

 

Interestingly, although insulin resistance is usually seen in

people who are overweight, thin people can also have the problem and

be

at the same risk for heart disease, high blood pressure and

diabetes.

 

The easiest way to diagnose the problem is to take a blood test that

looks for the following indicators.

A low HDL cholesterol is almost always seen, along with a high

triglyceride level. You may also check for a high fasting insulin

level.

A high uric acid level sometimes accompanies these values.

 

What can you do about insulin resistance?

 

Watch out for processed refined carbs such as white bread and

refined

white sugars – The classic lowfat, high refined

carbohydrate diet that was the standard recommendation for

preventing or

 

treating heart disease for years can actually make insulin

resistance

worse.

 

Refined Carbohydrates (refined starches and sugars) raise blood

sugar

levels and 'trigger' the release of insulin.

A moderately low carbohydrate diet (40-to-45% of calories)

emphasizing

complex carbs and a

low glycemic index source of carbohydrate (those that raise blood

sugar

levels slowly rather than quickly) is recommended. In general, foods

very rich in 'fiber' are healthy.

 

 

Cut *saturated* fats, but keep *monosaturated* fats -

Include moderate amounts of monounsaturated fat (30 to 35% of

calories)

rather than following the typical " low-fat " diet.

 

However, in this condition, as with high total and LDL cholesterol,

saturated fat makes the situation worse.

Eat generous amounts (5 or more servings) of organic vegetables and

one

to two servings of low-glycemic index fruit every day.

 

Lose weight if you are overweight. Even small amounts of weight lost

can

improve insulin resisitance.

Exercise – Vigorous aerobic exercise decreases the cells' resistance

to

insulin.

 

Eat fish frequently – The best are cold water fish like alaskan

salmon,water packed sardines and mackerel that are high in omega-3

fatty

acids.

 

This type of fat seems to improve cells' " response " to insulin.

Eat small, frequent meals to keep blood sugar levels as stable as

possible.

---

Nutritional supplements and insulin resistance

 

Coenzyme Q10 (CoQ10) – CoQ10 is a powerful antioxidant that has been

shown to be beneficial for heart health by protecting LDL

cholesterol

from oxidation and re-energizing the mitochondria in the heart

cells,

which is where energy metabolism occurs. This nutrient is very

important

 

for the heart cells of patients with heart failure. CoQ10 may also

help

lower blood pressure.

 

Alpha-lipoic acid – This antioxidant nutrient improves the cells'

response to insulin and can reduce blood sugar levels.

 

Magnesium – Higher insulin and blood sugar levels are seen in people

with low plasma magnesium levels and magnesium supplementation

improves

insulin resistance in animal studies

 

Chromium – It improves glucose utilization in people with high blood

sugar levels and improves insulin resistance in animals.

 

High homocysteine –

Homocysteine is an amino acid that is produced in the body from

another

amino acid, namely *methionine*.

One of methionine's main functions is to provide methyl groups for

cellular reactions.

A methyl group is a small, simple chemical fragment consisting of

one

carbon molecule and three hydrogen molecules.

When methionine donates a methyl group for a

cellular reaction, it becomes homocysteine.

 

Typically homocysteine then receives another methyl group from

either

folic acid or vitamin B6 and is turned back into methionine. Vitamin

B12

acts as a cofactor for this reaction.

 

In short, if you don't have enough of certain critical B vitamins,

your

homocysteine level rises. A high homocysteine level is primarily a

sign

of an inadequate intake of folic acid or vitamin B6.

 

Factors that control homocysteine levels:

 

Genetics – There are genetic variations in folic acid absorption and

utilization. Some individuals therefore need much more folic acid

than

the RDA of 400 mcg.

 

Stress – Epinephrine and norephinephrine are stress induced

neurotransmitters. Their metabolism in the liver involves

methylation,

a process that uses methyl groups, and can increase need for methyl

donors like folic acid.

 

Coffee consumption – As coffee consumption increases, homocysteine

levels increase

Increase the amount of folic acid, vitamin B6 or vitamin B12 in your

diet and supplement regimen.

 

What is the relationship between homocysteine, heart disease and

strokes?

High homocysteine levels are associated with atherosclerosis.

Homocysteine is thought to be damaging to the lining of blood

vessels,

leading to atherosclerosis.

 

As homocysteine levels increase, the risk of heart disease and

stroke

increase. (High homocysteine levels are also associated with risk of

cancer and cervical dysplasia, as well as neural

tube birth defects like spina bifida.)

 

Diagnosing high homocysteine

Although the reference ranges for homocysteine from most labs show a

normal range up to 12, homocysteine researchers are suggesting that

any

level over 8 should be treated.

 

Nutritional supplements and homocysteine

Folic acid, vitamin B6, vitamin B12 and betaine are all involved in

the

process of adding a methyl group back to the " homocysteine "

molecule.

Supplementation of these nutrients will bring high homocysteine

levels

down.

