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> Hello people,

> I've been very busy over the last few days so have not had a chance

> to respond, but today (by accident) I've got more time so I've

> actually got time to respond rather than think about it or start but

> not finish posts.

>

> >I have absolutely no problem with vitex oil being investigated for

> >what it can do. What I have a very big problem with is this

> >investigation being done by amateurs. I do not mean that in a nasty

> >way, fact is to do this job properly and safely requires structured

> >toxicological and efficacy trials. There is no short cut to that if

> >one is looking at possible pharmacological actions rather than

> >subjective psychological effects. Sure, we don't have that research

> >on many commonly used oils, but most of those have been in constant

> >use for hundreds of years without significant toxicological

> >problems. What worries me enormously with oral use of vitex oil is

> >possible long-term harm caused by unnatural over-stimulation of the

> >hormone producing organs.

>

> I agree that the article that Judy posted should not have been

> published in the health food shop newsletter in the first place as it

> only tells half the story, but in the papers that are being/may be

> published, oral use is not recommended.

>

> As to the research being done by amateurs: with any luck, other

> people will read the paper(s) who DO have the money and knowledge and

> time to conduct more clinical trials, and will be spurred on to do so

> by this research. I thought it should be written up so the research

> would not be lost, and later on Aromatherapy Today decided to publish

> it because the editor, John Kerr, liked the way the study was

> conducted (questionnaire basis).

>

> >In reply to your question on how we can progress this issue. The

> >only way forward is proper trials and that can only be done by a

> >professional organisation or company; there are not in the

> >aromatherapy trade capable of funding and organising that. In my

> >opinion the only way this can progress in a safe professional manner

> >is if a large company already in the supplement field decided to

> >conduct trials. However since several already supply the herb in

> >tablets and capsules as well as having already sponsored trials, I

> >have my doubts they will be interested. For example Gerrard House

> >conducted trials on vitex herb years ago and those results were

> >published, as have been several subsequent trials. The Herb

> >Research Founder in Boulder can provide (for a small sum) a whole

> >heap of references on research on the herb.

> >http://www.herbs.org/index.html I highly recommend them for those

> >who want good references to follow up, rather than the typical

> >aromatherapy trade hash.

>

> The CTNM paper (in which Janina Sorensen has written background

> information) calls for further research on the use of the EO and herb

> in menopause (most prior research on herbal Vitex has been to do with

> menstruation difficulties). The conclusion also states, as its first

> sentence, " Clearly this data has to be viewed in light of the small

> number of participants (23), as well as the totally subjective nature

> of both use and measurement of success. " There are 22 references,

> most of which are scientific papers.

> By the way, I don't think you'll find much existing research on Vitex

> leaf. I'm probably going to be very busy again for the next few days

> so will be quiet again but following the discussion.

--------------

Barbara Lucks wrote:

>

> Hi folks--

>

> I'm back on for just a day to briefly address some of the issues

> surrounding the debate over the Vitex Anthology (never presented as a

> study--only as a collection of feedback from others). Fortunately, I

> am not a professional researcher and I funded the whole thing out of

> my own pocket. I have no career to defend here, and I knew the work

> would draw criticism from some scientists--others have praised it.

> Personally, I know how well the oil works for me, and I still get

> e-mail regularly from women who are having good results, so I was not

> looking for validation, especially from people who have no experience

> whatsoever with the oil. I can sit back and appreciate the varying

> points of view.

>

> I thank all of you for your comments. And no, the story is not over.

> I hope it is just beginning, and it does indeed appear that more

> research is in progress. The 23 stories I collected (plus some 12-15

> ladies who have contacted me subsequent to the project) do not

> constitute a large sampling. But a pattern did emerge--a pattern did

> emerge.

>

> For those of you who are scrambling to get a supply of vitex and start

> aggressive personal use, or sell it to your clients with claims of

> likely success. WATCH OUT! This is a powerful and very subtle oil.

> It is still teaching me its tricks, and I have been using it for two

> years. It appears that there may be marked differences in action

> between leaf oil and berry oil, so know which oil you are using.

 

> Also, it is not uncommon to use the oil regularly for 2-5 weeks before

> feeling an effect. Other effects seem quite rapid. All of us who

> regularly work with e.o.'s know these variations, but vitex can often

> take longer than other natural substances to take effect. Research

> to date indicates that it works by direct action on the pituitary

> to normalize progesterone levels.

