Propolis Derivative May be Used to Treat Parkinson's Disease

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Propolis Derivative May be Used to Treat Parkinson's Disease

 

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New findings from France, Turkey and Germany describe advances in

neurology…

 

Study 3: Caffeic acid phenethyl ester blocks 6-hydroxydopamine-

induced neurotoxicity.

 

According to a recently published study from Germany, " Parkinson's

disease (PD) is a neurodegenerative disorder characterized by

progressive loss of dopaminergic (DA) neurons of the substantia

nigra pars compacta…

 

" Caffeic acid phenethyl ester (CAPE), an antioxidant flavanoid, has

antiviral, anti-inflammatory, antioxidant, and immunomodulatory

properties. Recent studies have shown that CAPE has also a

neuroprotective effects in ischemia and low potassium-induced

neuronal apoptotic models, " the authors said…

 

The researchers concluded, " Since a mitochondrial insult is a major

cause for the degeneration of nigral neurons in PD, we hypothesize

that propolis derivatives, in particular CAPE, may have a

neuroprotective effect on those cells and may be a promising drug

candidate to be taken into in vivo models of PD. " …