 

Although the B vitamins (the first three in the list) are found

in multivitamins, we recommend higher doses depending on your

homocysteine level.

If your homocysteine level is high, we recommend

retesting it six months after you begin taking supplements.

 

Angina Pectoris

 

Angina is chest pain that can occur when there is a dramatic

decrease in

 

the blood supply to the heart, an increased demand for oxygen by the

heart, or a combination of both. It is a symptom of heart disease or

coronary artery disease.

 

If the walls of the blood vessels are hard and unable to relax (for

example, as a result of atherosclerosis), the vessels will not be

able

to 'dilate' properly, which slows down blood

flow.

 

Increasing physical or emotional exertion increases the demand for

oxygen. If the arteries are so blocked that the heart cannot receive

sufficient oxygen to meet its needs, angina can result.

 

What are the factors that cause angina or an oxygen deficit to the

heart?

 

Most often, angina is caused by coronary artery disease. In some

cases

angina can result from a narrowing of the aorta (a major vessel

leading

to the heart) due to an aortic valve abnormality;

arterial spasms causing a temporary constriction in the artery; or

an

enlarged heart, in which the blood supply is no longer adequate to

supply sufficient oxygen to the heart.

 

What are the symptoms?

Look for chest pain that is intermittent, brief and persistent. The

length of an attack and the severity can vary. The pain feels like a

tightness or pressure in the chest that may radiate to the neck,

along

the left shoulder or down the left arm.

 

Some experience difficulty breathing and nausea.

 

What triggers an angina attack?

Angina can be triggered by emotional or physical stress, exerting

oneself after a meal, or extreme temperature changes. Cigarette

smoking

can also bring on an angina attack.

 

What can I do to reduce my risk of angina?

Follow a heart healthy diet as outlined above.

 

Nutritional supplements and angina

 

Coenzyme Q10 (CoQ10) – CoQ10 is a powerful antioxidant that has been

shown to be beneficial for heart health by protecting LDL

cholesterol

from oxidation and re-energizing the mitochondria in the heart

cells,

which is where energy metabolism occurs. This nutrient is very

important

 

for the heart cells of patients with heart failure. CoQ10 may also

help

lower blood pressure.

 

Hawthorne Berry- Hawthorne is another antioxidant with heart-

enhancing

properties. Hawthorne may help improve coronary artery blood flow

and

circulation to the extremities of the body, therefore improving

symptoms

of angina.

 

L – arginine –

L –arginine is a precursor to nitric oxide which relaxes

blood vessels in the heart and has been shown to help angina.

 

High Blood Pressure (Hypertension)

Hypertension is the most common form of cardiovascular disease in

America, affecting about 50 million people.—that's close to one out

of

four adults.

High blood pressure is defined as a reading above

140/90mmHg (systolic/diastolic). (Systolic pressure (the first

number)

measures the pressure in the arteries when the heart contracts.

Diastolic pressure (the second number) measures the pressure in the

arteries when the heart is relaxing and filling with blood.)

 

What causes high blood pressure?

 

The heart pumps blood through your arteries (large blood vessels),

pushing the blood against the artery walls with a force that is

measured

as our " blood pressure. " Normal blood pressure is around 120/80 mm

Hg.

 

High blood pressure occurs when the artery walls lose their

elasticity

and cause the pressure of the blood moving through the arteries to

rise.

 

This excessive pressure makes the heart work harder, and can

eventually

lead to an enlarged heart (cardiomegaly), as well as damage to blood

vessels in the kidneys and brain.

 

Doctors cannot pinpoint the precise cause of 90 percent of high

blood

pressure cases,also known as " essential hypertension. " However, they

do

know that certain factors can increase the risk of developing high

blood

pressure:

 

Stress can cause hypertension by activating the sympathetic nervous

system, causing the arteries to constrict.

 

Ingesting large amounts of *sodium* in the diet can cause excess

water

retention,

expand blood volume and ultimately increase blood pressure. Diets

rich

in processed foods is typically high in sodium.

 

A diet low in magnesium and potassium can increase blood pressure

 

Insulin resistance can increase blood pressure by causing the

kidneys to

retain sodium.

 

What can you do to lower your blood pressure? Include generous

amounts

of fruits and

vegetables also follow a diet

relatively low in fat and sodium.

 

Researchers have shown that diets rich in potassium, calcium and

magnesium, and low in sodium, (2,400 mg or less) play an important

role

in maintaining healthy blood pressure levels.

 

These are the high points of the diet:

Eat 8-10 servings of fruit and vegetables servings per day. .

Consume 4-5 servings of nuts, seeds and dry beans per week (2 Tbsp

nuts

or seeds, or 1/2 cup cooked dried beans).

 

Eat plenty of fish – Include at least three servings of fish a week,

emphasizing cold water fish like alaskan salmon and water packed

sardines that are

rich in omega-3 fatty acids.