>

> A woman using vitex oil may experience greater emotional peace and

> mental clarity, improved sleep, stablilized weight, reduction or

> elimination of hot flashes/night sweats, regulation of irregular

> menses, and improved vaginal tone and lubrication. OR she may

> experience worse hot flashes than she ever imagined, unwanted

> bleeding, and technicolor nightmares. My suggestion: if you want to

> try this oil, start with inhalation or highly diluted use in body

> creams. Listen to the messages your body is sending you. Don't go

> selling it to anyone without making sure they know it is a

> experimental oil, no results are guaranteed, and medical monitoring is

> a MUST with any internal use or use of the oil with any form of

> hormonal supplementation.

>

> Don't mix it with birth control pills--you could negate the b.c. pill.

>

> Until two days ago, I was supplying a full copy of my work to anyone

> who posted me privately with a personal need for the information.

> Silly me. Due to abuse of my work and disrespect for the copyright, I

> am no longer supplying this information to anyone. I am looking long

> and hard at how I share--even if I share--the massive amount of

> information that we did NOT have room for in the paper.

>

> Such a format will have to serve the public, will have to honor the

> oil and its power, and will have to serve me. I do know that the

> internet is NOT an honorable place for this work. However, I do want

> to thank the anonymous slimebag who breeched the copyright agreement

> for some great publicity! You know you have a hot property when

> somebody leaks it!

>

> Those of you who want the information, buy a copy of Aromatherapy

> Today--June issue. Perhaps Lowana will let us all know how we can get

> a copy of the nursing journal (due out late in the year) if our

> collaborative piece passes peer review. Aromatherapy journals need our

> support and provide a place to share information in its entirety,

> rather than detached " snippets " zapped around the globe and ripe for

> misinterpretation.

>

> I will sign off tomorrow morning, but can respond tonight to anything

> that I think warrants response. Again, thanks for a lively

> discussion.

> Barbara

-----------

Someone wrote:

>

> Hi folks,

> This is the study that is being published in Aromatherapy Today next

> month, and, in a more scientific form and with more background

> information, is currently being considered for publication in

> Complementary Therapies in Nursing and Midwifery where it is

> currently being peer-reviewed by 2 people.

>

> Although many women were using other therapies as well as Vitex EO,

> they attributed the changes after using the EO to the EO rather than

> the other therapies which could be seen as a base-line constant.

>

> >

> > Someone wrote:

> >

> > This is the article that was printed in our local Helath Food Co-op

> > Newsletter.

> >

> > Menepause Releif Developed From Age-old herb by Amanda Womble,

> > Aromatherapist

> >

> > Vitex agnus castus has been the herb of choice for healing female

> > complaints and hormone imblalnces since time immemorial. Drawings of

> > Vitex appeared in Dioscurides " Materia Medica date 55 AD, and

> > Hippocrates recommended the herb in 400 AD for inlammations and

> > injuries. According to Pliny the Elder (23-79AD), Vitex was highly

> > revered as one of the most important medecines of that time.

> > Today, Vitex is held in the same regard. The indications for the use

> > of Vitex have changed very little since ancient times. Menstrual

> > anomolies and female complaints such as PMS, depression, water

> > retention, mentrual headaches, and low milk production, among other

> > ailments, have been treated successfully with the use of Vitex.

> > In 1994, the first distillation of Vitex rendered essential oil and

> > experts set to work researching its many diverse compounds. Analysis

> > found that the essential oil contained the same compounds as the

> > herb and because of long, slow distillation process, many more

> > unknown compounds were present in the oil that were not present in

> > the extract (tincture)f orm. Danish Physiologist Janina Sorensen

> > reported on her researvh at 4th Scientific Wholistic Aromatherapy

> > Conference last November.

> > Sorensen reported that Vitex in general balances the female sex

> > hormones and counteracts estrogen overproduction.Estrogen domination

> > has been related to several serious female disease including

> > osteoporosis as well as breast and endometrial cancer.

> > Another Speaker at the conferencenoted Aromatherapist Barbara Chopin

> > Lucks, reported on a study that she performed using the essential

> > oil of Vitex with 33 menepausal women. Her preliminary findings were

> > remarkable. The women in the study were experiencing the typical

> > menopausal complaints with varying degrees of severity. these

> > synmptoms inluded but were not limited to:

> >

> > mood swings, depression, personality changes, memory loss,

> > disorientation, difficulty concentrating, hot flashes, night sweats,

> > vaginal thinning, dryness, pain with intercourse, insomnia, heavy

> > or prolonged bleeding, changes in libido.

