Guest guest Posted May 10, 2006 Report Share Posted May 10, 2006 Insulin Resistance (high triglycerides and low HDL cholesterol) Insulin resistance is now being recognized as an important and commoncondition associated with heart disease, as well as diabetes andhighblood pressure. It affects an estimated 25-to-30% of the non- diabeticpopulation. It is primarily characterized by high triglyceride and low HDL cholesterol levels, although high total cholesterol may also be seen. Genetic factors play a significant role, but diet and lifestylechanges can make a significant difference. A little background: Insulin is a hormone that facilitates the transport of glucose from the blood into cells where it is used as fuel. When blood sugar rises after a meal, the pancreas secretes insulin into the bloodstream. With insulin resistance, the normal amount of insulin secreted is not enough to move glucose into the cells – thus the cells are " resistant " to the action of insulin. To compensate, the pancreas secretes even more insulin in order to maintain fairly normal blood sugar movement into cells and a normal blood sugar level. The resulting high levels of insulin, however, have several negative effects -- on the enzymes in the liver that produce cholesterol, and on the kidney leading to high blood pressure, as well as on the enzymes in cells that regulate inflammation. Eventually, blood sugar levels rise either because the pancreas stops producing insulin or the cells become more and more resistant to the insulin that is produced. The body's inability to adequately compensate leads to diabetes. Having diabetes, even in the early stages, significantly increases the risk of heart disease. Early diabetes may be the first sign of insulin resistance. Warning signs and diagnosis of insulin resistance? Individuals with insulin resistance are often overweight, with their extra pounds accumulating in their abdomens, the classic " apple " shape.They often have family history of diabetes, high blood pressure or heart disease. Interestingly, although insulin resistance is usually seen in people who are overweight, thin people can also have the problem and be at the same risk for heart disease, high blood pressure and diabetes. The easiest way to diagnose the problem is to take a blood test that looks for the following indicators. A low HDL cholesterol is almost always seen, along with a high triglyceride level. You may also check for a high fasting insulin level. A high uric acid level sometimes accompanies these values. What can you do about insulin resistance? Watch your refined carbs – The classic lowfat diet that was the standard recommendation for preventing or treating heart disease for years can actually make insulin resistance worse. Simple carbohydrates (starches and refined sugars) raise blood sugar levels and trigger the release of insulin. A moderately low carbohydrate diet (40-to-45% of calories) emphasizing low glycemic index sources of complex carbohydrates (those that raise blood sugar levels slowly rather than quickly) is recommended. In general, foods very rich in " fiber " make a greater contribution towards stabilizing gluocse levels. Cut the saturated fats, but keep *monosaturated* fats -- Include considerable amounts of monounsaturated fat (30 to 35% of calories)rather than following a low-fat diet. In this condition, as with high total and LDL cholesterol, saturated fat makes the situation worse. Eat generous amounts (5 or more servings) of complex carbs in the form of organic vegetables and fruit every day. Lose weight if you are overweight. Even small amounts of weight loss can improve insulin resisitance. Exercise – Vigorous aerobic exercise decreases the cells' resistance to nsulin. Eat fish more frequently – The most beneficial are cold water fish like alaskan salmon and sardnes that are high in omega-3 fatty acids. This type of fatseems to improve our cells' response to insulin. Eat small, frequent meals to keep blood sugar levels as stable as possible. --- Nutritional supplements and insulin resistance Coenzyme Q10 (CoQ10) – CoQ10 is a powerful antioxidant that has been shown to be beneficial for heart health by protecting LDL cholesterol from oxidation and re-energizing the mitochondria in the heart cells,which is where energy metabolism occurs. This nutrient is very importantfor the cells of patients with heart failure. CoQ10 may also help lower bloodpressure Alpha-lipoic acid – This antioxidant nutrient improves the cells' response to insulin and can reduce blood sugar levels. Magnesium – Higher insulin and blood sugar levels are seen in people with low plasma magnesium levels and magnesium supplementation improves insulin resistance in animal studies Chromium – It improves glucose utilization in people with high blood sugar levels and improves insulin resistance in animals. Quote Link to comment Share on other sites More sharing options...
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