 

Coffee- The caffeine in coffee, tea and sodas can contribute to high

blood pressure.

 

Avoid processed foods -- These are the biggest sources of sodium in

today's diet.

 

Relax –Meditation, yoga, breathing exercises or biofeedback are all

relaxation techniques that can help lower blood pressure.

 

Don't smoke – Smoking contributes to cardiovascular diseases – and

many

other life-threatening conditions as well.

 

Nutritional supplements and high blood pressure

 

Calcium and magnesium – Inadequate intake of Magnesium has been

associated with high blood pressure.

 

Vitamin C – A supplement of this antioxidant vitamin has been shown

to

lower blood pressure in people with mild to moderate

hypertension.

 

Stroke

Stroke is the third leading cause of death when considered

separately

from other types of cardiovascular disease, accounting for about one

out

of every 14.5 deaths in the U.S., according to the American Heart

Association.

 

What is a stroke?

 

A stroke, also known as a cerebrovascular accident, is the death of

brain tissue caused from a lack of blood flow and " insufficient

oxygen "

to the brain.

 

The brain receives about 25 percent of the body's oxygen

supply from a continuous blood flow through two main arteries, the

carotid arteries (that come up through both sides of the front of

the

neck) and the basilar artery (which forms at the base of the skull

from

the vertebrae arteries).

 

Strokes (like heart attacks) can often result from a blockage in a

blood

 

vessel that reduces or cuts off oxygen supply to the cells,

resulting in

 

the death of the tissue. It only takes a short period of time

without

oxygen to cause damage to the brain.

 

There are 2 main classifications of strokes:

 

Ischemic-

The blood supply is cut off to part of the brain, either due

to atherosclerosis or a blood clot. Infections, inflammation or

certain

*medications* can all contribute to ischemic strokes. These strokes

are

the most common type, causing about 80 percent of all stroke cases.

 

Hemorrhagic –

These strokes comprise the remaining 20 percent of cases.

Hemorrhagic strokes are caused from a ruptured blood vessel,

preventing

normal blood flow and causing bleeding into an area of the brain.

 

They can be the result of hypertension, which causes excessive

pressure

on the arterial walls that may already be damaged by

arteriosclerosis. A

 

ruptured aneurysm (the rupture of a weakened area in the blood

vessel

wall), can also cause a hemorrhagic stroke.

 

What can I do to prevent a stroke?

 

Focus on your diet - The diets outlined for high blood pressure and

heart disease are useful in preventing strokes as well.

Exercise – People who exercise consistently have a lower risk for

having

 

a stroke. .

 

Limit alcohol – If you drink alcohol, do so only in moderation.

Moderate

alcohol intake is defined as no more than one drink per day for

women

and two drinks a day for men.

 

Nutritional supplements and strokes

 

Calcium and magnesium –

These minerals are helpful in controlling *high blood pressure*, one

of

the strongest risk factors for stroke.

 

Congestive Heart Failure

Congestive heart failure (CHF) is a very serious heart condition in

which the heart cannot pump sufficient blood to keep up with the

body's

oxygen demand. Even though the condition typically gets worse over

time,

 

people are able to live with the disease for many years.

 

What causes congestive heart failure?

 

CHF can stem from any disease that causes impairment in the heart's

ability to contract and pump blood, such as coronary heart disease.

 

Other factors include diabetes, an overactive thyroid gland, a viral

or

bacterial infection to the heart muscle, or morbid obesity.

 

When the heart is constantly overworked, it first becomes larger –

as

will any muscle in the body that you consistently exercise and push

hard.

However, over time, the heart eventually tires out, resulting in a

decreased ability to pump an adequate blood supply.

 

What are the symptoms?

 

Fatigue and weakness, particularly when performing physical

activities,

which stems from a lack of *sufficient* oxygen to the muscles.

Swelling in the lower extremities. If the right side of the heart is

affected, fluid builds up in the feet, ankles, abdomen, liver and

legs.

Left sided heart failure can cause fluid retention in the lungs,

leading

to shortness of breath, dizzy spells.

 

Nutritional supplements and congestive heart failure

 

Coenzyme Q10 (CoQ10) – CoQ10 is a powerful antioxidant that has been

shown to be beneficial for heart health by re-energizing the

mitochondria in the heart cells, which is where energy metabolism

occurs. This nutrient is very important for the heart cells of

patients

with heart failure. CoQ10 may also help lower blood pressure.

 

L-Carnitine – This amino acid that is essential for energy

metabolism of

the heart muscle.

 

 

Cordyceps – This medicinal mushroom is a good energy booster and can

improve the workload of the heart

Reishi medicinal mushrooms are also beneficial to the heart and

immune

system as well.

 

http://www.drweil.com/app/cda/drw_cda.html-

command=healthConditionDetail-article\

 

 

 

 

JoAnn Guest

mrsjo-

www.geocities.com/mrsjoguest/Diets

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