> >

> > all of the women who participated in the study had some previous

> > experience with using essential oils so the mode of application was

> > let to their discretion. Some women chose only to inhale the oil

> > straight from the bottle while others chose to take one drop

> > internally. Other chose to apply it using a carrier oil, cream or

> > lotion and still others added it to their bath water. Dosages in

> > the study were not specific and the Vitex essential oil was used

> > according to individual preference. I would not her, however, that

> > the essential oil of Vitex is very potent and that very little is

> > needed. (i.e. maximum 5 drops per ounce of carrier oil, cream

> > or lotion, maximum 3 drops in bath.)

> >

> > The women in the study were located thought the United States and

> > Canada. Some of the women were on Hormone replacement therapy and

> > some were taking herbal meneposal formulas. The study lasted for

> > three months, during which time the women keep a journal of their

> > experiences and reported them regularly. At the end of the three

> > months their data was compiled and some of the results follow.

> >

> > > > (to be continued)

> > >

> > > Sorry, folks I am retyping and need a break. Will continue later.

----------

Somebody wrote:

>

> All of the women attributed moderate to major improvement in their

> menopausal symptoms as a direct result of using the essential oil of

> Vitex. They felt that the essential oil relieved their symptoms to

> such a degree that they would continue using the oil even after the

> study was complete. The list of symptoms improved by the following

> percentages:

> .mood swings, depression, personality changes 80%

> .memory loss, disorientation, difficulty concentrating 27%

> .hot flashes, night sweats 64%

> .vaginal thinning, dryness, pain with intercourse 83%

> .insomnia 56%

> .heavy or prolonged bleeding 50%

> .changes in libido 43%

>

> The women who were on HRT experienced so much relief that they were

> able to lower their prescription doses up to 50%. Some women resumed

> having regular periods after not menstruating or 3-10 months. On

> woman even gave the Vitex essential oil to her eleven-year old

> daughter who " was experiencing real hormonal change like hormone

> related headaches. It cleared her headaches completely. "

>

> Another woman reported that using their gave her " balance, a

> peacefulness and relaxation that was much need and appreciated. "

> And another who used the oil reported " more balance in mood swings

> and depression, better sleep, and no more night sweats. "

> One woman reported keeping it on her night stand for immediate relief

> of hot flashes and night sweats just by inhaltion of the oil from

> the bottle.

> It is evident, however anecdotal, that essential oil of Vitex exhibits

> the same balancing action that the research attributes to the did

> berries. However, the oil may be both broader and more refined in its

> therapeutic action. the essential oil may also be used for PMS another

> menstrual complaints for which one would Vitex tincture or capsules.

>

> (Our local health food co-op sells the oil for $22.00 for 5 ml. do you

> know where we can get it wholesale?)

----------

Barbara Lucks wrote:

>

> I seee the Vitex Anthology as an ongoing project, though I am no

> longer doing the work in such a formalway. I get e-mails from time to

> time from some of the original participants, as well as ladies who

> were using vitex on their own or have just started using it. If

> anyone is interested in a copy of the standard information reporting

> form that we used for the Anthology, please post me privately and I

> will send it to you. It has to be snail mailed.

>

> The answer is that yes, we need all the data we can get, though I feel

> that my start needs to be refined and expanded on by someone who is

> better at research than I, and who can dedicate some very focused time

> (and a bit of money) to the project. Janina Sorensen, the

> physiologist who distilled the berry oil, has some great ideas for

> more controlled studies where women are tracked for several years

> through the process, and hormonal levels are measured to determine

> a standard " starting point " . I would be happy to put you in touch

> with her...folks who are medical pros are more likely to have the

> resources to do this research " properly " . Though I must say I was

> touched when several scientists who heard my presentation at PIA took

> the time to tell me that they felt The Vitex Anthology was a very

> sound piece of research.

>

> To quickly answer your questions:

>

> Most of the participants were self-disagnosed as being in the

> perimenopausal to postmenopausal period. Some had lab work to support

> hormonal changes, but, let me tell you, a woman KNOWS when her

> hormones are changing. The ladies were born in the years between

> 1944-1958.

>

> We assessed the impact of nine different syptom groups both before

> using vitex and after three months of use. These symptom groups are

> detailed on the information reporting form the ladies filled out.

>

> The country of origin of the oil and ESPECIALLY the plant part

> distilled is essential informatiion in evaluating the results.

>

> The ladies used the oil in any way they chose, and they reported

> methods of use on the info form. For those wishing to start using

> e.o. vitex, I personally recommend starting with simple inhalation.

> It can take weeks to feel an effect, though some effects are almost

> instant. Both herb and oil act directly on the pituitary to balance

> progesterone.

>

> Use with hormone replacement therapy is dodgy and requires a lot of

> fine tuning. I personally use a combo of soy-derived estrogen and

> e.o. vitex for the progesterone balance. (Yes, I have tried life

> without the estrogen, and we really don't want to go there, at least

> not with me). I need to see my doc about twice a year for monitoring.

> It appears that the use of vitex really skews the progesterone part

> of the balance, and a woman needs to find an open-minded doc to work

> with her.

>

> Also, e.o. vitex, as well as the herb, can REDUCE OR ELIMINATE THE

> EFFECTIVENESS OF BIRTH CONTROL PILLS! Talk about a place you don't

> want to go in your forties or fifties!

>

> The " story " form of The Vitex Anthology will be published in

> Aromatherapy Today, June 2001 issue. A different version, stripped

> down to just the data (and with comparative GC's) is currently

> undergoing peer review for a British nursing journal. This piece

> includes an introduction to the herb, oil and current research

> written by Janina Sorensen, and the entire collaborative effort was

> edited (bless her heart) by Lowana Veal, a biologist. We should hear

> in a few weeks if we have passed peer review. Wish us luck!

>

> So that's where we're at....and the work goes on. Barbara

>

>

A nurse wrote:

> Thank you Barbara,

> Your right about working relationships. I will keep you and this

> list informed. I would like my work reviewed before I start any study.

> Also I wanted to ask you if you still need data...I meet a lot of

> women that are interested in being a part of your Vitex research. I

> need to know what target group that you are focusing on...age (pre or

> menopausal) range...particular symptoms...what part of the plant oil..

> application of the Vitex etc. Can the women already be on hormone

> replacement therapy...will they need to go off their therapy? How

> long will they be monitored for? Let me know... :)

-----------------------------

http://www.kypros.org/Projects/Laona/chaste_tree.html

 

http://www.nutrimart.com/Bulk/Description/agnus.htm

 

http://www.bgbm.fu-berlin.de/scripts/asp/IAPT/ncugentry.asp?name=Vitex

 

http://www.friedli.com/herbs/chasteberry.html

 

http://www.thorne.com/townsend/oct/herbal.html

 

http://breastcancer.about.com/health/breastcancer/cs/chasteberry/index.htm

 

http://depression.about.com/health/depression/library/weekly/aa090500b.htm?iam=d\

pile & terms=%2BVitex+%2Bagnus+%2Bcastus

 

http://herbsforhealth.about.com/health/herbsforhealth/library/weekly/aa050198.ht\

m?iam=dpile & terms=%2BVitex+%2Bagnus+%2Bcastus

 

http://www.health-pages.com/ct/

 

http://www.streetside.com/plants/floridata/ref/v/vitex_a.htm

---------------

> I am a chiropractor and a pharmacist with a background in research. I

>

> have been using oils for several years. I am in the process of putting

> together a project with an ob-gyn to do a study on vitex for PMS and

> menopause. I have several patients using the vitex including my

> mother who after 25 years of hormone replacement therapy had a

> hysterectomy to remove endometrial cancer. She has been using Vitex

> before the sugery and and post-op with no problems.

> My interest began when my wife's sister was diagnosed with breast

> cancer and the tumor grew from nothing to a golf ball in less than a

> month because the MD didn't take her off the hormones. With the

> history of heart disease and osteoporosis in my wife's family, we

> considered HRT a viable option until her sister was diagnosed. Both

> my wife and two of her sisters (one that had the mastectomy) use the

> Vitex to 'regulate' menopause symptoms.

> I have my own theory about xeno-estrogens and their effect on the

> human condition, but that is another soap box to include treating

> menopause as a disease. My experience over the past 9 months shows no

> complications, including one post endometrial CA and Breast CA

> (Ductile). I of course will continue monitoring but the relief my

> patients have obtained has made it worth it.

> I am very curious on the effect of vitex on osteoporosis. Some

> women have stated their osteoarthrits symptoms have decreased as well.

>

> Here is an e-mail I just received tonight:

>

> " On a positive note- I just talked to Cookie (she may call you) She

> has been using the Vitex and wants more - not only -no hot flashes -

> as of the second day - no vaginal dryness, she was actually horney

> and had great sex! I told her to tell you that - hee hee "

>

> This oil has helped many women and out of my group of 30+ patients

> only one had no effect. I have one psychotherapist taking it by mouth

> but most just inhale it (one drop on a tissue) or put it (one drop) on

> their feet, wrist and temples. Usually inhalation stops a hot flash

> dead in it's tracks. Hope this helps!

>

> Dr. XXXXXXXXX

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